Optic neuritis occurs during multiple sclerosis (MS) and induces retinal ganglion cell (RGC) loss. Thus, neuroprotective therapies are needed. We previously showed that intranasally delivered ST266, the biological secretome of Amnion-derived Multipotent Progenitor cells, attenuated loss of vision and RGCs in experimental optic neuritis, but mechanisms of its actions are not known. Potential mechanisms were examined in the experimental autoimmune encephalomyelitis (EAE) model of MS.
Relation is Part of
NANOS Annual Meeting 2017: Scientific Platform I
Reas Khan, Kimberly Dine, Larry Brown
Spencer S. Eccles Health Sciences Library, University of Utah
2017 North American Neuro-Ophthalmology Society Annual Meeting