Rituximab May Confer Protective Effect on Retinal Nerve Fiber Layer in Multiple Sclerosis

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Identifier 20190319_nanos_posters_213
Title Rituximab May Confer Protective Effect on Retinal Nerve Fiber Layer in Multiple Sclerosis
Creator Deepak Soneji; Shreya Nayak; Islam Zaydan; Gabrielle Bonhomme; Ellen Mitchell
Affiliation (DS) (SN) (IZ) (GB) (EM) University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Subject Demeylinating Disease; Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Eyelid & Adnexal Disease; Neuro-Ophth & Systyemic Disease (eg. MS, MG, Thyroid)
Description Painful visual loss due to optic neuritis is a common presentation for an acute flare of multiple sclerosis (MS). Optical coherence tomography (OCT) has emerged as a tool to evaluate thinning of the retinal nerve fiber layer (RNFL) in patients with demyelinating conditions and may be useful in assessing subclinical progression of disease. Disease modifying therapies such as natalizumab have been implicated in stabilizing RNFL loss in MS (Talmage et al. 2017), but no such study has been done with Rituximab, which is a monoclonal Anti-CD20 antibody shown to be effective in treating MS (Alcala et al., 2018).
Date 2019-03
Language eng
Format application/pdf
Type Text
Source 2019 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NAM 2019: Poster Session II: Scientific Advancements in Neuro-Ophthalmology
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6wd8j8z
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Setname ehsl_novel_nam
ID 1432871
Reference URL https://collections.lib.utah.edu/ark:/87278/s6wd8j8z
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