Identifier |
20200308_nanos_posters_082 |
Title |
Seven Plus Seven Equals Four |
Creator |
Editha Johnson; Marc Dinkin; Cristiano Oliveira |
Affiliation |
National Eye Institute, Bethesda, Maryland |
Subject |
Orbit; Ocular Motility |
Description |
T helper type 2 cells (Th2) has strong correlation with IgG4 disease severity, where its production of the cytokine interleukin 4 (IL-4) is instrumental in the pathogenesis of IgG4-related disease. Dupilumab, a monoclonal antibody and antagonist of IL-4 and IL-13 receptors, is approved for treatment of chronic rhinosinusitis and should theoretically prevent development of IgG4-related disease. Our patient is a 59 year old male with eosinophilic asthma and chronic rhinosinusitis who developed severe progressive orbital inflammatory disease, initially presenting as eosinophilic granulomatosis with polyangiitis but ultimately diagnosed as IgG4 disease despite dupilumab. |
Date |
2020-03 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2020 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2020: Poster Session I: Clinical Highlights |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2020. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6cc68f4 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
1539310 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6cc68f4 |