Identifier |
20210220_nanos_posters_039 |
Title |
Downbeat Nystagmus In Patient With AQP4-Positive Neuromyelitis Optica |
Creator |
Blaire Cote; Isabella Canut; Charles Maitland |
Affiliation |
(BC) (IC) (CM) Florida State University College of Medicine, Tallahassee, Florida |
Subject |
Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid); Nystagmus; Optic Neuritis; Demylinating Disease |
Description |
Neuromyelitis optica (NMO) is characterized as a rare autoimmune inflammatory disease typically presenting with loss of vision and paralysis. NMO differentiates from other autoimmune diseases with antibodies selective for aquaporin-4 (AQP4), a water channel located within the optic nerves and spinal cord. It is hypothesized that AQP4-IgG can more readily enter the perivascular space rather than breaching the blood-brain barrier encountering AQP4 on the surface of choroid epithelial cells. Downbeat nystagmus (DBN) is associated with structural, metabolic, and autoimmune causes like multiple sclerosis. Clearly documented DBN is rarely reported in NMO. |
Date |
2021-02 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2021 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2021: Poster Session I: Neuro-Ophthalmic Disorders of Neurologic and Systemic Diseases |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2021. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6bp5xxp |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
1671526 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6bp5xxp |