Clinical, Laboratory, and Histopathological Findings in Patients with Suspected Temporal Arteritis

Temporal arteritis, also known as giant cell arteritis (GCA), is an idiopathic systemic inflammatory syndrome that typically affects patients over the age of 60 and can cause catastrophic irreversible vision loss from ocular ischemia. Temporal artery biopsies (TABs) frequently show changes that can be diagnostically challenging, in particular healed or treated GCA and those with less robust CD68 staining. We aim to identify predictive variables for the clinical diagnosis of GCA using clinical examination findings, laboratory tests, and histopathologic features.