Optical Coherence Tomography Findings in Papilledema Versus Optic Disc Drusen

The role of optical coherence tomography (OCT) to differentiate between papilledema (PE) and optic disc drusen (ODD) has been largely studied, however, it is still not clear whether this type of imaging is able to distinguish between the 2 entities. Indeed, whether peripapillary retinal nerve fiber layer (RNFL) as measured by OCT is thicker in eyes with PE than in eyes with ODD is still an open question. Furthermore, in recent reports, eyes with PE displayed peripapillary hyperreflective mass lesions, simulating buried ODD.