Jacobson Lecture - Optic Neuritis: Past, Present, and Future (Slides)

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Identifier 20200311_nanos_jacobson1_01-slides
Title Jacobson Lecture - Optic Neuritis: Past, Present, and Future (Slides)
Creator Steven Galetta, MD
Subject Multiple Sclerosis; Optic Neuritis; Optical Coherence Tomography; Low Contrast Letter Acuity; Magnetic Resonance Imaging
Description OCT has provided a basis for correlating structural aspects of anterior visual pathway axonal and neuronal loss with visual function in ON as well as in MS. It is now known that patients with MS have thinning of the retinal nerve fiber layer (RNFL, axons) and ganglion cell/inner plexiform layer (GCL+IPL, neurons) even in the absence of a history of acute ON. Such patients have clinically meaningful worsening of vision and quality of life (QOL). We now also recognize that is an inter-eye RNFL and GCL difference that may predict an underlying optic nerve lesion. Newer techniques such as retinal nerve fiber layer textual analysis may provide additional sensitivity in defining more subtle forms of optic nerve injury. Our ability to separate out the anterior and posterior visual pathway contributions to RNFL loss by hemi-segmentation techniques will be important to understand the location of the disease burden in MS. When coupled with new MRI sequences such double inversion recovery images, symptomatic and asymptomatic optic nerve lesions will become easier to verify. Going forward, OCT is a powerful tool that may be used to assess neuro-repair and neuroprotective mechanisms in both acute and chronic optic nerve injury.
Relation is Part of NANOS Annual Meeting 2020: Jacobson Lecture
Contributor Primary Steven Galetta, MD
Publisher North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Date 2020-03
Format application/pdf
Source NANOS Annual Meeting 2020
Rights Management Copyright 2020. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6vm9n6f
Setname ehsl_novel_nam
Date Created 2020-04-16
Date Modified 2020-05-26
ID 1541469
Reference URL https://collections.lib.utah.edu/ark:/87278/s6vm9n6f
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