| Identifier |
EEC-LHON-Pseudoedema |
| Title |
Optic Disc Pseudoedema Due to Leber Hereditary Optic Neuropathy |
| Creator |
Rahul A. Sharma, MD, MPH; Valérie Biousse, MD |
| Affiliation |
(RAS) Neuro-ophthalmology Fellow, Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia; (VB) Cyrus H. Stoner Professor of Ophthalmology, Professor of Ophthalmology and Neurology, Departments of Ophthalmology and Neurology, Emory University School of Medicine, Atlanta, Georgia |
| Subject |
Leber Hereditary Optic Neuropathy; Optic Disc Pseudoedema; Fluorescein Angiography |
| Description |
A 23-year-old woman developed sequential painless central vision loss in both eyes (right eye 5 months ago and left eye 2 months ago). Her examination showed bilateral optic neuropathies: visual acuity: 20/300 eccentrically OU (no improvement with pinhole); pupils: equal and reactive with no relative afferent pupillary defect; color vision: control plate only OD, 3/14 plates correct OU; visual fields: large cecocentral scotomas OU. Goldmann visual fields (GVF) showed bilateral cecocentral scotomas. Intravenous fluorescein angiography (IVFA) of both eyes showed no leakage from either optic disc on the late phases, indicating that the patient's disc elevation was consistent with optic disc pseudoedema rather than true disc edema. MRI brain and orbits with contrast was normal without optic nerve enhancement. NMO and MOG antibodies were negative. Genetic testing for LHON showed the m.3460 point mutation, confirming the diagnosis of LHON. |
| Date |
2020 |
| Language |
eng |
| Format |
application/pdf |
| Format Creation |
Microsoft PowerPoint |
| Type |
Text |
| Collection |
Neuro-Ophthalmology Virtual Education Library - The Emory Eye Center Neuro-Ophthalmology Collection: https://novel.utah.edu/eec/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890 |
| Rights Management |
Copyright 2002. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6qk32xz |
| Setname |
ehsl_novel_eec |
| ID |
1579299 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6qk32xz |
