Progressive Visual Loss in a Man with Leukemia (Audio)

Update item information
Identifier walsh_2009_s1_c1_mp3
Title Progressive Visual Loss in a Man with Leukemia (Audio)
Creator Lee, Michael
Subject Bone Marrow Transplantation; Myeloablative Agonists; Blindness, Cortical; Neurotoxicity Syndromes; Leukemia, Myeloid, Acute; Demyelinating Diseases
Presenting Symptom Blurred vision OS
History A 48-year old male diagnosed with acute myeloid leukemia: Tx BMT.
Clinical VA: Light perception OD,Hand motions OS
Neuroimaging MRI
Pathology White matter vacoulization, axonal spheroids, macrophages in medulla and spinal cord.
Disease/Diagnosis Neurotoxicity secondary to fludarabine administration
Treatment Myeloablative agonists
References 1. Ding X, Herzligh AA, et al. Ocular toxicity of fludarabine: a purine analog. Expert Rev Ophthalmol. 2008;3:97-109. 2. Chun HG, Leyland-Jones, BR, et al. Central nervous system toxicity of fludarabine phosphate. Cancer Treat Rep. 1986;70:1225-28. 3. Warrell RP, Berman E. Phase I and II study of fludarabine phosphate in leukemia: therapeutic efficacy with delayed central nervous system toxicity. J Clin Oncol. 1986;4:74-79. 4. Cheson BD, Vena DA, et al. Neurotoxicity of purine analogs: a review. J Clin Oncol 1 994; 12:2216-28.
Relation is Part of Session 1, Case 1, Walsh Session, NANOS 2009
Contributor Primary Lee, Michael
Contributor Secondary SantaCruz, Karen; Brace, Jeffrey; Mckinney, Alexander
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2009-02-22
Type Sound
Format audio/mpeg
Source 41st Annual Frank Walsh Society Meeting
Rights Management Copyright 2009. For further information regarding the rights to this collection, please visit:
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
Language eng
ARK ark:/87278/s6g73hmp
Setname ehsl_novel_fbw
Date Created 2012-06-06
Date Modified 2017-02-21
ID 179069
Reference URL
Back to Search Results