| Identifier |
20210222_nanos_posters_139 |
| Title |
Pupillometry Findings in Isolated Rem Sleep Behavior Disorder |
| Creator |
Chiara La Morgia; Martina Romagnoli; Fabio Pizza; Francesco Biscarini; Marco Filardi; Vincenzo Donadio; Michele Carbonelli; Giulia Amore; Gaetano Cantalupo; Jason Park; Michele Tinazzi; Valerio Carelli; Rocco Liguori; Giuseppe Plazzi; Elena Antelmi |
| Affiliation |
(CL) (MR (VD) (MC) (GP) IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy; (FP) (FB) (MF) (GA) (VC) (RL) Università di Bologna, Bologna, Italy; (GC) (MT) (EA) University of Verona, Verona, Italy; (JP) University of Illinois, Chicago, Illinois |
| Subject |
Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid); Pupil |
| Description |
Melanopsin retinal ganglion cells (mRGCs) are crucial for non-image forming functions, including circadian rhythm photoentrainment and regulation of sleep and pupillary light reflex (PLR). Chromatic pupillometry, using light stimuli at different wavelengths, allows isolation of rods, cones and mRGC contribution to PLR. The presence of mRGC-mediated PLR impairment and mRGC loss in postmortem retinas have been demonstrated in PD, and we recently described reduction of the rod-mediated transient PLR in AD suggesting a possible mRGC dendropathy. Idiopathic/isolated REM sleep Behavior Disorder (iRBD) represents the strongest prodromal risk factor for α-synucleinopathies. |
| Date |
2021-02 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2021 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2021: Poster Session III: Cognition, Mood & Neuro-degenerative Disease |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2021. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6f24vdg |
| Setname |
ehsl_novel_nam |
| ID |
1675929 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6f24vdg |
