Identifier |
20190319_nanos_sciplatform3_06_slides |
Title |
The Stressed Optic Nerve at High Altitude and Treatment with Chemical Chaperon |
Creator |
Yaping (Joyce) Liao; Alexandra Camargo; Matthew Dardet; Varun Kumar; Mohammad Shariati; Roopa Dalal; Vinicio de Jesus Perez; Louise Mesentier-Louro |
Affiliation |
(YJL) (AC) (MD) (VK) (MS) (RD) (VdP) (LM) Stanford University, Stanford, California |
Subject |
Optic Neuropathy |
Description |
High altitude-associated non-arteritic anterior ischemic optic neuropathy (NAION) [1-3] typically occurs in younger patients who have disc-at-risk and few other risk factors [4-9], raising the possibility that hypobaric hypoxia may be the tipping point of vision loss. In this study, we investigated the effects of systemic hypoxia on the retina and optic nerve and assessed the therapeutic potential of pre-treatment with chemical chaperon 4-phenylbutyric acid (4- PBA), which reduces endoplasmic reticulum (ER) stress. |
Date |
2019-03 |
Language |
eng |
Format |
application/pdf |
Format Creation |
Microsoft PowerPoint |
Type |
Text |
Source |
2019 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2019: Scientific Platform III |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s67q3k77 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
1455038 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s67q3k77 |