| Identifier |
walsh_1990_s1_c2 |
| Title |
Visual Loss in a 59-Year Old Man |
| Creator |
John W. Gittinger Jr. |
| Subject |
Pupil Disorders; Scotoma; Recoverin; Carcinoma, Small Cell; Neoplasm Metastasis |
| History |
A 59-year old male with a sudden onset of visual disturbance. |
| Pathology |
Small cell undifferentiated carcinoma with extensive interstitial and lymphangitic spread. |
| Disease/Diagnosis |
Cancer-associated retinopathy |
| Clinical |
VA: 20/15 OD, 20/25 OS declining to 20/25 OD, 20/200 OS; RAPD OS; Intraocular pressure: 16 OU |
| Presenting Symptom |
Shimmering visual distortions |
| Neuroimaging |
CT |
| Treatment |
Corticosteroids; Antineoplastic agents; XRT |
| References |
1. Sawyer RA, Selhoist JB, Zimmerman LE: Blindness caused by photoreceptor degeneration as a remote effect of cancer. Am J Ophthalmol 1976; 81:606-613. 2. Keltner JL, Roth AM, Cobb CA: Steroid responsive blindness. 13th Annual Frank Walsh Society Meeting. Houston, 1981. 3. Komguth SE, Klein R, Appen R, et al.: Occurrence of anti-retinal ganglion cell antibodies in patients with small cell carcinoma of the lung. Cancer 1982; 50:1289-1293. 4. Buchanan TAS, Gardiner TA, Archer DB: An ultrastructural study of retinal photoreceptor degeneration associated with bronchial carcinoma. Am J Ophthalmol 1984; 97:277-287. 5. Xlingete TG, Burde RM, Rappazzo IA, et al.: Paraneoplastic retinopathy. J Qin Neuro-ophthalmol 1984; 4:239-245. 6. Grunwald GB, Klein R, Simmons MA, et al.: Autoimmune basis for visual paraneoplastic syndrome in patients with small cell lung carcinoma. Lancet 19E5; 1:658-661. 7. Grunwald GB, Kornguth SE, Towftghi J, et al.: Autoimmune basis for visual paraneoplastic syndrome in patients with small cell lung carcinoma; Retinal immune deposits and ablation of retinal ganglion cells. Cancer 1987; 60:780-786. 8. Thirkill CE, Roth AM, Keltner TU Cancer-associated retinopathy. Arch Ophthalmol 1987; 104:372-375. 9. Van Der Pol BAE, Planten JTH: A non-metastatic remote effect of lung carcinoma. Documenta Ophthalmol 1987; 67:89-94. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
1990 Walsh Proceedings |
| Relation is Part of |
Case presented at the NANOS 1990 Walsh Session, February 16-17 Contributor Primary |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6p84fqs |
| Contributor Primary |
Gittinger, John W., Jr. |
| Contributor Secondary |
Rizzo, Joseph; Thirkill, Charles E.; Roth, Alan M. |
| Setname |
ehsl_novel_fbw |
| ID |
178781 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6p84fqs |
