Episcleral Delivery System for Neuroprotection in Optic Neuropathy

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Identifier 20180306_nanos_posters_285
Title Episcleral Delivery System for Neuroprotection in Optic Neuropathy
Creator Kimberly Cockerham, Katie Topping, Andrea Kossler, Jeffrey Goldberg
Subject Optic neuropathy, Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc) Eyelid & adnexal disease, Optic nerve trauma and treatment, Neuro-ophth & systyemic disease ( eg. MS, MG, thyroid)
Description For many optic nerve disorders, there are limited therapeutic options to preserve vision. Under successive DOD Awards, a sustained choroid/retinal Episcleral Delivery System (EDS) has been developed to deliver drugs for weeks to years. The IND enabling work to date includes Episcleral Brimonidine for acute neuroprotection, EC-4565 (stabilizes mitochondria/catalytic anti-oxidant/oxygen free radical scavenger) for sustained neuroprotection and dexamethasone to mitigate inflammation. The EDS can deliver any small molecule that is currently used as an eye drop and most intravitreal injections and intravenous infusions.
Date 2018-03
Language eng
Format application/pdf
Relation is Part of NANOS 2018: Poster Presentations
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
ARK ark:/87278/s61c5x6c
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Contributor Primary Kimberly Cockerham
Contributor Secondary Katie Topping, Andrea Kossler, Jeffrey Goldberg
Setname ehsl_novel_nam
ID 1310616
Reference URL https://collections.lib.utah.edu/ark:/87278/s61c5x6c
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