| Title |
Good Visual Outcomes After Pituitary Tumor Surgery Are Associated With Increased Visual Cortex Functional Connectivity |
| Creator |
Stefan T. Lang, MD; Won Hyung A. Ryu, MD, MSc, MTM; Yves P. Starreveld, MD, PhD; Fiona E. Costello, MD; the PITNET Study Group |
| Affiliation |
Division of Neurosurgery (STL, WHAR, YPS), Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Canada; Division of Ophthalmology (FEC), Department of Surgery, Cumming School of Medicine, University of Calgary, Cal- gary, Canada; Division of Neurology (FEC), Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Canada; Department of Neurological Surgery (WHAR), Rush University, Chicago, IL; and Hotchkiss Brain Institute (STL, FEC), University of Calgary, Calgary, Canada |
| Abstract |
Patients presenting with visual impairment secondary to pituitary macroadenomas often experience variable recovery after surgery. Several factors may impact visual outcomes including the extent of neuroaxonal dam- age in the afferent visual pathway and cortical plasticity. Optical coherence tomography (OCT) measures of retinal structure and resting-state functional MRI (rsfMRI) can be used to evaluate the impact of neuroaxonal injury and cor- tical adaptive processes, respectively. The purpose of this study was to determine whether rsfMRI patterns of func- tional connectivity (FC) distinguish patients with good vs poor visual outcomes after surgical decompression of pituitary adenomas. |
| Subject |
Vision Loss; Pituitary Macroadenomas; Surgical Decompression |
| Date |
2021-12 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Publication Type |
Journal Article |
| Source |
Journal of Neuro-Ophthalmology, December 2021, Volume 41, Issue 4 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| ARK |
ark:/87278/s6efgtpa |
| Setname |
ehsl_novel_jno |
| ID |
2116235 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6efgtpa |
