Updates in the Management of Cryptogenic Stroke and Patent Foramen Ovale

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Title Updates in the Management of Cryptogenic Stroke and Patent Foramen Ovale
Creator David K. Stone, Natalie Buchwald, Christina A. Wilson
Affiliation First Physicians Group of Sarasota Memorial Health Care System (DKS), Sarasota, Florida; and Department of Neurology (NB, CAW), University of Florida, Gainesville, Florida
Abstract Background: Stroke is a common neurological disorder and may present with visual symptoms. A thorough workup is warranted to determine the underlying cause of stroke to optimize secondary prevention. Despite a full workup, a high-risk mechanism may not be identified. Optimal treatment in this patient population has been the subject of recent research, particularly with regard to low-risk stroke mechanisms such as patent foramen ovale (PFO). Evidence acquisition: Using PubMed and published stroke guidelines, an evidence-based literature review was performed. Results: In this review, we compare cryptogenic stroke with the newer concept of embolic stroke of undetermined source, summarize the most common causes presumed to underlie these strokes, and review the evidence for optimal antithrombotic management. We also review recent clinical trials demonstrating a benefit for percutaneous closure of PFO for secondary stroke prevention in select patients. Conclusions: Stroke management is based on evaluation of individual patient-risk factors. Evaluation and treatment is ideally directed by a vascular neurologist to ensure optimal secondary prevention, especially in cases where an underlying etiology is not identified on initial workup.
OCR Text Show
Publisher Lippincott, Williams & Wilkins
Date 2020-03
Type Text
Source Journal of Neuro-Ophthalmology, March 2020, Volume 40, Issue 1
Language eng
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
ARK ark:/87278/s6wb10k1
Setname ehsl_novel_jno
Date Created 2020-09-14
Date Modified 2021-05-06
ID 1592865
Reference URL https://collections.lib.utah.edu/ark:/87278/s6wb10k1
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