| Title |
Safety and Tolerability of Acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial |
| Creator |
Martin W. ten Hove, MD; Deborah I. Friedman, MD; Anil D. Patel, MD; Isabella Irrcher, PhD; Michael Wall, MD; Michael P. McDermott, PhD; for the NORDIC Idiopathic Intracranial Hypertension Study Group |
| Affiliation |
Department of Ophthalmology (MWtH, II), Queen's University and Hotel Dieu Hospital, Kingston, Ontario, Canada; Departments of Neurology and Neurotherapeutics and Ophthalmology (DIF), University of Texas Southwestern Medical Center, Dallas, Texas; Department of Ophthalmology (ADP), Dean McGee Eye Institute, University of Oklahoma, Oklahoma City, Oklahoma; Department of Neurology (MW), University of Iowa, Iowa City, Iowa; and Department of Biostatistics and Computational Biology (MPM), University of Rochester, Rochester, New York; NORDIC Idiopathic Intracranial Hypertension Study Group |
| Abstract |
The impact of prior neuro-ophthalmic syndromes on the performance on vision-based neuropsychological tasks in patients with multiple sclerosis (MS) is unknown. Two groups of MS participants, one with (Msos+) and the other without (Msos-), a history of neuro-ophthalmic syndromes, underwent neuropsychological assessment and were compared with healthy age- and education-matched controls (HC). Participants with Msos+ performed significantly worse on the symbol digit modalities test than the Msos- (P < 0.03) and the HC groups (P < 0.01) and coding (P < 0.01). A clinical history of neuro-ophthalmic syndromes is associated with reduced performance on visual processing speed tasks. |
| Subject |
Acetazolamide; Adolescent; Adult; Carbonic Anhydrase Inhibitors; Combined Modality Therapy; Diet, Sodium-Restricted; Double-Blind Method; Female; Humans; Intracranial Pressure; Male; Maximum Tolerated Dose; Middle Older people; Papilledema; Pseudotumor Cerebri; Quality of Life; Vision Disorders; Visual Fields |
| Date |
2016-03 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| ARK |
ark:/87278/s6qr8rmt |
| Setname |
ehsl_novel_jno |
| ID |
1276447 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6qr8rmt |
