Elias Hicks Blackburn Journal, 1903

Original bound journal of Elias Hicks Blackburn, 4.5" x 5.75", 1903.

= 2Ri REETLSe sst 5= — AAA A ayye,2Gya ae 7 aaed On ' 5 , , Mae at or dune: oS 3 ” PtDoe ‘ oe . Solel eAy w wee y i Rue PATRI tm re 7 Lab raiehaNs Lae a vi ene Pd IROns mK 2 t= > BY3 SS Sr s) WS Mate aey n ODO SAS eee f This book belongs to 4f found please return to owner. 58 [76 4 e \ GLaog 0 J THE Late Pror. Dr. ADoLtF KUSSMAUL, HEIDELBERG, GERMANY. COMPLIMENTS OF M. J. BREITENBACH COMPANY 53 WARREN STREET NEW YORKCITY YEAR BOOK 1903 Press or B,. W. HUEBSCH New York City iS Leves 3 aw1t Okeiihucsday,ayh 1 DAY PAST 364 TO COME September6, 1901. Dr. E. Lewy, Vienna, says: “Your preparation is often prescribed by me and has always met my expectations. It is particularly useful in greatly exhausted and very anemic children, as well as in cases of measles, whooping cough, and anemia, sinceit is easily digested, increases the appetite, and hastens convalescence, as manifested by a rapid increase of bodily weight.” JI UF Hofer FF pu no Oor oe ok [eh eane Hise fye eh n rrLen as a e "Ocume te ios ayDaresve a i QS C. Lenn |7ERY Oy fame aga Sf ne J poe ohn Y b- J | (A har LRA+ pt cata Ay nev peal lh ? = Ce GDh ae oe ene— Vlevyv9-4 Opn AP) our A apo Ma ahiore Goren hie Hi tL pb (rer Om the fret an (=) Dr Ao Alot CD o~e@ ik coayhenea as A oe Oy apatbr 7 Friday, January 2 2 DAYS PAST Saturday, January 3 363 TO COME 3 DAYS PAST Abstract from Editorial Medical Century, issue of August, 1902. Abstract from Dr. E. C. Hill’s paper ‘‘How to Assist : Young Girls to Womanhood.’’ Journal, July, 1902, “‘What has been the clinical success of this ‘Pepto-Mangan (Gude)? It has been found that it stands at the headof all preparations of iron in the treatment of anemia, and especially in chlorosis. “It suits especially those cases where anzemic heart murmurs are present, and where in females the menstrual function is irregular, deranged in quantity and quality or entirely absent, and where 4 V Brooklyn Medical ‘‘Menstruation is or should be a perfectly physiologic process. The virgin disorders of menstruation of whatever nature are nearly always dependent upon the defective nutrition of the reproductive organs, and this in turn upon a blood supply insufficient in quality or in quantity. In the great majority of cases, therefore, our efforts to aid nature in effecting the transformation of the girl into @ woman, should be in the line of a happy balance of nutrition between thespecial female organs and the body as a whole. vicarious hzemorrhages occur as a result of the anzmic condition.” f 362 TO COME t Me al L ty ‘{ @_+4 oe “4 et f h-4_ } ? / ~ . y ‘ * J - : id AY Cu f SH (VS ATA raMN lt PY\A r _ (Y4 So e Se ihe 1 yf Ay Lk Ay of (A , ve Sunday, January 4 4 DAYS PAST a Monday, January 9 361 To CoME i July 30, 1901. 5 DAYS PAST Dr. Zekendorf, Royal Vineyards, Prague, says: ‘The Pepto-Mangan (Gude) has been well tolerated, and, unlike mostiron preparations, has a direct stimulating effect upon the appe tite. The improv ementof the anemiccondition against whichit 2s used occurred w ithin a short time. " 360 TO COME . From the ‘*Medical Times and Register.’’ ‘‘Onlike all other compounds of iron anl manganese, Gude's Pepto-Manganis pleasing to the eye and agreeable to the palate. In colorit resembles clear, dark sherry, aromatic and non-astringent. and in taste it is mildly It is quickly taken up bytheblood, an increase in health and weight is generally noted within a w eek Opn wt after its use has begun. It produces a vapid increase in the red blood corpusc les, does notin jure the teeth, and can be given in milk.” WoKuklCatv 07 om pretium of Forms K ( fy lV, a5 tNn he Gor pol ocd GY, <2, Jb s-d Oe yw ss yy 1pe be ands) MM, ju” J. In An ih Choa IGE conte um Neer 7 Orpnnwy le eee 6 DAYS Dr. J. Tuesday, January 6 PAST 359 TO COME Von Ferroni, Wednesday, January 7 7 DAYS PAST August 18, 1901. Surgeon-General in the Imperial July 7, 1901. Dr. Class Larsen, London, Says: “T have tested Pepto-Mangan (Gude) with excellent therapeutic Army, Goestling a/d. Ibbs., Says: ‘*T have tried the samples of Pepto-Mangan rachitic children. Among the ferruginous (Gude) in anemic and preparations known to me Pepto-Mangan (Gude)is deserving of the preference, because it is readily taken by patients and does not in the least disturb the stomach. Its effect was very good, so that in future I shall resort to Pepto-Mangan (Gude) alone in appropriate cases .” 358 TO COME results.” July 29, 1901. Dr. Bisig, Bullen, Switzerland, says: ‘‘The Pepto-Mangan (Gude) has afforded me very excellent and f- : / 7 ~~) prompt results.” i AS J Ps —=. Y2na~we ym i War Jf - i {stg J igi F y7 / ¢ & ; jpt o age oe, hae A a ] a JA a | se J \ IDR A A / Givi V4 & ae Ve, 4 “A kd Af) KI— ae fee 2) (1 AQHU a A af “| i1 7) ZA : ¥n ae wo G f : 4or y s O77) @) 2 = FY lr 4er ff 7 Ae 2 0A (Oy J /) c etsanit mn J ed t Ve VIX g , hao OY Z 4-9 “A4 ae a , £: CU 7 y Ake a2 : a 4; / ? Lr q hh Thursday, January 8 S DAYS PAST Friday, January 9 357 TO COME In submitting this Report, I wish to.‘summarizethese 9 DAYS PAST conclusions: “that Pepto-Manganis a highly available preparation of iron on accountofits liquid form, pleasant taste, noncorrosive action on the teeth and unirritating effect on the digestive organs, admitting thus of easy gradation of dose, easy administr ation to children and avoid- ance of unpleasant effects in all classes of patients.” The above are the closing remarks of Samuel Wolfe, A. M.. AD, Fhuiladelphia, Pa. eadae hisc Linical reporeonGude’ sPPepto: Mangan, eeas Lp : a 4 Kon Dy c Lat ee Hs GL be het 356 TO COME June 4, 1902, Dr. Francisco Martinez de la Torre, Cadiz, Spain, says: ‘‘The results derived from Pepto-Mangan (Gude) have been highly satisfactory. Thefirst case wasthat of a lady suffering from chloroanemia and irregular menstruation preceded by attacks of pain. These have now disappeared, and the menses have becomeregulary The secondpatient was convalescing from malaria, and a noteworth. fact was the rapidity with which the preparation effected a gain of strength. In both cases it was well tolerated by the stomach.” Va es Gi0h? rwhee Ja, yAs a ‘ cif b le Gan fori Dd ba M of oe Aa oe WA G e t o ho {Y h,ib, Om Long Vas st—-O I A ce : cm sr L he / p—f /} (LT Lezol a Ha Lag A 17 a. Paahfoe of ayyfVA Cy a gon gf ve 9 tu diver < LyOud Attod ee O_*XBde (Ut eee January 11 eetrere January 10 10 DAYS PAST 11 |DAYS PAST 355 TO COME Dr. Ww. Seshlessinger, ‘Vienna, says: ‘‘Tt affords me much pleasure to inform you that my experience with Pepto-Mangan (Gude) has been very favorable, the patients tolerating the preparation very well; in fact, they took it gladly. In all cases I was able to observe an improved appearance and an increase of appetite and weight. I, therefore, employ your preparation in all cases in whichiron is "indicated, both in children and adults, and have recommended it tomy colleagues.” Editorial ‘An Efficient IronPreparation.” (From Milwaukee Medical Journal, January 1901.) ‘One of the most reliable preparations in this respect is Gude’s Pepto-Mangan.”’ Dr. Francisco Cordero, says: t s r o H u l U t e h s e Ma ‘Tn all cases in which I have had occasion to use Pepto-Mangan (Gude) it has given me excellent results of which Iampleased to wtf 9 vic eee Wed gmat iy & 2 = pron Yi HioA Cobol hat A ; Gu Cc Chl. x 4 ¥ Fra te 4 / fi N\¢ A / pre /y oy J (Whe C Wy Oeae Yn Jie hy f GLCma hl clay Hn irae 1) / aes ATs to ee He Hee tL Cee ) be cySp L- y t fosog 0) o)deny Ly yma Lokof CL a4 oe —r sae Jp.v a Va‘ Car YY Wy oh ae yy 1A dr ; d y diand he Js on us a Quprree 4 i ot -A (Hite UA oe Un 4 weVg Cy CQw aD £1.As od Q Ms O eae Bae VW;ye Lii eee F fF Dera i a /Jyn ke.ae o 7 POG | VN Ir , 3| hap ¢ F wyNy I Lv4 ud beer, J 2 1&Ay,.A117 NA (A 354 TO COME it io aie QVLecu Sf ( hat leof yaa we se ee Tuesday, January 13 Monday, January 12 12 DAYS PAST 13 DAYS PAST e In the ‘‘Memphis Lancet’’ issue of April, 1900, appeared a paper under the heading ‘‘ Why I use Pepto- Mangan (Gude).’”” An experimental demonstration, by William Krauss, Ph. G.[1.D. The closing remarks are in these words: ‘“‘Therapeutically, it does not nauseate, constipate, discolor the teeth, precipitate the digestive agents, nor become inert fromcontact with them. As tothe clinical results, I need not add anything to the manyreports alrPay on record,” AL 1 2) 352 To COME 353 TO COME Dr. Gustav Bondy, Vienna,says: ‘Permit me to say that the supply of Pepto-Mangan (Gude) which you kindly sent to me has been employed in a case of chlorosis in whichI had previously administered a numberof other iron preparations, without any material benefit. After the use of your preparation I was able to note a remarkable imprreverent!7 L214 é] mn of Av Asieeee Ly AtLy Jf PL C0 1 of Orolige ¢ ~~ A ve wv 4 LIee 1 ; 7 of ) LY AY bo CA 1% od os h KA111 he Y |f COMRLSF A” e h a pr Coen pol Urark (Cvake e S of fis: me Cy Ly y)0 “a edt$20 af or } Grherpes Le Os See ge tt bt~ At op MAA. AYow Cu ree fr ote2 : Wednesday, January 14 14 DAYS PAST 351 TO COME IN ANAEMIA SPLE the blood changes of the chloro-anemie type. There is marked chronicity extending over manyyears witha greatly enlarged spleen. There is leuchemia with greatly reduced amounts of heemoglo bin, Hemorrhages usually occur in the stomach on account of the close anatomical relationship of the stomach and engorged spleen, PeptoMangan (Gude) increases the amount of hemoglobin and rich newblood; repairs all waste from hemorrhagia. Tests builds by the use of the Heemocytometerandclinical observation provet he efficacy of this preparation. aCo 15 Thursday, January 15 DAYS PAST 350 TO COME From the Clinical report of Dr, Hermann Metall, Vienna , Austria, Assistant Physician to the General Polyclinic, CASE. I.—Mary B, 16 yearsold, has complained since a week of general debility and lassitude. She is very pale andrestless, has no appetite, and suffers from headache and a feeling of pressure in the stomach, She is constipated, and the menses are irregular. Diagnosis, chlorosis, (See table otherside.) { . VAL JD~A nS} A . / ie T 4 t Y yi J (AWerewdt J A be 4 | A kit : f Fi £: ug / é j Friday, January 16 16 DAYS PAST 349 TO COME 17 DAYS PAST Dr. epiuaien ‘Motall_conteaast. CASEI. ted Blood Cells | Hemoglo- in Cubic bin per Millimetre. cent. tly | Weigte | Saturday, January 17 348 TO COME Dr. Hermann Metall—Continued. Case II.—AnnaH., 23 years old, has suffered for three years from chlorosis, with irregular menstruation, palpitation of the heart, a | Therapy. 7 feeling of weakness, and occasional syneepe. Physical examinatic n showedthe presence of anzemic murmurs overthe heart, as well as a venous murmur ; no fever or cedema, | August 2..... 2,480,000 August 9..... 3,212, 000 August 16.... August 24.... September2.. | 20 |Pepto-Mangan 25 4, 020,000 4,300,000 5,000,000 30 40 50 51.3 3. | | | (Gude), | Red Blood Cells in Cubic one Millimetre. tablespoonful three times daily. Hemoglo-| bin per cent. | ; Bodily Therapy. | Weight. tape | | After a week, the appetite was good, no headache; at the end of the second week, no further disturbances ; menses not painful, and lasting only three days (formerly five days). After four weeks, the patient discharged cured. Pepto-Mangan August 4..... | August 29.... 3,750,000 4,010,000 September 14 55.5 57.9 ) 4,200,000 bos | (Gude), one tablespoonful three times daily. Appearance of menses after absence of 12 weeks; subjective dis- Yo Py u of \/ tur bances have disappeared? (ph U of , Ee fet pe Vet £Qerol oeo)re. f 4 A Yru k ‘ rom an. ‘a ‘ 0 lot thar pe U tA-t— ban Wf a A Madictishn Fa co foagph LH Teee s , — -? L, f; p f pa aria | ort Vay e yy, q ) 00-20 é bohag/ 0 reAk ttCoss on Oege JM, en , MN LA. CAMA fy f Aiberrns Hon LY fb ry) sd 4 . Sf ee K-vtha-1 OF A e A\AA4 i Mon Yy of Cy (* — (oA 4 at ews UAAY , Cr we iz x Au — ( ? Sunday, January 18 3 DAYS PAST Monday, January 19 347 TO COME 19 DAYS PAST Dr. Hermann Metall—Continued. f CASE III.—M. W.,.16 years old, has suffered since a year from headaches, dypneea, tinnitus aurium, vertigo, and ae disturbances. ' TASE pet 346 TO COME Dr. Hermann Metall—Continued. There was marked pallor of the face and of the mucous membranes; systolic murmurs over the mitral and pulmonary valves, with dilatation of the heart. No fever ; spleen not palpa— t ied toed Cele Hemoees) Reality ble. f satiecinen ae Weight. Diagnosis, severe chlorosis. (See table otherside.) _ cx eee ¢ (Le August 5..... 2,250,000 25 August 13.... 3,200,000 30 August 16.... August 23.... September1.. 3,350,000 3,530,000 4,250,000 35 40 45 | | } ! CLOT OU ON Ay Or orgr or or GO & OL W id | Pepto-—Mangan (Gude), one | tablespoonful | three times { daily. } { The subjective symptoms rapidly subsided, the appetite improved, and the stools became regular. The menses reappeared in the second week of treatment after having been absentfora year, ’ 4 —— bru? ar Tuesday, January 20 20 DAYS PAST WACerossn January 21 21 DAVS=PAST 345 TO COME Dr. Hermann Metall—Continued. a4 TO COME re Hernan Metallacodeaded: CASE IV. CASE IV.—M. P., 15 years old. Menses absent since one-half year; always scanty. Vicarious hemorrhages from the nose. Sincethree months the patient has suffered from dyspnoea, vomiting, cardiac palpitation, general weakness, headaches, feeling of dulness, and sleeplessness. Physical examination reveals anzmic murmurs, moderate dilatation cf the heart, venous murmur, (See | | Red Blood Cells |Hemoglo-) in Cubic bin per | | Millimetre. cent, | pogily | Weight. | table other side.) Therapy. | August 5..... August LO ool. 47, 47, | 3 48.3 | (Gude), 35 40 45 50 49, 49, 6&2. bey | | | | tablespoonful three times daily. 2,400,000 3,600,000 20 20 August 16. 3,850, 000 August 93. August31. Se»ptember’We September 14,|| 4,250,000 4, 700, 000 5,000,000 5,200, 000 | | | Pas | |Pepto-Mangan one bail After the first week improvement set in; at the end of treatment disappearance of all disturbances. Increase of bodily weight, 12 pounds, / eeeEA Teteene— tteee L sot 7 Riu oy — \ Bee S oe) ; , ye ree y Ln LAW Tr \ i \ mS \ W) {} Lox: Og er A \ { JHE vu at ee Ge Lage oe es sof “Pe A _ coe January 22 22 DAYS PAST Friday, January 23 343 TO COME Dr. Hermalin|Meinl Gouna, CASE V.—J. K., 18 years old. Chlorosis. Anazmic murmurs, cardiacdilatation, loss of appetite, insomnia, general lassitude, and headaches. | ' Red Blood Cells | Heemoglo-| in Cubic bin per Millimetre. August 10....| August 24....| September12, | cent, 2,% 35 5 3, | | BOSir. ache, vertigo, tinnitus, and constipation: anzmic murmurs and oe | Teh pt [Pepto-Mangan’ | (Gude), one | tablespoonful | three times 52. ie Ce ea Therapy. | daily. ) mtic Lis wah) f) OF th wy Cat W 4 kaon oer c ee fo, { : V (t, y Oferuol Ya Comme lv LA 4 “fnWoUre f FT4 Vv if; f4 At of a? ’ Orucl ee 342 TO COME Dr, Hermann Metall—Con“a tied.” CASE VI.—A. N., 19 years old, has suffered from chlorotic disorders since two a Improvement occurred under a milk diet and a sojourn in the country. Since five months the patient again complains of disturbances ; palpitation of the heart, lassitude, headvenous humperceptible. TI At the endof the first week appetite vigorous; headaches had sub sided. At the endof the fourth week no disturbance of any kind. oy a a4 23DAYS PAST I Pe SMh2 Vv f \-7 ADL, Q of 9 f /) to YLlA ff f q Pri » f AA f dh ‘Y Cty WG, eh Va oe fT > (AZ, nee ’ ot LAA (See table otherside.) Saturday, January 24 24 DAYS PAST 3 341 TO COME Dr, ‘Hermann Metall—Continued. CASE VI. Red Blood Cells | HemogloSteen es Pe odily September 7..| September a 4,500,000 4,100,000 4,000,000 3,950,000 4,200,000 | | bin per cent. | Weight. Orororor or -~2 oO2H He CO August 17.... August 25 August 31.... in Cubic Millimetre. 340 TO COME Dr, Hermann Metall—Continued. CASE VII.—J, R., 20 years old, has suffered from chlorosis since | | Sunday, January 25 25 DAYS PAST Therapy. two years, Status presens; General lassitude, palpitation ofthe heart, a feeling of pressurein the stomach, difficulty in breathing ; mensesirregular as well as dysmenorrhea. In thelast three months all the disturbances have become more intense. (See table other side.) A f Pepto-Mangan irrfur (Gude), one tablespoonful three times daily. rs ff VT ns / AIX J ( ‘J QMn kts4 The subjective symptoms diminished after a few days. The disturbances disappeared, the appetite improved, and the stools became regular. KHUm a 7, i /) SoA 6 / ho 1] fg 4A ft Y Serer /) bd woe TA f A, At Wy {7 Lp lhr—- ae ff, MN A_A AA (on qd _— A. yor and , | . D. he 5S. A> Sur mn 4 Monday, January 26 26 DAYS PAST Tuesday, January 27 339 TO COME 27 DAYS PAST Dr.Hermann Metall—Continued. Dr, Hermann Metall—Continued. CASE VIL. Hemoglo-}| bin per in Cubic cent. Millimetre. | Bodily we; | Weight. | Therapy. Red Blood Cells | HemogloBodily in Cubic bin per | weicht | | September18. | September27. | 80 35 40 50 55 60 ~ he | Millimetre. over September12. | | Red Blood Cells |Pepto-Mangan (Gude), one } oror August 22.... August 26.... September 5. .| CASE VIII.—L. N., 19 years old, complains of headaches, cardiac palpitation, vertigo ; scanty menses. BEKSSS | Date, 338 TO COME j tablespoonful three times daily. | cent. September13.| ‘ é |Pepto-Mangan E ; October 1.... oF. 5 | | (Gude), one tablespoonful three times daily. , BE The subjective disorders have vanished ; menses more abundant. L- 7 ies | August 28.... 1 The disorders have disappeared, the appetite is good, and the bowels regular ; no anemic heart murmurs. | Wednesday, January 28 23 DAYS PAST 337 TO COME 29 DAYS PAST Dr. Hermann Metall—Continued. CASE IX.—J. M., 16 years old, has suffered since two months from palpitation of the heart, dyspnoea, feeling of pressure in the stomach, vertigo, tinnitus, and headaches. Thereis a slight cardiac palpitation, with systolic murmurs and a venous hum. and constipation are present. since a year. | in Cubic Millimetre. Anorexia The menses have been irregular | Red BloodCells | Hfemoglo- Date. | bin per : 336 TO COME Dr. Hermann Metall—Continued. CASE X.—Z. F., 30 years old, had a miscarriage two weeks previously, with profuse hemorrhage. After a month’s treatment completely restored to health, and an increase of weight of four pounds. CASE XI.—A. N., six years old, rachitis and anemia. Under treatment an increase of weight of two-thirds of a pound. Much | | Thursday, January 29 better appearance. Therapy. : CASE XII.—J. W., 30 years old. | — So 3 ed > > Oo “eo OO “2 OF September29. | Ho Rass LS SS 1 September2.. September11. September20. | 35 | Pepto-Mangan 40 50.5 BB 52. 50 51. | | | | (Gude), one tablespoonful three times Menses regular ; bowels normal ; no disturbances. #® a7 our bk ur me QBhigordUe eel r) A YALL Pulmonary tuberculosis and anemia. After two weeks’ administration of Pepto-Mangan (Gude), an increase in weight of two pounds and an increase in hemoglobin of FIFTEEN percent. A Friday, January 30 30 pee FA S Beer ace 335 TO COME Dr. Hermann Metail—Continue d. CASE XIIl—K. L., 50 years old. chexia, and ane mia. Cancer stomach, caDuring three weeks’ useofofthe Pepto-Mangan (Gude) the patient felt. better, the appe tite had improved, andthere was an increase of weight of two-thirds of a pound. CASE XIV.—A. B., 14 years old. Chlor cent. After two weeks’ treatment. hemo osis ; hemoglobin 40 per globin 85 per cent.; disappearance of all disturbanc es, CASE XV.—F. K., 18 years old. Chlorosis ; hemoglobin 35 per cent.; after two weeks’ treatment 50 per cent. CASE XVI.—E. J., five years old. Anzmia follo wing scarlatina. After eight days’ treatment with Pepto-Ma ngan (Gude) the patient developed a vigorous appetite, and recov ered so rapidly that he could be discharged cured at the end of the second week. y 31 Saturday, Januarte 334 TO COME I DAY ‘S$ PAST ‘ = BLOOD ‘ DE aE a e - nartion “Ania of the up thedam ay become brain degeneracy. | Build coent 1 force of > the fun al! force © hod con e — S denotes a lack slood. ¢ a pe bui ld up the dit e ion . “acy . like mora l 2 deg 1 deg ene eneracy, 11Kke ave agate s the > the ne the body. Blooe blood leav es ; kened eer. ed con ‘esist. 5 A weaken cond itio n of the dit ion ontD100 isea agious dise ses. ases een « nt i a to malarial affectio ns St eae the blood. to epto-M angse (Gu Pa Ma forsce aeiode oxygen carrying ae de) is the snevvita , l Iti a nut proa as A h ae its normal germicidal potency r all dise =p, ducing eac ases agent After typhoid fever and al -ed. systematic reconstruct(Gude) is administered 8. pto Man gan when P repto-wanga’ is ion is rapid. Ww Sgt a , Be os = tH Dt slr7vy) ; // ML-vt ‘a9 Zh k Ad be ff Do ho htV Khe 32 A ereassind February4. ee Dr. K. Richter, Vienna, says: DAYSS PAST PAST July 25, 1901. ‘ : “IT have used Pepto-Mangan (Gude : ) in a case of: markedchlorosi<. in which other preparations had previously been badly tolerated, was well borne and its administration proved most suceessful,” Sores es vt 1: - i Monday, February < ee 332 TO COME July 31, 1901. sor Neiss Néisser, Privy Councillor, Bresiau, says: Professor Privy Cou ’ ‘‘Ta have been well: satisfied the results from the use ay coalways AyYS Vocr F : with . as Shee 4 ane ef£ ¥ your Pepto-Mangan (Gude), and continue to prescribe it in ap rh a 5 \ ) ° a propriate cases. <= Seles 4 ae ae fo (—L) (LV) lg AAA —— oe 4 CY ie = Sf 4: } ge epee ae ‘a 7 ie / ff “oy raze _ 3+ uesday, February 3 DAYS PAST re 331 TO COME September 1 Dr. F. Esser, Eggenstein, Baden, says: ~ a . : 1901. 3 , _ +i my opinion Pepto-Man gan (Gude) is the best and mos t efficicient of the many iron prepar ations.” : March, 1902 ! ‘ ‘Medical Times and Regist er,”’ Philadelphia. ° “Gude's Pepto-Mangan remedies.” e stands at the head of this : class sit of Wednesday, February 4 330 TO COME 35 DAYS PAST June 4, 1902. Dr. Francisco Cortes, Palma de Mallorca, says: ‘“‘T have used Gude’s Pepto-Mangan in the case of my daughter, whois of alymphatic nervous temperament andsuffers with anemia due to her rapid growth. She had previouslytried several ferrugin- us preparations without being abie to complete the treatment on account of the gastro-intestinal disturbances to which, they gave rise. Under the use of your preparation, which I am administering in small doses, she already manifests an improvement, as shown by the ruddy color of her cheeks; her stomachtolerates it well; her lizestion is good, her appetite has increased and the exercise she takes does not tire her now.” Friday, February 6 Thursday, February 5 36 DAYS PAST 329 TO COME From ‘+ Columbus Medical Journal.’’ ‘That Gude’s Pepto-Manganis a true hemapoietic agent is demon. strated by a serie s of cases in whichthe blood count at the beginning ot treatment revealed a diminished number of corpuscles. In none of these cases did wefail to get an increase by its use of the red corpuscles, and also in the percen tage of hemoglobin.” 4 ( okel we 4 26 0k 328 TO COME Oyn7 af August 18, 1901. Dr. Heinicke, Gotha, says: asure to inform you that the Pepto-Mangan (Guile) 5 he ‘T pr this preparaquantities of this aenek da ri 3 cess ; Large quai muchsuccess. employed with was tion oe been dispensed in our pharmacy for a long period. /) C = -T / : oJ (rari ene, Saturday, February 7 38 DAYS PAST 327 TO COME Sunday, February 8 39 DAYS PAST Dr. Isenburg. Neckarmuende, says: August 24, 1901. ae @ Dr. F. D. Baum, Cologne, says: ‘On the ground of my experiments with Pepto-Mangan (Gude) I would recommend this preparation. It is easily taken, well tolerated without by-effects, and affords mostexcellent results.” Avot Mt at 326 TO COME “The S samples of Pepto-Mangan (Gude) which i you had the kind- ness to place at my disposal have been used with perfect success. An especially obstinate case of chlorosis, which had not been benetited by many years of treatment with iron preparations, was very favorably influenced.” f JW4A olin ery ledifePs te po Zz a Aah Act /fe ania 1/ dak Uae Yon y fj Uf f fihike Vv. ew pe Monday, February 9 49 DAYS PAST 325 TO COME [SS CREASE in the number of red blood cells as observed under the microscope after the administration of Gude’s Pepto-Mangan is a sure index of the degree of improvement in the patient's condition. This pleasant tasting compoundof organic iron and manganese causes a rapid and progressive increase in the numberof red corpuscles, and in'the per- centage of hamoglobininall cases of anzemia, chlorosis, etc., whether due to organic disease or functional disorder. Thisstatement is susceptible of ample proof, both clinical and morphological 4 A Tuesday, February 10 41 DAYS PAST ena 324 TO COME iG em y August 25, i901. Dr. Pfeffer, Czarnikau, Posen, says: ‘‘ Pepto-Mangan (Gude) was employed in the case of a verydelicate girl, six years old, both of her parents having died of tuberculosis. Since noticing the surprising increase of the bodily weight and appetite, and the beneficial effect upon the general health, from the use of this preparation in this case, I have learned to preferit ovor all other products previously employed.” a ————=—-— rs 7 Tf a 4, f , ; f Wf x BOS Wednesday, February 11 42 DAYS PAST Thursday, February 12 323 TO COME : Aug,ust 5, » 1901 LOO], i Dr. Krygowski, Lemberg, Galicia, says; is inenyrmned that 2 Sb oft en employed Pepto-Man eh et gan (Gude) ost st excellen a t resultss in var arl iou ous s for for ms of anzwmia. ao effected a com plete cure. I have also prieel ; -d Seit e Sar dur ing convalescence from other maladies poviidee co eee wate ess nd pronounced anemia. I wou ld especially cit " Ponto sep ee ee compli oe ee 3 ude) provedcating a slight albuminuria ay i ich most efficient. In general if i ante { z ; ¢ S ; eA ‘ “ . . “ae . 2 if x % an ar : 2 é 1a epto-Mangan aluable resources of therapeut (Gude) constitutes one of th abs ics.” ee ae a —= ——_—____ s 43 DAYS PAST 322 TO COME THERE IS ONLY ONE PEPTO-MANGAN. ‘*That the Medical Profession may clearly understand the situation, we respectfully call their attention to the fact that Pepto- Mangan (Gude) is not to be confounded with other preparations of iron in the formof elixirs, syrups, solutions, pills or tablets.” ‘‘Pepto-Mangan (Gude) is, a clear, dark-reddish colored neutral organic solution of iron and manganese, of an agreeable, non-astrin- vent, mildly aromatictaste ” Friday, February 13 2 44 DAYS PAST Saturday, February 14 Dr. Stadler, Singen, Baden, says: ‘‘T would respectfully inform you that since receiving sé 2 of Pepto-Mangan (tcude) I have ordered this pepsin and have dispensed completely with other iron preparations, Up 2 the present time I have found that it is well tolerated and acl ; taken, and have obtained a large numberof suec cesses,” : A Professor Weinlechner, Chief of the 5th Surgical Division of the Imperial Royal General Hospital, of Vienna, says: ‘‘ Pepto-Mangan (Gude) was tested on several anzmic patients with good results. It has the advantage over other preparations of being well taken even bychildren.” +_—— at 4 7 Sunday, February 15 46 DAYS PAST Monday, February 16 319 TO COME sa One of the most reliable preparations in this respect is Gude’s Pepto-Mangan.”’ reneei f eS Sf? Ue Peg eoET ge Hf; t ; = ; jn iming to have Fepto-Me in bulk or in ae dealer claiming to have lepto-Mangan in ; a ee of package different from that which has become familiar to the Medical Practitioner during the last twelve years is making a statement whichis absolutely false. January, 1901. Abstract from Editorial Entitled «‘An Efficient Iron Preparation,’’ Milwaukee Medical Journal. “To get the best effect of an iron preparation, it is necessary to bring it into the depreciated blood in such a formthatit is easily assimilated and all undesirable by-effects removed. 318 TO COME 47 DAYS PAST Tuesday, February 17 483 DAYS PAST 317 TO COME Extract fromClinical Report by Dr. J. W. Frieser, Vienna, Austria. “Inorganic iron, owing to its slight absorbability and assimilability, as well as its difficult digestibility and its irritating action upon the mucous membrane of the digestive tract, is not at all adapted for the rational treatmentof the forms of disease considered here and only iron of ORGANIC character which approximatesinits ecmposition to the iron present in our foods presents those advantages in improving the quality of the blood which conform most closely to the demands of a logical and successful therapy. In this connection I must refer to the view of Bunge, which nowadays is share by nearly all clinicians and pharmacologists, that iron introduced in the inorganic formis either not at all absorbed by the intact mucous membrane of the gastro-intestinal tract. or only in minimum and therefore in inadequate amounts, and hence cannot be utilized for the formation of blood.” ednesday, February 18 49 DAYS 316 TO COME Dr, J. W. Frieser—Continued. “Hence, in judging a ferruginous preparation, we must decidea the important question as to what should be the requirements ofare useful and efficient chalybeate in every directionif all demands such a to be met in a scientific and practical manner. Above all, ion and absorpt of degree high a in capable be must tion prepara and must assimilation, must be digestible, easily borne, palatable, the fenctionso! not in any manner exert disturbing by-effects upon the organisin. According to my extensive observations, these postulates are I have fulfilled in a satisfactory manner by Pepto-Mangan (Gude). had frequent opportunities, in a considerable number of cases (42) In t mywhich the preparation was employed with success, to acquain es properti al medicin al benefici andits value utic therape its with self v 50 DAYS PAST 315 To COME June 6, 1902. Dr. Eugenio Jouve, Madrid, Spain, says: ‘‘T have the pleasure to inform youthat I have used Gude’s Pepto— Mangan with very satisfactory results.” March, 1902 : : Professor Hoppe, Cologne, Germany, writes: FF at cella RLSa Thursday, February 19 Friday, February 20 51 DAYS PAST Dr. Kraus, Karisruhe, Lacen, says: ‘‘ Pepto-Mangan (Gude) was tested in my practice, and my ex- perience has since induced me to prescribe the preparation frequently. Aside from its ferruginous effect the patients praised its agreeable taste, and a prompt improvement of the appetite was , commonly observed.” fie Eee Sette sl _ “Your Pepto-Mangan (Gude) has been prescribed by me for a long time and with muchsuccess.” x) (tA ‘ es Betatte oe i «7 314 TO COMER 4 Or ‘. 7 / Ca 4 oi Saturday, February 21 52 DAYS PAST 313 TO comH August 31, 1901, Dr. Buchterkirch, Stolp, Pommerania, says: ‘‘Pepto-Mangan (Gude) was administered with excellent success to a patient who had beenunable to tolerate other chalybeate preparations, ‘The patient, who hadsuffered for a numberof years with anemia and disturbances of the gastro-intestinal functions, improved noticeably. She soon acquired an appetite; the previously existing nausea and gastric pains ceased, and the bodily weight increased, Iam, therefore, able to assert that Gude’s Pepto-Mangan Sunday, February 22 219° re a 312 TO COME 5 53 DAYS PAST 5 i Dr. Edward nal, clinical report appearing in Brooklyn Medical Jour July 1902, says: | ee Knee _ “Tn conclusion the writer would like t ) Sepa’. aading > ps ig girls e) (ud ngan o-Ma Pept cf acy ettic gic physiolo pu ae : ~ _ oo to a normal womanhood, when the crisis of — sic ee rs oe n, itio nutr wud king d-ma bloo in t defec with any ee —_ ae and pleasant, and the clinical benefits omar it is as cases ee In d. erne conc toall rent appa readily be. could s drug of ion specific as any combinat near; 311 TO COME August 7,190. Dr. Kienzle, Kaeferthal, Baden, says: ‘‘ The favorable experience which I have had in the extensive use of Gude’s Pepto-Mangan has led me to prefer it to every other ferruginous preparation.” J SA eg ae AN IR Monday, February 23 54 DAYS PAST Tuesday, February 24 310 TO COME 55 DAYS PAST “Just as Good,” ‘“‘Just the Same,” is simply a subterfuge, a figure of speech, and means nothing as applying toclinical investigation. Gude’s Pepto-Mangan is a scientific combination and sub- mitted to the Medical Profession only after the severest test both in private and hospital practice in Europeas well as in this country ites p . tt f/ ry" “/ Kins Mus ols errr Ly Oe re La oe fi D . Wednesday, February 25 56 DAYS PAST Thursday, February 26 57 DAYS PAST Dr. Narciso Vazquez, Badajoz, says: ‘‘In view of the goodresults obtained with Gude’s Pepto-Mangan I shall continue recommending it in every case in which it is indicated.” June 6, 1902. Dr. Jaime Font Monteros, Palma de Mallorca, says: “While I have not as yet collected sufficient clinical experience in regard to the value of your Gude’s Pepto-Mangan, to permit of a definite opinion, Iamable to state that its use in connection with proper diet has given me excellent results in two marked eases of ehloro-anemia with gastric dyspepsia. Friday, February 27 58 DAY PAST 307 TO COME GUDE’S PEPTO-MANGAN is the ideal ne ee test substantiate Pee eas product in the class to which it belongs—a scientific oe my submitted to the medical profession after the = rth in hospital and private practice. Clinical reports this statement. hee ee : <=> aor Saturday, February 28 59 DAYS PAST 306 TO COME ‘ June 26, 1902. Dr. Antonio Piera, Barcelona, San Gervasio, Spain, says: ‘“[T beg to inform you that whenever I have prescribed Gude’s Pepto-Manganthe results secured have.been highly satisfactory; therefore, you can count me another enthusiast. The efficacy of the preparationis rapidly manifested in cases of chlorosis and anemia,” Sunday, March 1 Monday, March 2 61 DAYS PAST se TO COME Extract ‘from “Editorial ‘Commenting.on Gude’s Pepto= pril {77, 1902. Mangan. Dr, Kovaltsik Antal, Privigyen, bahay writes: “Your Pepto- Mangan (Gude) has been employed by mein a case of acute anzmia following uterine hemorrhagxe With the most brilliant results, the cardiac palpit ation, tinnitus aurium, headache, nausea, and weakness disappearingin the course of seven days.” Ltr» 304 TO COME (From Milwaukee Medical Journal.) ' “Ready for quick absorption and rapid infusion into the cireu- lating fluid it is of certain and marked value whereit is indicated.’ ; ne 7 Wednesday, March 4 Tuesday, March 3 AVS PAST 303 ‘TO conrRr 302 TO COME 63 DAYS PAST June 14, 1902. June 17, 1002 Spain, says: Dr. Salvador VY. de Castro, Granada, Dr. M. de Saiz, Orense. says: ‘‘T have obtained excellent results fron the use of Gude’'s ; . Mangan, and, therefore, shall reco imend it to my patients.” aah Ps ce put May27, 1902 Dr. Segger Bethmann, Hanover, Germany, writes: Tan agreeably surprised at the action of onea scribed Gude’s Pepto-Mangan for two patients; disorders, the other a auiseonto alu subject to severe menstrual cases I have In both cases ia. i dyspeps ‘ i atonic i with i person shloro-angzemic n. conditio the in ement improv hea hotbedA considerable py your Pepto-Mangan (jude). which ] prefer to all modern fei ‘ugin ous preparations. 7 : Thursday, March 5 64 DAYS PAST 301 TO cOME From the ‘‘Denver Critique.’’ ‘*Therapeutic Value of Gude’s Pepto-Mangan.—A. Fasano, professor in the University of Naples, Italy, has published a very elaborate report on the newer preparations of iron and manganese and after very minute study from a chemical physio-logic and therapeutic point of view, comes to the conclusion that the only one of real merit is Gude’s Pepto-Mangan in the treatment of anemia and chlorosis.” Friday, March 6 65 DAYS PAST 300 TO COME June 15, 1902. Dr. Emilio Fernandez, Murcia, Spain, says: ‘‘T had an opportunity to use Gude’s Pepto-Manganin a case of chloro-anzmia accompanied by gasiro-intestinal disorders with most excellent results. Saturday, March 7% 66 DAYS PAST 299 TO COME April 20, 1902, Dr. G. Werner, Falkenberg, Alsace, Germany, writes; *‘T have obtained splendid results with your Pepto-Mangan (Gude) and have found that the preparation is particularly serviceable in those cases in which other iron preparations, owing to the producing of gastric disturbances, are no longer tolerat ed, or are unwil- lingly taken.” Sunday, March 8 67 DAYS PAST 298 TO COME BLOOD FOOD. El To feed the body and starve the bloodis like pouring water through a sieve. If the blood is thin and weak, the digestive power of the body is weak. Whyfeed it food that it cannot take care of ? Feed the blood with Pepto-Mangan (Gude) (iron and manganesein a pre- digested and easily assimilated form) and the whole bodyis strengthened and reorganized, and the digestive tract will promptly perform its normal function, The already weakened stomachis not compelled to do extra work; Pepto-Mangan (Gude) is immediately taken up by the blood and does not produce any gastric disturbance. —=. Monday, March 9 68 DAYS PAST 297 TO COME Cases taken from the Clinical Report of Edward C. Hill, M. D., Denver, Col., which appeared in the Brooklyn Medical Journal, July, 1902. Subject :—How to assist Young Girls to Womanhood.’’ CASE 1.—Jose K., 15 years, thin, delicate and somewhat strumous, had menstruated irregularly and intermittingly for sixteen months; erythrocytes 3,600,000, hemoglobin 58 per cent. She was takenout of school, put ona diet largely protein, given aloin, strychnin andbelladennapills for her bowels, and for her blood, Pepto-Mangan (Gude), a dessertspoonful four times daily after eating. ment she made an average weekly gain of 13¢ Underthis treat- pounds in weight, about 150,000 red cells and 314 per cent. hemoglobin, and was discharged cured in ten weeks. Tuesday, March 10 69 DAYS PAST 296 TO COME Edward C. Hill, M. D.—Continued. _ CASE 2,.—Alice R., 18 years, rather stout but ale, with greenish tinge; complained of palpitation and breathlessne ss on slight exertion; menstruation barely begun and scanty. was made to take gradual increasing exercise on her bicycle, a She cool bath every morning, less carbohydrates and more proteins in her diet, and Pepto-Mangan (Gude) in the dose above mentioned, She all her morbid symptomsin four months, and has since recovered given birth to two healthy children. Wednesday, March 11 70 DAYS PAST 295 TO COME Edward C. Hill, M. D.—Continued. CASE 3.—Amelia B., 23 years old, an overworked servant ciri, had suffered since the periodsfirst began, nine years before, with marked dysmenorrhcea, the flow being prolonged but rather scanty. The red blood cells numbered 3,800,000 per cu. m. m., with proportionate oligochromia. She was induced to rest at hcéme aud take six eggs daily, along with other nourishing food and Pepto-Mangan (Gude), a dessert spoonful four times daily an hourafter food. She made a very rapid recovery, the red ceils running up to 4,900,0vv within two months and the menstrual periods becoming quite normal, By exercising proper care she has remained well for the past eight years, 7 Thursday, March 12 a DAYS PAST 294 TO COME Edward C. Hill, M. D.—Continued. CASE 4.—Olive M., 13 years, blonde, thin, active, sensitive, a hard student, just beginning to menstruate, the flow being scanty and accompanied with pain. The blood count was 63 per cent. of norma], the color index 57 per cent. Under treatment similar to that mentioned in thefirst case, she became round and rosy, menstruated freely and easily, took on 17 pounds in weight and raised the blood findings above the normalat sea level, all within eight months, ee Zz See a/ hes G 4 Ly o/ Saturday, March 14 y, March 13 293 To pi i 1. rin, M. 1D Bre a kd D.—Continued. active, ambitious, 73 DAYS PAST 292 TO COME Edward C. Hill, M. D.—Continued. CASE 6.—Flora J., 16 years old, began to menstruate profusely a intelligent, year before, since which time she has been always ailing; erythro- J hysical examination revealed ept an wi idersized uterus. She was given cytes 3,100,000, haemoglobin 63 per cent. She was givencool baths and massage, a bitter tonic, laxatives and Gude’s Pepto-Mangan in dessertspoonful doses. When discharged cured, five months later, the blood count was 4,700,000, hemoglobin 95 percent. ng pain all ‘ough her menstrual periods for actual wastil in tablespoonful doses three times a the he lower than the hips. After 1 became quite painless, and Sunday, March 15 PAST 291 TO com#E Edward C. Hill, M. D.—Continued. f ‘lerk in a department store, was ber cent.), with a soft, systolic 290 TO COME Edward C. Hill, M. D.—Continued. CASE 8.—Nora R., 14 years, healthy in appearance but neuras- > in bed at home, fed largely on thenic ; no trouble with menstruation, except at this time she became thyroid gland, Forthis incipient exophthalmic goiter she was kept The functional murmursoon dis- and was given Pepto-Mangan(Gude) steadily for six months in des- ns of gastric ulcer ; menstrual mol- ] epto-Mangan (Gude) thri: riven |P atime. Monday, March 16 75 DAYS PAST he blood came gradually up to normal, the 1 as she gained in health, and menstruation more nervous and developed a rapid pulse and some swelling of the in bed with a cold pack over the thyroid at the menstrual period, sertspoonful doses. She has been quite well and free from the symptoms mentionedfor over a year. Ce Tuesday, March 17 76 DAYS PAST 289 TO COME BLOOD NOURISHMENT DURING LACTATION. Wednesday, March 18 "7 DAYS PAST 288 TO COME Dr. Vehmeyer, Haren, Germany, in writing on the merits of Gude’s Pepto-Mangan, says; At the time when a mother must share her food supply with her child the liability to systematic depletion is great. If the quality of the blood in the mother is allowed to fall below normal, the food of the child will not be of properlife-forming quality. Pepto-Mangan upon the direct introduction of iron and upon its power of stimu- manganese and iron. this (Gude) restores depleted conditions of the blood by feeding it with It builds rich, red blood and is a nutrient and general reconstructive tonic. Its blood-forming and in general curative properties depend both lating the appetite and digestion. Owingtoits fortunate composition preparation deserves a general symptomatic employment. Thursday, March 19 78 DAYS PAST 287 TO COME Dr. Vehmeyer, Haren, Germany.—Continued., ~ Owingto its great palatability and tole rance this preparation does not require any correctives, andis adap ted especially in obstinate and protr acted disease, in nervous, neurasthenic, and all other persons who are unable to take other iron preparations even for a short time. In people who require iron and are afflicted with ner-— vous dyspepsia Pepto-Mangan (Gud e) is not only byfar the best ferruginous preparation, but at the same time a stomachic which has a St most favorable influence upon the secr etory functions of the ymach., Friday, March 20 ay a hee , “2 DAYS PAST 286 Me Cones 4060 TO COM E Whena pon isedtp TotGaddebore eon on bale saa an ie r open é j eS Fepto-Mangan aes onion a A sata to the inde tn ati! y Gans UT oN UGudeae wait] such, The sense of taste and smell will convi nce you at once helte WAKicE intention to deceive f : reece bated as : Saturday, March 21 285 TO COME 80 DAYS PAST April 20, 1902. Dr. Mayr, Royal Counselor, Wurzburg, Bavaria, writes: “T have long employed Pepto-Mangan (Gude) in mypractice, and am much satisfied with its effect. It is well-borne by the stomach.” ae — — ——e ae Sunday, March ae 81 DAYS PAST Dr. Miguel Serrano, Murcia, Spain, ‘“‘T have tested Gude’s Pepto-Mangan in m} clinic with the most brilliant success in cases of convales« sre maladies. [t has proved to bea first-class tonic, which will meet manyindica- tions in medical practice.” Monday, March 23 82 DAYS PAST 283 TO COME August 22, 1901. Dr. E. Munk, Medical University, Maehr Neustadt, says: In ordering an iron preparation I always turn with confidence to Pepto-Mangan (Gude), since it fulfills all requirements. August 10, 1901. Dr. M. Pfaunder, Medical Instructor, Assistant Physician, Graz, says: “Within its field of indications Pepto-Mangan (Gude) has always been one of myfavorite remedies.” ae Ur . U OT \ VV : {LAr~Aw~ 4 UL dey Tuesday, March 2 83 DAYS PAST 282 TO COME July 24 Dr. C. Myhre, Sandnes, Norway, says: ‘I have employed Pepto-Mangan (Gude) in anzemie and cl conditions, and have found this preparation a most excellent one i many cases in which other ferruginous preparations were tolerated.” nesday, March 25 Thursday, March 281 ‘To mary (Philadelphia), July, 190 1, sa ht af ,aMrnanv : « re ] a vd the ellicacy of Pe pto-Mang an (Gude) in endent upon a general enloroti c cond ition. this character have responded to this ag: private practice. : oH YS PAST > See Re0th This preparation is a valuable t of ferruginous pre parations, ” ae seLeyee a : ‘redj erico Collera, City be i at fam1 paneate you verysincerelyuy obtained with Pepto-Mangan (Gude)ina cas: that you had not yielded to any other medicati o D ‘eparation will occupya place reconstruc tives.” Friday, March 27 86 DAYS PAST 279 To COME ~ August 21, 1901. Dr. Aug. Hammer, Medical Councillor; City Phys. Bathing Establishment at Langerberg, near Marienbad, Bohemia, says: “J have employed the Pepto-Mangan (Gude) ina case of marked secondary anemia with profuse gastro-intestinal hemorrhages due to an ulcer of the stomach, with most excellent results. The patient, an extremely weak woman who was somewhat disinclined to take any kind of medicine, praised within a short time the very agreeable taste of the preparation, and her appetite and condition of nutrition improved very rapidly, so that at present she exhibits a very healthy appearance. Pepto-Mangan (Gude) has been regularly continuedin her case.” According to my other experiences Iam warranted in concluding that your Pepto-Mangan, owing to its aggreeable taste and ready digestibility even in the presence of impaired gastric function, belongs to our most valuable ferruginous preparations.” A Saturday, March 28 87 DAYS PAST 278 TO COME August 18, 1901. ; Dr. Hanns Loeschnigg, Graz, Styria, writes: ‘‘Gude's Pepto-Mangan was tested in a severe case of anemia accompanied with obstinate leucorrhcea, in which I had previously exhausted the list of ferruginous preparations without success. I resorted to your product with a good deal of mental reservation, but much to my surprise it produced so marked an improvement of the general condition, with the entire dissapearance of the leucorrhoea (of course, after its administration for some time in connection with local treatment), that I must openly confess to have been unjustly sceptical in this instance. I shall always be gladto prescribe I am very glad to have found the preparation in such cases. preparations an efficient one special numberof s among the-countles whichis net a fraud.” Sunday, March 29 88 DAYS PAS‘ 277 TO COME October 1, 1902. Dr. C. G. Crumrine, Manager ‘‘ Medical Counselor,’’ Detroit, Mich., says: ‘* Allow meto state that I am still prescribing Gude’s Pepto-Mangan, and that my faith in its virtue in cases where it is indicated is growing stronger every year.” Monday, March 30 89 DAYS PAST 276 TO COME June8, 1902. Pr. Tomas Gomez de Nicolas, Toledo, Spain, says: ‘‘ While ordinarily averse to giving testimonials, I am constrained to say that Gude’s Pepto-Manganis an active and useful remedy, a tonic in neurasthenia and a good blood builder. I always prescribe it without hesitation. Wednesday, April 1 Tuesday, March 31 90 DAYS PAST z75 TO COME Dr. A. Fleischer, Hamburg, says ; ‘“\*he sample of Pepto-Mangan (Gude) sent to me some time ago was employed in acase of severe chlorosis in a poorgirl, the sister of my servant, with very satisfactory results, after Blaud’s pill, tincture of iron, and other common preparations had proved in- efficient or were not tolerated. The girl who had beenincapacitated for work for a number of months, has recovered since the administration of the Pepto-Mangan (Gude), in connection with a rational regulation of diet, to such an extent that she is able again to go in ser vice. 91 DAYS PAST 274 TO COME June, 8, 1902. F Dr. Joaquin Teixidor, Barcelona, Spain, says: ‘“‘T prescribed Gude’s Pepto-Mangan for a chlorotic young lady who suffers with intense gastralgias and frequent hemorrhages which ergot had failed to control. Under your preparation the results have been simply amazing; while the troublesome symptoms subsided the number of red corpuscles increased, as shown by the ruddy color of the face and skin of the patient. Incited by the success obtained in this case I shall continue to use the preparation wheneverit is indicated. i Friday, April 3 Thursday, April 2 92 DAYS PAST 93 DAYS PAST 273 TO COME 272 TO COME = August 19, 1901. October 29, 1901. Dr. Schwarzkopf, Pilsen, Bohemia, says: Dr. A. F. Miller,Aubu rn, N. Y., says: “I received patient has all irc ‘After having used Pepto-Mangan (Gude) in many cases of anemia, chlorosis, and irregular menstruation, I feel convinced a sample of your Pepto-Mangan (Gude) which my hout anydis bance of stomach. Previously disagree with the intestinal that your preparation is one of the best ever prescribed by me in such conditions. It is worthy of high commendation, and I pre- scribe it very frequently.” // VS y J WV Sunday, April 5 Saturday, April 4 PAST 271 TO COME October 10, 1901. Dr. F. J, Madden, Duquesne, Pa,, says: ‘‘The bottle of Pepto-Mangan (Gude) sent me was used in the case of a patient who was so much improvedafter its use that.1 decided to continue treatment. The results have been very gratifying. The function of digestion, assimilation and excretion have all greatly improved, and we nowfeel byits continued use that she may return to her former good health, for which your preparation receives my August 12, 1901 ¢ Dr. Em. Pick, Vienna, says: practice, “J have used your preparation for a number of years inmy is, neurchloros , anemia of cases in n, childre in and adults in both majority asthenia, and their sequela, with satisfactory results. The of iron on of patients preferred your preparation to other forms ient manner of account of its very agreeable taste as well as conven administration.” hearty endorsement.” J A A L 270 TO COME 95 DAYS PAST / Wf. f Tuesday, April 7 Monday, April 6 96 DAYS PAST br 97 DAYS PAST 269 TO COME July 2, 1902 , oe Dr. Hugh ug R. T hompson, Reidsville, idsvi N. C., writes: Hohl J a apthe which I used your Gude's Pepto-Mangan was one of itral inst mitral insufficiency, y; following ing anemia. anzemi TLIkeptmy kept ati patient Elixir gitali: of Digitalis Comp, Dekbut found d I I did di nott get get the desired esi result oa was much depressed. ssed. Feet Swollen, swoller urine ine high Might colored, coloncn se i eae and pati was continuously confined to the bed After usi 70 and aid One»-half aa 41 ee yr Othe bed. Aiter using two bottles ttle: of Gude’s zude's Pepto-Mangan Pe ang I ]have dischargeod. i ur sored, aaa he is nowholding the position he Formerlywoke ee vont ae Paci is due due toty é ;yourBtmost ost reliab reliable is preparation. preparatio .IToe pr i i always prescribe it 268 TO COME Dr, Leopoid Eglseer, District Phys ician, Obernberg, a iS. Upper Austria says: “Tt affords me especial satisfaction to express my plea ure regard- ing the excellent eifect of Pepto-Mangan (Gude). 1 have employed this preparation repeatedly with great success, Therapid and marked improvement of the appetite in anemic patients, as well as the improvement in the general condition, was most surprising. 1 intend to continue the further use of your valuable remedy with the greatest confidence, and remain with an expression of my highest esteem.” Wednesday, April 8 98 DAYS PAST 267 TO COME Thursday, April 9 99 DAYS PAST 266 TO COME October26, 1901. June 25, 1902. Dr. Jose Estell, Malaga, says: “The rational combination and careful manufacture of PeptoMangan‘Gude; are a guarantee of its effect. You are atliberty to cite me as an enthusiastic admirer of your preparation.” Dr. S, Shaham, Philadelphia, Pa., writes; ‘“‘Pepto-Mangan is a very excellent preparation in cases where it is indicated. The bottle you sent meI used for myself. I intendto continue to prescribe as I feel that it did me a great deal of good. 4/4( Friday, April 10 100 DAYS PAST 265 TO COME October22, 1901. Saturday; April11 101 Days PAST John E, Purdon, A. B., M. D., Stockton, Cal., says: ‘“T have used Pepto-Mangan (Gude) repeatedly and think highly of its blood-makingpowers in the case of young children who have suifered from the blood deteriorating influence of malaria. When an experienced physician uses a medicine in his own family it is to be presumed that it is producing good effect. Pepto-Mangan (Gude) for I have to thank the restoration to health of mylittle granddaughter, aged 4 years, who was suffering from the effects ef a residence in a malarious part of the Indian Territory. I also prescribed it for her mother with goodresults. a “If mothers would learn to studythe color of their children’s ears against the light before, and a monthafter usingthe ‘‘Gude’s,” they would soon knowits value.” 264 TO COME June 10, 1901. Dr. A. Stewart, Glasgow, writes: ‘‘ Through your kindness I received through Messrs. Robert & Co., of London, a supply of Gude’s Pepto-Mangan. My patient, who is about 72 years old, has used these samples, and it affords me much satisfaction to inform you that she states that she has deriveda re- markably@beneficial effect from the same. I thank you for your courtesy a.d offer of further samples, but I do not think this necess- ary, as I have already arrived at a decision, and do not hesitate to say that Pepto-Mangan (Gude) is an excellent preparation andis well adapted to support and invigorate weak persons. It will afford me muchpleasure to recommend the preparation to my patients..” sunday, April 12 102 DAYS PAST 263 TO COME August 17, 1901. Dr. D. Hirsch, Krakau, Galicia, says: ‘‘ At the time I requested a sample of Pepto-Mangan (Gude) your preparation was not newto me, sinceI had often previously usedit with excellent success, especially in anzemia of women and children. When, therefore, I desired an iron preparation for my own family I was led to request you for samples, and I am much pleasedtoin- form you that its taste was muchrelished. My twochildren (one and one-half and two and one-half respectively) took it so eagerly in milk that they would scarcely take any milk which did not contain it. No by-effects of any kind occurred which damanded a discontinuance of the preparation. In brief, it was well tolerated and acted splendidly.” Monday, April 13 103 DAYS PAST 262 TO COME June 16, 1902. Dr. Francisco Reig Pastor, Valencia, Spain, writes: “In viewof the results obtained from Pepto-Mangan (Gude), in my practice I considerit most useiul in those cases in which the patient finds it difficult to take a sufficient amount of nourishing food for his maintenance. On the other hand byreason of the considerable quantity of iron and manganese it contains it becomes a powerful tonic in those cases of primaryor secondary anzemia in which it is necessary to stimulate the nervous system and to improve the blood and assimilation.” ZZ Tuesday, April 14 Reo en Dr. a: Ross, = eeeeae ditor of Maritime Medical News, Halifax, Wednesday, April 15 105 DAYS PAST N. S., writes: 260 TO COME August 12,1901. “The writer has used Pepto-Mangan (Gude) considerably and can testify to its beneficial effects in the great majority of cases in which it was indicated.” Dr. Drzycimiski, Osche, W. Prussia, says: ““T have tested the Pepto-Mangan (Gude) and obtained very satisfactory results in a case in which nervous syptoms were par) } ticularly marked, while other iron preparations proved ineffective.” Thursday, April 16 106 DAYS PAST 259 TO COME August 7, 1901. Fridav, April 17 107 DAYS PAST 258 TO COME June 7, 1902, Dr. Fritz Thelemann, Surgeon-General, Coburg, writes: Dr. Jose Yanez, Sevilla, Spain, says: ‘‘Pepto-Mangan(Gude) acted extremely well inall cases in whichit was employed. In the case of my patient, who has suffered for a long time with neurasthenia in consequence of anaemia, a prompt I will continue to recomand visible improvement ensued. mend and employ Pepto-Mangan (Gude) in the future in appropriate “T am well satisfied with the results obtained in my clinic with Gude’s Pepto-Mangan. It is sufficient to observe the logical combination of its ingredients and the painstaking mannerin whichthis is effected to predict the best results from its use in those ailments in which such a preparation is indicated.” Cases. Sunday, April 19 256 TO COME 9 DAYS PAST TO COME November26, 1901 Dr. A. H. Smelthurst, Philadelphia, Pa., says: ‘‘With my experience of four years, I can truly say that Gude’s Pepto-Mangan has not failed me in one instance where indicated, and I havetruly tested it in chlorosis where the patient wasfailing fast and her parents had little hope of her recovery. Not only this but other cases can I call to memory which have been benefitted by PEPTO-MANGAN (GUDE) rapidly and easily assimilated. Produces a rapid increase of red orpuscles in the blood ; is perfectly miscible with sherry, milk or ter; pleasant and agreeable to the taste; gives appetite and the system ; children take it readily, it can also be adminised to infants. Does not affect the teeth. es he Ry Does not constipate or ‘ produce gastric turbance. are caeae P Monday, April 20 255 TO COME 110 DAYS PAST Tuesday, April 21 Angust 10, 1901. November30, 1901. M. A. B. Smith, Prof. of Applied Therapeutics and Class Instructor on Practical Medicine, Halifax Tedical Col- lege, Halifax, N. S., says; “About four years ago I treated three cases of anemia with a view to testing the value of Pepto Mangan (Gude) as compared with other preparations of iron. After employing Blaud’s Pills and other inorganic preparations, I gave to f hree patients a dozen bottles of Pepto-Mangan (Gude), using at the sametime the heemoglobinometer and hemocytometer, to estimatethe effect. These instruments of precision showed a marked improvement in the blood beyond results observed from the other forms of iron. Since then I have employed it very largely both in private practice andat the Victoria General Hospital, and mybelief in its superiority over other preparations in the treatment of simple anzemiahas been fully con- firmed. I conclude this is due to the iron being an organic prepar- ation, com ined as a peptonate in a readily assimilated form; and also to the manganese which it contains and which it supplies to the 254 TO COME 111 DAYS PAST Dr. Koenig, Wiesbaden, says: “T+ affords me muchpleasure to report to you the very satisfactory effect with your Pepto-Mangan (Gude). I employed it in two the cases of obstinate chlorosis of several months’ duration, and in severe a after cent convales was which case of two children, one of attack of influenza, while the other was in a condition of general in thefirst weakness of rachitic origin. In all thesecases, especially an exnamed(chlorosis and convalescence), the preparation exerted stimuin action its instance every in while e, influenc cellent tonic the In evident. ly distinct was n lating the appetite and digestio return regular and prompt a with ensued recovery rapid a case first of the menses. which had been absent for many months. results, I amvery gladto iriform you of these very satisfactory which ion, preparat this of use the continue and I shall in the future te, and is so worthy of recommendation as an agreeable chalybea which promotes an increase of stréngth and assimilation.” __ 4 __ = ee 7 4 4 f A Wednesday, April 22 112 DAYS PAST 253 TO COME December5, 1901. Dr, Rayneri, Havana, Cuba, says: “T have prescribed Gude’s Pepto-Mangan frequently, and have found it a good preparation, onethat produces effective results with- out distressing the stomach.” Thursday, April 23 113 Days PAST 252 TO COME Taney 0 1 Dr. H. I. Roberts, Wellsburg, W. Va., says: “T have tried Gude’s Pepto-Manganin the case of a member of myfamily, and have found it all youclaim. In fact it surpasses myexpectations.” Va Saturday, April 25 Friday, April 24 114 Days PAST 250 TO COME 115 DAYS PAST 251 TO COME August 28, December 380, L901. Dr. Mare Eckstein, Vienna, says: Dr. W. R. Romine, Pineville, Mo., writes: ‘Ag to the outcome of my observations with Pepto-Mangan (Gude), I would inform you that I have derived most satisfactory results “T am pleased with Pepto-Mangan (Gude) because in my hands it has given better results than any remedyof its kind I have ever used. For anemia and all wasting diseases, it is a valuable remedy. I believe Pepto-Mangan (Gude) to be the best compound of iron and manganese extant to-day. In all casess where iron is indi- from this excellent preparation in chlorosis and anzmia, in nervous dyspepsia, andin all diseases caused by a poorcondition of the blood. I therefore prescribe this preparation gladly and frequentlr, and have often said a good word for it amonz my colleagues.” cated Gude’s Pepto-Mangan has given me better results than any other drug or chemical. In some cases of female trouble it has proved itself & perfect Godsend.” 4 0/ k Lf Ox Lt 12 get PET ; J) Le 117 DAYS ROSA: Soran Sunday, April 26 HM Dr. Telesf J elestoro Gonzalez : PALA alez, Avila, says: n; d 2Pepto-Maangan (Gude) ina case of anzemia, with “After prescribing Pepto-Mangan (Gude) for a numberofyears disturbed 2 andae of appetite, and although the patient has not yé ti 1 he feefe : is the more gr:atify relieved. eatly nee he ia been sic ‘Kki Tor some time andThis is sixty years old,’ —————— f / / / Dr. Trainer, Freiendiez b. Diez a/dAe June 5, 1902, | have become convinced that this prepareation is the best and most reliable chalybeate. the Even in conditions of con ipleteeexhaustion of digestive functions it may be employed with constant success, nd is much relished. Hence it is my cl istom to b or der only this pre*ind naration, and to to recommend 1t where ——_,—— = = Thursday, April 30 120 DAYS PAST W. J. Sullivan, Baltimore, Md., says: “Tn regard to the results obtained from using the original bottle of Pepto- Mangan (Gude) sent me, I desire to testify to the merits of the preparation. The patient to whom I gave the Pepto-Mangan (Gude) was suffering from anzmia and irregularity in menstruation. At the present time, after taking the greater part of the bottle, marked improvementcan be noted, especially in regard to general health. 244 TO COME Substitution upon Physicians’ Prescriptions is a crime of the basest order. Not one alone against the integrity of the physician, but committed after thought and deliberation against the helpless, sick and dying. ‘ If cheapness is most desired, commercial combinations placed upon the market for substitution, can be procured to take the place of an original product. Such bear no evidence of having stood the test of searching investigation. Salesmanship does its part—the *¢ Just as Good,” ‘‘ Just the Same” argument is not intended for any purpose other thanprofit. Will continue to use Pepto-Mangan (Gude) until full benefits are realized. f 121 DAYS PAST 245 TO COME April 23, 1902, Dr Friday, May 1 jy Saturday, May 2 122 DAYS PAST Sunday, May 3 243 TO COME Dr. I. P. Alger, Coldwater., Mich., says: “Allow me to say that your preparation, where such medication is demanded, operates remarkably, by rendering non-active the metabolistic forces of the intestines, and seems to be readily assimilated, increasing the powerof digestion. It has no superior in Dr. Fernando Tames, San Sebastian, says: ‘‘Gude’s Pepto-Mangan gave excellent results in the first case in which it was prescribed by me, and since then I have recommended in several other cases of exhaustion and debility following long- stauding diseases.” Monday, May 4 124 DAYS PAST 241 TO COME 240 TO COME Dr. C. O. Dunlap, McArthur, Ohio., reports: April 3, 1902. “One case in particular in which the remedy was used -and in which theresults were perfectlysatisfactory. Miss——— aged 17 years, had never menstruated, was anzemic and had aconstant dry cough. Auscultation showed hemiec murmurs. After six months use of Pepto-Mangan (Gude) she had gained in weight, her color freshened up and she began to menstruate regularly. This was in 1899 and sheis now20 years old, and at that time she weighed 65 pounds, and two weeks ago, when I last saw her, she weighed 115 pounds. During a portion of the time-in which I treated her, I gave her strychnia sulphate, but Gude’s PeptoMangan wasthe main reliance.” Dr, Oesterreicher, Vienna, Austria, writes: ‘‘T have been exceedingly satisfied with your Pepto-Mangan (Gude), which I have employed almost exclusively in pediatric practice. Inall anzmic conditions of debility, whether resulting from malnutrition or following recent recovery from severe diseases; in short, in all conditions in which a ferruginous preparation is indicated and in which there is an impairment of the digestion, I have been able to note decidedly favorable effects after a comparatively brief period of administration, to which the ready digestibility and agreeable taste of the preparation materially contributed.” DELIpf t a) cw 04 Cac aie Me 7 \ 4 oe IK J _} A ry —7 Wednesday, May 6 126 239 TO COME DAYS PAST May28, 1902. Dr. Tamke, Medical Counselor, Aurich, writes: ‘‘T have keen well satisfied with the results obtained from your E > ent 4 vt o-Mangan (Gude), and make use of it in all cases in which I v egard the udministration of iron as indicated.” > March 6, 1902. Dr. Juiius Silberstein, Department of Interior, U. S. Indian Service, Yainax, Oregon, writes: “T have used Gude’s Pepto-Mangs un the future.” 4 Ps 1] it now, and will use it in Thursday, May 7 127° DAYS PAST 238 FO COME May 20, 1602. Dr. F. Seidenglanz, Wienerherberg, Austria, writes: ‘“‘T have tested your Pepto-Mangan (Gude) in a case of a chlorotic girl, [4 years old, and since using the preparation the patient has markedly improved not only from a subjective but objective point of view. There has been not only a considerable increase of the bodily weight but also an increase of the vascular tone, as can be noted by the markedly augmented supply of blood to the visible mucous membranes. I must regard your Pepto-Mangan (Gude) as an excellent preparation which deserves to be tested in all eases of aneemia and chlorosis.” Saturday, May 9 Friday, May 8 128 DAYS PAST 129 DAYS PAST 236 TO COME 237 TO COME May 5, 1 992. April 10, 1902, Dr. Weiner David, Tata-Tovaros, Hungary, writes: ‘ ‘I have prescribed your Pepto-Mangan (Gude) in a case of exhaustion following a severe attack of scarlatina in a man 32 years old. He was very anaemic, and both feet were swollen at night al- though there was no nephritis. After using your preparation he was completely restored to health in the course of two weeks. Ha regained his ruddy color; the feet no longer became swollen , and he is able to walk from morning until night withou t getting tired.” H. J, Shatto, M. D., Akron, 0O., says: ‘“The sample bottle of Pepto-Mangan (Gude) that yeu sent me in July was used in a case where nearly all preparations of iron had been tried until patient and family declared that iron could not be tolerated. I then gave Pepto-Mangan (Gude) and the preparation was so agreeable no trouble followed. The result could ask and more than i expected. It has becom was al] that IJ e my favorite remedyin all conditions of great debility calling for iron.” OT” fp me 4 Qf ry. le Sunday, May 10 130 DAYS PAST Monday, May 11 235 TO COME 131 DAYS PAST April 8, 1902, Dr, Leop. Wappner, Vienna, Austria, writes : “Your Pepto-Mangan (Gude) has been number of cases, and 1 am much pleased best effects were obtained in chlorotic girls become anzemic owingto protracted uterine 234 TO COM August 15, 2402 Dr. W. B. Heagerty, Minneapolis, Minn., says : used by me in alarge with the results. The and in women who had disease,” “I have used your sample of Gude’s Pepto with excellent results, there being no gastricirr -Mangan on a patient itation or constipation cause d while it was being administered. all cases when iron is indicated.” — fj ane en — I am prescribing it in i Tuesday, May 12 132 DAYS PAST 233 TO COME April 15, 1902. Dr. Stern, Freiburg i. B. Germany, writes: “T would assure you that among the numerous iron preparations existing at the present time I always give your Pepto-Mangan the preference. Your preparation requires no advertising; it advertises 133 Wednesday, May 13 DAYS PAST 232 TO COME August 19, 1902. Dr, John Walker Fairing, Springfield, Mas s., says: “‘Gude’s Pepto-Mangan is giving mark anemia in the case of a memberof my ed results in persistent family. It is the only ferruginous tonic exhibited in the case and which frontal headache,” does net pr a peti Friday, May 15 Thursday, May 14 134 DAYS PAST § GUDE § PEPTObee Vi 4 231 TO COME Is the STANDARD in the class to which it belongs. Is rapidly and easily assimilated. Producesa rapid increase of red corpuscles in the blood. Is perfectly miscible with sherry, milk or water. Pleasant and agreeable to taste. Gives appetite and tones the system. Children like to take it, and it can even be given to infants. DOES NOT AFFECT THE TEETH. Does not Constipate or Produce Gastric Disturbance. J > J “CH at f \ 135 DAYS PAST Dr. S. Reti, 230 TO COME May31, 1902. Specialist for Sexual Diseases, Vienna, Austria, writes: ‘None of the ferruginous preparations employed by me in my extensive practice is so willingly taken as your Pepto-Mangan (Gude). In all conditions in which it is desirable to furnish iron to the organism and also to stimulate a more active metabolism, 1 prescribe your preparation, whichin a comparatively short time promotes the appetite and digestion and improves the general appearance. The patients were never tired of praising the agreeable taste of the medicament. In my practice I usesit particularly in cases of nervous overtaxation and in conditions of general weakness,” Saturday, May 16 136 DAYS PAST 229 To COME Sunday, May 17 137 DAYS PAST 228 TO COME April 10, 1902. Dr, Leidholdt, Halle, a/S., Germany, writes: ‘*T am extremely well satisfied with your Pepto-Mangan (Gude).”’ Dr. L. Cattori, Locarno Meuralto, writes: ‘‘T have derived good effects from the use of your blood-builder Pepto-Mangan (Gude), and encourage its use among mypatients,” { A April 20, 1902. Dr. Julius Wellisz, Homolicz, Hungary, writes: “T employed your Pepto-Mangan (Gude) in the case of a chlorotic girl, 15 years old, with extremely poor digestion, general weakness, headache, etc. After using about twobottles the patient had visibly improved. No untowardeffects have been observed. I have rarely made use of so excellent a preparation. In a word, you deserve full full praise and recognition for your happy combination.” o / Monday, May 18 PAS 227 TO COME August 7, 1901. Dr. Pauli Kelier, Erfurt, writes: Respecting Pepto-Mangan (Gude), I would infor m you that I have been well satisfied with its action in all cases in my practice The patients willingly took the preparation on account of its agreeable taste. Unpleasant after-effects uponthe stomach, oras regards the teeth, were not observed in a single instan use produced in a short time a considerable ce. In all cases its improvement of. the appetite, and an increase of strength as well as a better appearance of the patients. Anzmic patients were especi ally grateful for the rapid disappearance of the headaches, so that in these cases I frequently prescribed the pr ation.” Tuesday, May 19 139 DAYS PAST 226 TO COME September 15, 1902, HarryA. Hill, M1. D., Brooklyn, N. Y., says: ‘*T would state that I prescribed your Pepto-Mangan (Gude) to a patient whom I operated upon for hemorrhoids, and as a result of this she lost quite a great deal of blood. She was somewhat aneemic prior to the operation. Linstantly placed her upon PeptoMangan (Gude). Very shortly her conjunctivae began to assume a rosy tint, and her lips became more normal andshe lost the pallor of the face which is invariably characteristic of such cases of anemias. I told her to procure (by prescription) some more of your preparation, and am glad to state that she is well as ever. This is one of manycases which has thrived on yourpreparation, Wednesday, May 20 14C DAYS PAST Dr. H. L. Frost, Prof. of Surgery and Clini cal Surgery Cleveland Homeopathic [Medical College, says : ‘‘ For several years I have used Gude’s Pepto -Mangan very extensively in myprivate practice, as I have found it far superior to all preparations of a similar nature for all general anemic conA> ditions.” pE ae a Ne 141 DAYS PAST 224 TO COME 225 TO COME Cleveland, Ohio, September 11, 1902 ©me U Thursday, May 2 August 13, 1901. Dr. H. Krassnig, City Physician, Opponitz, Lower Austria, says: “I have much satisfaction in informing you that I have prescribed your Pepto-Mangan (Gude) for many years as a restorative in anemia, neurasthenia, and in conditions of weakness of all kinds, and have always derived the most excellent results from its use, Friday, May 22 142 DAYS PAST 223 TO COME Dr. C. C. Brice, Editor Southern Clinic (Sept. issue 1902), says: “GUDE'S PEPTO-MANGAN.—Thereis no ‘just as good’ as the above. Don’t let the substitutor with horns on him rob you before your face. If you wantthepale, half dead, anemic convalescent to brace up. get red in the face with good red blood in him—be sure you give him Gude’s Pepto-Mangan.” ee eas. ] rt Saturday, May 23 143 DAYS PAST August 12, 1901. Dr. Adolf Kranz, Vienna, says: ‘‘ As regards the therapeutic value of your Pepto-Mangan (Gude) I amof the opinion that it is the best among all iron preparations. It has given excellent service not only in the lighter degrees of chlorosis and anzemia, but also in the sever e forms. The preparatien was gladly taken by all mypatients, witho ut producines disturbances of any kind.” Sunday, May 24 144 DAYS PAST Monday, May 25 221 TO COME September 6, 1902. Dr. Geo. F. Thomas, Lowell, Mass., says: “This is to certify that | have used Pepto-Mangan (Gude) wherever it was indicated, and I must say that I have found the greatest benefit in the greatest numberof cases of any of the iron preparations that I ever used.” 145 DAYS PAST 220 TO COME April 10, 1902. Dr. Emil Schantz, Berlin, Germany, write s: “You _ / r Pepto our. Pepto-Mang Mang:an (Gude)) hashas b been partic i ularly employed by pine : hildren, being gladly taken and well tolerated. at selina ae ie appetite and appears to increase the strength of the little JE 2 Set f y i Wednesday, May 27 Tuesday, May 26 146 DAYS PAST 219 To COME 147 DAYS PAST July 3rd 1902. Dr. Wm. [t. Cadwell, Providence, R. I,, writes: ‘“T have used Pepto-Mangan (Gude) in a numberof eee anemia. chlorosis and general debility, and consider hea eat ey of all the Iron preparations, and shall continue toprescribe 1t In my practice whereverI find an indicationforits use. May1, 1902, Dr. Simon Budai, Budapest, Hungary, writes: ‘‘] made use of your Pepto-Mangan (Gude) in cases of anzmi cachectic patients. The results were strikingly good, especia c and llyin those cases in which other iron preparations proved ineffic ient.” j Tommy, 218 TO COME Thursday, May 28 148 DAYS PAST 217 TO COME November 25, 1901. Dr. W. Wildman, Phila., Pa,, says: ‘‘T have given your Pepto-Mangan (Gude) atrialand it certainly has helped the patient who respondedto its action ina very fewdays. Shall continue to recommendit.’ Friday, May 29 149 DAYS PAST 216 TO COME May6, 1902. Dr. S. Von Velzen, Joachimsthal, Germany, writes: “T have derived most exceHent results from Pepto-Mangan (Gude) in chlorosis, anaemia, etc. Your preparation seems to be the best remedy up to date in the treatment of chlorosis.” Saturday, May 30 215 TO COME 150 DAYS PAST ahci 214 TO COME August 14, 1901, Dr. Hofmeister, Cuestrin, says: “T, hereby inform you that I am well satisfied with Pepto-Mangan (Gude), whichis well worthyof thefirst place among the many iron preparations, especially since it does not affect the teeth in any manner,” Sunday, May 31 151 DAYS PAST Sit LW August 20, 1901. Dr. J. Kux, City Physician, Littau, says: ‘I take this opportunity to inform you that I have employed Pepto-Mangan (Gude) with brilliant results in the case of a woman, 32 years old, who had been much exhausted by excessive menstrual hemorrhages for a numberof years.” Pzie ML. ? LY q Ape ot, a Vi 7A, ) Tuesday, June 2 Monday, June 1 152 DAYS PAST 153 DAYS PAST 213 To comE Dr. C. H, Wallace, St, Joseph, Mo., says: ‘*T am a constant and almost daily prescriber of your (Gude’s) Pepto-Mangan and have beenforthe past three or four years. I do not know howI can give it any higher commen dation than the above,” yp To ay as aaa > AG AI An U AD f Dr. L. Catenarri, Cadro, writes: ‘“‘T have the honor to inform you that your blood-builder Pepto- Mangan (Gude has always given me the best results in various conditions of depression andin convalescence.” Wednesday, June 3 154 DAYS PAST 211 TO COME Thursday, June 4 155 DAYS PAST 210 To Come H. T. Wolff, M. D., Yonkers, N. Y., says: August 1901, Dr. Julius Keppel, Rovereto, Tyrol, Austria, says: ‘The sample of your preparation, Gude’s Pepto—Mangan, sent me some time ago was given a fair and impartial trial and found to be all thatit is represented—agood general tonic and ‘“‘bloodbuilder”. ‘During the last two years I have constantly and extensively employed Pepto-Mangan (Gude) in mypractice, and cannot suffici- effect.” digestive organs.” I have since used it in all conditions, where indicated, with happy ently praise its curative action in diseases of thge-nervous system and a } f}s fi Yiu f aa Y } a y A tFA= = f t TA Friday, June 5 156 DAYS PAST 209 TO COME Dr. G. Kimmig, Bad Petersthal, Schwarzwald, Says: ‘“‘T used Pepto-Mangan (Gude) last spring in the case of a patient who hadsuffered for a number of months with chronic gastro-intestinal catarrh and severe diarrhoea, and had been perceptibly reduced in strength and weight. The result was very encouraging, and since then the preparation has been continued andthe patient hes distinctly improved. The expectations of a comple te cure of her trouble are very good. In my opinion this preparation is a very commendable remedy in all conditions of weakness, because it is so readily digested and so well tolerated,” Saturday, June 6 157 DAYS PAST 208 TO COME ~ August 8, 1901. Dr. Knitel, Ebelsberg, Austria, says: ‘In respect to the curative properties of Gude’s Pepto-Mangan , I have been particularly satisfied in the treatment of anzmi a and chlorosis. In only one instance was there a complaint concerning someslight difficulty in digestion. Especially good results were obtained in a demented patient who took but very little nouris hment, and it is my opinion that this patient is indebted to PeptoMangan which she has takenfor the last six months, for being still able , to walk.’ Monday, June 8 Sunday, June 7 PAST 159 DAYS PAST July Dr. C. D. Dunlap, McArthur, Ohio, says: ‘* As to Gude’s Pepto-Mangan, it does not need any word of en- comium of mine—results speak for it.~ Ihave been prescribingi t for several years and have not been disappointed. I had aease in which Pepto-Mangan was the principal remedy exhibited and the results were as pleasantly surprising to the patient’s friends and to the patient herself as they were to me.” 2U6 TO COME April 10, 1902. Dr, Max Kober, Beuthen O. Schl, Germany, writes : ‘‘T have prescribed your Pepto-Mangan(Gude) in a severe case of a neuropathic and very anzmic young girl, with the best Besides an increase of strength and of the bodily weightsuccess, and a better color of the face, menstruation, which had been absent for about a year, returned underthe useof this medicament.” /} Tuesday, June 9 160 DAYS PAST Wednesday, June 10 ia 161 DAYS PAST 205 To COME Dr. Hermann Metall, Vienna, Austria. : : Ae tad : 2 From clinical re- Austria, January, 1902. ‘‘ Altogether, twenty-three cases of anemia were treated with Pepto-Mangan (Gude), of which twelve show globin per cent. of the blood after fourteen ed & normal hemodays, five after three weeks, and five after a month. On the other hand. one of the patients who had hereditary trouble (her fathe r having cvttered from pulmonarydisease), was disch dition of the system. The ness — weakness ees from systemic derangement, usuallyfaint Ox the blood supply. The Patient as weak,listless and over come by theleast exertion, «A “sufferer from heart trouble ae the usual verdict by y and friends. W uere no organic lesion is found, the famil faint ing spells may be combated by treating the arged only improved, the blood, after two months’ treatment with Pepto-Ma ngan (Gude), showing only an ea ae of the Sea by iCpie ey Pecos He ato ication vy strengthening the system. Dizzi the weakness Sephy Js ane increase of globin 75 per cent. This was probably a case of tuberculosishemo which simulto ated an obstinate or severe chlorosis at its beginning. f ness and fainting spells generally cease as the patient gains in strengtha ndhealth, ; In cases of fainting and debility Pept o-Mangan (Gude) is wf ; i 204 TO COME “eotan ¢ aieNone AND sahtes sities Gave may arise Irom cardi ac diseases, such as ericarditi s, Cardiac Dilatation, Acute or Chronic Myocarditi the Fatty Heart, Cardiac Palpitation and Bradycardia, or from as,gener ally debilitated con- : port published in Medicinisc h-Chirurgisc hes CentralBlatt, Vienna, : ARONti I ee prompt in result as a general tonic and recon structor,. It is an ideal compound for combating weakness and wasting conditions. It increases the appetite, gives tone to the system, and acts as a ; general reconstructive a gent. oie rere Udo es li» pe — he , f va he ees, } Y UO a VA D Ee Tip= p f h tA < J W374 Oo it AL Died en serra | fe hiToe ary hn ala Ny : j AP 7 * iz ~ ———_—/ Thursday, June 11 162 DAYS PAST 203 TO COME From the published report of cases treated by Dr. Enrique : a ° Dingo, ; Spt. Hospital No. 1, Hava Cuba, Dr. Jose F, Benitez, Chief of the Laboratory, na, Picroscopist. ( ASE i. N. G., aged 28, sub mits to treatment, suffering from lack of nourishment, emaciation, with skin and mucous membra extremely pale, great loss of Strength, with memory impaired nes , suf‘eringIrom agrypnia and anor exia, with all the signs ofa pro een ts consequent to a chro nic malarial infection to w hich found he had FeploMangan (Gute) was acimibiaesy deity fh gM conation the dose ; s5 at bre breakfasst t and ar dinne ler tin = ee ne y _ two tablespo ls count of blood—2,400,000 red time, with simply quinia wine. onfu First corpuscles, having used Tho ma Zeiss Friday, June 12 163 DAYS PAST 202 To COME Dr. ee oe? nee hemocytometer; ten days after the commencement of fee the treat ment, ties patient, so ciel pale before, began to recover the redcolor of the checks, and his general condition was so satisfac tory that he delighted in acknowledging how well he was feeling since taking the new remedy, having increased 5 lbs., in those ten days , and being able to move from one end of the ward to the other with out the impediment he felt at the beginning of the treatmen t. His blood was examined a second time showing an increase of 300,008 red corpuscles. This patient was discharged fully recovere fifty d days after taking the treatment, weighing 130 pounds and with s blood count of 2,800,000 red corpuscles, Ca of 7} £ LUG Saturday, June 13 Sunday, June 14 201 TO COME Dr, Enrique Diago, Havana,—Continued. CASE 2,—Mrs. C. D., aged 34; having had miscarriage, submit ted to treatment to remedy the symptoms of anemia consequent to said accident, and which manifest themselves by emaciation, the yellow- ish color of the skin, loss of strength and gastric disorders, This patient only weighed 99 Ibs. on entering the hospital; her blood showed a marked decrease of hemoglobin with only 2,800,000 red -orpuscles; ten days after treatment she felt so improved that, per1aps with the idea of attaining a more rapid cure, she went so far as to take five tablespoonfuls of Pepto-Mangan a day, causing a A G ¢; f fot irads L fp Php att AHehiy 1 — Freon Avy EO 165 DAYS PAST 200 TO COME Dr. Enrique Diago, Havana.—Case2, Continued. disorder of the stomach. The administration of the remedy had to be stoppedfor five days, and to cure her of the disorder she was given a purgative and some tablets of bismuth and salol. The stom ach having recoveredits normal functions the Pepto-Mangan (Gude) was again administered, first in two teaspoonfuls doses, and three days after two tablespoonfuls. She recovered entirely without any further mishap. On leaving the hospital, the hemoglobin was normal, the count of her blood showed 3,500,000 red corpuscles andher weight had increased 21 Ibs. in 50 days of treatment DA ba Ege hgee ince de A i { A —~ I~ We { A Ht J, @ 4 tA y v7 tytL 1) Te ce ae C AeA 3 W) Monday, June 15 166 DAYS PAST 199 To COME Dr. Enrique Diago, Havana.—Continued. CASE 3.—Mr. M. D., aged 26, had suffered during the last month of December fromanattack of acute poli-articular rheumatism, and submitted to doctor's observation showed pale teguments, fatigue from walking, extreme emaciation, perimalléeolar edema, but without valvular lesions, absence of appetite andof sleep, functional disorder s of the genital apparatus, dyspepsia, and weighing only 92]bs, His blood was examined revealing a decrease of hemoglobin and only 2,500,000 red corpuscles. After 15 days of treatment, which consist— ed of two tablespoonsfuls of Pepto-Mangan (Gude) at breakfa st and dinner time during the first 15 days, and of an additional spoonful after at noon time, he had gained muchin strength, the paleness had almost disappeared, the hemoglobin had increased and reachedits normal condition, the red corpuscles had also increased to 3,200,000 and he was discharged fully recovered forty days after entering the hospital. / Tuesday, June 16 167 DAYS PAST 198 To COME Dr. Enrique Diago, Havana,—Continued. CASE 4.—Mr. R. G., aged 42, without diathesis and without any organic lesion, applied to this hospital in a very alarmed state of mind because heis subject to frequent attacks of vertigo, palpitations, extreme weakness, muscular erratic pains, He acknowledged to have suffered recently an attack of the la grippe, during which his nervous troubles became severe, the fever was not very intense, the air passages were hardly affected, he suffered severe muscular pains of the neck, of the loins, and alsoperiarticular pains, cramps andintense cephalalgia. The examinationof his blood re— vealed the presence of 3,000,000 red corpuscles, his decreased weight only reached 110 lbs. He was put exclusively under Pepto-Mangan (Gude) treatment; twenty days after the pains had ceased, he o well, his weight increased four pounds, and the red padae 200,000. He was discharged thirty days after entering the hospita entirely recovered. Wednesday, June i7 168 DAYS PAST 197 TO COME Dr. Enrique Diago, Havana.—Continued. CASE 5.—Miss C. P., aged 16, her color was very pale, with very scanty muscular and adipose developement, menstrual and nervous disorders, her physical growth was not in harmony with herhygienic regime, which had been neglected. On examination she showed the morbid association of the nervous and dyscrasic element s which in this country constitute the endemic type of the chloroa nzemic patients, Her weight was only87 lbs., and the count showed 1,800,000 red corpuscles. After ten days of treatment, there was an increase of 200,000 corpuscles and 3 pounds in her weight. This patient was taken awayfrumthe hospital by her relatives on the 26th da y from entering , and her weight had increased 4 lbs. more, makinga total increase of 7 pounds. Thursday, June 18 169 DAYS PAST 196 To COME Dr, Enrique Diago, Havana,—Continued. CASE 6.—Mr. G. F., aged 36, without any diathesic record and not having recently suffered any severe illness, he had noticed a weaking of his strength, a decrese in his normal weight, extraordinaryfatigue fromhis usual work, and attributes his condition to the transgression of hygienic rules, First count showed 2,600,000 red corpuscles andhis weight 106 lbs. Put under treatment with Gudes Pepto-Mangan, he was discharged, at his request, thirty-six days after having increased in weight 11 lbs., a second count showed an increase of 250,000 red corpuscles. Heresorted to his usual occu- pations without experiencing anyfatigue. Friday, June 19 170 DAYS PAST PERINEAL PROSTATECTO/SIY Saturday, June 2 195 TO COME is an operation which is founded on sound anatomical principles. The posterior portion of the prostatic urethra is removed, thus allowing easy access to the new growths which are the cause of obstruction. With the new growths radically and surely removed, the patient, if he recovers from the opera tion, will have no furiher trouble from the disease. This operation is a veryradical surgical procedure, andthe patient should be in the best possible condition to withstand shock. To keep up the strength of the patient before operation and to restore lost blood after Gude) acts with quick and certain resultoperation, Pepto-Mangan s. Its blood producing power is beyond question, as has been proven in the large hospitals after the severest surgical operations , reconstructor of known merit, and in Pepto-Mangan (Gude) is a the patient before and after opera building up the strength of tions it has no peer. Itis a scientific combination of iron and manganese, which increases the number of blood corpuscles and hemoglobin without causing gastric disturbance, which, if occur ring in cases of severe shock, must cause deleterious results. Pepto-Mangan (Gude) can be borne by the weakest stomach. 171 194 TO COME DAYS PAST Weissto fapiiodta Lo, Georgia. ; !Tic eat lawetel Savannah Mosse Norton, George Dr.«Fiano to his Clinical report appearing in the Virginia . i . o cal Semi-Monthly, July, 1902, says: 7s ot ou : o ] ec ta aud valuge ©theNee weoten acknowled ust ac ; I must report ini ‘Beforeclosing this clinical ple assistance rendered by my good friend an ie ere. gre B. Fitch, in microscopical work and Panes eonne re nee several other cases, but forclinical purposes ge : ae boraee ; serve to convince the reader that we have in Pepto-Mangan (Gt -op+ 4 qd, py le hdty Monday, June 22 June 21 “ny 7a ~4 172 DAYS PAST +> 193 TO COME 7 y ora ¥ Dr. Vehm ata eyer , Hare n, Ger many. writ ing upon the Therapeutic Value of Pepto-Mangan (Gude), says : {ts use is therefore recom mended in all those diseases in which « Inereas through an incre ase ofF blood7 and improvement of lts qualit : , y, a cure or a beneficial thrones influence uponthe organism is to be expec ted. as tor 4 , nAGIa . Instance, in : ; chloro sis, anzemia, leuke mia, in chronic idisea; sesee of the respi rator:y organ : s, in many gans, 1am diges tive gestiv dis ders, especi e disor ecial e yY after diarrhoeas, and in convalescence from various diseases. h e espec e ially in weak and anzemic women afte metanea r childbirth —_——————— i 173 DAYS PAST 192 TO COME Pepto-Mangan (Gude) therefore constitutes a valuable addition to our list of remedies. I prefer this preparation, which has never left me in the lurch, to all similar products, and am persuadedthat within its field of indications it will prove of equal service to others. As regards the dose, it is advisable in general to follow the printed directions, although in individual cases it may be exceeded without the least untoward effects; for it is one of the prominent advantages of the preparation, that while exhibiting in full its curative effect, it never satiates or becomes repugnant, but permits of administration according to requirements, for a short pericd as well as many months, and that itis equally well tolerated by children and adults of both sexes without exciting the least aversion k4 ¢ Tuesday, June 23 174 DAYS PAST 191 To COME Wednesday, June 24 AVS PAST 190 TO COME June 14. 1902, M. April 10, 1902. Capp Il. D., Phila., Pa., writes: ve used Gude’s Pepto-Mangan in anemia after a severe la grippe and am pleased with the favorable results. disturb digestion and is not objectionable to the taste.” It Oschaffenburg, Halle, a/S., Germany, writes: case in which [ tried your Pepto-Mangan (Gude) the result npletely 1d most successful. a ae palatable. When diluted with some water it Thursday, June 25 176 DAYS PAST 189 To COME Friday, June 26 177 DAYS PAST 188 ‘Tr July 10, 1902. J. W. Young, M. D., Bellefontain Ohio, says; ‘*The sample of Pepto-Mangan (Gude) was received, prescribed and taken with excellent results. Patient still using the preparation Chiorosis disappearing, strength returning, and [amhighly pleased vith its action.’ April 11 Dr. Bartsch, Alt Reichenau, writes : ‘“‘t have employed your Pepto-Mangan 1902 (Gude) in an ana mic woman during the puerperium and was extr emely satisfied with the "OC yr : r result } . Even after using one bottle a considerable improvement ensued. Iam able to recommend vi our preparation most heartily s e i =e a > Saturday, June 27 178 DAYS PAST ] Sunday, June 28 TO COME December 9%, 1901. ‘Tam very glad of the opportunity of expressing my high Be: preciation (Gude) I have the preparat ion of Pepto-Mangan : 5-Me mud ave found f he preparatio1 nstantin its action, getting results after ‘t 5 failure with UT other I chal a LY; beates. Ishall continue c its use in my practice. 186 To COME April 30, John W. Winley, M. D., Benton, Pa., writes: consté 79 DAYS PAST = 1902. Dr. Volibrecht, Darmstadt , Germany, writes: ‘“In mypractice Pepto-Mangan (Gude) ha:S given good servic e in anemic conditions8, acute and ‘chr onic, and in dysmenorrhea, patients take the remedy con The tinuously without aversion, advantage: of the| an >prepar ation overMany otheTS? / f f } Tuesday, June 30 Monday, June 29 185 L. TO COME Woodruff, Woodruff, Pa., says: ‘*T desire to express my esteem and admiration of that wonderful ; 2 ‘ } t= hae preparation, Pepto-Mangan (Gude), which is one of the » be st, ifif not the best of medicines, and will reach and relieve more suffering humanity than any other preparation now kn@wn Z Ls _ eee a a l ‘ = Se 181 DAYS PAST 184 To CoME Dr. E. Zbinden, Orbe, writes: “[ have lately had occasion to try your blood-buil Mangan (Gude) in th case of a young anzmic perso der Pepton, in which other treatment had proved unsuccessful. The result s have been rapid and excellent.” Wednesday, July 1 SVS PAST 183 TO COME ae July 2 183 DAYS PAST January 20, 1902 June3, 1902. W.E. Walter A. M., M. D., Lone Elm, Cooper Co., Mo LB] be nusing Gude's Pepto-Mangan for four years in my 0 anaeshave found it to be a most welcome helper in malaria, ‘ia, chlorosis. reverindicated etc., and am now prescribing it in my practice 182 TO COME Dr, Forschelen, Grossenbaum, Germany, writes ; ‘‘My daughser suffered greatiy trom malaria, her strength be ing Your Pepto- Mangan (Gude) gave excellent results, much reduced. Micreasing the appetite and promoting a gainin strength, In my practice 1 have frequently prescribed your preparation and am disideas satisfied witk the eSUA tS é , Saturday, July 4 Friday, July 3 184 DAYS Past 180 TO COME 131 TO COME June 17, 1902, Dr. J. Flagg, Worcester, Mass.. writes : ‘“Thave used Gude’s Pepto-Mangan eight years, and find that this preparation in my practice for over is the best among the different iron preparations that I have used”, “In anemic and chlorotic Conditions, it has proved especially valuable to me, and I shall continue the use of Gude’s Pex to-Mangan in all cases where an iron of this character is indicated.” Dr. P. Plattner, Estavayer, writes : “I have employed your blood-bu ilder Pepto-Mangan (Gude) in several cases of severe anzemia and during convalescenee from severe infectious diseases. The result was good and satisfactory , The remedy was gladly taken and well borne. The appetite and strength increased rapidly and the hem obin percentage of the blood was augmented proportionately, ogl Unpleasant by-effects have never been observed by me. 1 will cont inue to use your bloodbuilder, although it is my custom to employ as little as possible these so-calle d special preparations.” Sunday, July 5 186 Days PAST ~July26, 1902. Dr. J. B. Williams, Washington, D, C., writes: **Sometime ago yousent me a bottle of Pepto-Mangan (Gude), for trial. Ehada patient 5 years old, who, when a few months old, developed asevere case of rickets. Thoughproperly dieted she made slow recovery, marked neurasthenia, etc. Iput heron half teaspoonful doses t.i.d. and on the 25th day her nervous condition and blood had so improved, I called in one of the most successful pediadrists of the city, who was surprised to see the great change. I ordered a second bottle and to-day thelittle erstwhile sufferer is as gay and looks as healthy as any of her playma tes. I have used it in Other cases with equal success,’ Monday, July 6 87 DAYS PAST 178 TO COME January, 1902. Dr. De Raedt, Ledezheme, Belgium, writes: ‘“‘T have tried your Pepto-Mangan (Gude) and amable to speak in termsof praise of the results obtained. May1 avail myself of your kindness by asking you to send me an additional supply of two or three bottles, I have under treatment a poor patient who is getting well under the use of your preparation and who is extremely anxious to obtain it. I desire to continue its employment until she is fully restored to health. I have not failed to recommend particularly your admirable remedy.” Tuesday, July 7 188 DAYS PAST Wednesday, July 8 177 TO COME October 25, 1901. Dr. Ff. V. Thompson, Phila., Pa., writes: I gave the bottle of Gude's Pepto-Mangan which you sent me © a chlorotic patient and it did her a great deal of good. I found such a decided improvement that I have prescribed this medicine in similar and anzemic eases with benefit.” 189 DAYS PAST 176 TO COME April 21, 1902. Dr. Jorend Jozef, Erdo-Szt, Gyorgy, Hungary, writes: ‘I have tried your Pepto-Mangan (Gude) in anzemia, especially in children, with the best results, and have the experience that patients showa preference for this preparation.” Thursday, July 9 175 TO COME 190 DAYS PAST THE POWER OF THE BLOOD is lost if the quality of the blood is poor. Build up the quality of the blood by increasing the amount of Hemoglobin and the number of red corpuscles, and like the force of Niagara, the power of the blood to build newtissue and repair waste will be tremendous. Pepto-Mangan (Gude) improves the quality of the blood rapidly and surely. Results are positive and can be proven by scientific tests. / Fo 4) f Fees = Ay ; . J be Friday, July 10 191 DAYS PAST 174 TO COME The following cases are taken from the published Clinical Report of Dr. Juan Pablo Garcia, after an investigation with Gude’s Pepto-Mangan at the San Francisco de Paula Hospital, Havana, Cuba. CASE 1.—J. D. G., 10 years of age, weighing 52 pounds, was seized with malarial infection two years previously, but since then there has been no recurrence of the disease. The red corpuscles numbered 2,875,000. Pepto-Mangan (Gude) was administered in doses of two teaspoonfuls daily, one in the morning and onein the afternoon. Fifteen days later the dose was increased to atable- spoonful twice daily, morning and afternoon. Two months later the examination of the blood showed 3,942,326 red cells. The patient had also increased in weight to the extent of 13 pounds, and had greatly improved in general health and appearance. 5 A Saturday, July 11 192 DAYS PAST 173 TO COME Dr, Juan Pablo Garcia,—Continued. CASE 2.—R. G., colored woman, age 27 years, single. Her icous membranes were very pale, she waseasily tired, complainea of lassitude and had a weak pulse. She weighed 96 nd gave a history of painful and irregular menses, anda leuc discharge. On examination her red corpuscles were Lol > nun iber 2,385,714. Three months and a half after the be— ginningof the Pepto-Mangan (Gude) treatment all the above mentioned symptoms disappeared, her weight increased to 124 pounds, i her menses were regular and painless. The red corpuscles at 1at time numbered 4,532,000 per cubic millimetre. -—-- CASE 3.—P. C., nine years of age, weighing 37 pounds, a daughter of tuberculous parents, with a tendency to catarrh, expectoration did not contain any tubercle bacilli. She was suffering from constipation and had a pronounced anemic look. The blood count revealed 2,150,000 red corpuscles. She was put under the Pepto Mangan (Gude) treatment in the manner described in case 1, and began to improve rapidly. Sixty-one days later her weight had increased to 58 pounds, and the number of red corpuscles to 4,550,000. i ——KKKKe———ce— SS J 5 ’ Jf f Tuesday, July 14 Monday, July 13 eT 171 TO COME t from Dr. E. C. Girls to Hill’s article ‘*‘Howto Assist Womanhood.’’ to Emmet. more than half of all women who have uberty frommenstrual derangements are sterile and f after ; life. Skenee has stated that his observations the vast majority ol incurable diseases peculiar to 1 TY raortarct atTA ry t > n a nat rx ae rfect development and consequent derangehis devel me | ither pri yr j his development is either primary, during the of function. ynen O01 nt oy et r ondary, at puberty. Defects in the former bryonic stage, or =secondary, is ae eee A I mediable, Ww 1ereas secondary deviations from the normal y ) 7 ore e both preventable and curable in most instances.” ; = 170 TO COME 195 DAYS PAST Medical Century, August, 902, 5 luding to Gude’s Pepto Mangan: worn-out system ‘Tt seems in a marked mannerto restore the It does normal processes. andto enable nature to again take on her every preparation of iron for it, does not seem to be the iron that us, ever. quite frequently: but that we have used has at times failed ut doubt owing to the witho is n ratio prepa the success of this We can Manganese the with judicious combinationof the iron Century as worthy the of rs reade the to n ratio prepa commend this a thorough investigation.’ of ny eacme we ei Dee ae ET 7 9 y i _ESUROROAY aay oe a ——s a or blood : : tainted . ee HEREDITARY ; with Saas syphilitic : BLOOD ? virus, ; tubercular blood to become poor in ppear. blood, healthy blood attacked by will keep the body the insidious foes which pu re and New blood, rich Jess liable to be PAST Sere dition of the blood. The patient gains in weight and strength and the body is better able to ward off the impendingdisease = A mae » 28. pune Dr. J. hes = Wee ‘““T used suffering a : 1902. Ee Cararach, Barcelona, San Andres, Spain, says: fay Se rs (a ; ada » ttre ent of a young g lad} lady Pepto-Mangan (Gud pheee type i After the from ae h rt completely of which I all fe sientee (Bi administration of three bottles sne recovere sh: > Vy yout yur preparat reparation in & employ and shall am pleased to notify you, eases in which itis indicated. Ss Se devastate entire families. Pepto-Mangan (Gude), if given in incipient tuberculosis and all wasting diseases, will build up the system by building up the con- J Thursday, July 16 ; 168 TO COME ’ familiar quality and immediately — J 44 € ; ‘ . Cane a and degereracy of disease characteristics sh DAYS diathese ees en blood, preter sition to carcinomatous ylood,; scrofulous diatheses are all cases continually If : ; 2met with. : the blood can be maintained at the proper standard, the predispo sition to the so-called hereditary conditions will disappear. Allow the - 197 f ———— Saturday, July 18 Friday, July 17 198 DAYS PAST 167 TO COME Extract from clinical report by Dr. J. W. Frieser, Vienna, Austria. .Therapeutische Monatshefte, April, 1902 ) ‘An especially advantageous influence is exhibited vy PeptoMangan (Gude) in the case of weakly, anzemic, and ill-nourished chilGren, as wellasin anemic women. In these cases its use often proves most serviceable, so that I have learned to awardit the preference and prescribeit usually with excellent results. ‘Particularly striking was the success of treatment with PeptoMangan (Gude) in three cases of very severe chlorosis and in two cases of marked acute anzemia following considerable losses of blood. Ina comparatively short period of adm/‘nistration (five weeks) a most remarkable improvement, both of tho general state and the appearance of the patient, as well as of the condition of the blood frapid increase of the number of red blood cells and percentageof Cc? A x ; 166 TO COME 199 DAYS PAST Dr. J. W. Frieser.—Continued. hemoglobin), took place. I cannot refrain from mentioning that in everal cases in which the administration of iron appeared contrain- a dicated owing to marked digestive disturbances or to an a febrile state, Pepto-Mangan(( rude) was prescribed by me W ithout s. uny drawbacks, but rather with eminently sat isfactory result “ According to all these observations In my pletely confirmed by manyfa vorable reports [ practice, wich ars from othe! a ent on os ee would regard Pepto-Mangan (ude) as an € the Ire among place nt promine a emedy, which is entitled to parations at present at our disposal, Sunday, July 19 20@ DAYS PAST 165 TO COME March27, 1902. Dr. Geo. S. von Wedelstaedt. Chicago, Ill, says: ‘‘In the past five years your preparation Gude’s Pepto-Mangan has been the only tonic prescribed by me in anzemic conditions. Have prescribed hundreds ofbottles of it, and shall continue to doso, always being assured that the patients procurethe original. Have been rather run down of late, and in this case ‘‘willtake my own medicine”. My results in using Pepto-Mangan (Gude) have been truly remarkable. Have about ceased reading the reports sent out by you narrating its wondrous effects, as I believe not a one can surpass those procured by me. You are trulyto be congratulated in aving so excellent and unexcelled a therapeutic agent.” Monday, July 20 201 DAYS PAST 164 TO COME AbstractfromArticle by Dr William. RedinKirk, Ph. G., M, D., Hendersonville. N. C., entitled ““Some remarks on the Use and Abuse of Drugs in the Treatment of Tuberculosis.”’ ‘When, however, a blood examination shows the hemoglobin to be below par and the redblood cells deficient, I amin the habit of giving some preparation of iron, alone or in combination with iodine or arsenic. Pepto-Mangan (Gude) I have found to be the most easily borne. Under its administration the hemoglobin and the red cells both increase. It is palatable and easily assimilated and has the advantage of notaffecting the teeth.” Tuesday, July 21 202 DAYS PAST 163 TO COME February18, 1902, Dr. 0. F. Fleener, Knightstown, Ind., says: take much pleasure in saying that I have been using PeptoMangan (Gude) in mypractice for three years and it has always proven to be the best preparation on the market, of any iron Wednesday, July 2% 203 DAYS PAST 162 TO COME November 1, 1901. J. F. Dustin, M. D., Alexandria, South Dakota, says; “I have been giving Gude’s Pepto-Mangan to a patient suffering from pulmonary phthisis, and am—more than pleased with the Thursday, July 23 204 DAYS PAST 161 TO COME Dr. Ramon M. Alfonso, Havana, Cuba, says: vould testify that I have used with satisfactoryresults, in those ons of more or less advanced malnutrition, such as convelescachexy and tuberculosis, the excellent preparation known yto-Mangan (Gude).” Friday, July 24 205 DAYS PAST 160 TO COME June, 11, 1902, Meigs Denis, M. D., Hardaway, Ala., says “T am entirely satisfied with results obtained in cases where ] have used Pepto-Mangan (Gude.) I have used it chietly in anzemiec cases requiring tonics where digestion was impaired, in every ease being perfectly satisfied with its action. Perhaps the most con vincing proof I can give you of my appreciation is to state that since receipt of sample I have ordered nine bottles of my druggist. Saturday, July 25 159 TO COME vO +h I take a great deal of pride. n under treatment for several years by various covery to your excellent preparation Pepto‘right hand in all cases of malnutrition, sconstructive. ry anemic. I find it especi- Could not retain the So weak could not walk from rregular menstruation. Upon erosion and laceration of cervix. When Ifirst wa Was in such a weak condition that I could not on cervix as indicated. Put her on strychnia, iron and and other drugs as indicated which wereof no avail. Then our Pepto-Mangan (Gude) as a last resort, teaspoonful four with sherry e. Result, was able to operate on herin n vas continuous until her health was en- Sunday, July 26_ 207 DAYS PAST Case 1I.—H. B., chronic gastritis, chial cough, cular and ad no lung ’ a 158 -Continued. sevel suffered Had age 41. weak and very n¢ ous Hada bad . bron His condit ion wasdiagnosed as tuber m could find I pon e3 qa ninat » Colorado. rhatsoever, Restricted bowels kept open py salts in hot water before on teaspoonful doses Of Pepto-Mangan (Gude which he dropped one drop of Creosote two weeks he had gained 14 pounds patients diet, ordered breakfast. y thi Put him hours in At the end ol Beechwood). Slept bette r and was getting - sieht weeks I discharged good eoior in his face, and at the end ef eigh . Mangan PeptoGude’s to thanks cured, him ——————_— Monday, July 27 208 DAYS PAST 157 TO COME Tuesday, July 28 209 DAYS PAST 156 TO COME May 30, 1902. Dr. Rich. Wernecke, Berlin, Germany, writes: “| bave tried your Pepto-Mangan (Gude) in a ease which terminated se favorably that I shall always prescribe it in apprepriate eases.” 7 April 27, 1902. Dr. Jerome Gleason, Swains, N. Y.. says; “In regard to Gude’s Pepto-Manganwill say that it has no equal for those who are run down, and in the case in which I used the bottle you sent me, the patient grewstrong and gained in flesh every day, so I cannot speak too highly of it.” / cate tes? Bihen ‘yh } / ALLn ( Bs = 210 DAYS PAST hurs 155 To COME eee ee ee September13, 1901. Wm. N. Beggs, A. B. M. D., Editor Colorado Medical Jour- nal, Denver, Colo., says: 30 Anko “Tee T Wednesday, July 29 211 DAYS PAST —_— ay 5 y U 154 To comME ~ - November 1, 1901. Dr. E: W. Murray, Chillicothe Sanitarium, Chillicothe, “In my extensive practice, say 90% among pulmonaryinvalids. | have had freauent occasion to use Gude’s Pepto-Mangan. Clinicly, I find it of very great value in the aneemia of tuberculosis. Of Mo., Says; “J prescribed the sample of Pepto-Mangan (Gude) in a case of anzemin and am pleased to report a gain of 4 pounds in the patient’s improvement has been noted and I have at times been really sur- prescribe it with confidence.” eourse, in manycases little is to be hoped for, but in others marked prised at the results obtained,” weight after taking the preparation ten days. eee Weiol a7 Ce 20 L shalt continue to : saturday, August 1 Friday, July 31 212 DAYS PAST Dr, J. S. Chagnon, W 213 DAYS PAST 153 TO COME be giveh without upsetting the most delicate stomac h, ‘stores the blood to its normal condition.” February 5, 1902. Conn., says: ‘I have used Gude’s Pepto-Mangan extensively in my practice for some time nowand noform ofiron [ have heretofore used has given me such unifor-nly satisfactory results. In the various anzemias it can and rapidly 152 To COME Dr. F. D, Clum, Cheviot, N. Y., says: “I prescribed Gude’s Pepto-Mangan in a case of a scrofulous patient who was weak and anemic, and judging from the improved condition of the patient while taking it, | am satisfied that it is an ideal preparation, and I shall take pleasure in prescribing it when everindicated.” Sunday, August 2 PAST 151 TO COME Monday, August 3 215 DAYS PAST 150 TO @OME March 12, 1902. November9, 1901. Bradiey, Whitehouse, Ohio, says: cross a preparation more meritorious than it will take the lead wherever tried, Peptoused in all cases and cannot be used amiss, h said in favor of Pepto-Mangan (Gude.) itor and vitalizer. . I shall continue to pre- Besides what it is generally used for ] iin kidney troubles, where the cause is due to uric well as in general debility and rheumatism.” Dr. W. T. Bond, Philadelphia, Pa., says : “I have prescribed your Gude’s Pepto-Mangan and rely on it for rapid and lasting results, Ihave prescribed it no less than 50 times in the last 10 months. The first case in which I used it was a patient suffering from anzmia and chronic inflamation of mucus lining of duodenumand bile ducts. He had suffered for years, His weight on commencing treatment was 113 pounds. I prescribed Pepto-Man gan (Gude) and in 17 days he had gained 9 pounds, and averaged about 14 pounds weekly. When we find a preparation whose merits speak as loud as Gude’s Pepto-Mangan it is truly miraculous.” / DY, OT, rh by. y f ) Tuesday, August 4 Wednesday, August 217 DAYS PAST 149 tO COME me es 5 148 aOEEESR= DT 3 : TO COME May1, 1902. Dr. W. H, Besrman, San Fransisco, Cal,, says: December 6, 1901. Martinez Avalos, Havana, Cuba, says: “J have sure in informing you that I have used with very Pepto-Mangan (Gude) in rachitis and rebelious found that your Gude’s Pepto-Mangan is all that is claimedforit, and I shall certainly recommend it in my practice. I find that special beneficial results can be obtained in casesof severe nervous troubles, remarkable.” of, \/ and in such short duration that it is simply Thursday, August 6 vs $1 147 TO COME Friday, August 7 146 TO COME 219 DAYS PAST March 8, 1902) October 30, 1901. Brown, D. D. S., Philadelphia, Pa., says: gratifying results from the use of Gude’s Peptocases where I have prescribed it. The fact thatit ny deleterious effect upon the teeth recommends it in r good qualities pre] sessed. I shall continue to pre ron is indicated.” Dr. J. FE. Benitez, Chief of the Laboratory of Hospital No. 1, Havana, Cuba, says: “T have the pleasure to inform you that the use of your Gude’s Pepto-Mangan has given the most satisfactory results, as it has been proven by ourobservations in above hospital.” q a aa jj _ Saturday, August 8 290 «~2<0 DAYS PAST 145 To ‘COME is &@ much easier proposition to clai ’, etc., than to producea scientific m “Just as§good”, “Just the combination and. then subto the Medical Profession after being put to the severest Gude’s Pepto-Mangan has unde rgon e the scrutiny of the 1ysician and has proven its wort h. There has never been a stat emen Gude’s Pepto-Mangan but which t made regardingthe efficacty of can be substantiated byscientific nvestigation. Combinations claiming to be the same are simply nten ded Me dical for substitution and Profession. Ee a have never been endorsed by the Sunday, August 9 221 DAYS PAST 144 Yo COME April 19, 1908, Dr. Chas. W, Gibson, SecretaryBoard of Health, Batesville, Ind,, says: ‘About four weeks ago 1 began using your Pepto Mangan (Gude), and have been wateching two cases of anemia on ee hei treatingfor the past year. Both cases have improved « ecidedly, gained in weight and general appearance. I am we ll pleaserd with your preparation so far and shall continue to use it in the cases above mentioned until I get its full benefit. Tuesday, August il AYS PAST 142 To COME Dr. I. R. Goodspeed—Continued. Dr. I. R. Goodspeed, San Mateo, Cal., says : ‘Tamnot in the habit of writing up cases, but I feel it is my duty to give my experience with your Pepto-Mangan (Gude). Case I, Mr. R., age 40. Until about one year ago enjoyed the best of health. At +t this time he had serious sickness in his family which interrupted d his digestion and he became anemic. He wastreated homeopathically with red bone marrow and other remedies until about one month ago. At this time I was called to take the case. He was so low he could not raise up in bed without fainting. Could not eat anything. In fact I was advised not to take the case, as it was thought he could not live but a few days. Iat once put him on Fowler’s solution and Nux Vom., also Tinct. Gentian with Chl. Iron, Ps — - - = Followed this treatment about ten days. iatinivaltendiwas daa ory bad very much hope > P OF is r ry war 2 Ca as Wednesday, August 12 oe% DAYS PAST 141 TO COME Dr. C. A. Burdsal, Hanover, ind., says: £ GiWwW le’s Pepto-Mangan sent me in a case of h tional disease of the heart. The results e pe it is now quite well. I think I 1ufactured for medicinal purposes, results as obtained from Gude’s Thursday}; ursday,9 925 DAYS PAST Dr. P. A. Brown, Beeva, W. Va., ‘IT am continually encounteringcases of painful 1as continually prescribing Pepto-Mangan (Gude) .cedented success with this preparation in such » Pepto-Mangan (Gude) for all menstrual tation, as I am alwayssure ofa speedy Saturday, August 15 DAVS PAST 138 TO COME February 8, 1902. Dr. J. H. Hagy, Mendota, Va., says: ‘T had a marked annoy has re Ly increased bne use oj i 4 ; ease of chlorosis which had the ordinary tonics without any material : young lady, who looked very anemic, f try o t d le ete. *, irres and scanty ion ritable, menstruat and ”s Pepto-Mangan, so I sent for a sample bottle from you almost taken has ‘She daily. times three l teaspoonfu a her ‘ttle. One could hardly believe that such a change could be She looks a great deal bet 1t about in such a short time. } . nas : ; eA gooa ay a 1I »petite, e’s menstruation much more regular and I certainly am well pleased so far with am confident another bottle wil eom and Pepto-Ma1 igan, Q 2 uantity almost1 1ormal. pletely cure her.” Monday, August’ 17 A9NQ Sunday, August 16 Ss 15/ November 28 oo, “*fO COME T used in my own family Ll have since bought more at the drug store, which is pretty good evidence I think well of it [t has agreed with the patient splendidly, and has done her so much good, It goes TLE (Gud Pepto-Mangan nd inanition, folowing a months ago. The LVUL. Dr. B. Roscoe Gary, Newport News, Va., says: ‘The two bottles of Pepto-Mangan (Gude) you kindly sent me Dr. J. Harry Hendren, Louisville, Ky., s of 136 TO COME y case indicati f without saving, lam using it very often in my practice.” — esac = Tuesday, August 18 Wednesday, August 19 135 TO COME PAST 134 To COMI December 20, 1901 & Ray Beardsley, Binghamton, N. Y., says: Gude’s ’s Pepto-Mangan P ler our health an imp care by extensively. during this rished the Hjundreds — past remedy... ndition in of few . May10 1902. Dr, Muller-Herrings, Imperial District.Physician, Saarge, c of mund, Germany, writes: years chlorosis the blood as with your Pept Ma “T am much pleased i well as in anemi:a after loss of bl ‘ ice. and prescribe it. Scar ely a day passes in my It does not cause castric dis trary, stimulates the appetite to a marked ¢ in (Gu 233 .DAYS Thursday, August 20 DAYS PAST Pepto-Mangan 2 ee January re 2, h1902. : continues to be the only reliable reparatéon on the market, notwithstanding theefforts on the part ous manufacturers who claim for their products that they are ; as good COME November 24, 1901. Dr. E. J. Miller, Everett, Pa., says: ‘“Gude's Friday, Aug ust oe TO PAST an fa a, S,, Saukville, Wis., says: Dr. T, A. Birwick , B. S Pepto- “The> high standard of efficiency maintained in ON eer pee ig svadllac = : urhiel very yn Vsicie c Manean makes it a preparation upon which every ] ee | depend. ee August 23 Saturday, August 22 AYS oO PAS PAST 131 3 TO COME ai april 29, 1902. January 30, 1902. r, Jose aeee N, [lace ceo, Direc tor Franc i isco V. Aguil ALCISC era Hospital, ilere i uerto Padre, says: : sige using with several p: oS‘ie in this Hospital and in practice Gude’s Pepto-Mangan with good results, mainly s at the sam NAA ¢ rule cine 4 ee poe time a ; aeAl auxihary in the treat hema and malarial ecachexy Ld ot hesitate ommend it as a compound which mi oecupy a ae Materia Medica.” Ay. 4 J 1Csiba 130 TO COME 235 DAYS PAST ~§ Dr. L. TicGee, Zona, La., says of Pepto ‘In regard to my experience with the sampie bottle very were results the say will sent, you which (Gude) n Manga ing follow a, anzemi of case special 2 for d sat isfactory. it was ordere ed all an attack of malaria some months ago. The case had resist bottle of forms of iron, arsenic, etc., but after taking the sample ement. Appetite Pepae un (Gude), I can see adecided improv J have no meansot making as increased, menses fairly abundant. without.” abloodcount, but the improveinent is sualcion! to note % / j onday, August 24 LYS a si Z 129 TO COME PASI —— December 2, 1902. { ’r. Ulpiano Hierro, Physician and Surgeon of the Hospital Tuesday, August 25 of St. Mercides, Havana, Cuba, says: L have for some time been prescribing Gude’s Pepto-—Mangan pa tients, and have observed satisfactory results where it rdered mw all persons suffering from anemia, scrofula, hitis, and during he various stages of convalescence. I will een mtinue to prescribe t end it.” A+ 1e preparation and do not hesitate to recom- 128 TO COME DAYS PAST January11, 1902. M.O. A. Hunt, M. D., Manchester, N. H., says: “JT am a friend of Pepto-Mangan (Gude) . appointed me. It has neverdisIt has brought the roses ot health back to faded cheeks, brightness to the eye and tone to the weary muscles after the fight with disease, and in all cases in which I have tried it J nave been satisfied with the results. never hear any objections.” It is so pleasant to take I Thursday, August 27 We dnesday, August 26 12. 27 TO COME November 30, 1901. Tlass., says . G. Tioore, Ro e of Mr 3..——, who has been lmcnary consumption. She metime, andshe told had diagnosec 1 her CE ner ] family. earance heT° aj pe xe neral heaith October 23. ri it over improve under 9 nA ‘fy ~ 126 TO COME 239 DAYS PAST November 20, 1901 Dr. A. J. Lieber, Henderson, Ky., says: -Mangan ((Gude) received threugh your “The bottle of Pe»pto-] courtesy has been taken byone «of mypatients, w ho is fourteen years old and very anemic. I was so w ell pleased with the results from the first bottle thatIi had her continue the use ofit. i Sheiis now on eebottle. Her appetite has improved wonderfully and her veneral appearance so muc h as to be noticeable and commented upon by ics acquaintances, Most chee rfully do I recommend and fo anemia, pre ser ibe Gude’ Ss Pepto-]Me angan for Saturday, August 29 Friday, ¥D Au st October El. 1901. Lae * 4“ 125 TO COME AS] December 17, 1901. any, says: Dr, Otto Lauenstein, Hamburg, Germ | have used your Pepto-Mangan (Gude) with the best results. I n facet, a great friend of your preparation and prescribe it tremely often | must confess that every new experience with it 4 me more satisfied, and when | am compelled to resort to ‘iousness of the patient, 1 reparations because of the cap do so with compunction, and | am 124 TO COME ee bow 28 glad to return to 1b) l, Des Moines, Dr. E. E. Dorr, Editor lowa Medical Journa la., Says: ‘J have not ietary been in the habit of endorsing any propr write what I am go medicines, and presume I ought not personally came under m) lady young a ago ing to say, but about two years I placed het weak. mely care whose physicial condition was extre ol instructions to drink a glass upon Gude’s Pepto-Mangan with times daily. In four weeks she milk at each time of taking _four had gained twenty pounds.” = aes Nace ee Monday, August 31 sunday, August 30 DAYS PAST 243 DAYS PAST 123 TO COME : - Leo, December11, 1901. Surgeon-General (Retired), Plauen, Saxony, writes : ‘Inall appropriate cases in which I regard the use of your PeptoMangan (Gude) indicated I have witnessed such brilliant and avorable results as to afford me complete satisfaction as well as to gain patients. Its [general effect manifests { veral weeks, the improved gastric and followed by a better and more complete ia ovement in the condition of the ‘ation, which is well tolerated, is ‘onstitutional diseases dependent upon of the blood and insufficient nutrition espnec }pecially the nervous system, as well truation and in diseases of children, in sspondingly diminished. As in the case of us the cause of the favorable effect is not ttue dose, whic may be very small, but lilation in the blood and the tissue 122 TO COME August 14, 1901, W.E. Fitch, M. D., editor Georgia Journal of Medicine and Surgery, Savannah, Ga., writes: ‘Since becoming acquainted with your excellent prepara tion, Gude’s Pepto-Mangan, with which I have had the most pleasing re sults in the treatment of anzemia, chlorosis and other debilit ated conditions, I prescribe it in all cases of debility or malnutrition, or where there is need to improvethe appetite or stimulate the blood. This pleasant tasting compound of organic iron and mangan ese causes a rapid and progressive increase in the number of red cor puscles, and in the percent age of hemoglobin in all cases of ana mia, chloro sis, etc., whether due to organic disease or functional dis rder. Tuesday, September 1 yy rh ‘ A 121 TOICOME vS PAST August 8, 1901. Professor W. F. Loebing, Innsbruck, says: ressed mysell in my former communication as completely with Pepto-Mangan (Gude), and emphasized that it had ry serviceable in anzmic children asa means of improving te, and thereby the general nutrition and condition of the a matter of fact, the results obtained by me have ny colleagues in several places in the Tyrol and Vorarlberg the preparation. It has also proved very useful in my chlorosis in girls at the time of pubertyas well anemia. wn isfied v if Wednesday, September 2 245 DAYS PAST 120 70 JUDE’S PEPTO-=-MANGAN. Produces good healthy blood quicker and with greater increase of red corpuscles and hemoglobin than any known remedy, as demon strated by actual scientific investigations in the largest 1Ospltals OF Clinical reports, essays and samples sent Europe and America. gratis on application. xi. Specify Gude’s and CauTIoNn.—Prescribe an original bottle on bt eae Thursday,a Sept embe r;cy F a 246 DAYS PAST 119 To ComE "August 22, 1901. (Geo. Thos. Paimer, M. D., Medical Director of Diet Kitchen for Infants, Instructor is **Tn thosecases of « Tound1 tou the ths that he those t * organo-meteé iron. the The admin chloric ich iron 7} indi ; which iron is indicate2d, it has ]been is coming under the g tly superior to the ord -h @ preparation astl y gastric irritation and . 1 Gude’s Pepto-Mangai listurbanc rj given 1 WW is } 1+ + withoutthe s . f rot 4 *ha + } , Ia Listurbance to the most: delice tion nilation head 1]< of { Po i t > stomach > ft _ Pepto-Mangan des Friday, September 4 118 TO COME 247 DAYS PAST en 20, 1901. Dr. H. Edwin Lewis, Ed. Vermont Medical Monthly, Burlington, Vt., sa ‘Tn regard to my opinion concerning Pepto-Mangan(Gude), { consider it the best and surest iren preparapermit me the medical profession. There is no other tion at the halybeate tonic » and feel of imitations so confident of satisfactory ; to me with (Gude) Pepto-Mangan’ “just as good that the claim D Mat ee : he standar pe Staneae™ that Pepto-Mangan (( di confirms my op I shail use i bette r than the standard, "( nothing s Therefore, as the ; it fulfills | ev ery requirement and has nothing else, particulils never disap} Saturday, September5 248 DAYS PAST 117 TO COME Abstract from Medicinisch-Chirurgisches Central-Blatt, Vienna, Austria, January, 1902, ‘A Contribution to the Therapeutics of Anzemic Conditions,’’ by Dr. Hermann Metall, Assistant Physician to the General Polyclinic, Vienna, Austria, ‘The advantage of Gude’s Pepto-Mangan is that it exerts a stimulating effect upon the blood-forming organs, these beingexcited to greater functional activity, and that the favorable effect manifests itself even within a short time by an increased oxygena- tion of the blood. At the same time, this chalybeate, as already mentioned, causes no digestive oisturbances and does not injure the teeth, Sunday, September 6 249 DAYS PAST 116 IN NEURALGIC DYSMENORRHOEA 5 we find those cases which suffer from Rheumatism, G temperament, ria, usually anemic, of a highly susceptible nervous condition nas an and often hysterical. The woman’s general should intimate relation with her suffering, and receive its full share of attention. in treatment Many women frequent!) state or nervous and that they suffer only when run down, overworked, this condition: t regard in states an worried. A leading physici av ieast “J have seen menstrual suffering, if not entirely cured, system.” n dow run ly general a of up g buildin the by much lessened merit, hase Pepto-Mangan (Gude), a chalybeate tonic of tested conditions oI proven of inestimable value in rebuilding run down. Dee the general system. In Anemia, Amenorrhea anc promp en hasbe actlon its rhea, Menorrhagia, Metrorragia, and efficacious to a marked degree. ach or produce nervous sequel. f It does not disvres the stom- er rails. Slept? onday, September 7. BY, port of vith Gude’s Wiad novel Gee tration 30 mitimeti olohin— Tale | ap | 8 L1L+ 115 To COME Montreal, | TO Thursday, September 10 253 DAYS PAST dnesday, September PAST 113 , ‘OME 112 TO COME Dr. Louis CASE 4.—A woman, tion, 30 days. age First count, millimetre; second count, 3,50! 9, Ansemia. red Time of administra— corpuscles to the 0 to the cubie millimetre. olobin—first examination, 50%; second examination, 60%. cubic Haemo- Saturday, September 12 110 TO com:E DAYS PAST reneged Dr. Louis Jos, Gravel.—Continued. ni ae So ae count, 3 bo 006 to the second mination. 33%: wT ss : i _ CASE erm, girl, aged 16 yea fever. ReneA following typhoid Timeof administration, 30 days. First count, 2,900,800 red corpuscles to Ke cubic millimetre; second count, 3, 860, 000 to the cubic millimetre. examination, 607 Hzemoglobin—first examination, 38%; second Monday, September 14 Sunday, September 13 256 DAY PAST 109 TO COME Dr. Louis Jos. Gravel.—Continued. SE 7.—Agirl, aged 22 years. Anemia. Time of administra7 First count, 2,246,000 red corpuscles to the cubic 2; second count, 3,400,000 tothe cubic millimetre. xamination, 40%: second examination, 60%. Heme- 108 TO COME 257 DAYS PAST Dr. Louis Jos, Gravel.—Continued. CASE 8.—Agirl, aged 20 years. Anemia. Time of administra- tion, 30 days. First count, 2,460,300 red corpuscles to the_cubic millimetre; second count, 3,800,000 to the cubic millimetre. Heemoglobin—first examination, 86%; second examination, 602. j a (ff nie Wednesday, September 16 Tuesday, September 15 107 TO COME 258 DAYS PAST ; Dr. Louis Jos, Gravel.—Continued. CASE 9.—A girl, aged 24 years. Anemia. Time of administra~ ion, 30 days. First count, 2,709,300 red corpuscles to the cubic millimetre: second count, 4,125,300 to the cubic millimetre. Heemo~ slobin—first examination, 40%; second examination, 64%. : re fee ee 106 TO COME 259 DAYS PAST — = s, Gravel.—Continued. CASE10.—A man, aged 40 years. Anzemia following Dysentery. Time of administration, 20 days. First count, 2,246,800 red corpuscles to the cubic millimetre; second count, 3,936,560 to the cubic millimetre. Heemoglobin—first examination, 32%; second examination, 68%. Thursday, September 17 105 TO COME 260 DAYS PAST 4 / Friday, September 18 261 DAYS PAST 104 TO COME Dr, Louis Jos, Gravel.—Continued. Dr. Louis Jos, Gravel,—Continued. CASE 11.—A woman, aged 32 years. Anemia following laparotomy for pyosalpinx. Time of administration, 30 days. First count, 2,173,400 red corpuscles to the cubic millimetre; second count, 2,850,000 to the cubic millimetre. Heemoglobin—first examination, 30%; second examination, 43%. CASE12.—A girl, aged 25 years. Anemia. Time of administration, 30 days. First count, 2,543.750 red corpuscles to the cubic millimetre: second count, 4,170,290 to the cubic millimetre. Hzaemoglobin—first examination, 43%; second examination, 704. —— pee re y a _saturday, September 19 3 TO COME “COLORLESS |EARS tell the story. There isno need of a microscopical examination to learn that the blood is poor in quality, thin and weak in its ingredients. The waxy pallor reveals to us only too plainly the lack in numberof red corpuscles, the presence of Anzemia and its sequelee. The shell-like pink of health is replaced by the ae y appearance of ill health and wasting disease. What can be done to stop the inroad of disease ? Pepto-Maz gan (Gude), by, building up the blood, acts as a general tonic <and reconstructor, repairs waste of cellular tissue, stre ngthens and improves the general condition of the patignt. peeeee ae Seer ores eRe SSS SRLSfae wen rf it searhai September 20 263 DAYS PAST 102 TO COME Extract from Clinical Report.byEE -C. Hill, M. D., Reaver. ol., entitled ‘*‘ How to eee Young Girls to Ww oman= hood,’’ from Brooklyn Medical Journal, July, 1902. ‘‘Most authorities conclude that inorganic compoundsof iron in order to be absorbed must first be changed to albuminates by comining with food matters. All albuminous substances are hydro- lyzed to peptones before they are capable of absorption. Hence it follows that a peptonateof iron is the preparation most li kely to be readily and completely absorbed and assimilated. The best resea : this composition, I think, is Gude’s Pepto-Mangan, which I have d for the past ten years with great satisfaction, particularly in e hemic and nutritive disorders of female Poe -— 4 Tuesday, September 22 Monday, September 21 264 DAYS PAST 101 TO COME June25, 1902. Dr. Luis del Rio, Contieras, Jaen, says: ‘“‘T have been highlysatisfied with the results obtained with PeptoMangan (Gude) in twocases in which it was tried. Ibelieveit is indicated in all conditions of bodily waste, whether producedby infectious diseases, anemia, excesses, etc. Ishall certainly lend my humble support to the preparation in all cases in whichit is indicated.” 4 —_ ty oA. ae \ 4 {+> A ry ¢ AX fi \ 265 DAYS PAST 100 To COME Dr. Manuel Botano, Physician in Chief of the City Hos- pital, says: ‘‘Your specific Gude’s Pepto-Mangan, with which I have been ex- perimenting, meets all the therapeutic requirements of a rational treatment of anzemias and dyscrasias, In myopinion, it has an advantage over other preparations of iron, in that it does-not tax the stomach, norgive rise to intestinal disturbances (constipation, diarrhoea), Its absorption is evident, from an experience I have had with itina case treated at the City Hospital suffering from cloroanemia, Blood counts were made by me before and after the administration of Pepto-Mangan (Gude), and revealed a considerable increase in the number of red corpuscles and a decrease of the white ones, after the taking of three bottles. As the above statement summarizes the valuable properties of yourpreparation, it is unnecessary to specify the diseases for which it is useful, Wednesday, September 23 266 DAYS PAST 99 TO COME In the Clinical Report ‘A Few Suggestions on the Treat= ility in Women,’’ by W. 0. Davis, Il. D., r,and published in the September issue, nternational Journal of Surgery, these “Tf the patient can stand it there is no better way of stimulating the nervous system than by cold douches or the cold pack, followed. by brisk friction of the skin, preferably on rising in the morning. For the anzmic a chalybeate should be selected which will not irritate or disturb the digestive organs, as these patients often suffer from constipation and dyspepsia. For this purpose I prefer Pepto-~ Mangan (Gude), which has the advantage of palatability, of being rapidly absorbed, and of exhibiting its beneficial effects upon the blood in a short time.” Thursday, September 24 98 TO COME 267 DAYS PAST William Edward Fitch, M. D., Savannah, Ga., in his paper, “The Pubescent and Adolescent Periods of A r rola WXy c ‘ . Girlhood,’’ appearing in Annals of Gynecology and Pediatry, Boston, Mass., August, 1902, says: “The only medicine ordered was Pepto-Mangan (Gude) three times daily. After the first month there was a noticeable change and after three months she was so entirely recovered that she reentered school, from which she had been absent for twelve months. Friday, September 25 268 8 DA DAYS Pp PAST ii 977 ‘TO COME July, 1902 From ‘‘Indiana Medical Journal :’ A woman of highly nervous temperament, cultured and refined had passed through herfirst confinement in May, the laborbeinga ery difficult one and resulted in a still birth. She grieved very much, and although fighting bravely against her depression of 4 o by autumn she became very neurasthenic and anemic. She had morbid fears, frequent flushes and some menorr hagia. She we a bed anc rive 11)t ~~. an : : Land given Pepto-Ma ngan (Gude) and 1 strychnia uph in grain 1-30t. i, d., and recovered rapidly.” ; Vy ayers September 26 269 DAYS PAST 96 TO COME . George Mosse Norton, Savannah, Georgia. In closing his Clinical report appearing in the Virginia Medical Semi-Monthly, July, 1902, says: “J am justified in asserting that in my therapeutic trials witl 1 Gude’s Pepto-Mangan I obtained all that can be rationally demanded. And [ far aser consider myself warranted in stating that in viewof the unquestionable necessity of ferruginous medication in certain troublesome constitutional affections this preparation acts as a most efficient and useful auxiliary to our therapeutic armamen tarlum. Sunday, September 27 270 DAYS PAST Monday, September 28 95 TO COME AST )4 December 10, 1901, November % Dr. Poths, Oberursel, writes: S. A. Long, I 1. D., New York City, says: Besides in cases of chlorosis the favorable effect of your Pepto- of n (Gude) was particularlystriking in nervous dyspepsia with tine’, "2 » ) ‘eceived a bottle of your Pepto-Mangan (Gude given a thorough trial, and the same has come up to my tion. Therefore, be assured ; ime at every opportunity .’ : that I will cheerfull ‘OME Tuesday, September 29 Wednesday, September 3 DAYS PAST 273 DAY 93 TO COME In the convalescent stage of “‘La Grippe” and other diseases Gude’s Pepto-Mangan is indicated as a general tonic and recon structive. 4 ) COME Dr. B. B. Edler vy. Wehrenalp, Teesdorf, Austria, says 7 , 4 ce ‘In reply to your favor of the Sth inst., I have the honor to in _ It has been demonstrated by such German scientists as Bunge, Hamburger, Schmiedeberg, and others, that of the different prepara- fe 1 OU SAS. ur Pepto-Man; ae Lrequent Much SUCCESS, ANd LAL il tions of iron, only the organic form can be absorbed and assimilated in any appreciable quantity; that only organic compounds of iron are taken up and make hemoglobin. The only preparation of iron possessing these qualities is Gude’s Pepto-Mangan, an organic solu tion of iron and manganese, as manufactured by Dr. A, Gude & Co., Chemists, Leipzig, Germany. ; — Thursday, October 1 AMA Nave > CA ; 214 I AYSI AS r 9 1 aA Friday, October 2 « A TO COME RICH RED BLOOD main desideratum in many cases ; richnessof the is richness or blood he circulating fluid in those important basic elements of vitality rlobin and oxygen, Pepto-Mangan (Gude) infuses this desirable mess in eases of anzemia, chlorosis, amenorrhoea, dysmenorrhea, rickets, Bright’s disease, etc., by furnishing these necessary heemo- slobin-making and oxygen-carrying elements—iron and manganesein aform for almost immediate absorption. Both repeated ‘blood counts” and clinical experience go to prove this statement. Pepto-Mangan (Gude) is put up only in bottles holding 3 xi. Prescribe original packages, and thus avoid substitution. Neversold in bulk. Samples and literature upon application. if 4 \ - 275 DAVS PAST , 90 TO COME Paes ‘‘T have used Gude’s Pepto-Mangan in a number of seemingly discouraging cases of anemia with the best and results.” most flattering Saturday, October 3 S PAST 89 TO COME June 4, 1902. Dr. Leopoldo Auz Feijoo, Lugo, says: ‘Tp to a recent time I had only used thesoluble formsof iron, as > per-cl and the insoluble forms, as reducedir on, but never 1 to gan (Gude) combination prepared by you. I amnow in a position tell you that I have used it with rapid and positive effect in aerate after hemorrhages, and in typical chlorosis. In s the ohults have been excellent. Your preparation posthe a ntagge of being pelatable and patients like it.’ f Sunday, October 4 YO COME 277 DAYS PAST Georse G. Wan ‘Sclinicks M.D., New York, in his clinical report, ‘‘The Diseases of the Blood in their Relation to Surgery and their Treatment,’’ says: ‘In twocasesof facial erysipelas in girls, seen at St. Vincent de Paul Asylum, and in a number ofinstances of cervical adenites, the blood count and estimation of hemoglobin were rapidly improved under the use of Pepto-Mangan (Gude). In rhachitic children it has given me muchsatisfaction. Duringthe course of treatment of a boy upon whom I did a double osteotomy for bowlegs, the blood count increased from 2,844,000 to 3,842,000 in four weeks, during whic h this pre paration wasgiven before> the operation. Po gg £ CY 4 Tuesday, October 6 Monday, October 5 YS PA , eae es nM SEERCOMRIT 87 TO COME ; SARs rs Ah wren re riasee sateen Mer -Fuvayrh Mr; Ca says: Alananticin Va., TMchaibe. | [lcGuire, Alexandria, Dr. Hugh introduct ion of ( tude s P¢ pto Mangan alarge number now use it exclusively when indicated.” TO COME ee ee 86 : August 10, 1901. Se ire wecie eli itheshetin, Eade eas: “Eversince I have become acquainted with Pepto-Mangan (Gude) ing ng to parations cla t be neutral or organic solutions of man(as peptonates) have been put upon the market. | i the subject I have taken pains to give cal test and have found none of them to y claim, andall of themgreatly inferior to Dr. Gude’s ticle. Theoretically, Pepto-Mangan (Gude) should be an ideal combination for administering manganese andiron. Its practical ‘esults in my hands have, however, been greater than theorypro- Sled, Ni SLU L have given it the preference over similar medicines which never [haveg " Une iy gaveme as good service. 4 & Wednesday, October 7 280 DAY 85 TO COME April 1, 1901. . Vogelsang, St. Louis, Mo., says: Pepto-Mangan (Gude) far superior to anything| lofits kind. Ihave prescribeda considerable quantity t recently and in each case have found entire satisfaction. i iave also used Gude’s Pepto-Mangan in severe cases of debility ervousness and complete collapse, and have obtained the ent results with it. I can conscientiously recommend it ation of its kind I have ever used, and to prescribe it in the future as ] have assure you freely done Thursday, October 8 281 DAYS PAST ‘| 844 TO T COME August, 17, 1901. Karl von Ruck, B. S., M. D., Journal of Tuberculosis, Asheville, N. C., writes: ag ons ide’s of Gude’s ority of first tl irst to recognize ‘ecognize the superiority ‘‘T was one of{ the Pepto-Mangan over all similar preparations at the time of its eee piety in this country, and I have found no other since ee vi owe care to exchange it for in my practice. FE opie Meneey ad is : ; employedin , ire it itiin the he invah Saniregularly all cases. that require inyah Sani tarium and with uniform success.” 4 __ Friday, October 9 #54 DAYS PAST — : — : Saturday, October 10 83 To “= June6,1902, _ i a J > e Dr. Hipolito Toves, Burgos, says: “L have prescribe ( scent frontha I ibed Pepto-Mangan (Gude) in the ae So of vee standing, who sase of a conval showed pe Sg 0 sis. > res wasSo beneficial tl 31 7 i Se Ss : aoe preparation & proper wi Sa td e streng h. a, diet the patient nicht on soon he success was hichly satisfactory.” Pooh: odhee lost Pag ttae 4 i 283 DAYS PAST 82 TO COME Commercial solutions of Iron and Manganese are made with the aid of Acids or Alkalies, and notablythe latter ; that is they are held in solution in the presence of acomparatively large quantityof Caustic Soda, which neutralizes, to a certain extent, the Hydrochloric Acid in the stomach, and liberates Oxides of Iron and Man- ganese. The latter, through the action of the Hydrochloric Acid of the gastric juice, are converted into chlorides of these metals, and thus cause a caustic action uponthe gastric mucous membrane. This has been proved by Prof. Bunge, as shown in his very able article read before the Congress of Medicine at Munich, 1895, Sunday, October 11 Ss PAST > Monday, October 12 $1 TO Com: From the ‘St. Louis Medical and Surgical Journal.” ‘It was the work of Gude whicl 1 elaborated what is as Gude’s Pepto-Mangan, a remed y Conce rning whose a1 action no doubt exists.” riginal communication from A to day know1 positive 285 DAYS PAST Dr. : Wm. Menger, Late 80 : Z House Surgeon to Hospital, N. Y., Says: TO Beth COME == Israel ben: I am at present using Pepto Mangan H, Ohmann-Dumesnil. M. D. = = — Gude) in a case of cachexia vhich is due to carcinoma of uterus. [ wish to tell you of gratify nggr results which I :} 1ave obtained from same in the past two weeks They are remarkal The woman has left her bed, and has an ex oa appetite, fa.very little i i ellent pain. about a month ago.” rTThese symptoms y is were were quitese quite severe _ Tuesday, October 13 é —_—— Wednesday, October 14 > COME June 23, 1902. : : ce a wants Dr. Manuel de la Casa, Gi anada, Spain, says: wT have tried Pepto-Mang‘an (Gude) in-a case of atonic dyspepsia and in another of anemia. In both it has proved to be a good aperient and an excellent blood-builder and tonic. very desirable for all cases of atony and organic debility, even whenof long standing,” no ~ D> 287 DAYS PAST 78 TO COME Dr. Hugo Summa, of St. Louis, in an article in the New York Medical Journal, reports having treated 34 cases with Pepto-Mangan (Gude), partly cases of chlorosis and partly cases of secondary anzmia, occurring chiefly after sub-acute malarial and typhoid fever. Two cases of chlorosis an:t four of secondary anzmia he gives in abstract, in all of whom there was great improvement or complete recovery’ Thursday, October 15 288 DAYS PAST NOTE. Friday, October 16 77 TO COME 289 DAYS PAST Dr. C. A. Von Ramdohr, in a Clinical Report Read Before the New York Academy of Medicine, says: tT What weclaim for Pepto-Mangan (Gude), and the same has never’ been refuted, is that the metals, iron and manganese, exist in an rgano-plastic form, the solution being positively neutral in reac- ‘To further guard against making any allowance to my enthusiasm, I had the blood of some patients at the New York Post Graduate Hospital tested by Dr. H. T. Brooks, the director of its pathological laboratory, and similar tests at St. Mark’s Hospita} made by the pathologist, Dr. George Lindenmeyr. Some cases were kindly loaned mefor observation by Dr. .H. J. Boldt, Dr. J. R. Nilsen and Dr. Carl Beck, to all of which gentlemen [hereby once more acknowledge my indebtedness. The preparation used in all cases was the peptonate of iron and manganese, made according to Dr. tion. The metals are held in perfect solution as true peptonates, being produced by a process heretofore unknown. This preparation, Gude’s Pepto-Mangan, when taken into the stomach undergoes no chemical change whatsoever. Being practically predigested, it is readily absorbed by the mucous membrane of the stomach, the process of assimilation is easy, and the metals are taken upby the blood immediately. is Us 76 TQ COME ME Gude’s formula, and knownforshort as Pepto-Mangan (Gude).” Ltt Ved d 4 Saturday, October 17 290 DAYS PAST 75 "O COME April 21, 1902. Dr. Shick Simon, Budapest, Hungary, writes: “TI employed your Pepto- Mangan (Gude) is a case of marked anemia in a girl 19 years old. In this case all sorts of iron preparations had left me in the lurch, 1] then resorted to your preparation, less for the reason that I had confidence in it than because I was really curious to learn whether the prove of service when the use of others had been remedy would preparation exceeded decidedly all my expectationsfruitless. Your has recovered almost completely since commencing . The patient its use from her protractedillness, and her appearance has greatl y changed for the better.” Sunday, October 18 291 DAYS PAST 74 TO COME From the Hebrew Orphans’ Home, Atlanta, Ga. ‘*The results which we have obtained bythe use of Gude’s PeptoMangan with some of ourlittle patients are so excellent that we have decided to continue its use, the benefit of this admirable preparation being so markedandpositive. } r] ba ) a/ Monday, October 19 292 DAYS PAST 73 TO COME COUNT THE RED BLOOD CELLS afara < © > both | before andaf ter. treat ment ifif you want an accurate scientific ee of theeffective blood-building power of bi tah eas mucous membranes of eye and lip Pepto-Mangan (Gude) if you want a positive : ree a demon copes > oe C 4 c c L 5 . stration of its value as an oxygen-carry ing, haem ¢ n-nr 08 ° ae rhe au> ing, chaly ~ beate tonic 7 a : 5 in anzemia, : ‘i chloros is, or blood : _ Ov cod asl from any cause. Wewill be glad to send sample or practical experimentati re ‘with descripti it . and and reportssofof ‘tk ‘blood oa i nea y iarge ao numbe co rofe careful salle ly ol oe Served é cases.s. S Shall eyo Shs we do so? so?a To assure ssure proper ASS ie Che r e, filli illing of: prescr scri ipP nes mae ottles Px (Gude) in orie tions, order Pe ptc-M never sold in bulk, angan Tuesday, October 20 293 DAYS PAST nt PR ant ee aa 72 TO COME Extract from a paper read before the Amstetten section of the [ledical Association of Lower Austria, by Ed, Hoenigshmied, M. D.: ‘“The preparation of Dr. A. Gude, chemist, of Leipsic, (Gude’s Pepto-Mangan), undergoes no chemical change in the system, but is completely absorbed and taken up bythe blood. ‘‘? have empl other preparations experimentally, but with none have I achieved even approachablysimilargood results.” 29 4 Wednesday, October 21 DAYS PAST Thursday, October 22 71 TO COME 295 DAYS PAST April 19, 1902. Dr. Wolf Spatz, Surgeon to the Royal Hungarian Railway City Physician, Csorna, Hungary, writes: e e e * Dr. Emory Lanphear, St. Louis, Mo., in three surgical cases, found a blood count averaging 3,286,666 . ea‘That ne atI Ll:aza mas : h please as d with 7] your PePept your pto-Mangan ng i (Gude) can be seen Irom the fact that your preparation is pharmacyat this place, and is prescribed by me kept in stock in the Not I alone but also mypatients are much satisfin large quantities, ied.” “ Wf f oD 70 TO COME before treatment, a number corresponding veryclosely with that found by Dr. von Ramdohr. He kept his patients under treatment for a period averaging over thirty-seven days, however, and then Ie ya Friday, October 23 296 DAYS PAST Saturday, October 24 69 TO COME 68 TO COME The Vital Bank Account of the neurasthenic undergoes a constant depletion, Frequent drafts upon the reserve store of nervous force reduce the available balance of energy from dayto day; if Nature’s balance is not forti fied by deposits of vitality, physical bankruptcy is the inevitable result. The primal essence of vital force and energy consists of good, healthy, well-oxygenated blood. Pepto-Mangan’ (Gude) contributes the essential haemoglobin, and aids in the formation of red globules by supplying neutral organic iron and manganese in a condition for immediate and complete assimilation. It thus quickly “‘makes good” the existing deficit and assists the neurasthenic to maintain and increase his vital bank account. F From the ‘* Medical Mirror,”’ January, 1900. ‘‘Imitation is not only the sincerest fl attery but endorsement as vell. The numerous efforts at imitation of the Gude Pepto- Mangan that have beenn indulged in simply emphasize the importance of the members of the profession seeing to it that only the Gude’s Pepto-Mangan is prescribed for their patients.” Sunday, October 25 298 DAY PAST 67 TO COME hs Dr. Yon Lom, Halle a/d. Saale, says: ‘Tam glad to say that I have for a number of years employed Pepto-Mangan (Gude) with good results notonlyin chlorotic girls, but also during convalescence fromseverediseases and loss of blood. "he best proof of mysatisfaction with the preparationis that I resort to it exclusively in appropriate cases.” ya, aaa ge ] | ; 0 ey Re y rf Monday, October 26 299 DAYS PAST 66 To CoME Dr. Robt. A. Reid, in “Massachuset ts Medical Journal,’’ says: ‘To sum up the advantages of Gude’s Pepto-Mangan it is easily sted, indeed it seems to aid digestion, is readily assimilated, is hout astringency, does not constipate or stain the teeth, and is ertainly more prompt in its effect than any preparation of iron I ever used.” Wednesday, October 28 Tuesday, October 27 300 DAYS PAST 65 TO COME Dr. Julius Heitzmann, Vienna, Austria, writes: ‘Jn almost every instance I observed within a short time increase of appetite, improved nutrition, healthier color of the face, and insrease Of weight. Iwas surprised to learn how much morereadily the Pepto-Mangan (Gude) was taken than similar preparations, without ill effects even after protracted use.” 301 DAYS PAST 64 TO COME From St, Louis Medical Era, ‘*A’Few Words About Sube stitution.’’ Oneof the hardest problems an honest pharmaceutical house has to contend with is substitution. A physician with a reputationhas no meaner foe than the substitutor. But perhaps the poor patient suffers most of all, for oft-times his very life may be jeopardized by Z Thursday, October 29 302 DAYS PAST 63 TO COME August 16, 1901, Dr. Ruedelf, Rhaunen, says: zarding Pepto-Mangan (Gude), it affords me muchpleasure to inform you that I prescribe your preparation almost daily. It com- bines palatability, which is of especial importance in pediatric practice, with most remarkably promptefficiency.” Friday, October 30 303 DAYS PAST 62 TO COME H. Edwin Lewis, M. D., Burlington, Vt., in the “Vermont Medical Monthly,’’ under the heading“Irregular Menstruation in Young Women Due to Anzemic Condi- sk eG eel HONS, a Says: ut since manganese has grown in fay preparation has been submitt In every way it has proven ltselt ; preparation known as Pepto-Mangan.”’ ljuvant to iron, cal profession, [refer to Dr. Saturday, October 31 304 DAYS PAST 61 TO COME Deering J. Roberts, [. D., Nashville, Tenn., closes his paper which appeared in ‘‘The Southern Practitioner,’’ with the remarks: ‘‘ Neither the hemoglobin nor the red corpuscles were estimated by laboratory methods—nor was there any need. Each case, its progress and its results, have been so plain that ‘he whoruns may read.’ ‘I could cite other cases of both primary and secondary anemia in which I have had equally good results, but as they were not so marked, so severe and so critical, I will desist, concluding byfully s concurring with the statement that is made, that ‘this preparation, Gude’s Pepto-Mangan, when taken into the stomach undergoes no chemical change whatsoever,” ‘ Sunday, November1 305 DAYS PAST 60 TO COME Extract from Report of Dr. S.Ascher, Hamburg, Ger= many. ““Gude’s Pepto-Manganhas been tried by meand a fewcolleagues in various diseases associated with a depreciated condition of the blood, altogetherin eighty cases. The remedywas always,well borne, digestive disturbances were never observed, the marked symptoms of headache, vertigo, palpitation of the heart, and loss of appetite were improved within a few weeks.” Monday, November 2 306 DAYS PAST 59 TO COME FOR ANZEIMA, CHLOROSIS, AMENORRHEA, DYSMENORRHGA, PE PTO= CHOREA, RICKETS, BRIGHT’S a DISEASE, and a GENERAL TONIC Tuesday, November 3 307 DAYS PAST GUDE’S MANGAN and RE-CONSTRUCTIVE., Specify Gude’s (contents of an original bottle = xi.) and thus avoidsubstitution. 58 TO COME Dr. Stuart [icGuire, Richmond, Va., says: ‘‘I amusing your preparation extensively in myprivatepractice, and from the standpoint of a clinician can endorseit heartily.” p f Wednesday, November 4 308 DAYS PAST 57 TO COME “ ANAEIIIA is the sneakthief of all diseases.” Itstealson insidiously, frequently varrying in its wake the beginnings of disease of more serious import. ‘‘Oppose beginnings,” is an old and true proverb, PeptoMangan (Gude), by furnishing the blood with an immediately absorbable combination of Organic Iron and Manganese, increases the oxygen and_hemoglobin-carrying powerof the Red Corpuscles and thus nourishes all the tissues of the body. Itshould be n cases of Anemia, Chlor-anzemia, Chlorosis, Rhachitis,employed Neurasthenia, or in blood impoverishment from any cause. To assure proper filling of prescriptions, order Pepto-Mangan (Gude) in riginal bottles (3% xi), It’s neversold in bulk, et Thursday, November 5 <09 DAYS PAST 56 TO COME Dr. Ludwig Pohl, City Physician of Vienna, Austria, commenting upon the therapeutic value of Organic Iron in the Septemberissue of ‘‘Aerztlicher Central Anzeiger,”’ Vienna, Austria, makes use of these words : ‘‘Of much greater importance is the circumstance, however, that in numerous diseases of the blood occurring in connection with the lymphatic and blood-making organs I have derived excellent results Saturday, November 7 Friday, November 6 310 DAYS PAST 55 TO COME 311 DAYS PAST 54 TO COME Extract from the report of the Committee on Infringements. National Wholesale Druggist Association Meeting at St, Louis. ‘¢ St. Louis Medical and Surgical Journal,’’ A. H. Ohmann-= ‘‘ There is a hidden infringer who never appears outside the pale of darkness ; that is the dishonest man whoinfringes by substitution. Such a man for the sake of afew pennies extra profit wilfully defrauds the physician and patient at a time when health andlife are **One thing which I have noted is that in the anzemic conditions not infrequently observed in so-called tertiary syphilis, Gude’s PeptoMangan exercises a most satisfactory and beneficial effect. This enables the patient to undergo a more thorough treatment andhis troubles seem to yield to specific medication. ‘There is no doubt in my mind that as the goodeffects of this preparation, as an adjuvant in the treatment of syphilis becomes better known the more general will be its use.” in the balance, ‘* Note : Prescribe an original and avoid substitution.” (7 xi.) bottle Gude’s Pepto-Mangan Dumesnil says, regarding Gude’s Pep.o-Mangan, in Syphilitic Anzmia: J Oyrr GT tifireg ry ’ A ayZ ; ) os: f Cire oy tines Var a A-t x ><—f L /, / - : Sne Sunday, November 8 312 DAYS PAST 53 TO COME TAKE A BABY ‘ subject rhachitis, or one whose nutrition is at a low ebb. Place a drop of thechild’s blood underthe microscope and countthe red corpuscles. Then put the same baby on Pepto-Mangan (Gude). ‘rom time.to time re-examine the blood and observe the rapid and progressive increase in the red cells coincidently with an obvious improvement in the child’s color and appearance. One such case will convince y yu that Pepto-Mangan (Gude) is a true ‘ bloodbuilder.” To assure proper filling of prescriptions, order PeptoMangan (Gude) in original bottles (% xi.). It’s never sold in bulk. Monday, November9 313 DAYS PAST 52 TO COME PEPTO-MANGAN IN RHACHITIS. Adolfo Fasano (Archivo Internazionale, 1° Maggio, 1899,) reports on the results obtained in the treatment of a trial of ten cases of rhachitis with Pepto-Mangan (Gude). Five were cases of medium severity while three were quite severe, having already developed craniotabes. The results were excellent. In those of medium severity nothing else was employed save an invigorating diet. The effect was a keener appetite, improved bodynutrition and the production of better blood, and as these appeared the pathological conditions retrograded, Tuesday, November 10 314 DAYS PAST Wednesday, November 11 51 TO COME 315 DAYS PAST PEPTO-MANGAN(GUDE) John S. Moreman, M. D., editor of the Medical Progress, writes: s rapidly and easily assimilated. Produces a rapid increaseof red rpuscles in the blood; is perfectly miscible with sherry, milk or water; pleasant and agreeable to the taste; gives appetite and etct cain children take it readily, it can also be adminDoesnot affect the teeth. disturbance. eo te 50 TO COME “Tn the treatment of secondary anemia attending abortion, which character of cases have been most plentiful since my connection with the Maternity Hospital, I find Pepto-Mangan (Gude) uni formly good. In somecases the blanched lips, pale face, and other symptomsof anzemia fled away with surprising rapidity. A special feature that commends Pepto~-Mangan(Gude) in the treatment of the anzemia of lying-in women is that it does not derange the secretions as is the case bedae iron preparations.” Does not constipate or produce gastric “> 1 fei ¥) hi [ v IMA y (Vor. 22D pL C f L . Sans = Fad corset cee Cy 1 Lihof~ (Lh now Yer) Li-ga cof s Z 7. 1-1 Ig 1 5 TAG; Xan j Thursday, November 12 316 DAYS PAST 49 TO COME George G. Van Schaick, I. D., after investigation carried on in the French Hospital and St, Vincent De Paul Orphan Asylum, New York City, closes his report with these remarks: ‘‘The writer has altogether made, or caused to be made for him, blood counts and estimations of hemoglobin in fifty surgical cases in which Gude’s Pepto-Mangan was used. In his experience of the last few years he can recall only onepatient, a nervous and capricious voung woman, with whom it failed to agree.” Ar A Pa \2 7 2 Friday, November 13 317 DAYS PAST 48 TO COME August 17, 1901. Dr. Archibald Church, editor Chicago Medical Recorder, Chicago, lll., writes: ‘‘Gude’s Pepto-Mangan has proven for me a very superior ferruginous preparation in_a large variety of anemias and depraved physical conditions. Carefully observed cases of simple anzemia have responded to its effect with a minimum of the disadvantages that usually attend the administration of iron in adequate doses.” Saturday, November 14 318 DAYS PAST 47 TO COMB Sunday, November 15 319 DAY PAST a Dr. Eperon, Lausanne, Switzerland, writes: “J prescribed two bottles of your Pepto-Mangan (Gude) which you had the kindness to place at my disposal, for a young relation who tolerated with difficulty the other iron preparations. made an excellent recovery under this treatment.” She has = _— 46 TO COME —_— ee e — i BLOOD POVERTY means a diminution of the number of the fundamental red corpuscles ; a reduced percentage of oxyg en-carrying hemoglobin, and as a consequence, a diminished resisting power against more serious disease, Pepto-Mangan (Gude) supplies It furnishes organic iron and Manganese to these deficiencies the blood elements, increases the hemoglobin, and restores to the blood its normal germicidal potency. Pepto-Mangan (Gude ) literally ‘‘ builds blood” in cases of anzemia, chlorosis, amenorrh ea, rickets, Bright’s disease ete. To assur e the proper filling of your prescriptions, order Pepto Mangan (Gude) in original bottles (5 xi). It’s never sold in bulk Monday, November 16 320 DAYS PAST 45 TO COME Dr. Edwin Williams, Memphis, Tenn., reports in ««Memphis Lancet,’’ a case of Chorea, treated successfully with Gude’s Pepto-Mangan. “Boy, aet. 11, only child. History of rickets in early childhood, poor physique, slight anemic murmur at base of heart. Blood examination showed 3,600,000 red blood corpuscles to the cubic millimetre and the leucocytes diminished in amount. Began to havefits of depression about six weeks before I saw him, and a week before being brought to my notice had marked choreic movements. When I first observed him the movements were very noticeable and they were constant and irregular.” Coe. 321 3 Tuesday, November 17 DAYS PAST 44 TO CoME Dr. Matthey, Neuchatel, Switzerl and, writes:_ . ‘It gives me pleasure at this time to inform ou that lar i i eae pees of your Pepto-Mangan (Gude), which jeehet Eee requently during sever al years in certain cases of ee November 19 noe November 18 322")DAYS PAST 323 DAYS PAST 43 TO COME Abstract from paper by Dr. W. Krauss, ‘Pathologist.to St. Joseph’s Hospital, Memphis, Tenn, Subject: «Note on the Treatment of Anzmias:’’ published in ** Memphis Medical Monthly.”’ BLOOD GENESIS. The formation of a rich nutrient circulating fluid. Blood which shall contain an abundance of red corpuscles of the necessary structural and physico-chemical integrity. How to ‘‘ build” such blood is an ever present therapeutic problem for the physician to solve. Pepto-Mangan (Gude) is a powerful blood-forming agent ; it induces the generation of haemoglobin, the oxygen carrying constituent of the blood ; it is a genuine hemoglobinogenetic. It feeds the red corpuscles with organic iron and manganese which are quickly and completely absorbed in cases of anemia from anycause, chlorosis, amenorrhea, dysmenorrhcea, chorea, Bright’s disease, etc. To assure proper filling of prescriptions, order Pepto- Mangan (Gude) in original bottles (% xi.). © It’s never sold in bulk. TO COME ‘‘In Gude’s Pepto-Mangan we have astable and palatable preparation, uniform in composition and therapeutic effect. I have used good results.’ some five years Kn 8 -~Mangan Senneade) Pepto- J UL Ve 7AnF == iSos £ —— eee fre d7 Li. - We pho A MO Au 2 x Tele, Fasst i ny Friday, November 20 324 DAYS PAST Saturday, November 21 41 TO COME 325 DAYS PAST 40 TO COME Dr. Lucchini, Cureglia pres Lugand, Switzerland, writes: September 11, 1901, “T would assure you that yourblood-builder BootsMasigas (Gude) has given me very good results in anemia, chloro-anemia, and in the first>stages of tuberculosis.” Tay to Al ff olVar, 7 NX, Dr. Winslow Anderson, editor (Pacific Medical Journal, San Francisco, Cal., writes: oh Hed ‘For several years we have used a considerable quantity of PeptoMangan (Gude) in ourhospital and private practice. For anzemia, chlorosis and general debility with a paucity of red blood corpuscles and hemoglobin, we know of no better aai than the free use 4p of Pepto-Mangan (Gude). a Je} picked (Lo Par SITE ?'7 Soot Rive 9 Lo ire in Bids Ligaen meee 2 4 a ra i YAY , 0‘ioe OL oo o ay O ts! ) bee. ALC Oye Sunday, November 22 326 DAYS PAST Pepto-Mangan (Gude) inoriginal bottles. iad 327 DAYS PAST 39 TO COME HOLD FAST TO THAT WHICH IS GOOD! When a physician learns by experience that a certain remedy produces positive results, he becomes familiar with its indications, limitations and therapy, and therefore wants no substitute or makeshift dispensed when he prescribes it. When a physician has for a long time prescribed Pepto-Mangan (Gude) as a blood builder in anzmia, chlorosis, rickets, amenorrhca, dysmenorrhcea, chorea, Bright’s disease, etc., he knows byexperience that itis a standard of therapeutic worth and wants noother. Butsometimes the patient don’t get it. To assure the properfilling of your prescriptions, order zy Monday, November 23 It’s never sold in bulk. Dr. Fumasoli, Comprovasco, writes: “I will state that your blood-builder Pepto-Mangan (Gude) which I have prescribed for several years, is an excellent preparation in chlorosis. It is easily tolerated even by a feeble stomach, and it oe most gratifying results in the course of several weeks treatment.’ ¢ [Pe Of aaanios A, 4o nL of A) py Wf oy Tuesday, November 24 328 DAYS PAST Wednesday, November 25 37 TO COME 329 DAYS PAST Dr. V. E.Watkins, Asst. Surg. U. S. A., U. S. Gen. September1, 1901. Hospital, Ft. McPherson, Ga., says: ‘‘T desired your Gude’s Pepto-Mangan for a patient convalescent from typhoid and malarial fever, in whom the resulting anemia was pronounced. I take pleasure in stating that the resultsin this case were entirely up to my expectation, being already familiar with the effectiveness of your product in such andother cases.” _ y - 3 a 4 /y a ae 5a See 36 TO COME Dr, Carlos E. Kohly, Havana, Cuba, says: ‘About five years ago my attention was directed to your excelle nt preparation of Gude’s Pepto-Mangan by one of my confreres who had it prescribed for him by a prominent physician of the States. It has been myprivilege since then to prescribe your preparation for a great variety of cases, those depending mainly on a restora tion and strengthening of the blood—such as anzemia, chlorosis, etc., and I must confess that it is my mainstay in such ailments, and I pre- — la scribe your preparation with a positive confidence of success. In the treatment of malarial fevers so commonin our country, I have foundnothing to equal your preparation which acts as a tonic appetizer and a general reconstructive agent.” as J 42svnmre7, ee 5 Lay 4 A YY 4 ‘ 7 L tpWrenn Be erred See a pZ =, pe potea2, Oe , Ltn & <i fro 7 A- UKs te > ~ Friday, November 27 ee November 26 330 DAYS PAST 331 DAYS PAST 35 TO COME From Wisconsin Medical Rana Bab 1901: *¢ Anzemic School Children:—Anannoyingclass of patients which every practitioner has is ansemic school children whose appetites are poor and who are nervous andirritable. ‘¢(Gude’s Pepto-Manganis a verysatisfactory medicament in such cases. December28, 1901. Dr. K. Hugel, writes: Railway Surgeon, Schongau, Germany, “T have employed Pepto-Mangan (Gude) in the case of a young woman, 24 years old, who in consequence of a severe loss of blood due to gastric ulcers one and one-half years ago, had become extremely anze sie The ordinary iron preparations producedpainsin the stomach, which was probably the seat of cicatrices, and therefore could not be employed. I have the plcoeute to inform youthat your preparation wassplendidly borne by the young lady aud pro- eA ede duced excellent results.” Gra carmengeeettiag ‘ ——— Co | ee ae eeae “un hee J f a 34 TO COME Sunday, November 29 333 DAYS PAST 295 32 DAYS PAST 32 TO COME December17, 1901. Dr. Academyof Medicine, a paper subsequently printed in the New York [ledical Journal, in which he gave the results he obtained after Gynaecological operation by the administration of the Pepto-Mangan., Dr. Herz, Liebingen b. Frankfurt, Germany, writes: ‘‘Your Pepto-Mangan (Gude) has always afforded me goodresults in the treatment of anemic women. Its clear appearance, agreeable taste and absence of any unpleasant by-effects facilitate materially its administration.” His observations being controlled byblood count andestimation of hemoglobin, are of distinct scientific value. In eleven patients this remedy was administered during a period averaging a trifle over twenty-two days. The blood count in all these patients averaged 3,367,727 red blood corpuscles before the administration, and had risen to an average of4,272,363 at the end of the period mentioned. a PAK y) Monday, November 30 334 DAYS PAST 31 TO COME Extract from Editorial in ‘‘ Dominion Medical Monthly.” ‘Take for instance, Pepto-Mangan (Gude), the value of which almost every medical practitioner is now familiar with. The physiian has learned from experience just what this particular remedy will accomplish ; he knows its advantages, limitations, indications and dosage, and prescribes it in properly selected cases with full onfidence in its action and effect. Just here, however, the physician loses control of his ‘working tool’ unless he is positively certain that his prescription will be filled exactly as specified.” i} } lLyote 4 //} Cer ey ~ QO a Vpn aye A x Tuesday, December 1 > 335 DAYS PAST 30 TO COME Dr. Julius Heitzmann, Vienna, Austria. In his paper, ‘‘The Employment of Iron Preparations,” uses these words: ‘‘ Pepto-Mangan (Gude) usually mixed with some water, is prescribed in doses of two orthree dessertspoonfuls, increased to as manytablespoonfuls perday. Anespecially agreeable manner of administration is by addition of cold milk, which then assumes a light chocolate color and has an agreeable taste. Prescribed in this form we obtain fromthis preparation evérything that could be expected from a remedyfor anzemia.” 1) —= _—— ae tf IL y $08, Wednesday, December 2 336 DAYS PAST 29 TO COME Abstract from Dr. E. C. Hill’s article ««How to Assist Young Girls to Womanhood,’’ which appeared in Thursday, December 3 337 DAYS PAST Dr. Hermann Metall, Assistant Physician to the General Polyclinic, Brooklyn Medical Journal July, 1902. that when hemoglobin is taken into the stomach it is changed by the acid there to hematin (causing the coffee-ground color of small gastric hemorrhages), which, according to Cloetta, passes down the alimentary tract without being absorbed. Vienna, Austria, in the concluding re= marks in his Clinical report appearing in the Medicinisch-Chirurgisches Central-Blatt, Vienna, Austr ia, January, 1902, says; “The use of iron in anzeemic and chlorotic conditions is, of course, a cardinal principle in therapeutics. In girls becoming See supply a deficiency of erythrocytes or hemoglobin, one mig = infer } at first thought that the best method would be to administer gemoglobin, that is, blood in some form. Chemistry proves, however, 28 TO COME ‘‘The histories cited will afford conclusive eviden therapeutic value of Pepto-Mangan (Gude). Unpleace of the high sant tant effects and disagreeable sequels: were NEVER observ concomied during the use of the remedy. Eructations, pressure in the stomach, and nausea were never noticed. In conclusion I would say that PeptoMangan (Gude) is a valuable andreliable blood-buildi ng remedy, which can be recommendedfor general use in appropriate cases,” 7} j ~ Friday, December 4 338 DAYS PAST 27 TO COME HUNGRY BLOOD; blood that is starved because it has not the capacity for absorbing oxygen; ,thin blood which has not been nourished; weak blood which has lost the power for replenishing waste and building new tissue. Thin blood makes a thin body. Feed the blood and you the body. If the blood is lacking in red corpuscles and emoglobin it needs rebuilding, that it may be capable of performing its task of reconstruction. 5 Pepto-Mangan (Gude) is a powerful regenerator of the blood. Microscopical examinations prove that itbuilds blood; increases the number of red corpuscles and hemoglobin in a remarkably short space of time. ata A A J / 1} 4 ( tA tre oO /f Saturday, December 5 339 DAYS PAST 26 TO COME Dr. George Mosse Norton, Savannah, Georgia, Ina paper entitled ‘Some points in the Pathology of the value of iron in the treatment of Anzmia Chlorosis’’ and appearing in the Virginia Medical Semi-Monthly, July 25th, 1902, cites the following 5 cases: CASE I. Prrnicrious ANzZMrA.—‘‘A man, aged 35 years, came to me in February, 1900, complaining of giddiness, shortness of breath on exertion, and general langour. His skin was of the peculiar lemontinge so often seen in these cases. The patient had not lost flesh, and, in fact, he thought he was stouter than formerly, Inquiry elicited the fact that he had had a family worry s mmetime previously, and that he had neverfelt himself to be the same man since. He had begunto feel weak and unable to exert himself, and his friends at the same time beganto notice his increasing pallor. The urine was high colored, but free from albumin. The ordinary causes of anzemia were carefully eliminated, and the case was diag- nosed as one of pernicious anzmia. Sunday, December 6 340 DAYS PAST 25 TO COME Dr. George Mosse Norton—Case I. Continued. An examination of the blood resulted in the discovery that its specific gravity was reduced. The corpuscles did not adhere in rouleau, and their number was greatly reduced, 3,400,000 per cubic millimetre; but what was most noticeable was their great variati on in form andsize, Nucleated red corpuscles werealso present; heemoglobin,.45 per cent. of thenormal. Arsenicin gradually increasing doses, in the form of Fowler’s solutlon, was given and continued tor some time, but with absolutely no good effect. At the commencement of this treatment the patient was keptin bed. The dietordered ceous. Iron wasthen administered, but with like was chiefily farinaresults. The patient was evidently getting weaker, Happening to mention the case to a friend, he advised meto try Pepto-M angan (Gude). It was givendaily with the best results for twoand ahalf months, A further examination of the blood showed that the corpuscles were assumin g their natural shape, and their number had increased to 4,500,00 globin to 78 per cent. of the normal: but the more 0, and the hemotangible andsatisfactory result was the condition of the patient, who was able to resume his work with me - ~y / 341 DAYS PAST 24 TO COME Dr, George Mosse Norton—cContinued. CASEIT. Prrnicious ANZjMIA.—“This case was interesting from the fact that the patient had been treated with salol afterthe failure of arsenic with a marked improvement, but unfortunately with a The patient was a woman, aged 38 years, who complained of faintness, palpitation, loss of appetite, extreme debility, and constant vomiting. The pallor of the skin was striking. The mucous membranes were pale, there was edema overthe malleoli, and there were some petechial hemorrhages on the lower limbs. An examination of the blood revealed the fact that the red blood corpuscles were greatly reduced in size and number, 3,200,000 per cubic millis Caw // : cays H+¢ ect Cs ¥ 4M VY a4 1 oy * -7 ben a freed nyfrom all his previous symptoms”, nee — i: : 2 LYA O41Ff ~— Monday, December 7 { 4 cA & aS ee Cae of ) @ y / x we, RL cu J Lar of Li fe iy Cb eres he ay? j Gs GAL Cy 4Af 7Ln fe Cok Thursday, December 10 344 DAYS PAST 21 TO COME Dr. George Mosse Norton—Case III. Continued. the spleen. As soon as placedin the hospital we madea blood nation, which showed the red blood corpuscles greatly reduce examidinsize and number, 2,850,000 per cubic millimetre, their great variation in form and size was quite noticeable. The percentage of hemoglobin was reduced to 40 percent. After regulating thesecr etions and alimentary canal, and prescribing for the malari of the liver The patient was placed upon tablespoonful doses of al poisoning. Pepto-Mangan (Gude), three times a day, anda stuffing diet of nutritious food, con— sisting of meat, broths, eggs, milk and Port wine. This treatment was contin ued for four weeks, when her condition became much improved, her skin cleared up, she gained in weight and appetite re- turned. She was ordered to the mountainsof Virginia, and took a supply of Pepto-Mangan (Gude) with her, and on her return, after a two months’ stay, an examination of the blood showed the following: Red blood corpuscles, 4,500,000 per cubic millimetre: percentage of hemoglobin was increased to nearly normal. Sheno w weighed 112 pounds, and was in splendid condition physically.” Friday, December 11 345 DAYS PAST 20 To COME Dr. George Mosse Norton—Continued. CASE IV. GrneraL ANZMIA IN A Young GIRL OF SIXTEEN YEARS.—:‘‘Whenfirst seen she was pale, thin, and badly constipated, There was almost constant headache, and she had but very little appetite, She first menstruated in her fourteenth beenregularforover ayear. The corpuscle count year, but has not was 3,000,000 to cubic millimetre. Gude’s Pepto-Manganin tablespoonful doses three timesa day after meals was givenfor a period covering four weeks. In two weeks after beginning the treatment has began to have some color in the lips, and from that time on rapidly improvedin all Symptonis, and now has no trouble except with the menstrual funct-— ion. The blood at last count, one week ago, was 4,000,000 cubic millimetre, Her weight increased during this time to 1 nine pounds.”? sles LL ay 5 ee en 7 A/ ; z t PF) oe iL gy 201 if phr-~24 y 1% AD j A, Cray AA en C/ Y 4 pared —— a LJ a f 7 \ 4 2 Cp Or / i f oI fle LLA _ s | ¥ * } a —¥ ; { 7 / 7 5 t TD of f i t bleit Ae ¢ &L f oe 1 atMhe2 Une ee Ce ew ' > aa Y os 5 y Ae, f Pt Ly aie 4 “CaN VD rs (vw Saturday, December 12 346 DAYS PAST Sunday, December 13 19 TO COME Dr. George Mosse Norton—Continued. CASE V. Young Lapy NINETEEN YEARS OLD, PRESENTED HERSELF FOR TREATMENT SUFFERING WITH MARKED CHLOROSIS.— ‘The disease was of several months standing—prominent among her symptoms was a general functional disturbance, togethe r with mental anxiety anda disinclination to work, to enjoyli fe, or muve about, marked muscular weakness, cardiac palpitation, breathing, loss of appetite, headache, vertigo, restless difficulty in , lessness, Patient’s family and personal history good; she and sleepstruated in herfifteenth year, but scanty and irregular. first men— There was marked pallor of the skin and mucous membranes, cardiac dullness was increased, bellows murmurs were The area of heardoverall the valves, pulsation at radical artery was soft and compressible. The spleen was enlarged and tender. the liver was normal insize and noglan dular swellings; the bones were not tender to-press ure, ( J) ul ; 347 DAYS PAST 18 TO COME Dr. George [losse Norton—Case V. Continued. A microscopic examination of the blood showed the following: Red bloodcells, 2,800,000 per cubic millimetre: hemoglobin, 35 per cent. The white cells were greatly increased and of irregular shape. The treatment wasasfollows: Patient was advised tolive on a mixed diet, with an abundanceof fresh air, and moderate outdoor exercise; she was ordered to take a tablespoonful of Pepto-Mangan, (Gude) three times daily after meals. At the end of four weeks’ treatment a blood examination showedthe redcells to have increasedto 4, 600.000 per cubic millimetre, and the hemoglobin to 75 per cent. The great improvement in this case of an increase of more than one million and one-half red bloodcells to the cubic millimetre and an increase of more than 100 per cent of hemoglobin is worthy of special notice. The patient’s condition progressively improved, all nervous symptoms subsided, appetite soon returned to normal. Complexion became rosy, and her disinclination for outdoor exercise suddenly disappeared; she took on newlife and energy.” © Or 0% KAN eae Ate eo j— pf { J / A % _ Cte 1f2 4 Z UY Or~4 fi y ST Fx ~ f 0 A DRA hin CMa gk 4 (\. 7 = Ore ene "i i Aarhd 0 j pee (Aun J oL¢ A LA fl JIA ‘ N VA, a RF Vv ae ~ t/ ~—t rus b ar f 4 A A y LY 2. ) ds A eo, f . 1 w rr, KR LLATIIKVOtay f ot we +t , (h/, W/m ot — 2, , Ld / x tit (3 Ny AK l J Cc fo, Dd_t4 Lees’ ae hp ur fro Y Pvy ‘ + te = ~f— 0) WALZ ene 9 AG (oy Aeon eh Sh Monday, December 14 348 DAYS PAST Tuesday, December 15 17 To CcomME 349 DAYS PAST SCROFULA ORSTRUIMOUSDIATHESIS is difficult to combat. It works in the dark like a foe in the night; it steals the life of the and hidden places be overcome bystrength and power in the blood. It can only blood supply. The lymphatics become chronically inflamed, and the on the blood for its regeneration and nourishmen bone, which calls same, degenerates, resulting in a caseation t, not receivingthe products. Scrofula being a tubercular diseasof the inflammatory e, heredity plays a major part. It ravages the organs of the body and system generally with its toxic infection. Pepto-Mangan (Gude) has been tested practice in cases of ‘‘scrofulus originale,” in hospital and private timable value by enriching the blood and and has proven of inespower, producing healthytissue in the renewing its reconstructive place of waste degenerature. j Wp w Wyr oh ate Leder Le » A On ctl; - ie L yypf 7124-72-271 Cnt e 79 ' Dr. E, Grun, Vegvar, Hungary, writes: ) ayHi ye Ant “Yrs >) A f } Foe iy i ene ou 4 / a? ) 4 £2 7 / fo ArT } . 5 ft Ay - oA OAL fi Br 4 J} 7 \ cd e A Ec oy iti1oe - Loot L 7 O39091% A ~~ 7) f 7 Lee Ae “I tried your Pepto-Mangan (Gude) in the case of a woman, 23 years old, who suffered from a severe attack of diphtheria, Behring antitoxin had to be injected on two occasions, and nine days elapsed before recovery ensued, and there was a pronounced conditio n anzemia with loss of appetite. I must confess that I hesitatedin of resorting to yourpreparation, since the patient could not even tolerate milk. In spite of this fact, the remedy was well borne; the appetite improved, and afterfive days she was able to partake of the more digestible meats, After she had taken twobottles of your prepara tion every trace of anemia had disappeared, Her cheeks became ruddy and the appetite excellent. This case demonstrates striking ly that we possess in Pepto-Mangan (Gude) an excellent remedy, which can be administered even in cases of impaired digestion, and I wouldplace it at the head of all ferruginous preparations.” 4 A L f 4 f p)‘ 7 fe y QO f cone art eo y~ HAK Wednesday, December 16 350 DAYS PAST 15 To COME August 24, 1901. Dr, W. H. Wakefield, editor Carolina [Medical. Journal, Charlotte, N. C., writes: ‘In the treatment of corneal ulcers in anzemic patients in addition to appropriate local measures, I put my patients on Pepto-Mangan (Gude) with very satisfactory results. I find myself velying more on Gude’s Pepto-Mangan eachyear.” i eer Dr. Geo, Ben Johnson, Richmond, Va., says: ‘“‘T have the highest opinion of Gude’s Pepto-Mangan and have used it very extensively, and always with good results.” Thursday, December 17 351 DAYS PAST 14 TO COME CAUTION that fraud and substitution may be better prevented Pepto-Mangan (Gude) is submitted in bottles of one size only, % xi., never being sold to dealers in bulk. Any druggist claiming to so purchase, or the re-filling of bottles is perpetrating a fraud on physician and patient alike. Gude’s Pepto-Mangan is the original and only presented to the protession after clinical observation in leading institutions by eminent men. Ay ! — (Ne 1 Friday, December 18 DAYS PAST 13 TO COME March 16, 1902. xr. Gottlieb Popper, Regimental Surgeon, Komotau, Bohemia writes; ‘Mypatients gladly take your Pepto-Mangan (Gude) and I can hig hly praise and recommend it to others, In two cases of convalescence after typhoid fever and extirpation of auterinemyoma,I obserrved verysatisfactory results.’ ? cle , P ) , A y, i Saturday, December 19 272 DOS DAYS PAST Eairict from Kditorial in 12 TO. COME ‘‘TheAlabama TMedical and Surgical Age:’”’ “The Tr, Chloride of Iron, which is the most generally usedofall preparations in the Pharmacopeeia, is very astringent; it can rarely be tolerated by a weak stomach; it discolors and injures the teeth, nd always constipates the bow els. ‘‘Gude’s Pepto-Manganisfree ofall these gbjectionable features.” d Fn ee ) Veit fe Sunday, December 20 354 DAYS PAST Monday, December 21 11 To COME 355 DAYS PAST 10 TO COME COMMERCIAL PRODUCTS December18, 1901. intended for substitution of the original should have no standing Dr. Adolph, Assistant to Royal University Eye Clinic, with the profession. There is no evidence submitted to prove their merits, simply a statement ‘‘just as good,” “‘just the San? etc. Gude’s Pepto-Mangan has the endorsement of eminent menin the medical profession and onlyafterscientific investigations. Clinical reports will be forwarded upon request. a : ° 5 _Konigsberg, I. P., Germany, writes: ‘I have prescribed your Pepto-Mangan (Gude) in several cases of scrofulous and anzmic children. The preparation is very willingly taken, and I have had the satisfaction of observing inall the cases an increase in weight, a healthy color of the face, and a gain in ; strength.” 4] Y , fo ) OAS _y / L d a ( Los A + {/ nN C i“ ; MN /y Fi eh m A. f* v y j 7 Ht CALS ” ( é Vy 2 - ij rt y 74 f 4 / 0-3 4 St pian uc Q y y f 4 Ok £ hry pets f ; 4) Pt wr? IOce tay etme) f as) an dan Let i op A ~— h, [7 Catt. Tuesday, December 22 356 DAYS PAST 9 To COME Dr. Elias Wildman, Haddon Heights, N. J., says: “I have used your Pepto-Mangan (Gude) and findit the most reli- ble preparation on the market. a —_, | J a Sig——<— It has been afaithful agent to me in cases of infancy and even old age where I require a good systemi c tonic, one which would beeasily absorbed by the stomach and bowels. Its uses in cholera infantum, marasmus will be noticed by hose using it. In debility, old age and patients recovering from exhausting fevers, your Pepto-Mangan (Gude) can bewrelied upon.” — SS piri a La GA FT /o ee ot OY ‘Lo Peau f ae —<j ge CALA be dy <AMmM_> = fs ae LA. ¢ C., ad d Yy : ie — j //~ 4 J - 7h A so /) 1 i fA f it ? Be. Sd Pore SPC oy c Wednesday, December 23 357 DAYS PAST 8 TO COME CAUTION. The prescribing of an original bottle Pepto-Mangan (Gude) % xi, will obviate all possibility of substitution, We know upon doctor’s prescriptions for quantities less than an original bottle, the doctor and patient have been defrauded alike. A substitute submitted to us for examination, after analysis, was found to be simply Ess. Pepsin and Tr. Chlor. Iron. N ational laws should make such nefarious practices criminal. When commercial bulk goods are sold to the dealer competition regulates price—price regulates quality, therefore irresponsible rties sell products in bulk relying on the label toeffect sales. Thursday, December 24 358 DAYS PAST Friday. December 25 359 DAYS PAST 7 TO COMER 6 TO COME August 10,1901._ May 25, 1902. Dr, Coester, Lippstadt, Germany, writes: W.C. Wile, M. D., editor New England [ledical Monthly, “I have learned to value your Pepto-Mangan (Gude) as a very serviceable iron preparation, which from my own experience I in- Danbury, Conn., writes: “Tt is quite a good many years since I began to prescribe Gude’s tend to give the preferencein the future.” ee IF L471 Pepto-Mangan. SSS I find it meets all indications where iron is re- quired in the patient. It is a certainty which the doctor cannot afford to dispense with in the treatment of all those diseases which require iron in any form. I have found it invaluable,” In debility resulting from typhoid and scarlet fevers, diphtheria, te., Pepto-Mangon (Gude) is indicated as a general reconstructive. 0 (eS ; CY sann b A Yr LOTMA AS peed y+CC On Ot ——t yy UV « Ces e de voh5 07s yt Li eo Din Li Su ie . 7. : o/ Gerdeond of fee Saturday, December 26 360 DAYS PAST Sunday, December 27 5 TO COME 361 DAY PAST Copyof Clause in Contract Existing Between Dr. A. Gude & Co., of Leipzic, Germany, and the M. J. Breitenbach Company, of NewYork City. “Sexo, 9.—And it is further agreed between Dr. A. Gude & Co., party of the first part, and the M. J. Breitenbach Company, party of the second part, that if at any time the said M. J. Breitenbach Company should, by device or byadvertising, attempt to increase their business in Gude’s Pepto-Mangan other than through the reeognized channels to the Medical Profession, then in such events this contract is to become null and void, andall right of the M. J. Breitenbach Company existing under this instrument immediately become the property of said Dr. A. Gude & Co. without recourse to law.” January 16, 1902. Dr. Brasch, Berlin, Germany, writes: “The experiments with your Pepto-Mangan (Gude) have been come pletely satisfactory. I order your preparation almost exclusively. L , my Sac Cow Came pee Ad ; f drwy Y° C Oba tk Pit Aras Chemo,t » ~ J J Cheek ved phe go Cp Y \Y \ Dak mesSna try, Vey Of hye ) =| Kol nae ae LQ 7 (LL Oth. Aisi ol 4 ] iL Mb ‘Cra tif £ t. ¥Y GQrf &_ Zl2_- EL C234 Cy od Lf nd eo Gao V4 57 (—U ! J A. A A j a4 4 1 ‘ l LL") 77 meee lint YQ é AL 4 7 [7 rofl . om L_A Seeing \ 7 os & 4 ( AL ee =) wl Z Sy Ae Le 7 C L 4 —___—_—_—_— ay gZ as , caer oe ¥ Ste co Ap 47 Oe jf tn z mn 4L at a rd J 2 , 4= t OL€ Lh w% 22, a » ‘ x LZ ( b L }- oP Alex \ An Lem te LL ithe bt a LtCz+4 Coa nets AL 2 feta afLealtLt. ‘OLe ot ofa 4 70 COME 4f vf . be Ae rr } 411 ot f; CsCl te, ex As (Jr e y x a: re LLAMAS . ” ny = Monday, December 28 362 DAYS PAST Tuesday, December 29 363 DAYS PAST 3 TO COME Dr. [1. C. Woodruff, St. Louis, Mo., in a Clinical Report, August 19, 1901. Albert E. Bulson, Jr., B. S., T1. D., editor Fort Wayne says: Medical Journal-Magazine, writes: _ ; ) id ‘Tn submitting this article to the profession, it is not my intention to enter into a scientific discussion as to the value of PeptoMangan (Gude) as a red bloodcell producer; that fact has been conclusively proven by men eminentin the profession, as, for instance, by Loomis, Summa, Von Ruck and many others. I will confine myself to the practical application of this valuable combination.” ‘‘T havefor several years used Gude’s Pepto-Mangan with much satisfaction in impoverished conditions of the blood, and particularly anemia. The preparation is not only very palatable, but seems to act very efficiently in the conditions for which it is indicated Mal A A? LAY G C7 3 eZ Oo FA LA oa CLeggar Lyle olal, UU: # ¥ it1 Ses UN-Rome Cpeay nr b who LEAP OVALS 4 /)\ { VY(Ld2h_o/ i ee ‘ys r CC) oe — Ve 2 ae yA 4) A At do bc IN aae hs f, Jr WA a. ULF 4 C Ori s t- Af ae Y 4 Oe?Of/ “S f oe/} v rel _ a ae ) n ty -— gy \ 2 bool AL . peta ae . ht A ta 2 TO COME bf‘ . aot. oy ae f i oe VA, OC4LAMVY+* 01K Ln Ale tes fre eee ba, he Sick ies Jus aype Ot AQAA Hmrat 0 ( ~ 1 Gp OAS Ugh at of oy Slons, Tagied., al fin MFWen tO A ane LAr e hina yu Lge je etaetee of 5 ‘)/ Ux. nen adn (Yr haeet c B11 net rarer +| ! rn Liem ble it Lp p Pow ee December 30 364 DAYS PAST ee December 31 365 DAYS PAST 1 To COME 0 TO COME May20, 1902. August 15, 1901 Dr. E. Gunther, Wohlsdorf, Germany, writes: Editor Gaillard’s [ledical Journal, New York, writes : “I prescribed your Pepto-Mangan (Gude) in a case of anemia and am much satisfied with the results, a very valuable feature being that the remedy was absolutely free from any disturbing effect ‘Were we to mention all of the cases in which we haveused upon the stomac*h.”? 7> ’s Pepto-Mangansuccessfully you would have nothing to Pe in your book ‘but what has been our experience, and for Pt Lis son we will avoid going into the matter in details, but beg to ss 4@EDJ ee, Contayu e ycee wehavenever in our expe rience foi a so valu:abe paration for the condition in which itis indicated frome Bt ot Taj, Co 31 ee lpn (D5 Fo7ae a et Deng one ud Lil le, 5 fe f- AK eo FOULsmngety “C Z >) t+1— C Ce-F a Yiceae 7 af 4 La 2 AD A—mn>._14_ 1». oF |Opeste Ge Cefe a fo h/ ONm oe + anea o/ [8 22, ae fai N. Y., Cras ‘Gy WE. LnGQ a OX - ory Af hPa - a Cash Receipts: JANUARY, 1903. | Charged: fe | Seer Cash Receipts: FEBRUARY,2 1903. || Charged: MARCH, 1903. > N : NWN -/: WNW x W % N WwW Cash Receipts: || Charged: E WeGaate Receipts: || Charged: Cash Receipts: recA a oh norm WO Fe 100. OO oe Sos CH ot tS Se Ss AUGUST, 191a(ID Cash Receipts: As Cc harge a: |( maAmMYT MHONnADAaASoXA eS ow SEPTEMBER, 1903. | Cash Receipts: ‘|| -Chargea: OCTOBER, 1903. : ‘Cat 1 Receipts: || Charged: NOVEMBER, 1903. DECE Cash Receipts: =e A Mere HOH AD AD MEMORANDUM. MEMORANDUM. MEMORANDUM. | MEMORANDUM. MEMORANDUM. What we claim for GuprE’s PrptoManacan, and the same has never Rote. been refuted, is that the metals, Iron and Manganese, exist in an organoplastic form, the solution being positively neutral in reaction. The metals are held in perfect solu- tion as TRUE PEPToNATES, being producedbya process heretofore unknown. This preparation, Gupz’s Prptro-Manaan, when taken into the stomach under- goes no chemical change whatsoever. Being practically pre-digested, it is readily absorbed by the mucous membrane of the stomach, the process of assimilation is easy, and the metals are taken up by the blood immediately. Commercial solutions of Iron and Manganese are made with the aid of Acids or Alkalies, and notably the latter; that is, they are held in solution in the presence of a comparativelylarge quantity of Caustic Soda, which neutralizes, to a certain extent, the Hydrochloric Acid in the stomach, and liberates Oxides of Iron and Man- ganese. The latter, through the action of the Hydrochloric Acid of the gastric juice, are converted into chlorides of these metals, and thus cause a caustic action upon the gastric mucous membrane. This has been proven byProf. Bunge, as shown in his very able article read before the Congress of Medicine, at Munich, 1895. M. J. BREITENBACH COMPANY, 53 WARREN STREET, NewYork, Specify ORIGINAT, -SIMII I BOTTLE OF Prescribe an GUDE’S NEVER SOLD IN To be procured from Druggists generally. Original and avoid substitution. BULK. tit CO | eat | 00] ire 1400 100 IE ~~ aAe | aN 13 14 15 16 17 18 19202122 2324 21 22 23 24 95 96 2' 2 293031 1 2 21 22 23 24 25 26 27 28 2930 1 2 3 4 | Scptember. Beware of preparations with similar sounding names or preparations There is only one PEPTO-MANGAN and that is **GUDE’S.’’claiming to be the same, Substitution compels our calling your attention to this fact. GUDE’S PEPTO-MANGAN indicated in all cases of conval escence. WILL MAKE BLOOD, FLESH, AND GIVE STRENGTH. The duration of human pregnancyis about 275 days. This is subject some variatio n, and the longestperiodis still undetermined. As labor occurs in the larger proportion of cases betweento 270 and 29( ) days fromthe last menstruation, it al to reckon either from thefirst orlast dayof this period, taking as the mean 280 days, or a little over nine calendar For this approximate calculation thefirst dayof the menstrual period may be used as being morereadily ascerThe table presents at a glance the beginning and end of 280 days for every day of the year. Find the date of menstruation in the upper line of the horizontal row, and the 280 days. In leap year, if the period of pregnancy includes figure below, with the corresponding month, will indicate February, the time for labor will be one day earlier than that given in the table, sees 45 & 215 15 16 17 18 19 20 21 22 23 94 95 96 97 28 29 112.3 4 5 6 8 910 11 12 13 14 15 16 17 18 19 20 21 22 24 95 96 27 28 29 20 16 17 18 19 20 21 22 23 24 25 96 97 § 3031123456 8 910 11 12 13 14 15 16 1718 19 202122 23 2425 25 97 28 29 910 11 12 13 14 15 1617 1819 20 2122 23 24 25 26 27 28 29 80 5. 8 9101112 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 982930 193845 6 7 | October. July.. November..../|19 3 August ¢ December. ...| St est et rt 1 27 ws 29 30 3 18 19 20 0 21 2223 9495 262798293250 26 311/23 4 & 5 16 17 18 19 20 21 22 24 95 26 27 28 29 30 . 18 1920 21 222324952627 23 28 293031 12°34‘|| February. 213 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31|| 317 18 19 20 2122 23 24 95 26 2728123 45 6 7 213 14 15 16 17 18 19 2021 22 23 24 95 26 27 28 29 30 2021 22 23 242526 272829 3031 12°34 5 6 213 14 15 16 17 18 19 20 21 22 93 24 25 25 27 28 29 30: 8 19 20 22 23 24 25 26 2728 293012 8 4 5 6 14 16 17 18 19 20 21 22 23 24 25 £6 27 28 29 30 21 23 24 252627 282930 31 1°28 3 4 5 14 16 17 18 19 20 21 22 23 24 25 26 21 23 24 25 26 27 98.29 301 2 8 et Se October.......|| 9 10 BUND scsacaas es] | 111 4 56 67 8 910 March...... 18 9101112 13 14 15 16 17 3 PUT ccadeesncechl A : 5 ADT ices cecsere | 7 _8 August........| 1 a4 5 8 910 11 1213 14 15 45 6 7 8 9101 101 8 910 11 12 13 14 151 456% 8 9101 910 11 12 13 14 151 —Oo 2 13 frauded alike. : de- May......-..--. | 8 91011 12 1: been September....|| 1 JUNC... s al bottle the Doctor and stn ‘| have origin- BOT eseunsec | February ..... | tities less th anan Ja prescriptions for quan- 8 S 834567 We know upon Doctor aa> 16 17 18 19 20 23:24 25 26 27 6 17 18 19 20 23 24 25 26 27 original bottle DET csvenes substitution. 213 14 5 2021 22 13 14 5 20 21 2 (3 xi) will obviate all pos- January......| 23 45678 10 October......... 891011 12 13 14 15 16 1 17 2345 67 8 910 910 11 12 13141516 17 PEPTO-MANCAN March...... ; patient of By W.W.Ety, M.D., ROCHESTER, N.Y. The prescribing of an De sibility O BSE TR TCA ei AsB le. CAUTION. REEALey Nas \v S Cneee Le ioe ARE ITER GACMEAG Of WERE eC T, Re ee