| Identifier |
20170403_nanos_sciplatform1_05-abstract |
| Title |
Role of SIRT1 Activity and pAKT Signaling in ST266-Mediated RGC Neuroprotection (abstract) |
| Creator |
Kenneth Shindler; Reas Khan; Kimberly Dine; Larry Brown |
| Affiliation |
(KS) (RK) (KD) University of Pennsylvania, Philadelphia, Pennsylvania; (LB) Noveome Biotherapeutics, Inc., Pittsburgh, Pennsylvania |
| Subject |
Optic Neuropathy; Demeylinating Disease; Neuro-Ophth & Systyemic Disease (eg. MS, MG, Thyroid) |
| Description |
Optic neuritis occurs during multiple sclerosis (MS) and induces retinal ganglion cell (RGC) loss. Thus, neuroprotective therapies are needed. We previously showed that intranasally delivered ST266, the biological secretome of Amnion-derived Multipotent Progenitor cells, attenuated loss of vision and RGCs in experimental optic neuritis, but mechanisms of its actions are not known. Potential mechanisms were examined in the experimental autoimmune encephalomyelitis (EAE) model of MS. |
| Date |
2017 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2017 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2017: Scientific Platform I |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6qz652x |
| Setname |
ehsl_novel_nam |
| ID |
1273006 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6qz652x |
