Title |
Dyschromatopsia in Multiple Sclerosis Patients: A Marker of Subclinical Involvement? |
Creator |
Helena Felgueiras, MD; Joana Parra, MD; Simão Cruz, MD; Pedro Pereira, MD; Ana F. Santos, MD; Adriana Rua, MD; Dália Meira, MD; Pedro Fonseca, MD; Catarina Pedrosa, MD; João N. Cardoso, MD; Cristina Almeida, MD; Maria Araújo, MD, Ernestina Santos, MD |
Affiliation |
Neurology Department (HF), Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal; Neurology Department (JP), Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; Neurology Department (SC), Hospital Fernando Fonseca, Lisboa, Portugal; Neurology Department (PP), Hospital Garcia de Orta, Almada, Portugal; Neurology Department (AFS), Hospital de Braga, Braga, Portugal; Neurology Department (AR), Centro Hospitalar do Porto, Porto, Portugal; Ophthalmology Department (DM), Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal; Ophthalmology Department (PF), Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; Ophthalmology Department (CP), Hospital Fernando Fonseca, Lisboa, Portugal; Ophthalmology Department (JNC), Hospital Garcia de Orta, Almada, Portugal; Ophthalmology Department (CA), Hospital de Braga, Braga, Portugal; Ophthalmology Department (MA), Centro Hospitalar do Porto, Porto, Portugal; Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto (ES), Porto, Portugal |
Abstract |
To investigate corneal biomechanical properties among individuals with unilateral nonarteritic anterior ischemic optic neuropathy (NAION) compared to healthy gender- and age-matched subjects.; ; The study subjects were separated into 2 groups: 66 eyes of 33 patients with unilateral NAION (study group) and 33 eyes of 33 healthy individuals (control group). Reichert ocular response analyzer (Reichert Ophthalmic Instruments) was used to assess corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc), and Goldmann-correlated intraocular pressure values. Also, central corneal thickness was measured using Scheimpflug camera combined with a Placido disc corneal topographer (Sirius; Costruzioni Strumenti Oftalmici).; ; Mean CH and median CRF values were significantly lower in the affected eyes (8.8 ± 1.8 mm Hg, 9.4 mm Hg, respectively) and contralateral unaffected eyes (9.1 ± 1.6 mm Hg, 9.8 mm Hg, respectively) of NAION patients than those in the control group (9.9 ± 1.3 mm Hg, 10.4 mm Hg, respectively; all P < 0.017). Mean IOPcc was significantly higher in the affected eyes of NAION patients (19.2 ± 3.5 mm Hg) than in the eyes of control group (17.1 ± 3.6 mm Hg; P = 0.002).; ; CH and CRF are significantly reduced in patients with NAION, possibly indirectly reflecting structural weakness in the lamina cribrosa. |
Subject |
Older people; Biopsy; Giant Cell Arteritis; Humans; Male; Retinal Artery Occlusion; Retinal Vein Occlusion; Temporal Arteries; Visual Field Tests |
Date |
2016-09 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Publication Type |
Journal Article |
Source |
Journal of Neuro-Ophthalmology, September 2016, Volume 36, Issue 3 |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
ARK |
ark:/87278/s6x102hs |
Setname |
ehsl_novel_jno |
ID |
1276523 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6x102hs |