Identifier |
20180306_nanos_posters_285 |
Title |
Episcleral Delivery System for Neuroprotection in Optic Neuropathy |
Creator |
Kimberly Cockerham; Katie Topping; Andrea Kossler; Jeffrey Goldberg |
Affiliation |
(KC) (KT) (AK) (JG) Stanford, Department of Opthalmology, Stockton, California |
Subject |
Optic Neuropathy; Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Eyelid & Adnexal Disease; Optic Nerve Trauma and Treatment; Neuro-ophth & Systyemic Disease ( eg. MS, MG, Thyroid) |
Description |
For many optic nerve Disorders; there are limited therapeutic options to preserve vision. Under successive DOD Awards, a sustained choroid/retinal Episcleral Delivery System (EDS) has been developed to deliver drugs for weeks to years. The IND enabling work to date includes Episcleral Brimonidine for acute neuroprotection, EC-4565 (stabilizes mitochondria/catalytic anti-oxidant/oxygen free radical scavenger) for sustained neuroprotection and dexamethasone to mitigate inflammation. The EDS can deliver any small molecule that is currently used as an eye drop and most intravitreal injections and intravenous infusions. |
Date |
2018-03 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2018 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2018: Poster Presentations |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
ARK |
ark:/87278/s61c5x6c |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
1310616 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s61c5x6c |