| Identifier |
walsh_2012_s2_c2 |
| Title |
TROUBLE READING |
| Creator |
Caroline Tilikete; Virginie Desestret; Nathalie Streichenberger; Muriel Panouilleres; Denis Pelisson; Alain Vighetto |
| Affiliation |
(CT) (MP) (DP) (AV) Hospices Civils de Lyon, Unité de Neuro-ophtalmologie and Service de Neurologie D, Hôpital Neurologique and INSERM U1028, CNRS UMR5292, Centre de Recherche en Neurosciences de Lyon, Equipe Impact, Bron F-69676, France; (VD) (NS) Hospices Civils de Lyon, Service d'Anatomo-pathologie, Groupement Hospitalier Est, Bron, F-69676, France |
| Subject |
Cerebral Cortex; Atrophy; Ocular Motility Disorders; Saccades; Ophthalmoplegia; Supranuclear Palsy, Progressive; Dementia; Dysarthria; Apraxias; Neurodegenerative Diseases; Inclusion Bodies |
| History |
A 73-year old female with a 1-year history of progressive visual difficulties and impairing reading. |
| Pathology |
TDP-43-positive neurites with extraneuronal neuromelanin pigment deposits and TDP-43 positive glial cytoplasmic inclusions. |
| Disease/Diagnosis |
Frontotemporal dementia |
| Clinical |
Normal VA; Upward supranuclear vertical palsy; Horizontal saccade deficit; Apraxia of lid opening |
| Presenting Symptom |
Progressive oculomotor impairment |
| Neuroimaging |
MRI; Brain SPECT; DaTSCAN |
| Treatment |
N/A |
| Date |
2012-02 |
| References |
1. Garbutt S, A Matlin, J Hellmuth, AK Schenk, JK Johnson, H Rosen, D Dean, J Kramer, J Neuhaus, BL Miller, SG Lisberger & AL Boxer. Oculomotor function in frontotemporal lobar degeneration, related disorders and Alzheimer's disease. Brain, 131, 1268-81, 2008. 2. Litvan I, JJ Hauw, JJ Bartko, PL Lantos, SE Daniel, DS Horoupian, A McKee, D Dickson, C Bancher, M Tabaton, K Jellinger & DW Anderson. Validity and reliability of the preliminary NINDS neuropathologic criteria for progressive supranuclear palsy and related disorders. J Neuropathol Exp Neurol, 55, 97-105, 1996. 3. Paviour DC, AJ Lees, KA Josephs, T Ozawa, M Ganguly, C Strand, A Godbolt, RS Howard, T Revesz & JL Holton. Frontotemporal lobar degeneration with ubiquitin-only-immunoreactive neuronal changes: broadening the clinical picture to include progressive supranuclear palsy. Brain, 127, 2441-51, 2004. 4. Steele JC, JC Richardson & J Olszewski. Progressive Supranuclear Palsy. A Heterogeneous Degeneration Involving the Brain Stem, Basal Ganglia and Cerebellum with Vertical Gaze and Pseudobulbar Palsy, Nuchal Dystonia and Dementia. Arch Neurol, 10, 333-59, 1964. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
44th Annual Frank Walsh Society Meeting |
| Relation is Part of |
NANOS Annual Meeting 2012 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2012. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6ns0xrc |
| Setname |
ehsl_novel_fbw |
| ID |
179083 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6ns0xrc |
