Preliminary Baseline Characteristics of Patients with LHON Enrolled in RESCUE and REVERSE Gene Therapy Trials

Update Item Information
Identifier 20170404_nanos_posters_189
Title Preliminary Baseline Characteristics of Patients with LHON Enrolled in RESCUE and REVERSE Gene Therapy Trials
Creator Patrick Yu-Wai-Man; Nancy Newman; Robert Sergott; Molly Scannell Bryan; Valerio Carelli; Thomas Klopstock; Mark Moster; Alfredo Sadun; Jose-Alain Sahel; Catherine Vignal; Scott Uretsky
Affiliation (PYWM) Wellcome Trust Centre Newcastle Eye Centre Moorfields Eye Hospital UCL, Newcastle upon Tyne, United Kingdom; (NN) Dept. of Ophthalmology, Neurology and Neurological Surgery Emory University, Atlanta, GA; (RS) Neuro-Ophthalmology Service, Wills Eye Hospital, and Optic Nerve Research Center, Philadelphia, PA; (MSB) Optic Nerve Research Center and University of Illinois at Chicago, Chicago, IL; (VC) IRCCS Institute of Neurological Sciences; Unit of Neurology, University of Bologna, Bologna, Italy; (TK) Dept. of Neurology, Friedrich-Baur-Institute, Munich, Germany; (MM) Neuro-Ophthalmology, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA; (AS) Doheny Eye Institute and Department of Ophthalmology, UCLA, Los Angeles, Los Angeles, CA; (JAS) Sorbonne Universitホs IDV CHNO Fondation Rothschild Dept of Ophtho Univ of Pittsburgh, Paris, France; (CV) CHNO des Quinze-Vingts and Fondation Rothschild, Paris, France; (SU) GenSight Biologics, Paris, France
Subject Genetic Disease; Optic Neuropathy
Description RESCUE (NCT02652767) and REVERSE (NCT02652780) are Phase III, randomized, double-masked, sham-controlled trials of rAAV2/2-ND4, an intravitreally-injected gene therapy vector for the treatment of ND4 LHON. ; RESCUE patients have vision loss for ≤6 months and REVERSE patients from >6 months to 1-year.
Date 2017
Language eng
Format application/pdf
Type Text
Source 2017 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2017: Poster Presentations
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6kt0km5
Setname ehsl_novel_nam
ID 1272891
Reference URL https://collections.lib.utah.edu/ark:/87278/s6kt0km5
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