Ewart A. Swinyard, Salt Lake City, Utah : an interview by Robert Miller

Transcript (129 pages) of interview by Robert Miller with Ewart A. Swinyard on December 14, 1998-March 23, 1990. This interview is no. 380 in the Everett L. Cooley Oral History Project, and tape nos. U-1335 through U-1338

During 10 interviews, Swinyard (b. 1910), former Dean of the College of Pharmacy, University of Utah, recalls growing up in Logan, Utah, his education, his family, pharmacology research, and his tenure at the University of Utah. Interviewer: Robert Miller

AR EWART A. RA AN TN NGNS G SWINYARD A AR AR R NSRARO RN AN N i UNIVERSITY LIBRARIES OF MARRIOTT LIBRARY SALT LAKE CITY, UTAH 84112 UTAH EVERETT L. COOLEY ORAL HISTORY COLLECTION Date ?' =73 F‘J ‘h‘ Open and Usable usable with the after my following review. restrictions: Interviewee %&%MCW Interv ewe EWART Salt A. SWINYARD Lake An City, interview Robert Everett L. Cooley Tapes Nos. 14, Oral 1989 University Lake History U-1335 Marriott Salt by Miller Interviews December Utah Nos. to to 1338 1-10 March 23, Library of City, Project Utah Utah 1990 TABLE OF CONTENTS December 14, 1989 Tape #1: RN S T e I e B PT S 1) N e R D0 I B S A S A s o o it eo il SR SingbrugCompany Logan, WAl G D (70 [ e R e e e s e w0 wr e L L e e e sse s e s esio 5 0 o o e s 6s e L L e 5 e foionorsi o o Lo U o1 5 o a5 S R S ool P AL LSO SIS L L e B o o1 & ol ia ey el s oo o Sl (oo o v e e ot o A TEELTE L DTEE 0 D A R s 5 e o s e eT TR o e o i e NaunplREag SehI B B LT IR o e o 6 6 e e s el s 2 s s e es 4 o a0 e e i o 6 S U E 8 TR 9 e &L 860 8] o o e se s e w e e 5 e e 1 s el s 9 s 1 s R i i e e o 10 e e e e e e 10 © . . .. ... cc.vovncmeecosssosonnnss s 11 P 12 December 27, 1989 Tape #2: R RN IR R A T A AR A LU TR SECOR SRR LR S e ot b o6 S s en e e e e e s e se e e 13 e ale! 561 o) s 5 = & sio s siw 4e m e e e oo fhe oiciio i ors o oo me e e 14 o a = o sieis s s s o5 o 15 T R T T ST R o ee e s e 16 e e A 18 January 11, 1990 Tape #3: O Y N R P e e el e e el i i s 03] 5 3 a s o 6 0% wi o s s o Dates Ruth ParkinSon T meetSIErace ParkinSON . « -« s « & .o o« o o 5 s s s s 50 o e e SO S 0 e B EaslncNnvessityCallepe@f Pharmacy = DM s e ae s sie .. . .« <. cv v it I L L e e w e e e e e i i e s o nise 22 e e ee e e e i e e e e s 22 e e s 23 e e w e s 24 e 25 January 18, 1990 Tape #4: PR P s N B )e B R R L R L il S L oot ot sy o 5o o] o i i 83 e Mo ie, o 50 ia 10050 shies o o o oo 8 g o i, mive S e e e 27 . . c oo o os o ol s 58 s s oo o s s s s oo SR I - L e Founding of University of Utah College of Pharmacy CUTTIETT TEUUTED acviya o ofers s 27 e es s b w m e e s s w e 28 s s e 29 ...................... Lcfs dn ooceie oo e L O P SR 31 32 January 26, 1990 Tape #5: I o eT B e DS I e Spe D IEESE RpARYE SOl R . . el T D e e s s e . et e o s u s oo m s eins s o b s o 32 s 36 s e s sa e s e e e v s e e e e e s e s we 38 February 1, 1990 Tape #6: e PP fn sl (n v 4la s ia e s sl o University of Utah Medical School reorganization IR I I S S R e o o m mwa o e s o 40 R ..o . ............ Organization of University of Utah College of Pharmacy 39 44 . .................... 46 February 15, 1990 Tape #7: Travelstomeetimportantpharmacologists..............................48 . Ll EREaHONPRARINACT R EanbAERHAIEPORS 0 s -0 e B @fher anti-convilSant'drups s o - ca oo aiais seie e e oL L - o oo Bl fe . ale o . . . - . ..ot e e s e e e s e aa s s S e e s s s s e e s s e v a st el el alm e e e s s e 49 s 50 e e e o st o 8 e s 51 e e 52 e n s e ... .o SOP (standard operating procedures) manual . . . . . ........ NIH (Natiosal Institutesof Health) . . ..........c.cccevencrocccasones 54 55 February 22, 1990 Tape #8: Compounding PreSCripionsS: TEZTETL o dac g - - . . o . oo oo coc oo - o o e R as s o n oo s R Goodman’s book, The Pharmacological Basis of Therapeutics S oo R s 37 60 . ................. 61 March 15, 1990 Tape #9: e o e e BederaltFaod. D and €Cosmetic ACt Sulanilamideincigentl I R SRR e e 2 e o o < v« « von e s i 8. ek e L e e e I IRIERAREIIIE ASPEEtSIOF PRATMACY . 1« '« » = = e = ol oo e s alesasnenososonoss 66 e 67 e sisaa s e s ssae e s S s e v e e s e e e e e e s asonmaans 68 68 s a s s o ssnnamsnnsscsseeossdl March 23, 1990 Tape #10: History of the University of Utah College of Pharmacy . ..................... 74 " *Anticonvulsive Properties of Experimental Drugs” project . . . . ... ............. 75 TN Publications eP i R Rl Eptee I EEeS R e S ol (ot o 8 e st oo mnionialiel e o sisn o sy e e e e e e s v oo s s e el e 76 e w0 79 THIS IS INTERVIEW NUMBER ONE WITH DR. EWART A. SWINYARD, FORMER DEAN OF THE COLLEGE OF PHARMACY AND CURRENTLY PROFESSOR EMERITUS OF PHARMACOLOGY AT THE UNIVERSITY OF UTAH. THE DATE IS DEC. 14, 1989. THE INTERVIEW IS BEING CONDUCTED BY ROBERT MILLER. (THIS IS PART OF THE EVERETT L. COOLEY ORAL HISTORY PROJECT.) RM I thought in our we would next session grandparents. tell ES: My us father, Utah. and your came start with by the to Utah with a RM: Do you ES: June RM: And ES: That’s right. And one thing mother is she was a 19, the met his We lived in Logan. He owned you this country in from the state Swinyard, Halverson, was and company. She of the her was born Utah. your father came There Swinyafd, Chester Alfred Wilbur South Main perhaps dressmaker was was and were century. on of originally father My subsequently home can from England? wife. that Utah. Company and date your 1885. seamstress. Logan, County, and to parents--what Halverson handcart Marriott, he Weber to hame in history, further pharmacist Elinda family little your came registered Bertha a family father? Swinyard, a some back and a remember with go mother became of out can will mother, daughter we William My mother We about England start on Allan the Street to by trade and 184 South by principal boys in We because our all it for Ainslie thoroughly on about a my beautiful Street in Drug and about half William family: was a Main partner Ewart say City the store that Swinyard, Swinyard. ought employed operated four I Owen Swinyard, enjoyed huge a our lot-- large enough back and could baseball us. I baseball the ball went bread that my the She to and she said, the Now is that Brigham Young school Young The type High latter and teaching. we When one that?" hit." School in was part Brigham Brigham grades one to benefitted from the eighth Brigham Young College go I to a school shall city for I of used to Young Saturdays one school the to and forget that College courts practice High the In we campus, basketball of that tennis did!" boys went that just and in home the School. had marvelous they and I then year to to do at my it church block away we the by used gym or play During knocking was from over go to school to operated it’s a time, high thought a a connection, lived Brigham outstanding one letdown institution. at They School gone operated Training School having years. note play Logan after several interesting Brigham never the landed over "I church grade, the work. ran College, their discontinued the a eight. High to of Young Young go and said, of playing Logan. Young Brigham to were We All the play window Father the I had we mixing. discontinued so to in school? the reached gardens that kitchen been a good the all time the School and I used had high included included teachers, father Training of School, where hit had Training which of through "Who Young a couple remember really Brigham a mother said, "You have diamond with there ¢ we baseball in ES: a that the on tennis the the on weekdays, ball against a Foundry, I felt my I cement that was pretty early was next activities, later on the it and outdoor activities. boys the to oldest select brother, brother Chester saxophone. George W. enjoyed tenor Are I I Thatcher, it very, banjo My younger brothers were College, and was Agricultural State of the Orchestra. play I the best One tenor a time that banjo? learn the four music years and he sports enjoyed encouraged how play to and outstanding and My the with cellist, how My flute. studied learned the it. the clarinet, I of Utah mother cello. later one team. the for fact, piano the the you and to play the our member bands said It’s My in to the at brother me, fingered "Why don’t just like us Utah played Chester the of Young the at state, that older Brigham orchestra the All My skills. orchestra of about more trumpet. the musical the you tell played play? occasionally still I’1l but he team my was school then where guitar. College. dance and and I of was this violin, brother members on he much. yes, what high of an tenor the matter was contributed frequently one the on the Tennis a play who very say could I later. and to instruments these wish learned point to tennis. of played the me loved instrument played and father both William, Ironworks My As that an team much. point got played I played enjoyed to I tennis College. This playing and very Lundahl door. and music The comfortable Agricultural ES: building, with Bluebird you a learn cello, to and I'm sure band would money I that be playing played any for and Dance play the in a one When or During dance In this Bluebird ES: We would was play unusual not a night a dollars dance because Dansante we in will had to did was was with and but never bought considered a fortune Pond taught with get became gave paid, I pretty up invited his to career, years, him I because offered beautiful for it--two metal me to in the and play and Bluebird learned how professional job take with his played played place. on During dances every over to the for virtually I any for a gold-coated play make orchestra I had dance him, Therefore, involved early never was not I agree our I and Pong Orchestra, the over reasonable pretty You in and night but eighteen jobs. all go I my hundred in college another < Sunday. and you. It and I banjo Angus I Angus Orchestra, way were sit the thing, I wood. band, school of dollars. to plays symphony what Although banjo. high the services. inlaid dance I sort paid me teach in fifty Band. Bluebird my my invited who cello." that I hand-carved even to cello banjo. hundred happy and money tenor Pond the the receptions Angus for played Logan, in us The to several then what they We on a rates get to four Saturdays. But it miles away to became known was Logan? The used hundred built of Idaho. Orchestra Bluebird in outside into five and go go days. those regularly and you and state weekdays on job. did new well-known first dance as hall the known as the Saturday PalaisDor. night. interesting that they The best dance trio do a music. mother my As State sure that life although avid He loved I sports. him. down to the store and meet him ball games. This was when Logan which In Yes, which baseball. family, things As sport you the was I a of Salt would he have made he My instrument. would he sons his go to used we that his of part took new a between midway was KSL. on built he the a would we always then as to week a any had Baseball that? very remember closeness and first us take to ball professional anymore. don’t they he City. program music remember with came district, play and fisherman, an We Utah, because not did himself he member when business the won a and fact, music, Lake and times Logan, in an about Salt radio family, of room, music a had the and University we and matter a Gates. three or be recognized was one-hour Two Boulevard 467 on Utah club, ESS to in was also week for was I every talking contest Orchestra Cecil a I’m this state. hall might contest B. home father entered the evenings. us band that this since by with musical dance in that organized loved down seems Bluebird in once father sit the played mention, state band City Lake to it Orchestra Thus, string My a Bluebird place. Well, place had We as a well . . or. how happy we as to do loved and how we assume, was always family, were a together. grew up, your family, I active in the church. That’s we true. went work to when When other when had to work. playing your of He a Was he the the he We of the one the and church father drug but sense days would go to that had go church participated of country that He would sort the those store. we this in in frequently this at the My very to church only in could, came member in trios father member was Sunday us by active regularly. with he church were church every church We to to even in thing. from England, was he a time? church. in his family? Was he a convert to the church? ES: He was Did ES: a any Yes, as members convert other to members a matter of the Including the his of church of his fact, in England. family his come family or . came. . . They were all church. parents? Yes I Now ES: In those or days experience. after they experience, they what passed was one They the the would to any formal training examination in interns as where take pharmacist registered work would have a in procedure? a became progressed they he Did was he that mentioned ask--you pharmacist. registered pharmacy to want did they the they felt state were drug a they board had by store, sufficient examination. recognized and as a If registered So drug ES: and who Was there years as very active this He really ES: it. to ask were we Well, Brigham Young did interests ESE: away. have We have you grade school we to be my so homework, BY of buildings the all High the had and wrote I I when it your interest in What kind of in high in as a man young -- music and intellectual school? What sciences? student. that reviewed activities. In writing the Logan Eventually interested I was the good about College. toward a over took and just that. block you drew question a outdoor and another by just discontinued. sports you lived what that’s Okay, enjoyed? You down moved School he profession of Campus. College was pharmacist. enjoyed want did I a kind the Is Ooh, as He Association. Pharmaceutical State Utah that and Pharmacy, of Board State the of secretary many for served father My yes. time? that at narcotics of board state of Pharmacy, of the now not. a kind Board prescriptions fill could who to as Regulation could State is ES: industry? right. That’s in regulation strict was there point early that at even the pharmacist. went teachers, marvelous I was trained well. My through in folks the the and I was Palmer encouraged eighth grade trained Method me to training of do school with School, I I lost a straight was playing little activities. School ES My older the the in the and what we did, and became a of My offices. in taught was at anatomy at anatomy Assistant South Carolina where he Professor became and to premedical younger brother and majored College Agricultural I While with to University Medical of Professor of of at moved Anatomy, went the head of Lake the a took and Boston. Salt President and Medical the to Research Chicago Minnesota in east television Minnesota College Anatomy subsequently as the in Corporation went education first retiring career, of Hazeltine the in brothers’ graduation the built that majored older speaking am upon brother my by influenced go and zoology in My chemistry. Chester Tufts had discontinued they traditional the 1927. Young Chester majored technician the in High and Research brother Logan College remarkable a Hazeltine the Ph.D. had from Agricultural company the scholastic Brigham because and say, College brother he and tennis, Utah older research Laboratories, He my I High was sciences. interest playing from My Logan That was I believe I business. was into graduated College Utah the to went I got shall graduated in minored and I in, physics. the I Agricultural College, to went zoology set. in chemistry. I Alfred Utah William Young Brigham degree. dances, Agricultural Utah when interest the majoring in in for my entered minored Now nevertheless, brother College, to of But and A’s. then He then College in City Department of Anatomy, decided and he wanted University, in charge of go the Dean his M.D. children’s where Stanford University Medical Do you remember so Medical he degree, hospital California that the he of in became School went and division to at of further, rehabilitation professor 2 to finished children’s moved Assistant School. to for a is years was famous York. a member York many very New and New He Later of the he staff currently at emeritus institution. what years he spent here at the U in anatomy? ES: He came back to the Associate Proéessor Professor of to know center at the director to of this that Well, Agricultural met me finished in the as stated, "Well, classes, and I hall who you is and be first one have decided that but first I had a year, are not thing 1945. the Dr. James I of of said, "You I as did the to take I that of that Utah recall that English teachers are as in any Swenson interesting said, well is first director went couple not It brought the was rehabilitation mentioning. done I in then the you?" would and was one and was and before, worth day Utah currently I 1940; 1945; Dean also mentioned in started of He brothers the Chester University might Utah Assistant that I by your Anatomy center. as that student did." until College, experiences I of institution, center. when of Anatomy interesting here University not "Why?" She English as more fall good was a they English to sign up for college sophomore. and my up grammar, a I that teacher the and said, and now from the because thing that because fever was passed he from away would years to finish did No, just at a in you Now He my June work out the store. very lovely in in I work at college. the did I of 1930. I early one me left My away. year one was for thing best two take and this typhoid embolism. were store the in work May This the course important but school. that decided to and 1932. the front. However, girl, in still were a years. that pulmonary brothers older was unusual as time. the at in well, a of died He most me music many was far very go of This at your for was As along two so days fever. to the just said, dropped Perhaps early sixty-six I and before. away. to be do graduated once graduation, to me those My down a morning lived awhile!" played only looked time mine it. got and brother younger of and and was first who roll a had went he was he to I typhoid problem. big a I it neighbor many I that stopped and and class the He over in to my dance out course, called that me had be club concerned, recall, I with ES: had to many to contracted he morning was occurred father went "Here." dance scared year I He going class he us. danced are the out said, "I’ve of After I you member As turned street "Swinyard." My recall fourth pharmacy After during Grace part graduation my years Parkinson, 10 of and the I at we drugstore? worked Utah time full State decided to I met get married. our a We marriage summer on we for left school in pharmacy training thinking this University the State went immediately the work in in State life, namely store and operate About the last to join my the City Drug Company letter from E. O. at'Idaho me over the had their one of faculty. their I 11 in part The letter faculty, talked it and over in the with the I College informed they to Utah. Augqust, of to going was Logan, of Dean Leonard, College. State lost first I interest father'’s take City, went and what decided a as I Lake Salt Idaho as registered Examination, to or Pharmacy to from 1936 commencement. drove had I Thus, get to could known now Branch, for Pharmacy in Pharmacy in play graduated and this a for we Sunday on on Saturday, day all did I stay July a they fhen of received that and Logan, to of Board store Sunday school play could I the anxious so not back store. after Southern was did the then degree science I I and Well, Idaho, of that pharmacist do of University. took night, Pocatello. bachelor a with to back drive in work Saturday dance a for in and for Pocatello live my finish reason could Logan, to return night, Friday dance we very should My College. had was it I that they this thought I after because enjoyed and Utah State that Immediately both and afternoon, Friday could we Friday We to Idaho was 1934. University over, it at way through night 19, Purdue return we that important June pharmacy. talked we Then much. married me would my of wife like and asked to her do, and support Well, what I a telling him dropped She had She said, I that in the been on a "What and Leonard. came made in I in the fall Idaho mistake take of going to cello next City day her about it?" I over the store, do whether that but you her you get "Well, when you take that job!" perhaps the most mother about you and my You That important letter. never called home. can teach throw I turned it always get or not." Dean letter?" do, but the may to Dean came "I for? life. Store. said, like phone wrote Drug my told you will of my 1936 faculty State this your be the did said, I consideration, I did her his "What Leonard, throughout and want of for trip. up kind down in you He it was in said, the the start decision I of have life. the accepted the to my joined (now I wife the what sat The picked was do I stay do "You That over, mail. you said, lovely him would learn and basket. what So to "Dean yet." waste take over that did chance my short said, She you." thanking I walked "Not from that home do. support letter She another will thinking Leonard come should received after down." ES's I I at job of life. and to the joined the University College) in faculty of Idaho at fall of teaching, I made probably My said, learn mother with that banjo." you?" I As 12 I can a do 1936. "Aren’t said, of . . Branch When the you "No, something result . Southern the instruments have you that I biggest going they are besides I to play haven’t THIS touched these instruments looking back, was IS SESSION #2 for WITH DR. SWINYARD. of the second your session family. That to me, I THE DATE IS DECEMBER 27, CONDUCTED BY ROBERT MILLER IN HIS EVERETT L. COOLEY ORAL HISTORY PROJECT.) For years. a mistake. 1989. THE INTERVIEW IS BEING OFFICE. (THIS IS PART OF THE RM: many we are believe going we to should continue start discussion with your grandparents. ES: My gr?ndfather Swinyard. He Tunstal, the ES: where were working people. were That is nine born on his very more right. but farmer They and wages children to support, with the Were they of the They were in England as married Sarah After their England the for year Anne age he of a at worked in turnip. religious, and His hard- twenty-eight little and was very difficult England or and time, lived years migrated 13 in the a of the family of even to came to 1life. . then of various before to of 27th the on with they Alfred Church. LDS they had necessities the the children low, Brenchley they young 1836, very it of at of Jennings February, consisted their basic marriage, 1885, very honest, were Church members country a of Alfred type. as them was 3rd breakfast poor a side the At goods provide In father’s England. parents They my was Kent, fields worldly ES: on they this Swinyard 1857. December, communities came United to in America. States with their family in-law, in of and Logan, follow an a individual, Church. and I shop a to live in What year did of a very on very true to boy mother and Anne children her while short a LDS his Sarah taught after passing years, eleven Q 1896. November, the visiting but lived to religious of Logan. settled quiet, his organization and die? of 29th 1913. June, join family, grandfather’s your family, a was in the on He Center grandfather They continued West of 1st daughter- Alfred young She one Millgate. always States--about died his where various wife your grandfather any down the Logan away May was in as United the to coming he righteously. very son-in-law, blacksmith. served faithful very was Utah but remember blacksmith Did as one daughter County, trade convictions My children, adopted Cache his patient four the church? ES: They did And ESie Yes. ES: Now all my did. most his who early wheelwright came ES'’ to Do you He went was was trade. He a but fisherman accepted the Fredrick Simon on Norway, Once, in he youth by born America? was side mother’s my on to come then family the grandfather Halverson, In of 2, October became later gospel in Norway America. remember from what Norway year to that might Liverpool, 14 have England, been? by way of 1829. a and Copenhagen, on the He came steamer There up is gospel him, but come to in and her the 1855. They was about the 14th 1855, and winter. second on Their to moved Salt Marriott, Lake. families 10th He were of built raised. at with miles from in home was where In years. that a the in Marriott in was 15 a good March 23, on the on the Blind they Simon took were and the a married House here 7, first 1856 They mechanic cross September of of and to Grove, Company lived 1864 March Mormon on School very until Endowment the was her Guymon Lake ill, ship Kansas, spring and in year on they Fredrickson. home He the County, Garina Salt and very for from T. felt their Leavenworth where wife long care with He Gunderson, Noah in Utah, him Atchison, the Utah his the Saints accepted church. Kansas, Fort to became by to the arrived Weber Ingabor the Torberg then with worse Simon leave 1855. Kansas. come however, Leavenworth, Ogden, many to helped to the Christine and They to mind made handcart first for wife, March a about Liverpool February, When to bringing Torberg three June. moved located was left with of only of here. Bertha, near married 1855. plains her, daughter died Simon the was his left Orleans refused up mate, Simon’s wife made Andrea. ship thing He 18th New strongly Bertha A the very without daughter which he condition to 25, felt on from his America voyage. kind Norway, that England. Naisbitt interesting Simon daughter Hall, Mississippi very strongly and James the a the so Denmark, at two built for endurance. He made his household furniture. where Union the Ogden, Utah. considered depot sight before on of the was came. spike at the vicinity the team and and Branch Marriott He building finally civic affairs contributed fund built of Simon the many and five new years was in served and by returned the this hundred tabernacle after 16 was his in the railroads. wagon their in from in-cash He which had the of president Ogden death. a boarded prominent dollars left witnessed to position to and Utah, two very first golden wagon and they train this 1869. They the connecting He but the of Ogden, where paid was redeemed. team willows. Point Marriott. to home drove of grove spike they ceremony, the 1877. golden the a Promontory to rode of in wagon in Street a owing railroad 10, a drove Matilda Twenty-eight of and and church daughter and worked for He never May on Utah, Point, Promontory worked driving the at present was Simon later broke, the on The doubletrees dollars. were pass life He in and He went hundred which located of Utah. later land pasture. pair Ogden. who vouchers a to a and the marshy for for of several receive and except railroad Farr owned subsequently traded west sleighs, once wet value the Lorin to Grandfather After of was very eventually worthless never driving little Halverson supposed train very named some was construction Grandfather with land plows, Halverson Depot This advent contractor wagons, Simon Railway was railroad own 1866 to to the was only a few weeks of schooling reading and writing Halverson was indicated by and School duties by who his Norwegian he gave If I fact He the ask in he many English before as and for his the home children just a the wife he was just severed. American . left for . . in Did . . of discharged his He not the the knowledge court. did as of law He speak children Peace these justice wholeheartedly. in Justice at Simon self-education served years education Nevertheless, his well-respected appeared language could that was his self-taught. for country all and successful Trustee lawyers with the Norway, was very well. adopted in to the hear, and names. he have any further contact . No. That He died Now ES: on your wife Not my to My I am in which was not Swinyard, or wife Did did he your daughter a Marriott, you have Weber County, mentioned, more aware of was born Kent, Alfred mother than took two Utah. his wives? that any on did you of any know 9th of His England. Swinyard Christine and L7 these Gunderson. people keep of? journals. real the come? Torberg of question, diaries Sittingborne, mentioned, in Halverson, 1864. other The journals ES: 1901, knowledge. mother Okay. 5, grandfather second Through ES: January Okay. My October, parents, Sara Anne father, in 1863, as William I have Brenchley, already came to in lives. William schools of sixteen years In business, which in City the Drug thoroughly Company one of in in kind its of concerns 1903, not thirty years he the trade and secretary, the of He made substantial and of 15th September, Bertha married William Idaho, Pocatello, the On Logan. connected acquainted. strong the Druggists Sons feature no was was he which business as served There manager. and treasurer, somewhat of upbuilding he which in establishment the reaching Aftef became For Logan. the with connection in figured he that 1889 of Company Drug City the with in was It Utah. Ogden, accompanied he and Driver William with work did he earlier, own his for clothing the However, Utah. in pharmacist a as registered was he subsequently and business drug the entered he Logan, public the in America. to immigration their on parents his their until England in followed he all When learned he days boyhood his support. resided provide to out started he age, of settled England. in village native his and education his began Swinyard they where Utah, County, Cache Logan, family their with 1885, July, of 7th the on Utah Elinda Halverson. Do you marriages ES: to happen my in the to the youngest girl childhood family days and besides of Simon school were and days 18 any plural other Simon? Elinda Bertha knowledge. Not there if know was Torberg. in tenth the Marriott She spent and was child her very and active I in might was the add when in he nine. got and Drug November, his bride took until he his her parents. our family have and My a enjoy number of living stove to the our of he lunch used the room. ventilator and moved in? go was a May in a widow in sleep was room take at 184 it. was up or turns 119 we or in just sit looking that of father’s the around There to of the to take down to things canyon us as a above warm see home a above the and at are was directly some used distract my the which bedroom of was was by home. ventilator Eve not One happened let She occupied bought 24th Cemetery. home go the Utah. City 1930. twenty-two on does the which Christmas and a died it that of for if beautiful things were the Logan fishing sons on previously together there living On the twenty- four 8th of remember, City questions build or us to the eventually did to in and interesting room, in husband 15th the County, always We family. remained he to-operate Cache father what away I her where than the as made Logan at build picnic have She when already to on old, death. father built would Saints. younger born years continued Logan, Latter-day was husband’s couple your forty passed wife, have a was Swinyard I It was Bertha that her already years and 1952, Did eleven married beside you. some was buried just of married. William after Christ He Elinda, years Jesus 1874. Company Bertha of she were William born, ES: that they November when Church the air grate what the up off our cry as in, looked him over, off his eye left and left him he fell on indicated a of he was playing. example educationally excel. Another the spfing out on the clothes to shake I and has brother Clara’s. still never Bill He going broken a received and given went put and me his cut We air. he set the trouble. any watch I the in top 20 the of mower his my time the while finger. a trying off, well healed it mow thrown was Another someone turns taking and have to used boys problems mattress the put to our had we to continued he as Fortunately, arm. finger off handicap, Unfortunately, to over ground used mattresses off. other each mother to the straddling time great line the indicates that my when in on brothers his for instance was that Despite been had that laying was that two-by-four out study Further spike four-cornered his penetrated had eye. that in blind found he and doctor, the not could but him took she cry, to carefully, something that a sticking where continued called She examination close after he him checked wrong. anything find hurt. took mother My badly when and and clothes were he if to started he house, the into go to turned he when and day, one porch back the on sitting were We Chester. brother my to happened remember can I that thing saddest The problems. had we boys, young all Like close. very Absolutely--very, close? unusually were you that brothers as say you Would us. for tree the under putting was Claus Santa presents lawn older at Aunt blade was However, the the doctor was able Basically, average I did life want have the All I of Were young Yes. At one I not did and you at life--sports, ES: four ask or what would the she at have to art, music. Were there think I I be considered them in an have had any a mother hospital? well-rounded particular interested you? seriously considered going do your a that could nicely. home. seem time healed births--did you--you studies it boys. did born and as your daughter had on, regarding home were any in back for boys subjects it we boys there put suppose, to the to it as have some pictures switched from the a into profession. that I drew art, Both that my are but son kind of interesting. When you run school then ES: you and went or less or institute? to secular, high school No. 1In really you Logan did Was have High, the there College, the religious which church which at something was was there point to church- education, state that a funded have and and more seminary supplement the education? those felt would BY days like they it was did not quite a have institutes, and we letdown. FORMER EWART A. SWINYARD, THIS IS INTERVIEW NUMBER THREE WITH DR. DEAN OF THE COLLEGE OF PHARMACY AND CURRENTLY PROFESSOR EMERITUS OF PHARMACOLOGY AT THE UNIVERSITY OF UTAH. THE DATE IS JANUARY 11, 1989. THE INTERVIEW IS BEING CONDUCTED BY ROBERT MILLER. (THIS IS PART OF THE EVERETT L. COOLEY ORAL HISTORY PROJECT.) 2: us cost ten a going to he passed away, of what boarders in order started she money. We friends with became to went they while Boulevard 467 at lived who z individuals life-long some made and with acquainted some earn to was she So, had. she mother, my that determined was little care take in taking by individual, frugal very being salary When would it today’s father’s small. very was standards But that. times Boulevard today but build, to $10,000 like something cost the on up ours of home that correctly, remember I if back, think often I days. those for well did father My well did Company. Drug City the at financially father your that seems ask--it to wanted just I school. ES: One a me Give of girl there who Parkinson. We a an at school to going where Hospital she suggested and I see her met Grace, sister, I was the was that which and classical by she impressed I whom Agricultural on. I we ought to thought with 22 was how good lovely the date to drive a She College. a had Preston with Ruth, Preston idea. and was met, never to in sister her met a met Ruth of had had to I music, taken was she and operated maybe I wife? listening name the little. a sister, Utah problem, appendix acute Her way. Company Franklin dating started peculiar very from was Music bands dance latest the some your met you how to Thatcher the in while day as insight little When beautiful and I she was. A week which was a Logan, and saw he me with a if I he said, is you and a her person a from Willey, closest friends, go during time two the summer. We I had completed College in chemistry. 1932 I with my a continued were that school be I thought that will picking until for everyone. I She College was one of and teach school. returned By 1934. Agricultural major in zoology summer and a and holidays on Utah the her she that 19, 23 taking elementary June to was Grace married going Grace education. in at your while morning, Ruth. work did, from Grace her me I would Wyoming, She years. asked convinced with he living sister graduated Wyoming, to long elementary she When block Agricultural Byron, too graduation Byron, did in not love Utah him started her great then you I I was than from she for Grace had was If each so It rather two-year and Upon to school. and who surgery. deal, He ride daughters." certificate Armenia should my a school Logan the in in. in told through needs Street came school. I Bluebird, Main back When to good her the teacher’s education. of to lovely her the on now to she ride pretty was graduated a was lives and in Parkinson, day. just choice with This each her steady a store went from going out she Grace give taking cream Grace that Boulevard, like sitting me school your was Leonard recuperating to ice while to the sounded up told and I father, "Well, willing give later candy family on she so her drove home or minor session in that in order to Do pharmacy rather was it serious attended Purdue back to Pocatello University of Idaho moved to 1945. to return to Pocatello currently I am I would -school. of Board for Just a few one training in at 2055 Michigan few a say to children, whether had the Primary She Saints. B. Lee B. I minutes. question at Lee U.A.C. I board along wife), and wanted you that to ask is a wife great going studied 24 speak his accompanied think when that to back zoology, or was in General Christ asked was the Jesus on second (his Lee Sister Harold served on she church of Church the for that She went we in be serving of privilege the She it to move home Grace. place every had Avenue. about words teaching death President we and Harold Grace’s 1950 children, Latter-day Sister in order in the purchased and loved particularly in living like just active 1947 in Lake Salt to but permanent a made We leave. sabbatical my for qualify Pocatello City, (1946-1947) one year for we the at in Lake I then and lived Salt to moved then We 1936 from I where Indiana pharmacy We Branch. given and Grace Pharmacy, of finished I Southern even Lafayette, to where hadn’t After College University I died. time. that into profession? father my immediately went we other until thought married, some time the about It than go to decided you point what at remember you school. pharmacy a to go to myself prepare of with at consequently, at the and funeral. spoke also compliment. to your early chemistry, and the sciences. church Did at you Could that have earth? time? any How you did recall Was science problems that for with effect me the and religion evolution you, as atmosphere or you an the the issue? age recall, in of as the a student? ES I have never had religion. This About I was 1960 any problem reminds me invited with of to an conference matter sound induced seizures, Dr. Buznell was is called. and after we needed so that this the to we first have could committee, dinner, I change the bottled called physician from your does one Dr. answer was positively that--and I all wine a differ I swear truth, I from whether 25 a heard be of that headed we having were I could vitelle, which is is a and pharmacologist Now just very this--"My scientific, how said and answers, myself How myself. who it terminology religions?" many as Buznell if a the apparent Swinyard man at conference, our agnostic am other think it "Dr. from I when of ago. States this asked well-known about thought didn’t bottle "I question startled and said, said, When years on became Dr. and seizures, standardize over a had United of it member. for I science France, director better. a of audiogenic to Chance, that Paris, waitress England, agnostic? an was the session, Buznell religion was accepts of M.R.A. Dr. does the bottle Mormon." the communicate I experience of committee and water. out morning a matter represent worldwide of just the then calmly religion social, he I say philosophical, it." There Jove, I check out 100 or was like a long that." my I and verified If silence answer. scriptures that religious. could Much I had and is true, then then Dr. Chance hardly to numerous what it my wait to surprise, statements get I by we accept said, home found church "By to well over authorities said. THIS IS SESSION #4 WITH DR. EWART A. SWINYARD. THE DATE IS JANUARY 18, 1990. THE INTERVIEW IS BEING CONDUCTED BY ROBERT MILLER IN HIS OFFICE LOCATED IN RESEARCH PARK. (THIS IS PART OF THE EVERETT L. COOLEY ORAL HISTORY PROJECT.) RM: As you older grew up, brothers ES: My RM: Were you them socially? ES: I older have had close your to Yes. especially close. is that we it University every same next of house everything very see, my one brother reason, together for a was Chester who in The teacher. first lived I with wife with me, to live in. was in my that they used at many for and Minnesota, did really pharmacology. Minnesota, Minnesota 26 you do did were and on time. and on your the I he I Chester we at reason mentioned get to me the there went to went his and lived Strangely the faculty have at was years and were Another as year with I encouraged He me. things Chester we sciences, took I influence influence Did medical a of positive brothers? I year kind in as summer University The of a Utah degrees advanced what you? For of were previously, my You University ask on brothers Socially? the might medical in the wife. the enough, school and not in the pharmacy associations Degree I with I impact on Mallard from had my life. Hall, noticed the department be very had. "I; Ph.D. to the University he of Minnesota? I Minnesota, called and to me let see first Utah. of my know graduate I back be student completed the I on for a they get noticed a that at at I I in him and and the University June of to wanted Goodman student the College asked because at myself to State Dr. me told University the over with I the Chester wondered graduate Ph.D. I phone. arrived, first never Idaho at the visited what seemed pharmacology." was school position 2/ to at here pharmacology work They and Pharmacology I Goodman in book. man the School. doing housed, Immediately Goodman. is was Wright as of my his a Department thereafter to at the Harold and Chester, Dr. when Dr. it, summer to school will I am after in "You Medical brother, arrangements the what hall said, that 24, the in see July profound book to M.S. very medical the in on new S. mind of Utah So, came asked my down of a inquired He the a minor had looking a because awarded and that RP Louis was good, was professor "It’s I head Shortly him. made be that if in largely Minnesota the were good?" through going is major one." was of walking where said, author ran thought is my any without senior the was chairman it I experience I that Wright him. University an is pharmacology interested Dr. asked; in which I That through the then and to had a major physiology 1941. school. 1947. of It was one of Utah. You ES: of were the on the 1936 through kind of When I juniors, 1945; and Also, during did State a lot of research to them myself. The me. When I would leave couldn’t them could a in great What trunk the give them deal kind the of from years. What courses commercial was pharmacy which dealt sometime I primarily 1945 that from to of 1939 to you did were you that teaching I 1947. State, Idaho the Instructor Professor at spent as as to with later served from such time? come to up there and that research car and the food. was Logan down rats of did I reséarch I food; their for pay so reséarch, had to and I to That of by supported my care, them own care took visit without my buy entirely bring Idaho University. State Idaho at for water since University Pocatello taught Assistant you it was that had I Pharmacology years at I It 1939; of or the academic administration in animals; State, seniors, to by in the pharmacology. 1936 money State during pharmacy. those no Idaho Idaho Professor had awarded teach? to in research any involved I to pharmacy from at you pharmacy involved Pharmacy do did went and Ph.D.’s teaching controlling became ES: 1945 first two faculty courses dispensing laws first I would put so with situation mother, me has so I changed time. were you time? 28 doing with the rats at that ES: At that particular of chronic of ES: you Yes. at my went of the the of it it answered on the parameters it was effect of drug a very questions results of I that did that simple were Minnesota with that in work, Univérsity professor. therapeutic The on tripanosoma came to Utah of I would in paper I repeated equiperdum was doing summers keeping of I Minnesota. the and first effects mepharsen time University course State research? at of major research today, University Idaho the at the at on various at research was on degree p:imarily my doing research occupied with was time. the master’s to look but that publish Some for To research, important Did I administration administration. type time and do was my close ever I contact published subcurative infections in doses the rat. Now ES: you I Dr. Louis the of it. Dr. Goodman research. researéh, technician the and research, first Even he full instructor and major professor say was drugs. year worked I I that me. that and needed did I I was 29 of This was a help, great with the methods for area his to monitored my full-time so deal him in contributions closely virtually in finest area significant helpful very though help some the in the had I that Goodman made we thought to Goodman? anti-epileptic of evaluation Louis Dr. with worked Dr. would I Goodman. I world. wonderful a had Yes. with study to he of (1946). hired on a research We in it I When now understand we’ve got to together." was back to to wonderful physician in lecturer that, of of College The but had Pharmacy without in the Pharmacy at that 1947. I 1, of actually been in operation students the in pharmacy the faculty College came 30 on students of July had one had the time? been before Medicine 1947, 1, July The College in College the Goodman. were you of that of S. Louis Dr. that I 1947, support and of add might in Utah on as when it Utah faculty. So put to came any enrolled year. I will July started Pharmacy pharmacology when we College a thing title of me about "The I that in the Utah, at faculty theses." Ph.D. what scientist, and "Ewart, decide friendship there Was Medicine. continued, University the the joined you He experience. an truly the enjoy continued of ES: came That wasn’t then and be goingrto is thesis said, concerned he and down sit is do Ph.D. a for work why you qualify published papers to to done and As "Do Goodman, dozen a eleven the at Idaho laugh for now done work to research to started He can enough When enough look doing I get to work. Dr. to said I graduate return to have to leave, and I when going stop year, your was enough got you’ve I thesis?" Ph.D. a for any able be will I think had sabbatical my back in experience not and fall, came pay had I and work, this out putting were we because concerned became I that remember can I year. one that in papers eleven published College year, but been Medicine for one they had about 1, a 210 students How many in were the freshman there of you and sophomore that started classes. the College of Pharmacy? There were We Dean; Dr. Jack E. Professor myself, and a they and tennis ofai o was I honor of Dr. and Wintrobe the I honor, education. I Research Fellowship the Today $500. available, available to a This Fellow. graduate is gym old the just us of west kind What had year was Goodman. In $500 to that fellowships--well, sfudents inflation. 3 of Research that is I Utah which have Fellowship worth in me support to University previous Hoffman-LaRoche graduate a in fellowship Dr. received also also these by funded I Goodman, Dr. with student graduate a to That Goodman Fellowship. Research Wintrobe addition about do between. Research a Wintrobe was to . when 1946 a held you 1946 court or Dr. with building old the in were year continued in were We arrived. I moment I cooperation in work a there been because advantage graduate very building, with little and the from a also? work had we until B.S. a in B.S. a offer just point this graduate offer you only had I research is Hiner, Chemistry; at you did orbdid offered two. In David Medicinal college a as pharmacy ES: L. Pharmacology. Now In Dr. of Professor Orr, of three: $7,500 was one that that a is year. Let’s spend a minute talking about your two honorary every school degrees. I have been very attended--Utah University, fortunate. State Agricultural University of honored me in University honored me with in honored 1983. me with Professional Doctor an of Utah degree in 1986. these of Award 1987. Utah- Utah State of in The of Science College Pharmacy 1975 and University an me,with a of Award Achievement honored of that Idaho have State The Doctor Outstanding an I University Alumnus in Idaho another. honorary Award with and or University recognition the me Science of way Outstanding Achievement The 1984. one University the honored Minnesota in The College, Minnesota, Utah--have degree Virtually honorary am very grateful for institutions have bestowed upon I me. THE DATE IS JANUARY BY ROBERT MILLER IN OF THE EVERETT L. EWART SWINYARD. IS SESSION #5 WITH DR. 26, 1990. THE INTERVIEW IS BEING CONDUCTED (THIS IS PART HIS OFFICE AT RESEARCH PARK. COOLEY ORAL HISTORY PROJECT.) THIS ESis we At the time on the faculty by the birth of of their our first Longfellow, attended Wasatch, elementary schools, Roosevelt from graduated located Kasteler in on East Salt Lake City, the 19th of in Utah. June, 32 High Junior School High Lou 1959. 1955. She were blessed was born July and and schools These 19th 9, Bonneville School, married The serve to we pharmacy, Emma child. She 1937. of school Pocatello to back invited been had Rodger of June are D. was an important day 1934 that Grace have five lovely David, born Jeffrey, child born Subsequently at the Is there were 28, 29, 0ld married. 1966; 24, and the then four Washington recently Meeting she House any special was selected served Emma the two as why 1965; 1968; completed Utah B.S. where she degree. Columbus years a in Polynesian Lou of 5, 12, little at Reception reason a day Rodger May a and and born with years School, Lou the February University she was born After education taught Emma Lynda, 1980. to that Jennifer, 1971; went because elementary More at I too, children: she in School. and September graduated year life, June school, one my December born high in at caterer School, the McKinley and hostess Center. you selected the name Emma Lou? ES: Emma Lou wife’s named side was Emma after her grandmother. birth, ES: we the 24th Did he Ewart were of have is That him Richard to name. a a loving with 1943, middle in give him father Emma few years our son Richard Pocatello, We after Lou Emma who was on my was Lou’s born on Idaho. a found and in name loving mother. 313 We home, used a to Richard whom named service, we So, Swinyard. a Parkinson, church our name the chosen had Grandfather his Parkinson Richard Parkinson. name name? However, Ewart grandmother’s A interesting. Swinyard. asked and May, her Chatterton blessed rather had that because maintained loving say sister, that he we looked of like him, Richard and Indeed, I that look swear to the Junior graduated in mission for 1961. Church Pharmacy. degree in Pharmacy Ann They have Amy 2, Piercey, four Christine, 1974; has and Dee of Ann also of graduated 1968. they were "Sally born 17, July at the active in professional, Currently he is obtained majoring obtaining a her in degree business teaching in and Ewart, 31, in in he born met 1968; April Richard and SmithKline minoring a Science 6, 1978. from re- 1966. November 1968 certificate of 16, community, by he Uniyersity, born a Saints obtain December July employed to Bachelor James born served England, a 1971; he from with Ann, he Latter-day married children: schools, of proceeded While pictures Churchill. where 1962-1964 returned and some elementary School Christ Utah have Winston Uinta Grace, also Utah, and he of in fall I like High Jesus When He and Catherine remained service. the of University in did East From degree Dee and England. the he Bonneville High, the London, entered Churchill. went Hillside in Winston church Beecham. the University English while secondary education. I ES: to like would tried of values you in music, taking your family? Yes, we did were my parents. as know, up represent? to a raised you family, your Did you instrument, musical what promote as was in that kind interest the case in | but we were Emma not Lou as took 34 successful piano lessons for regard several as years, and Richard saxophone. However, that were more Amy, and Cathy, talents that Richard’s Do ES: your do so past twenty-five you a of on the seemed Three the time you engage I would say of my clarinet to be other grandchildren, well. So, the in family are prevalent my and things piano Sally, musical in your goes by, have dinner a the and so, if close Holladay area family? Do what kind of for you spend that with is which Glen, where wonderful family outings. kind of--as your you all we place did Brighton, above beautiful that, only Not them. meet children or a and this has and grew do with them? Do in the summer, I kind you do sports Earlier fishing. my in I life used to do always took Richard 35 with me. I a have to other in been have what up, day cabin have together a the we from hear don’t seldom is one by invited not am I that There telephone. by I by goes that day a September, this ago years Of of or huntingoriein:? ES: the activities family. close very very, seventeen wife my never also, activities in family is a family children of resided years. our my both Lake? in? is there Salt together, lost I in have consider do What always common live families Would Forest lessons family. both but there play were children course, music important. Yes, lot took lot of always a tried the to take my University three or of four Center selected seats been a frequent companion of ES: you still In all of the the fall husband. Also, of the shared an your noon I I mine "Super games the of all my the family his and at and in went I Fan" When Utah. of along I left on was teaching ten a grandson Jim has Richard and Dee with set an always after In twelve seats also given the have to same of the two the stadium for for the daughter and her seats the front These on tickets are family. in research, how a dimension of did that influence your home life--an books? example. there five When by I 7:45 days, then; and hours 36 a week. was a.m., o’clock. those now in seats my Theater. reading lecture or had that Saturdays. teaching have being until I members Was I reserved Memorial study, think I have with children? teaching, never which academician on have games. Pioneer freely emphasis Well, we football team of a about go? gymnastic row ES: been only at a Yes. As has as wife, my Ann. So events virtually attend of athletic Richard me. and passing the Since together. named constructed, We seats. purchased also was it University wife my I the first for various example, that at was the For ago games Huntsman to Utah. weeks basketball the children I it it actively 7:30 always was was usually, worked not just a matter Consequently, and until a matter . of I made absolutely a couple material I was 2 spending Did ES: Yes, you have we where I I wanted research as that Well, I that if research that I or to to being enjoyed I had with both. certain, I openly told out and report the family and enjoyed time being I for with my my primarily see teaching, which I family, with so and next the children that. and and It true to tell and you encouraged them the I very would I for check loved I fact that my answer Also, indicates is teaching know day. The them. go research, have not told their you best, would did such children? teaching I with your liked I If answer and involved individuals did my I that enjoyed them. remarkable say that is a if you talk to children their you trouble there day. process any the everything conscious would find sit almost them and would becomes questions. wife I been family by reviewing it enjoyed being this carefully has it; did day. following who me I to had ask room. review your ask next TV balance your think were night every sometimes of students it 2 to home home? with kind I at the someone available you and teaching, What don’t a teach prepared. the study consumed trying being teach good to and at called ask--as life. also to was becéme through hours we going in whole what to I was private light was of going a had the that ES: certain that father spent too much of time 357 accomplishment. researchers, in the lab. they you Often felt That’s that why I raised this question because you seem to have a close family. I remember University. will you do As I to him that not work, you to the We sold next store out We Have you I Because your at and have as of scientific as church a But this back to me what worked. subsequently It a used of number be was years had who Company, to it where to down then happened a city. you accomplishments and service, as your life? health and person a as researcher, throughout energy reported managers. the and time week?" and in who Food the much father. a Have you had health? been you of life teacher, a high end how much. father and of "Ewart, average time moved was Smith’s the an interested Theater, north as good college, your the look had generally Yes, to it know of your presidency said, me so various it then and Crockett had the a week. it was Vern they community in active to day my hours where Capitol sold achieved I in terms enjoyed it. and old on I Company Main tb need have because Then they in was tell 50 about away. later you was interest the Will evaluated our to one carefully Drug North 67 me University enjoyed City passed at it Maxwell called favor? the I Neal He a to recall, Because to me devote was ES: Elder this you ES: when were talking playing good with blessed in activities, about the it 38 your dance is early band high days every remarkable energy. of night, what you going and accomplished. ES: The most serious epidemic my two the About down with wear contact So even are early brothers them. RM: in illness were the it. at still ever had twenties. My down time I I do with they have was it, father and started some influenza I and was getting trouble my during the mother and taking care better, with my I of came hearing, and I lenses. your on age, that you same still get up at pattern--still a 6:30 a.m., high and degree you of energy. ES: Yes, I’ve been THIS IS SESSION #6 FEBRUARY 1, 1990. MILLER IN EVERETT RM: HIS L. Today My WITH DR. EWART A. SWINYARD. THE THE INTERVIEW IS BEING CONDUCTED OFFICE ORAL we going are and father the S.S. Utah, returned some from the July the for to 8, on on William Logan and he OF had declared 16, April was and THE Ogden, work in the 39 England in and Drug by Logan, of Logan William He sold. 1In on citizenship reaching Utah. City in intention his employed in your arrived and closed from his After was later He 1892, 1895. 7, of School sailed He Driver to Day 1885. business store PART Logan. 19, September drug in June 1885. IS discussion Wesleyan England, on citizen This Sons. worked continue graduated Kent, (THIS DATE IS BY ROBERT PROJECT.) Company granted entered and to PARK. Drug a becoming was HISTORY Wisconsin on RESEARCH City Sittingbourne, the AT COOLEY father ES: blessed. 1889 Store he Driver then he with John Bishop. it Eventually was well to incorporated his have the employees, that he had had something to and performed this store perhaps Logan in their when he the City was he also a South. made very the counter. After this professional store. The of Cache the the prescription Valley 1930. was member just Hospital. the boys was City at store go taken Drug had out, Store business of Although our 40 the also Main and business enjoy was the the Street a became doctors of a on handled home in fountain, it the empty-handed corner and of 1916 maintained a the operation but South up years the of Utah world the is treasurer He 184 it member the had managed progress only around to so other think a of business Boulevard. in up it two and I also partners, was all operated with lived of worked not 467 divided he one they acquired on with so efficiently continuous his him, they the the that feel during in felt them Association acquired for of as Originally common all served out he with and He along originally Second and he houses 45% in he he had He that he residence he how note Club sixteen, that made away but ownership Actually of passed beautiful another terms to that the Crockett Association. Store he shared This starting extent Drug and store, associated obligation. fharmaceutical After partners Vern gain important 1917. to and until this Crockett. each. Pharmaceutical Utah store 5% Commercial acquired some Vern 45% employees he 27th and and East it soda at more of virtually located some in distance a from the and City walked to work home The his So my store, all when he, work going to school after I did you start in 1927. passed for to me which Utah I I did, have to Branch, in Leonard which the from with it my work the I did. City the Drug at I in but other the the drug 1930, you you were also College. School, a my I entered time the in subsequently At of in finish minor be the Idaho, year, it obtained finishing Store. third thought was my a what of my wisdom drug last chemistry studied Idaho degree invitation I my store, year Bachelor financially University 41 He family. away to I would Upon University I full So, decided but of years before, night. U.A.C.? time two College. those the in back Sunday. his High spring that zoology night Company, the I mentioned finish at every other for then in and work College. virtually in other Logan the took night Agricultural Agricultural At one passed work and degree University, work to Utah In o’clock to and weeks 10 time walked dinner hour every Drug school and every from away. go work and City the Agricultural Science me at Utah started until had always forty mentioned, the the no worked graduating father As at lunch would you then When open always as to was ES: he father for Saturdays, began Yes, was father day my were partner--one Nevertheless, ES: noon There store next. Now Store, at again. days. and Drug accepted at of in at 1932. Purdue easier for Southern I returned of a to Dean teaching position, where excitement As ES a new I for discovered member, Initially I pharmacy, pharmaceutical going to stay I Chester He a he stay. home I in lived Then possible, my a throughout order major thing. funds support required cared for No at for the in This resulted "The Therapeutic back home, school to move was Pocatello. research. them. I Master of my first Effects of doing Science wife with and her I loved of during the as worked with me could work on I I in but my own in an the there completed degree to discovered research raised eventually degree. his rapidly started, I brother University as I was advanced school. work I fiinneapolis, and Pocatello. I So, to the which my stayed went if some in him Wright at felt master’s summer along Dr. year a course project one on at required I obtain Grace I pharmacy. finally with and while dispensing that but every come research school and and responsibilities? to started professor academic result off, get medical in pharmacy to I the the interesting love commercial needed rented took thesis I summer the summers. to your and the it this first I with he We Minnesota. design me that in great courses: law, putting that that a were basic teaching, kept was fed it insisted parents it. in what three motivated had and taught enjoyed degrees. had teaching. faculty thoroughly I were animals the no and work pharmacology. scientific publication entitled, Repeated Subcurative Doses 42 of Mapharsen This on carried department, Was that Yes. my Now that joy in did doing that majoring went when That not published until in the spring 1941. of you was the way Did you ever how much work, you did right head Rat." of the professor. 1942, you did in from the thesis? of another I received enjoyed teaching. find same you the teaching? the start. crucial year in zoology and question about your life. in I loved both originally were you into medicine? No. The reason pharmacology; my University the at That brother father’s your with me that was degree Minnesota at I Minnesota loved life itself. 1941, Medical 43 i went School such time, that after school in that because thought going. because is of was medical that M.S. my was temptations for to then and have rerouted? yes. any have you route you medicine older mentioned You Did into my 1930. the going of year was medicine. sort the chemistry into when of ask intent, my as a were was receipt discovered was major was went you intent Master’s experimental to be to my in research. wanted seems was who your research and who Infections for research doing just death it Dr. Wright degree you teaching the Dr. previously loved an Hirschfelder’s name, and Master’s It my Although had I Equiperdum accepted You I Trypanosomal the of going field next again of the Following the as summer with the to full had intent an of experience Hirschfelder edition Louis of S. The Utah College the of was that the pre-clinical better people. institution State Idaho either one lived in just the off a matter of the University the with sabbatical year, my wife apartment Elizabeth anticonvulsant and in Street. field, I what moved was Dr. which 44 or to known Goodman was of with had this to from leave that Quist me interest I would come Lake not could they would as for responsible replaced Salt to attention called I of accreditation first and a am I time that College understanding salary brother since day, sabbatical a gaining After my student. the that, to of get my Goodman Louis of result my an of of be to needed going never about the by Dr. currently were bringing was Ph.D. at I first University help school medical who direct the would that fact, of back pay least a better. done have was me other the the Therapeutics strengthening and instruction The I first just of Gilman. the committee, people the fact in before, Dr. copy told me Through a of Alfred told reading was me brother and mentioned direction. Basis Goodman’s Dr. As the my book. conducted that my have showed Wright history here. Medicine Dr. I Pharmacology reorganizing were they of this I man Medicine, and Incidentally, changed the became I Chester, As Pharmacological of without Ph.D. Wright Department Hirschfelder member Dr. Goodman, the a that and head Ph.D. doing at back where we Gardens working to him. in I worked Dr. hard Toman, fifteen I and went and join on fourteen months I spent residence to my because back was from Fellow. he as me the University when thesis back of I the and was afraid of at to University medical that Lecturer College back of of was of was soft State back Utah students he I Research at that up a so the first my I would in them give when position, finishing Pocatello how acquired Pharmacology from order drive to lecture demonstration. Was ES: This that on a was on about experience failed to weekly under sit a a basis? quarterly basis. remarkable teacher. the lectures through all 45 I wonderful had a Dr. Goodman no matter me received that During in the Winthrop sabbatical, up and put realize so my and in money and also stay to Goodman a I to have that Firm When professor not money Medicine. Idaho pay in me would Dr. the finished assistant that I had we didn’t words, student I wanted they 1947 during University. When an Goodman, sabbatical, Pharmaceutical I Utah my position mention graduate title as said other a was the to lecture 1946 should teaching and to in Winthrop Well, gave year I the working campus He the Goodman another was--in from research. money on at back Dr. Dr. publications research. thesis, here money pay my Medicine. Well, soft to and my of money budget. hard thesis faculty College in Pocatello writing soft productive. produced his the most I on was was and back worked actually who never was there, and then individual he would afterwards have and a tell presentation--a great in in the spring students who ever pharmacology first two University of interesting 1946 they thing the Utah. dean of responsibilities year. a During faculty for for a position was supporting resigned after work at Professor L. David and Dean the year the College of of to application. Idaho E. Orr I can in on a the from fall of the not have the for the a first selected application bet that Dr. result of in down spring where I was was of for I Pharmacy. as named was Professor was Dr. selected institution same I reported 1947, of Goodman that the and 1, and the made College the very I University State the the University July Chemistry, Medicinal the of took students came Utah at his degree A In did University year. Ohio they As State of time. Medicine you one from school 1947 Ph.D. was Ph.D. Pharmacy. and my improve Sugahara. this since of them, from Dr. the could I a pharmacy 1946 school Jack was pharmacy Pharmacology Hiner Dr. a he 1947. about with received received other the the of College University of Professor for my the the the how I However, with from 1947 the to.have of him teacher. happened decided University dean, Utah; conference of Pharmacology. So in 1947 the College of Pharmacy was established at the University. ES: The first enrollment was in the 46 fall of 1946, but those students were enrolled under actual College The Medicine. the auspices of of Pharmacy began the College July 1, medical school or B.S. Pharmacy? of 1947. A separate. were We separate That At were college? separate a you the of part considered still you Were is program, and you offered a in right. that time did you offer anything beyond degree. Let a B.S. in pharmacy? ES: No, it.was a regretted a arrived, I was I the students I minute was been his to great of well a University want much College as B.Si making as collaborated never I five-year as on that a part the credit that Dr. prestige I have his From can since been for say I of to that without that. It with cooperation to I time I me as medical Goodman there and has the research was never Medicine the Dr. came that the College lectured I period I say students. and Goodman and the pharmacy research, Utah of Pharmacy. five-minute of change. me funds. because that of was this possible. THIS IS SESSION #7 WITH DR. SWINYARD. THE 199015 THE INTERVIEW IS BEING CONDUCTED BY OFFICE AT RESEARCH PARK. (THIS IS PART OF ORAL HISTORY PROJECT.) RM: I want 1947 as to start you with served as question a a Winthrop 47 of DATE IS FEBRUARY 15, ROBERT MILLER IN HIS THE EVERETT L. COOLEY what Fellow you at did the in 1946 University of Utah. You did connection we ES could Dr. some with some start Goodman work with had outstanding traveling a a review commonly the that of federation meetings. and He felt the he returned to in Atlantic City, me to the the and Gold, Salt I and then then up to to Indianapolis famous Parke-Davis in I met institutions. all Eli in after K. K. University and the During outstanding that visit 48 I met Harry his University very the with to personally Finally Chen. recall Cornell went I of pharmacologists I area, Michigan, visited then for Gilman. Alfred where Company over York with visit some Although Dr. Kalamazoo, and areas, with were New friend I the their appointments the Dr. 1In to Philadelphia, Laboratories. Dr. the and of for meetings to in going country. in there were held the his Basis acquainted the in pharmacologist with of Bible." Society become University Lilly I Therapeutics faculty Perhaps result "Blue and long-time these a the American Laboratories Upjohn Northwestern where as Laboratories his Goodman. as arrangements Yale the on to to Laboratories to Dr. in trip. Goodman City with country Pharmacological should made French pharmacologists to he visit went Then Lake Winthrop companion former that The the I with pharmacologists to University very that outstanding SmithKline Dr. where the reputation Experimental of visit of referred year, meetings Pharmacology did entitled Therapeutics, spring you worldwide textbook around I the went Illinois, in well those talking with such outstanding Tainter, Carl Maurice Pfeiffer, Louis acquainted in this had a be a Seavers, T. Lasagna, F. and with at tremendous result of thoughts a health science the as I It was of a series with had was in the of education a lasting seriously as some well as of drugs in to scientist. to share As my and throughout experience, pharmacy impact 600 me the I seventy-two engaged with area some experience pharmacy, colleagues of pharmacologists influenced inspired pharmacology, Axelrod, personally a dedicated particular area evaluation well life. that of affiliated particularly my me That result I I on time. my not am particular made M.L. Richards, Julius with This result Chen, outstanding most about dealing until K. K. the experiences pharmacology. long K. R. education first publications Gilman, Modell, This as feelings As the that Walter others. influence those pharmaceutical started of teacher and country. many as Alfred Putnam, some country a dedicated scientists on in and me, and it research. publications was As in a the scientific publications, pharmacology effective in and the techniques management for of epilepsy. You also might confidential BS: As a result 1975 I in addition you gave me a list of 134 reports. of my centered interest In mention was training on awarded the a with Dr. evaluation contract 49 by Goodman, of the my area anti-epileptic epilepsy of drugs. branch of the of National the NIH Under to this from chemists if lose the to go all "Red evaluate. have this report observed date I compounds; advanced might of those study have gone have written and all the that Laboratories the effect body. If phase one with RM: would in Philadelphia they still studies the I going medical most to in then for toxicity look good, man. The school promising ask-=-how on they compounds it 50 come sent that As of 13,000 to the 2,000 Consequently, on point to that Hazeltine of determining systems subjected branch around has the in the to contracts country evaluated that I our out the then about a a over subjected are to call is of not and findings various are will compound. purpose epilepsy hospitals did Book the to the we reports sent the then what program. interesting are they percent confidential be promising chronic thirty 134 solicits supplier evaluated been five our the their have have through than of where was way It look 2,000 approximately more observations. those some we NIH promising and of Stroke medicinal Red mechanisms that the are then The and drugs. effective, sufficiently evaluation mention and compounds them. the the be of assure program, about on in are this written to These they through is They prove them. If way confidential ‘we to branch industry world. compounds rights Book" the Disorder anti-epileptic epilepsy pharmaceutical their the Neurological potential the throughout that of evaluate contract, compounds me Institutes in you humans. applied for ES this I had a matter published this of serve in and they drug On well as was approved and it was 50 was this study was being Drug used on the was a visit could be of did The benzodiazepine. S5 and in neuralgia, epilepsy drug asked that in the a made this country; firm drugs which and branch not they that drugs. antiepileptic two them 1978, with this, find this this determined (Tegratol) trigeminal in that controlled new was supplied pharmaceutical single they I Europe, firm for country, use committee discovering carbamazepine for that also to valproate Administration pharmaceutical not this for in me antiepileptic that work Institutes looking new Administration It After true used invited in as in commonly available Drug development that promising: (Klonopin) and a efficacy be patients the during and to every of on was not compound. of working looked time Food there However, Food privilege found they been its medication. available not was and, valproate were had is drugs they epileptic It work? National the on the the help information by on They research percent detailed committee. but this most and of the of of basis my approached approval the the 1968, 1960. Europe do work of branch there since one in to anti-epileptic initial is could discovered in on epilepsy they contract the advisory which country. over did established their used the papers I The introduced being got Valproate was on ways as fact, today. Health or many country. drugs of contract that at that clonazepam then made arrangements Clonazepam of to test was found generalized Clonazepan be of seizures. "Now do on obvious own. Why research one is a money knowing years to it a a on a very two least epileptic last new of of set three up would million? The largest market. The and in 1974 decided that cost to the annually? put it NIH they program. 52 is the neighborhood branch establish is at market in epilepsy put anti- entire You two market new new you the clear. would a on of got sales is $235 Would you your twelve market estimated had put development estimated area? of approximately on you this you ten it their director the if was of in would you partial drugs, wérking to wondered, firm where answer the take the would have they the found complex program where money that knowing a were dollars drug Or, you and billion this firm would where and the was antiepileptic firm, your for Carbamazepine new If it agents choice treatment seizures. pharmaceutical to drug put anti-ulcer you no have today billion? year, $155-160 Since the partial accomplished pharmaceutical you drug drugs in tonic-clonic simple. Would new complex pharmaceutical that to had would a half the clinically. effective and development anti-hypertensive and compounds epilepticus. develop million. be of do?" wasn’t of very they they answer to generalized we the was The in After what working also status effective two tonic-clonic is treatment these would put recognized their own of it in this In the Penry meet spring was chief with me. He I decided for the to currently Dean years he I to was knew would is because was note, a the had be sure I could that if tell why you and awarded it to October of 1974. had a become they that work I three worked done--testing did was standard important the way me, was it 53 a couple of me an RFP, amazed at it to do do my solvents, should to be had up, I it. I proposal. from they in getting making sure as well done, (SOP) said set unofficially just I it been has However, months what pleased applications I was proposal the project because had in very would you drugs, I sent this way a indicated was procedures operating to He for our for He animals I to administrative I 165 the started I because country. the asked development submitted received around me. how and instructions my 200 the he they that and request the in drug reply. sixteen. agree scientists writing with Kiffin request me that from some don’t various we use with later everything to a told and proposal agree learned preliminary a and Pharmacy. would Dr. anti-epileptic do team not these me He of down I for that do you followed said do new could from branch sent of research going however, I stepping I was he College a call anticonvulsant sure request he if request. an not a epilepsy me that of I received the asked responsibility. which of initiate I I development respond program. that 1974, who proposal would of A manual. served as a as SOP consultant research for program satisfy the that I of if new a way that I to first 1980. for $1,650,582. we received $194,019 November 1, contract for through month 1983 at a cost awarded a May 1989 16, project received various to be a for from at other numerous projects, the amazing. I it such brought which to mid period April to 1994. April 16, awards pharmaceutical reaches until then from we received extended we looks I a were program that a 1984 then one We 16, the us us 1989 fund When research time was 1975. for 1983. carried which of funded contract contract On figure in That January That that at the 15, to felt it standards in another $5,905,853 May own development because drugs 1984, $78,789. the requirements. through This I organize brought contract for order me, for $1,455,411. us in their success. awarded April through then a for 1989. of FDA get behind better evaluating for contract and the carried 15, had It $3,574,309 April I to SOP program program. was to a decision, it had experience operate were This their write important started 1981 and satisfy contract In who drugs, our necessary companies that to very into officially Our With going a two order could be uniformity We in FDA. was or antiepileptic proved were one from at that have industries or approximately for $15 million. That in is writing proposals wanted to and issuing 54 ask how much reports on time how do the yofi spend money is spent? ES: My Is that secretary name. NIH handles has University. never a with on this and that as In the I the project, I expended. You mentioned that originally and you were Has the NIH have the using is is The school of that on that but There may and large by Stanford this I of had any of you of our I principal do in kind? They is are program. There Liz Dr. in terms example, Michigan. that research. this for it with applications, what in is working problem area One, my there been 165 doing is the have that? sign properly, University. grants is the drugs developed other be of this evaluate project books beyond University working is were in justify do never projects. were the Teats conjunction be may not way they aware spend money. that mentioned epilepsy. state terms a of market, it but companies, was how not serious is problem? the If of entire we Utah, very is problem medical of in pharmaceutical to medical percent the specialized at appealing this program one us. their You the techniques with of, expanded medical another who contract to to money there the some the have institutions have years awarded other I the fifteen were They all spend funds having government audit the at ES: long problem. them that, auditors As to how of ES? important have serious population a that million would 55 of and mean because the about United two States have in a half people here we have thirty thousand people with should be able disease. We For example, the way trial of In these for ES: it do you use? We use only And or that this country were to done and on FDA; A an with a this that FDA number some 200 sixteen. It a is not gone all to clinical has approved of epilepsy we have subjected the condition connection. others experimental the use in drugs have the from going be the and is a disorder. country. proposal mice of to this is This progress program in could is real submitted use state. It tdelve our original thought ES: ten they this control. making in mentioned in are been used the to through have being epilepsy are basis. branch you animals, What and kind of you animals rats. perfectly adequate? Yes. THIS IS SESSION #8 WITH DR. EWART A. SWINYARD. THE DATE IS FEBRUARY 22, 1990. THE INTERVIEW IS BEING CONDUCTED BY ROBERT MILLER IN HIS OFFICE AT RESEARCH PARK. (THIS IS PART OF THE EVERETT L. COOLEY ORAL HISTORY PROJECT.) RM: Today we are going professional ES: In the the as fall of instructor thought that because you know the begin experience University an to 1936 of I subject to accepted you were emphasis a Southern was really discussion an pharmacy. teaching had with Idaho in our a lot of 56 to I teach teach the College work--a to your teaching. on remember prepare going on position Branch I of faculty of Pharmacy originally lot of and you and know of work had it to 3 thoroughly. Despite that to I loved dispensing Now this experience in my what me indicate substance, a of counting out volume. Very taking the At prescriptions that powder into what folded that had measure It might into in experience the job privilege and and where so a teaspoon and do it joy So well. to have been to was pharmacy teach 5/ or I these me, just found a individual a liquid that in that but my what I was students dry divided individual it The dissolved substance the the as might it right of together is either compounded. perhaps the It compound in take challenge the were that ready-made and they oily let capsules. to substances an time, a majority be not for out have do pharmacist shelf the my the off to of probably or had chemical real not teach jurisprudence. powder, capsules emulsion retail a into been is the to particular triturated an a to filled were you Today (1937) learned because pouring prescription have that actually either three into presented or they powders The or it be one time were called two converted do divided packets. at that number soon and me Since liquid, right that to then we liquid. this had and the seldom for differences. right prescription. ingredients like be very pharmacy, prescription it I assignments store. was few whether a matter first assignment father’s a work, commercial pharmacy receives hard My a natural realize seldom teach. pharmacy, was just that into had the to could form. So, past needed a how do to great to use a be prescription balance trituration to go if into became a very whereby be could make recall a that my to Do students my it a lot more when it receive much instruction I indicate into teach to that palatable to and how various you patient. and substance their today for these pharmaceutical might be necessary used teach me to of my artistic use this some to talk for teaching pencil drawings The and making restrictions under addition, 1In which pharmacy that and Jurisprudence you placards course . . but it understood which pharmacy was the practiced. it was allowed were required students 58 of .? which the sure art abilities. illustration display. the past? be. commercial and painting primarily to in inSthelsiiquids) things few a it way the like put to how the of something that is or to and this so that actually doctor out responsibility used a the was responsibility my was of make nothing It with tricks doctor I I substances for when were remember of the preparation bit can that pharmacokinetic written .by is Was ES: and learn do They was I solubility consult by substances liquid. enjoyment to carry a three that doctor. a compounding ES: it or the as little order So manipulations with a in patient. to incorporate little greatest put how in desirable pharmacy we students into suspension prescription the or to two increase more got practicing him a how were capsule could in I there interested you might and laws Basically those it students only with you was idea of make told rewrite it a little note couldn’t it to out to save into teaching, this enthusiasm it, himself back was "I I into a sent it asked liquid, but back the if doubt that put same one I would you the of The gave he in ingredients went originally believe I and with relationship students. At ES: The in that in the of counseled with procedure to wanted and of kind What an had the prescribing was doctor the he like pharmacist role did the in the role regard? pharmacist compounder feel pharmacist sure medication? correct serve make to obligation the did time that the those he but patient, with wanted the it was It prescription. counsel how served days it a was doctor in compounded. 59 the of seldom that very common regard Since I a out." when my he it enthused very to make number give tell, could don’t not To I He was in as not a back. misgivings became into getting it same apparent was near cofildn’t the not recall and sent swear I some soon I read God had I Although So and imbue physicians. I as me. said, got there it. did the dissolved which it. I because couldn’t He it read prescription I to interrelationship, had, be try time, who it of with that doctor me. on at to way also in him for but things from doctor, me, professional ingredients couldn’t responsibility patient prescription three a the some my to he what that he time there has patient Yes. been is class one the Back list morphine of the Is there Of ESi: is Let’s get Well, I back as serve V-12 The ES: an grading the but the such much that as for was as in was now the have history drugs? a control codeine the and time you about extensive such it At system as medicines over and 1940’s that more agency that what criteria is class a and assigns a do they use? How or class four three Drug a class to a do they drug? Administration. teaching. three courses of I in instructor have physics. At an we but that 1945 to I time in moved advanced 1939 mentioned, as time was From Pharmacy. courses I and Hall, Leonard served that About 1939. to and to I not to started we a the had program. V-12 During the 1936 Professor taught know substances your E.O. you wasn’t Food those from building, only the to counter substances, that with instituted. this by the substances. Do there and taught Assistant of were that instructor new five? consulting pharmacy. with controlled, drug done soul deal government particular establish of course controls a and controlled days were Today controlled through those change. to development in This the of substances. ES: have have a big heart you you there of the Now then a program? World V-12 War program. most II A lot universities of the 60 required were students in this to offer program were of sent the to the courses Since I invited had by the really He in room learned more Did do This went on teaching in in teaching in this College of have ES: to me What an Ooriginally was know to around the formulas. the some described of faculty these of the students the I enjoyed Well, dispensing me convinced I One order wall think doing I it. years? years. of get but in an mathematical all did, ;s the blackboards of serve principles. various was felt of they I who all area have all to get three to physics, One if My time. I going was course I brother to stay Earlier study of University the However, training. highef my pharmacy the that continued physics. and all I of which Utah Pharmacy. first the it I to pharmacology needed physics. was department jurisprudence, to a mentioned 1940’s. or take in physical number broad history led Was this I finally book, two Branch. instructor had did than a of on were it eventually Chester We for closer moving you Southern courses type I pharmacy, commercial was physics the deriving for to of the about this required based in Idaho of there them of number things where train you was were enjoyable and a physics that very a were head know formulas ES? they taken instructor. to University edition kind immediate McNeil couple of of of came out did that first impact and Company 61 set agreed and Goodman which success and times the in Gilman’s early edition have? standards? to publish 3,000 copies of that book. material to because The them, it was company wouldn’t they said in those if they had When of were you and I on them one When be in there to was listen for in never doing a I of had with out 3,000 was it when they copies, a and terrific price indicated they would in matter a the anticipated. them Company out brought publishing they which sold kind taken not that publish of weeks and how all anyone job he? who of I be meet the of was didn’t at to a in with improved I shall whether I had. the staff back was the individual that work Goodman would the it row to usual and their have done, I interested say, it a staff of member over was ever his of a register Dr. have I there school so, have Minnesota. most have teaching, 62 as was when could they and teacher lecture to seminar Goodman teachers would a Dr. them Likewise the take doing from class, a Goodman superb of primarily did although Goodman In you courses teach him. Dr. Ph.D. outstanding After seen your take had to them with put copies, that classes go him. to on what most presentation. have so Dr. teach, as McMillan They you hear to procedure review his would he out along copy those mentioned if the go Gilman it. because of get They a Dr. large to book. sell Did teacher, is a working courses. for $12.50 book. reprint you sat a for the research, few size. and to as decided the was days wanted twice finally it Goodman they couldn’t to Dr. about reduce anymore ES: When be his own or whether it So example this Yes. one Another when He be he was would the So he He was would in he When you knew he would on never he faculty. you? impact risk did me He impression students. on is that a mistake. know the answer that up would that He me making not look class." the not he didn’t and I to will guess. knew? give them the everything. the faculty what was the how was it and his great "Let next the a If say, give with joined ‘Pharmacy, had our never honest idea that would of impact questions.. he you members a great teaching to School had invite it the thing question, give of in 1947 beginning divided in the College curriculum between the for three of the Pharmacy faculty members? ES: You want to class that of had us the was to one teach sophomores. senior that I third year. precede there the as year Also Goodman. year all taught first that at Dean actually Pharmacology took at were no time time had years time before was 63 the a had the three freshmen prepared was for one and a that jurisprudence, etc. during research with Dr. my to taught Orr we came, make plans pharmacognosy; taught Dr. for students we we pharmacology continued as started, when work dispensing, Hiner that first So, class that that two it along. at well pharmacology. when the Since subject, course. It remember we that one-year into the had to chemistry. medicinal got for pharmacology. course. We had a laboratory hour with it laboratory throughout time the teaching You were and in They to How students We by Did you The first couple students. take to two of a weekly every three week pretty much a full- me. in mind, the the School but I a College have B.S. in in then that do a I with of Medicine of was still Medicine, the giving yes. college? Did you pharmacy? again Pharmacy of At point Dr. and take on Goodman did you develop we only had graduate a time when a graduate every work medical of I with would research. between College graduate his did we original the graduate pharmacology. would research was on any required in they on some Goodman closeness the not taking and The it first? project year because at did Dr. research a we started time three College degree years working publications what became for in you Pharmacy. of emphasizes in that At or College lecture That keep did beyond and student had Pharmacy? offering but students we Yes. go students, of students of students 210. had both reality hours year. separated, off in responsibility lectures many four school College were that plus teaching the start so used me in result to the in This pharmacology and the Medicine. graduate program of pharmacy? ES: Initially There came Dean students Hiner 64 started in pharmacology. taking on graduate students in graduate work So students these pharmacognosy. in pharmacology in the pharmacy who would medical Somewhat and later medicinal doing the receive their degree even though offered chemistry. were school we graduate work from they that would do in department work with you? That is right. I pharmacology. Do ES: you remember many students léng the If my in the Was was expanded as the for that teach me the several the would and what nurses years. program go the correctly, in through pharmacy the program, requirements there was a how how were? total of 210 years. program four-year five to started wés, four-year to with that had two a used you serves first it serve as you memory a Then did program this Yes, I also to degree get to your begin B.S.? with but then it later. B.S. they practicing could go out in the community and pharmacists? Yes. During those program ES: In those serve. old gym Pharmacy. Center. first years did they would go where early For years example, building, We Later we would we had we a we when had out had a number were on the unit they second unit in intern work? ways medications dispensing 65 of of kind any actually and dispensing dispense a have you could floor of in the College for the Health the Union the of Building those where days operated To be out to to two years, a When you Yes. B.S. mention 210 other wasn’t of students who to old into work. Today it At takes has ES: are going discuss the you and your When I was had it very the were pharmacy the to role of go impact appears they best from only part a of four-year that this popular. University school two of of Idaho pharmacy schools contemplated back of from Pharmacy, that pharmacy? in Southern in this California, going to Idaho many State school. a little that feelings returned College require time the gone students you to that IS SESSION #9 WITH DR. EWART A. SWINYARD. 15, 1990. THE INTERVIEW IS BEING CONDUCTED BY HIS OFFICE AT RESEARCH PARK. (THIS IS PART OF COOLEY ORAL HISTORY PROJECT.) We did We building. could or 1In campus. hospital THIS RM: lower students it Pharmacy another there here on pharmacy, college than Although came in students, area. the the admit in profession there still would year. medication. program. However, Branch, you a in directly some a them student was program go about five-year school the before but particular ES: to have have dispense for school work had to pharmacy high had would medical admitted of They the a college ES: we summer towards spending I was pharmacist bit 66 time 1934 at today Purdue and had on pharmacy. a very could in in THE DATE IS MARCH ROBERT MILLER IN THE EVERETT L. summer enthused actually at Purdue pharmacy about play University in the and over- the-counter drug sales prescriptions. great I interest as remember in drug purchases would most benefit of McKesson had ability of a an customers’ western needs that and spent a inscription the Grand Contest, that in the trophy, on "Awarded it, for October 6 those Pharmacy but got of Science degree. about The This that Federal act commerce the I not also College and only at at the that I were were a very and required that drugs 67 the guide the a directly result, I following Winner Selling of Spree should mention who were as a result educational I was University of of of Southern my changes the College Idaho got with Branch Bachelor that of took place important. Cosmetic Act marketed standards to year very As I enthused lot that Swinyard, eventually Drug minimal how that working practiced not Purdue Food, meet or items of pharmacists University where There A. 1934." of over- I was the a their and time of developed respect McKesson license remember Pharmacy time had 5, and fall store. Ewart majority a of the it to experience accomplishments. I into November acquired practical lot Salesmanship, to days had training came silver Prize practicing of who to monitor direction. customers large with properly had with the right with a 1In contest I them the about won fall guiding them. to compounding customers and sales the in enthused the in that our to individual as well assisting the-counter be well of was for enacted in 1906. interstate strength, purity, and drug quality. that particular being This time supplied to to amended require the to prevent make a rather was solution than as a dissolved the dispensed it in that came on the Food and be to that that Act be was safe regulating the which In 1951 Another the words, other Up make any present Class potent One or drugs that time in if we have drugs people be 1962. a were on weeks with no medical use. must safety. into play prescription. products, both must be effective had to be into abuse The just Drug to after in controlled. just refer they were divided we decided product came sold was killed. were effective as 1938 and a was it 1In liquid few that drugs, it was that required be it result, a they this One, 68 1912 distributed Schedule of was glycol only drugs time this difference was only prescription to a Amendment potenf was as As time but could occurred safe. the can that country require Humphrey most the the fortf it quinine sulfanilamide diethylene to at In dispensed It that act When capsule. in to drugs as didn’t a fact restrictions. in be amended Up and well company before over-the-counter as of this occurred. that Durham change big thing. manufacturing, certain said sort fashion. market commerce. in so labeling or the adulterated could tablet interstate Then one from troops, sulfanilamide Drug shown that disaster there largely was certain sulfanilamide discovered there American instituted to resulted it, or five are it safe; At not. classes. highly Schedule Two are highly potent drugs These two under particular a lower types Four established drugs for a use. with lower For most recent development would they the develop would evidence of million drug. If thirds the it discover and its of serious, environment, and compounds the seen generic substance and for could abuse of takes ten patents companies can seen this companies or drug years drug to when the they ever gets on today’s produce what is known competition to the 69 to of purchase the FDA control. a as a new market. the as generic "controlled and We early have trademarked an to two- good it relaxation of first a 1989 $125 develop lost year life seen from have the million, have costs the company $50 for we it a in it the with that actually submit if they during the are fact in these have then twelve the is $40 that Today before life have are deals that Today the you these be maybe it. activity, some of to well Five place to to that. is items. used copy there use. and Schedule taken rights Three Four and use. prescribed abuse Schedule costing however, results 1990 It drug, one sell has or established potential that patent We substance." abuse company has well in medical Schedule hypnotics. exclusive the sold In and drugs. new No $135 More a patent. be over-the-counter new get only potential to change of established example, lowest characteristically The with can abuse related the abuse circumstances. is barbiturates drugs of potential Schedule of example of in their on generic been have recently of a matter it teaching the medical it was used, when used, was brought about this_effect. we spend the what act influence of result that refer quite common their own the of image the of mechanism what chemical altering body drugs how learning is is drugs that structure was little action of how the and the which by bodily particular Very was it drug, a advantages others. to on--that what Durham they- changes are induced chemistry and neuronal as by before that time to can the I pharmacist take for my 70 fér people rather ailment? with than Was it ailments to 1951. in prescription only certain that Amendment Humphrey sold be directly say drug the to could and a knowing and drugs come of retc. activity, You because the and Today time most of cell the on drugs mechanism the about time that at generic applications compared as it of disadvantages known or teaching---initially in experiences my to back that industry. pharmaceutical Going there approval refused damage practices such me To product. from bought companies basis the on approved been not have they distribute to away taken permission product Administration Drug been their result, a numerous and have appropriately put they As it. and Food to compound the of developed under come and scrutiny permission instances numerous have get basis really that company to the on market the the product to the doctor a ES This was fairly careful for a had on 1938 How ES how he his that you have Today the for became see the to learn patient. of the the to go can so that he in with another and taking whether still Is the taking this programs if what is is these using a sees has problem. He the his pharmacy what can use today for of is very drug, that are occur. counseling that when for completely may The the retail the prescriptions patients’ see the the they today and towards effects towards his advised of levels thing of they drugs of of adverse directed common where therapeutic uses the his.computer to in he about geared in pharmacist dose record so-and-so generally pharmacy therapeutic are a patient until that compounding? everything the prescription he across in seeing, at keep to pharmacist the very a of the and is illegal item today and services It patient. pharmacist pharmacology anticipate pharmacist’s not very not an 6bjective about occur was be was the Consequently, likely it towards those you the virtually the actions to recommend It patient understanding knowledgeable time to skills directed drugs. that emphasis Since is At had illegal. purposes, curriculum pharmacist shelves. role principal therapeutic a example, prescription when do and responded. pharmacist, don’t the common comes customer the inquire physician is customer as that to he is medication. your perception country that 7 the a universal pharmacist aspect of sort of is an adjunct physician to oversee the dispensing of medication? That It is right. has been my experience completely understand the will often say, to That is _ The "Talk that often drug or your a its physician side does effects, not so he pharmacist." right. research you were Pocatello--were you the that summer? Is doing during learning the where you your teaching techniques at were learning the techniques in Minnesota the in research techniques? ES: That is these right. would carry it professor next, and you When had a but whole, example, it what of also had to left Idaho them followed I moves me on was at I would the at did impact tell would a great Idaho, your say, of Idaho I do to what my to findings me do a time. deal. little very where example to some University my how I quite report He research shall for accomplished I on, and on have research? impact, on my enough come me had Minnesota. result more lot while at done, being which starting were they teaching. a as developing It on Branch major learning Then experiment" Southern was was experiments. "chronic ES: I to not only associates impact the on on and my University down. U2 the my university as students. For that when students of Utah, a number a I of When do you you been ES: know in The at received present the University here idea joined for connection of Pharmacy Utah, a few college, solid and in of for Ph.D. the College four-year some long preparation Pharmacy a how your information I on with the was previous that of a to like to before I at 1947 College that. answer here of It if had school? in see Utah, Pharmacy medical initiated there would faculty College was but years and a the I was can not get that question. Did you have Goodman’s ES: Dr. Goodman pay actually that back funded by year was decided and school So was graduated as by a I I of staying come had hard back position College new but to back me, in Lou to could go back During of to the on me it I Utah. at of Utah. that even medical pharmacology. in the College Dr. Orr hired of Pharmacy that money? Yes. Were ES: you, Dr. Hiner, and Yes. 73 was for year mind in keep needed Idaho that University the I offer Pharmacy of and will which he appointment an you leave sabbatical. lecturer come stay, decided supported time did you funded to really that a start tried my to sabbatical the So back me a that money. to staff when taken also pay Goodman to you wanted had and immediately prior I soft one Dr. after department? remember to interest at the same time? THIS IS SESSION #10 WITH DR. EWART A. SWINYARD. THE DATE IS MARCH 23, 1990. THE INTERVIEW IS BEING CONDUCTED BY ROBERT MILLER IN HIS OFFICE AT RESEARCH PARK. (THIS IS PART OF THE EVERETT L. COOLEY ORAL HISTORY PROJECT.) RM: In today’s the subject College were at The of the Pharmacy of one more was enrolled that school first B.S. of was degree in The sciences, which pharmacy faculty, which Pharmacy the At It mean 11, which in was old physical to you the standard as were English, after to 74 health courses a or a faculty note women’s that gym building on of the with of course basic taught basic of this and the as a at chemistry, courses. 1, Pharmacy of for by education to no the to as class was years survey introduction an education not The five devoted a Pharmacy, time or Utah. there of not as freshman direction such the A since years, 1946 state the pharmacy 1947 the under usual in in of College actually the was over the four interesting located when efforts provide however, such that the education. require of University to to was courses history is was and background established the year; that not some organization culminated assigned year did enrollment 1947. college in the of actually first did it was double in same mathematics, However, formally part pharmacy present. botany, was Medicine. cover its professional that year to Association of in to 1947. school specifically College and the Pharmaceutical faculty in incorporated of going prior Pharmacy establishment Utah were University School regularly we pharmacy, pharmacy, three had arrived original swimming lower pool campus. Actually for a our the dean pharmacy and a room number and faculty laboratory, combination My official of Research. didn’t have taught the State. title any a 310 and we offices and the and was of Professor pharmacology pharmacology same pharmacy first class had for laboratory. Pharmacology the first I actually laboratory pharmacology a senior had and graduated we years, so at in Director course, two taught space laboratories- chemistry was courses sufficient three pharmaceutical pharmacognosy Since Our was I Idaho the spring of 1950. I had a very because at full that afternoon the of sections interest, Properties day of enabled This one, money on scientist for graduate but his program pharmacology might Drugs" which only initiate that time up in to Consequently, research. pharmacology. be working 75 My with we all were initial two or three in fact, I was a "Anticonvulsive for ran I initiated but many almost present Graduate me, an this of research the or greatest did I entitled project three large matter a full then have to and not to from As say facilities course. research, Experimental me our I teach and more necessary Goodman. Dr. with in was to exceptionally an laboratory same however, cooperation Since sometimes life. unusual sometimes had we academic not class. was it was and day and size enrollment, senior it laboratory in limited enjoyable time every classes four and from have had very early students they years. would in get a their degree College right of along with in example, one 1948 Faculty 1951, year to 1954, representative the I and from of the a member of this fromi1954 the students with Dean there: was also was serve named of on to to the Pharmacy a 1951 as served as chairman as and 1954 student in I Committee. and Perhaps came had to on 1948 Association. 1951 For serve organizing I was faculty College that from a in I committee terms Research committee that of Pharmaceutical University on to to Hiner appointment called named I in soon was number I developed unt:il$1:971° was what and organized that was When a I 1954-1968. American a member year the University. was I- served 1964-1967. significant most same I in Very general here and program program. the came sérved along the Pharmacology graduate for I the to role of group work committee, Council a our of undergraduate after 1957-1958, played So, the Council. Graduate Department committee graduation from the Medicine. involved the from the of function that committee? ES: The research There the of function among were College served money lands. the came The no of the the strings the money state was the Where University. to and of designated 76 the from by the law Medicine, of University. money come leasing to go to Utah. of University College general did Utah the the between drawn Pharmacy, of faculty entire stimulate to was Committee Research They from? of the The federal institutions of higher learning amount each institution and at that time all that came in meetings once a applications should How I be So on and half source. We consider the decide The enrollment, approximately would funds were there exactly, would be a on the but it of had faculty whether they committee? would representative campus. the got we research. based government where research remember There the that month members don’t was University from for received support funded. many ten. the to run about eight to from every college on | money was also available to fund all to the humanities and other colleges? ES: That is right. Were you able couldn’t, ES: I felt In those When was ES: It we in people and a $500 or you a $1,000 if you a large grant. year what pharmacy, in program project. worthwhile basic was graduate or use? every fund to the been have the in twelve individual made able did applications, initiated? would ten were mention that knew criteria days you student what the College of resolution that to ten handle I we was il I did twelve not going a had some not of have I 1950. them think graduate to graduate than later and school students. graduate that Pharmacy--not every virtually could year first the had one students more then so I four at career any one and as a time. result, extremely successful How you would I made the received a he from feel good graduate his about work to that individuals their selecting the the of I basis their can a that I had my were students? the I ever master’s that. 78 recommendations academic truthfully student, with throughout field. schools, interview. student, complete their on adhered the in about decision personal one go I performance, say had I there that degree and I is and only suggested move on. I CURRICULUM VITAE PERSONAL DATA Name: Ewart A. Swinyard Citizenship: U.S. Birthplace: Logan, Utah DEGREES BS5 1932 B.S. (Pharm), Utah State University (Zoology) Idaho State University (Pharmacy) 1936 M.S., 1941 Ph.D., 1947 D.Sc. D.Sc. University University (Hon), (Hon), 1983 1986 Utah State University of Minnesota (Pharmacology) of Utah (Pharmacology) University of Utah PROFESSIONAL EXPERIENCE A A mic A 11936-11939 8 39-1945 intmen Instructor of Pharmacy, College of Pharmacy, Idaho State College Assistant Professor of Pharmacy, College of Pharmacy, Idaho State College 1945-1946 University of Utah 1946-1947 Winthrop 1945-13947 Professor of Pharmacology, College of Pharmacy, Idaho State College 1945-1967 Lecturer in Pharmacology, 896k Professor of Pharmacology, College of Medicine, 1847-1977 Professor of Pharmacology, College of Pharmacy, R /0- 196 Dean, College of Pharmacy, University of Utah 1976-present Professor Emeritus of Pharmacology, College of Pharmacy Medicine, Research Research Fellow Fellow (Pharmacology) (Pfiarmacology) College of Medicine, University of Utah University of Utah University of Utah University of Utah and School of B. Visiting Professor S Si Teachers Seminar in Pharmacology, Purdue University 1SS3 Teachers Seminar in Pharmacology, University of Utah 1954 Teachers Seminar in Pharmaceutical Connecticut 11957 Teachers Seminar in Pharmacology, University of Washington 1960 Teachers Seminar in Pharmaceutical Education, 1963, 1970 Visiting Professor, Medical School, Education, University of University of Colorado University of Hawaii 1964 Teachers 1962-1966 Visiting Scientist, Utah Academy of Science 1962-1968 Visiting Scientist, American Association of Colleges of Pharmacy 1962-1968 Visiting Professor for Workshops on Alcoholism: Brigham Young University (2), Utah State University (2), Weber State College, Seminar in Pharmacology, University of Montana, University of Connecticut Halifax, and others Congress on Clinical Pharmacy Education, 11976 First International of Minnesota ST Teachers Seminar in Graduate Education and Research, Washington 978 Epilepsy International Symposium, Vancouver, University University of B.C., Workshop on "Principles of Screening Antiepileptics in Rodents" 1979 C. nsultan 19525119154 19I5 4= 19I55 1958-1978 IES6: 3419172 1964-1965 ilSi7:8=119187 1980-1981 American Society for Pharmacology and Experimental Therapeutics. Presented workshop for graduate students invited by the Society Vi Pfizer Company, Abbott New York City, New York Laboratories Deseret Pharmaceutical Co., Salt Lake City, Utah R.A. Gosselin Hoffman-LaRoche Deseret Medical, Salt Lake City, Utah Sandoz Labs, New Jersey ADMINISTRATIVE EXPERIENCE 1956-1960 National Formulary Advisory Panel, Subcommittee on Posology and Pharmacology 1958-1962 Advisory Board, Eastview Hospital, New York City 1962-1978 Director, University of Utah School on Alcoholism Dependencies 1965-197 1 S5 194 students, 1952-1977 inclusive) Chairman, Department of Biopharmaceutical Sciences, College of Pharmacy, 119701976 (14,562 and Other Drug University of Utah Dean, College of Pharmacy, University of Utah Board of Directors, Skaggs Companies, ! City Inc. (American Stores), Salt Lake EDITORIAL EXPERIENCE 1953-13960 Editorial Advisory Journal American Board, Journal of Pharmaceutical Sciences (formerly Pharmaceutical Association, Scientific Edition) 1953-1971 Editor, Annual Proceedings, District 8, American Association Pharmacy and National Association of Boards of Pharmacy 1960-1970 U.S. Pharmacopia Revision Committee 1965-1968 Editorial Board of the Journal of Pharmacology and Experimental Colleges of Therapeutics 1970113192 Editorial Board, 1977-1980 Consultant, A.M.A. Drug Evaluations, 3rd and 4th Editions 11979-1982 Editorial Board, Remington's Pharmaceutical Sciences Epilepsia MEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES 1953-54,62-64 Physiological Testing Committee of the American Pharmaceutical Association Chairman 11853- 1197 1954-1955 - 1855, 57, 59 Secretary and Treasurer, District 8, American Association of Colleges of Pharmacy and National Association of Boards of Pharmacy Chairman, Teachers of Biological Instruction, American Association Colleges of Pharmacy 1955-1956 Chairman, Teachers of Graduate Colleges of Pharmacy Instruction, American Association of of 1956-1987 Chairman, Council of Teachers, American Association of Colleges of Pharmacy 1957-1958 Chairman, Committee on Student Branches, and Vice-Chairman, Delegates, American Pharmaceutical Association 1958-1970 Utah State Board on Alcoholism 1958-1960 Executive Committee, American Association of Colleges of Pharmacy 1960-1961 Chairman, Utah State Board of Alcohol and Drugs 1961-1964 Research Achievement Association 1962-1964 Chairman, Committee on Graduate Programs, American Association of Colleges of Pharmacy 1968-1669 Chairman, Section on Biochemistry and Pharmacy, Academy of Pharmaceutical Sciences 1970-13880 Utah State Board on Drugs and Alcohol 1971-1974 NIH Epilepsy Advisory Committee, Drugs 7211975 NIH Epilepsy Advisory Committee 1973-1974 Chairman, Council of Deans, American Association of Colleges of Pharmacy 1978-present Member Awards Executive Committee Committee, House of Pharmaceutical American on Anticonvulsant Subcommittee University of Utah, and Board of Trustees, School on Alcoholism and Other Drug Dependencies RESEARCH FUNDING 1947-1974 Experimental Program Properties of Anticonvulsant Drugs, Senior Scientist, Project Anticonvulsant Properties of Experimental Pharmaceutical Industries 1965-1986 Research Director. 1969-1976 Pharmacology Training of Interest to Dentistry, $266,963 grant Director. Fellowship Funds, Hoffman-LaRoche $108,000 grant Medical, 971 -1'918/6 Personal Research, Deseret 1970-1976 Personal Research, Baxter Travenol Inc. Numerous Drugs. 1947-1965 Foundation, NIDR, Program Program $96,100 Laboratories. $6,000 grant G2 2P21 19728 975 Emerging Roles of the Pharmacist, NIH and IRMP, $29,503 grant Director. Toxicology of Toxic Substances Having Contact With Blood, NIH, CoInvestigator. $267,000 contract 1973-1975 Minority grant 1975-present Pharmacological Assistance, Pfeiffer Foundation, Evaluation contract. (1981-1983), $194,019 Personal 4/15/89), 5/16/89 Research, Program of Anticonvulsant (11/1/83 Drugs, - NIH, 4/15/84), $78,789 (extension, - 5/15/94). Gensia Director. Pharmaceutical. $16,400 Principal $1,650,582 (1975-1980), $1,455,411 Investigator. (4/16/84 $5,905,853, 1991-present Program $3,574,309 4/16/89 - 5/15/89), $9526 HONORS AND AWARDS A. Scholastic 1960 Rennebohn Utah 1§26 Lecturer, Pharmaceutical University of Wisconsin Association (Honorary Life Member) Invited Participant, International Conference on Psychophysiology, Neuropharmacology and Biochemistry of Audiogenic Seizures, Paris, France 1963 George Beecher Kaufmann Lecturer, Ohio State University 1965 Research Achievement Award in Pharmacodynamics, American Pharmaceutical Association Foundation 1966 Twice Honored as an outstanding teacher; Utonian Award and Associated Students of the University of Utah Lecture, Southwestern RSI67 Delivered 1968-1969 Distinguished 119618 Sigma Xi Distinguished 16875 Outstanding Alumnus Award, Idaho State University 976 Roche Annual Hicks Research Laboratories Memorial Professor, University University of Utah Faculty Lecturer, University of Utah Distinguished Faculty Award 1927 American Medical Society on Alcoholism Award and Medal for Distinguished Research and Education on Alcoholism [ESVaN Delivered Andrew G. DeMez 1981-1982 Honorary President, American Association of Colleges of Pharmacy 1982 Distinguished Service Award, Utah Academy of Sciences Memorial Lecture, University of Maryland Epilepsy Award: for Outstanding Contributions to the Pharmacologic Development of Antiepileptic Drugs. Selected by American Society for Pharmacology and Experimental Therapeutics. International Against Epilepsy 1983 Certificate of Appreciation: League Protection of the Health of the Public, National Association of Boards of Pharmacy 1984 Outstanding Achievement Award, Univ. of Minnesota. School Convocation, June 1. 1987 Professional Achievement Award, 1988 Outstanding Contributions to the Field, Utah Association of Alcohol and Drug Program Honorary Chairman, Association. 1990 Distinguished Basic Neuroscientist, Family Medical Foundation ISl Lifetime Achievement Award, Alumni Board of Trustees, Who's Who Who's Who Who's Who in the West in America in American Education American Men of Science American Men and Women American American Pharmaceutical Epilepsy Society - Milken University of Utah College of Pharmacy Recognition in the World University Providers 1989 Who's Who Idaho State Awarded at Medical of Science Leaders in Education, 5th Edition Personalities of the West and Midwest Outstanding Educators in America International Who's Who of Contemporary Achievement UNIVERSITY COMMITTEES 1948-1954 Graduation Committee 57-59, 1948-51, 1964-67 Faculty Council Chairman - 1958-59 1195 1-11:9241 Research Committee Chairman - 1954-1971 1954-1968 Graduate Council 1957-1958 Executive Committee, Faculty Council 1952-1963 Curriculum Evaluation Committee 1062-1971 Chairman, Planning Committee on Junior Science Symposium 1964 1964-1969 1967-1971 1968-1969 1968-1970 1967-1971 1967-1978 1968-1969 1968-1970 1970-1976 1973-1976 1972-1976 1979-1980 1979-1985 Presidential Search Promotions Advisory Committee Institutional Funds Committee Chairman, Development Advisory Committee Sabbatical Leave Committee Research Policy Committee Research on Human Subjects Academic Policy Committee for Development Tenure Advisory Committee Council of Academic Deans President's Administrative Health Sciences Council Council Committee on Future of the University Laboratory Animal Care Committee Chairman 1983 Committee - 1982-85 Future of the Institute of Bioengineering AFFILIATIONS Phi Kappa Phi Sigma Xi, President, 1961-1962 American Epilepsy Society American Society for Pharmacology American Pharmaceutical American College of Apothecaries and Association Experimental Therapeutics (Life Member) (Faculty Fellow) Phi Delta Chi Utah Academy of Science, Arts and Letters Rho Chi New York Academy of Sciences Western Pharmacology Society American College of Neuropsychopharmacology American Board of Diplomats in Pharmacy Epilepsy Foundation of America Epilepsy Association of Utah SCIENTIFIC AND PROFESSIONAL PUBLICATIONS Author or co-author of over 600 publications. manuscripts including 210 scientific and 140 confidential scientific reports, and 214 chapters in books. 88 professional Contributing author to the Pharmacoloqgical Basis of Therapeutics (5 editions), edited by Drs. Goodman and Gilman, and contributing author and member Editorial Board of Remington's Pharmaceutical Sciences (8 editions). PUBLICATIONS Ewart Swinyard, effects tions E.A., of in Hirschfelder, repeated the A. Swinyard, A.D., subcurative rat. J. and doses Pharmacol. Ph.D. Wright, of H.N. Mapharsen & Exper. Ther., Fed. Toman, Clin. Res., J.E.P. shock and seizures. Swinyard, Proc. Swinyard, E.A., hydration on 54, 2:100-101, Am. Toman, T. equiperdum infec- 1942. Laboratory technics antiepileptic drugs. E.A. Some Clin. J.E.P., and properties Res., experimental 2:98-99, Goodman, electroshock of L.S. electro- 1945. The convulsions. effects J. of cellular Neurophysiol. 9:47- 1946. Goodman, L.S., Swinyard, E.A., and Toman, J.E.P. Further studies on anticonvulsant properties of Tridione (3,5,5, trimethyloxazoladine, 2,4,dione). Federation Proc., 5:179, 1946. Toman, J.E.P., Swinyard, E.A., and electroshock seizures. Federation Goodman, L.S. Proc., 5:105, Some 1946. properties of maximal Studies on the anticonvulProc., 5:180, 1946. Toman, Observations J.E.P., Toman, sive Goodman, excitatory J.E.P. and 52105, and L.S., effects and Swinyard, of Metrazol. Swinyard, E.A. Federation A comparison to response non-convulsive E.A. cortical of Proc., time on the 5:208, 1946. relations in E.A., Toman, J.E.P., and electrolyte 5205, 1946. shifts on and Goodman, experimental The L.S. Federation convulsions. Proc., 12. Toman, J.E.P., and Neurophysiol., L.S., Swinyard, their and E.A., by alteration 9:231-239, Swinyard, Goodman, anticonvulsant drugs Goodman, L.S. Toman, ties of Tridione. 1:213-228, 1946. maximal other agents. J. 1946. E.A., and Toman, A comparison J.E.P. effects of 1 (+) glutamic acid and other agents on A.M.A. Arch. Neurol. & Psychiat., 56:20-29, 1946. 14. and potency of Properties L.S. water body of effects Laboratory assay of anticonvulsant Swinyard, E.A. and Goodman, L.S. Federation Proc., 5:205-206, 1946. of some hydantoinates. Goodman, Proc., 1946. Swinyard, seizures convul- Federation stimulation. 1 3% the Goodman, L.S., Swinyard, E.A., and Toman, J.E.P. sant properties of diphenylhydantoin. Federation central 10. for Proc. 1945. Fed. experimental on therapeutic 75:367-374, Goodman, L.S., Swinyafd, E.A., and Toman, J.E.P. the identification and evaluation of potentially Am. The J.E.P., Laboratory and Swinyard, and clinical E.A. experimental The of seizures. anticonvulsant investigations. Am. ?he J. proper- Med., 10 15. Goodman, L.S., Swinyard, the evaluation 43:820, 1946. of E.A., potentially and Toman, J.E.P. antiepileptic Laboratory drugs. Rocky technics Mountain for M.J., 16. Swinyard, E.A. and Goodman, L.S. nics for predicting antiepileptic Brae., 63376, "1947: 17. Toman, J.E.P., Swinyard, E.A., Merkin M., and Goodman, L.S. Studies on the physiology and therapy of convulsive disorders. II. Some properties of experimental convulsions. J. Neuropath. & Exper. Neurol., 7:35-46, 1948. 18. Swinyard, on E.A. and properties of Toman, Value of laboratory anticonvulsant techpotency and specificity. Federation J.E.P. convulsive Effects seizures 1948. in of alterations rats. in Federation body temperature RiRO G 25818 19. Goodman, L.S., Swinyard, E.A., and Toman, J.E.P. Anticonvulsant properties of 5-5 phenyl thienyl hydantoin in comparison with Dilantin and Mesantoin. Proc. Soc. Exper. Biol. & Med., 68:584-587, 1948. : 20. Swinyard, E.A. on properties 1948. and Toman, J.E.P. of convulsive Effects seizures in of alterations rats. Am. g1, Swinyard, E.A. drugs. J. Am. 22. Goodman, L.S., Toman, J.E.P., and Swinyard, E.A. mechanism of action and methods of assay. Arch. 162, 3. J. in body Physiol., 154:207-210, Laboratory assay of clinically effective antiepileptic Pharm. A. (Scient. Ed.), 38:201-204, 1949. 1949. Anticonvulsant drugs: int. Pharmacodyn., 78:144- Swinyard, E.A. The effect of extracellular electrolyte depletion on electrolyte patterns and the threshold for convulsive seizures. Am. Physiol., 156:163-169, 1949. 24. Swinyard, E.A. and Toman, some phenylhydantoins and Broc s 83350 11949 25 Swinyard, E.A. and Toman, J.E.P. A comparison of Anticonvulsant some phenylhydantoins and their corresponding phenylacetylureas. col. & Exper. Ther., 100:151-157, 1950. 26. Swinyard, E.A., of properties 59197 Z7 Jolley, J.E.P. Comparative their corresponding J.M., isomers optical Orr, of J.E., and anticonvulsant potencies of‘ phenylacetylureas. Federation Goodman, and Nirvanol brain J. L.S. Mesantoin. actions of J. Pharma- Anticqnvu]sant Federation Proc., °1950. Swinyard, E.A., ties of Benadryl 24281950 28. temperature Swinyard, E.A., Jolley, and J.M., and Pyribenzamine. Weaver, L.C., liver injury on anticonvulsant BRocS 0/ 339519517 and Goodman, L.S. The Proc. Soc. Exper. Goodman, L.S. activity anticonvulsant Effect Biol. & Med., proper- 75:239- of nephrectomy and of diphenylhydantoin. Federation 11 29. Swinyard, two new E.A., Bliss, E.L., spiro-cyclopentane and Goodman, barbituric acids. 1032364, " 1951 . 30. Anticonvulsant J. Pharmacol. properties & Exper. & Exper. Pharmacol. 104:309, Ther., 1952. Educ., 16:375-393, 1952. 3a Swinyard, E.A. Graduate instruction in pharmacology - Qualifications staff and students. Proceedings of Teachers Seminar on Pharmacclogy. Found. Pharm. Educ., 1951. Am. J. Pharm. Educ., 16:244-246, 1952. 33. Swinyard, E.A. Laboratory exercises in pharmacology University Press, University of Utah, 1951. 34. Brown, W.C., drugs 36. 37. in Weaver, Goodman, mice and L.C., L.S., rats. Swinyard, and Swinyard, Federation E.A., E.A. Proc., Woodbury, and students. of antiepileptic 1952. Goodman, L.S. Potency Swinyard, EJAT; ‘Briney, Olpin, H., and Goodman, R.E., L.S. K., on the anticonvulsant of activity Swinyard, E.A., and nephrectomy Pharmacol. Buchanan, G.A., Burnett, D.A., Forsyth, Effects of liver injury and nephrectomy trimethadione. Federation & Exper. Ther., 105:365-370, Weaver, and Swinyard, nephrectomy Exper. Biol. Swinyard, E.A., assay W.C., on the & Med., epileptic drugs SS0RIg52: Brown, E.A., and 80:744-746, Brown, in mice Schiffman, Goodman, anticonvulsant W.C., and and rats. D.0., of antiepileptic drugs threshold test. electroshock 11:394, 1952. 1952. 39. L.C., Proc., Schiffman, D.0., and Goodman, L.S. Effects of liver injury on the anticonvulsant activity of oxazolidine-2, 4-diones. Swinyard, C.A., Chu, C.H.U., Swinyard, E.A., C. The effect of nitrofuran on electroshock At MAnA Ea Rees 1293 $1952% J. The L.S. of activity of effects phenacemide. liver injury Proc. Soc. 1952. J. Comparative L.S. Goodman, Swinyard, by Ripstein, C.R., and Friedgood, seizure threshold in the albino Pharmacol. and E.A., Goodman, seizure "psychomotor" Pharmacol. & Exper. & Exper. test Ther., assay Ther., L.S. and of anti- 106:319'Cqmparative minimal 107:273-283, ig567 42. of on 38. 41. pharmacy Comparison 11:327, L.A., for of Am. antiepileptic drug combinations: Phenobarbital and diphenylhydantoin maximal electroshock seizures. Federation Proc., 11:401, 1952. J. 40. Ther., Swinyard, E.A. Undergraduate pharmacology - Laboratory, proceedings of teachers seminar on pharmacology, Am. Found. Pharm. Educ., 1951. Am. J. Pharm. 35. of Swinyard, E.A., Weaver, L.C., and Goodman, L.S. Effect of nephrectomy and liver injury on the anticonvulsant activity of clinically useful hydantoins. J. ‘3L L.S. Swinyard, E.A., Schiffman, D.0., Brown, W.C., Grewal, M.S., Arch. int. Unsaturated carbinols as anticonvulsants. L.S. 94:81-92, 1953. and Goodman, Pharmacodyn., 12 43. Weaver, L.C., Swinyard, E.A., and Goodman, L.S. drug combinations vs. Metrazol seizures in mice: other antiepileptics. Federation Proc., 12:379, 44, Swinyard, E.A., sants analeptics and rats. Tedeschi, Federation on D.H., and recovery Proc., Goodman, time 12:370-371, for Potency of anticonvulsant Dilantin combined with 1953. L.S. Effects maximal of anticonvul- electroshock 1953. seizures in 45. Brown, W.C., Goodman, Mysoline. Federation 46. Goodman, L.S., Grewal, M.S., Brown, W.C., and Swinyard, E.A. Comparison maximal seizures evoked by pentylenetetrazol (Metrazol) and electroshock mice, and their modification by anticonvulsants. J. Pharmacol. & Exper. Ther., 108:168-176, 1953. 47. Goodman, L.S., Swinyard, Anticonvulsant (Mysoline), 1953. 48. 49, Swinyard, E.A., and nephrectomy of Ed.), The of Jd. Educ., use Swinyard, E.A. Character logical sciences. Am. J. Bl Swinyard, 52, Weaver, E.A., Grewal, Pharmacol. audio-visual M.S., and & Exper. Smith, D.L., Swinyard, E.A., Bliss, Ther., of of in E.L. 108:428-436, of liver damage phenobarbital. 1954. aids in teaching pharmacology. Am. 1953. of research at the doctorate level Pharm. Educ., 18:260-267, 1954. antiepileptics. L.C., J. 43:114-116, 17:444-448, 50. useful W.C., properties 5-phenyl-5-ethyl-hexahydropyrimidine-4,6-dione antiepileptic. YAS(Sci. E.A. cally Brown, Anticonvulsant Tedeschi, D.H., and Goodman, L.S. Effects on anticonvulsant activity of Mysoline and Swinyard, Pharm. E.A., properties a new JERAmS S Pharm- L.S., and Swinyard, E.A. Proc., 12:305, 1953. and Goodman, J. Am. and Pharm. Goodman, L.S. A. L.S. Analgesic (Sci. the effects Ed.), Potency in bio- of clini- 43:212-214, of 1954, anticonvulsant drug combinations as determined by the maximal electroshock seizure pattern test in rats: mephobarbital combined with diphenylhydantoin sodium and phenobarbital sodium combined with phethenylate sodjum. J. Pharmacol. & Expers 38 ‘Ther.s Goodman, vulsant 2599). 54. L.S., 110:52, 1954, Swinyard, E.A., Brown, W.C., and Schiffman, D.0. properties of 5,5-diphenyl-tetrahydroglyoxaline-4-one J. Pharmacol. & Exper. Ther., 110:403-410, 1954. Swinyard, E.A., Madsen, J.E., and Goodman, L.S. The effect Anticon- (SKF of No. diethyl- aminoethyldiphenylpropylacetate (SKF No. 525A) on the anticonvulsant properties of some antiepileptic drugs. J. Pharmacol. & Exper. Ther., 111:54-63, 1954. 35, Grewal, between M.S., Swinyard, E.A., Jensen, H.V., and Goodman, anticonvulsant activity and plasma concentration Federation Proc., 13:361, 1954. L.S. Corre1atjon of sodium bromide. 56. Grewal, between J. 52, M.S., Swinyard, E.A., Jensen, H.V., and Goodman, anticonvulsant activity and plasma concentration Pharmacol. Swinyard, E.A., natremia tetrazol 58. Schiffman, Proc., of 14:384-385, -Weaver, phenobarbital. L.C., Pharmacol. Swinyard, Swinyard, drug & Exper. E.A., extracellular and Goodman, L.S. Goodman, fate and The effects of hypo- to pentylene14:389-390, 1955. L.S. Nephrectomy and excretion of drugs in liver rats. 1955. Federation E.A., Ther., sodium 14:390-391, L.A., and 113:359-370, D.0., and concentration and L.S. Studies diphenylhydantoin. on J. 1955. Goodman, on 1955. Goodman, phenobarbital (Metrazol)-induced 114:160-166, Proc., Woodbury, combinations: Schiffman, tylenetetrazol 62. D.0., 1954. Tedeschi, D.H., Swinyard, E.A., and Goodman, L.S. Effects of variation in stimulus intensity on seizure pattern, recovery time, and anticonvulsant anticonvulsant 61. 112:109-115, Schiffman, D.0., Swinyard, E.A., and injury as procedures for determining potency 60. Ther., and hypernatremia on the susceptibility of mice (Metrazol)-induced seizures. Federation Proc., Federation 59. & Exper. L.S. Correlation of sodjum bromide. the L.S. Effect susceptibility seizures. J. of variations of mice Pharmacol. to in pen- & Exper. Ther., 1955. Tedeschi, D.H. and Swinyard, students in graduate work in E.A. A program for stimulating qualified pharmacology. Am. J. Pharm. Educ., 19:90-95, 1955 63. Schiffman, D.0., Swinyard, E.A., and Goodman, L.S. Effect of and nephrectomy on the convulsant potency of pentylenetetrazol Broc Sac. Exper. Biolls & Med.:;190:124-127, 1955 64. 65. and anticonvulsant 81131551956, & Exper. potency Swinyard, E.A. Assist. Remington's Practice of Mack Publishing in mice. J. Pharmacol. Ed. Sec. on Pharmacology Pharmacy, 11th Edition. Co., Easton, Pa., Ther., 116:107- and Therapeutics. E.F. Cook and E.W. ) Martin 1956. Allmark, M.G., Anderson, R.C., Haley, T.J., Holck, H.G.0., Harrisson, A JEHCE. & Nelson, waW..,; .Swoap, 0.F., Weaver, L.C., and Swinyard, E.A. Tedeschi, normal Biol. 68. (Metrazol). Effects of variations in pattern, recovery time, the history of 2A05,341956. 67. damage Tedeschi, D.H., Swinyard, E.A., and Goodman, L.S. stimulus intensity on maximal electroshock seizure (Eds.?. 66. liver D.H., and committee Swinyard, physiological E.A., diphenylhydantoin & Med., 93:379-382, Swinyard; E.A., Chin, L., properties of 1-glutamine Exper..Biol. on & Med.., and Drug testing. Goodman, Postictal L.S. (Dilantin)-treated mice. 24:200- Standards, Proc. recovery Soc. in Exper. 1956. Cole, F.R., and Goodman, and 1-asparagine in mice 94:12-15, 1957. Anticonvulsant L.S. Proc. Soc. and rats. 14 69. Swinyard, chronic C.A., ethanol of mice. 70. 71. Workman, R.L., Jr., administration Anat. Rec., on and the weight 127:375-376, Laffan, R.A., Chin, L. and in Exper. Swinyard, E.A., Weaver, 77. by E.A. and Goodman, E.A., Diphenylhydantoin A. (Sci. Ed.), Tedeschi, D:H. and recovery time from Ther., and Stimulus withdrawal of Goodman, 47:645-648, gland in intensity rats. mice. maximal Arch. int. hyperexcitability phenaglycodol. Proc. Soc. L.S. with other 1958. : Anticonvulsant antiepileptics. drug J. combi- Am. of Swinyard, E.A. Effects of anticonvulsant drugs on tonic-clonic seizures in mice and rats. J. Pharmacol. 124:161-164, Swinyard, E.A., cological properties Swinyard, 1958. Wolf, H.H., Fink, G.B., of thioridazine and Goodman, hydrochloride L.S. Some (Mellaril). neuropharma- J. Pharma- and Fink, G.B. Maximal by Fink, G.B. and Swinyard, E.A. electroshock seizures in mice Ther., 127:318-324, audiogenic psychopharmacologic and electroshock agents. seizures Federation Modification of maximal audiogenic and J. Pharmacol. by psychopharmacologic drugs. 1959. psychopharmacologic qrugs on J. Am. Pharm. A. (Sci. Eam) Effects of Fink, G.B. and Swinyard, E.A. experimentally-induced seizures in mice. 1960. Miyahara, Swinyard, E.A., fluencing amphetamine J.T., toxicity Wolf, H.H., in aggregated and Clark, mice. Factors L.D. Federation Proc., in- 19:23, 1960. 82. & Ther.5 1265 312-317 , 1959 E.A. 49i:510-513," 81. and adrenal Chin, L. and Swinyard, E.A. Phenaglycodol seizure threshold in meprobamateand phenaglycodol-treated mice. J. Am. Pharm. A. (Sci. ED.), 48:6-8, 1959. Exper. 80. of 1958. combined in mice and their alteration Proc., 18:449, 1959. 7S and administration 97:251-254, Swinyard, L.S. of anticonvulsants Tolerance chronic & Med., calPNEFExper.” 78. thymus effect Workman, R.L., Jr:, Swinyard, E.A., Rigby, 0.F., and Swinyard, C.A. Correlation between anticonvulsant activity and plasma concentration ethanol. J. Am. Pharm. A. (Sci. Ed.), 47:769-772, 1958. Exper. 76. mice L.C., Pharma. 75, Swinyard, Biol. nations: 74. of the The Swinyard, E.A., Chin, L., and Fingl, E. Withdrawal hyperexcitability following chronic administration of meprobamate (Equanil, Miltown) to Science, 125:739-741, 1957. induced [318 E.A. 1957. electroshock seizures, and potency Pharmacodyn., 111:60-69, 1957. 72. Swinyard, Gesler, R.M., Lints, C.E., and stituted 2-thiohydantoins with J. Tox. & Applied properties. Swinyard, E.A. Pharmacology of some particular reference to anticonvulsant Pharmacology, 3:107-121, 1961. sub- & 15 Swinyard, 83. E.A., Clark, L.D., Miyahara, mechanism of amphetamine toxicity Exper-tTher., 132:97-102, 1961. 84. Wolf, 85. Swinyard, E.A. Assist. Remington's Practice of some H.H., N-substituted (Eds.). 86. = Swinyard, Mack Swinyard, and their E.A., and J. and Wolf, aggregated Goodman, hydantoins. L.S. Pharm. Co., Easton, J. Fink, G.B., and pharmacologic 8s. Swinyard, restraint Ther., 89. Wolf, drugs. E.A. J. Sciences, of Swinyard, E.A., Miyahara, on the anticonvulsant 465, 1963. 91. and Clark, J.T., g2 < L.D. Castellion, E.A., and neurophysiological 998 Castellion, audiogenic 94, and norepinephrine Pharmacol. 95. - Castellion, thyroid 96. & Exper. A.W. Ther., and Proc., E.A. Orientation 1964. of and of L.S. Effects J. Pharm. of chlorination Sci., 52:463effects The L.S. in threshold seizure and Ther., and audiogenic1963. 140:375-384, of reproducibility Pharmacologist, mice. central of . Sqme L.S. Goodman, characteristics 1963. 5:238, L.S. Effect Qf epinephrine nervous system in Goodman, and. J. mice. 1964. Audiogenic 23:198, effects of Goodman, and & Exper. in E.A. the differential of conditioned avoidance Psychopharmacologia, 3:438- Maturation E.A. 144:52-59, Swinyard, Fed. 28:763-768, L.S. Effect of brief J. Pharmacol. & Exper. The G.B., Fink, seizures F.C.B., activity. Swinyard, psycho- 1963. Pharmacol. excitability on and 1962. pentylenetetrazol on A.W., J. electroshock Boson, L.D., 4:343-353, Swinyard, and A.W. E.A., Swinyard, anticonvulsant phenobarbital. neuropharmacological mice. seizure-susceptible Goodman, Clark, stress Psychopharmacologia, Swinyard, of J.T., of experimentally-induced mice. and activity Miyahara, E.A.; Swinyard, in mice on 1962. Swinyard, E.A., Martin of Audiogenic 112:405-427, 1963. 51:548-551, chlorpromazine and pentobarbital on two forms behavior in Peromyscus maniculatus gracilis. 448, 1962. 90. of 1962. and Therapeutics, E.R. Cook and E.W. E.A., Radhakrishnan, N., and Goodman, on the convulsive threshold of mice. H.H., properties 1961. A comparison Pharm. the & physiological properties of audiogenic seizures by drugs. Proceedings International Conference Swinyard, 138:337-342, on Pharmacol. 51:74-76, Psychophysiology, Neuropharmacology, and Biochemistry Seizures, Paris, France, International Colloquium No. 87. Studies Anticonvulsant Sci., PA, H.H. mice. Ed. Sec. on Pharmacology Pharmacy, 12th Edition. Publishing E.A. Some alteration in J.T., seizure susceptibility 1964. graduate student. Am. J. Pharm. ; Ed., and 16 97. - Castellion, A.W., Swinyard, E.A., and Goodman, L.S. Effect of maturation on the development and reproducibility of audiogenic- and electroshock-seizures in mice. Exper. Neurol., 13:206-217, 1965. 9. Swinyard, E.A. Chapters), 39, and 13th Harvey, Edition. Swinyard, E.A. Edition. 1965. Goodman, S.C. Remington's Mack Publishing Pharmacological L.S. and Basis Gilman, ; Company, of A. Pharmaceutical Easton, Therapeutics (Eds.). Sciences (3 PA, (28 1965. Chapters), Macmillan 3rd Company, New York, 100. Swinyard, E.A. and Castellion, benzodiazepines, J. Pharmacol. A. W. Anticonvulsant properties of some & Exper. Ther., 151:369-375, 1966. 101. Kemp, Diphenylhydantoin J.W. and metabolism Swinyard, by liver E.A. microsomes in mice and inhibition rats. of hexobarbital Fed. Proc.r 2743508 102. Swinyard, E.A. Laboratory evaluation of antiepileptic laboratory methods. Epilepsia, 10:107-119, 1969. drugs: Review 103. Swinyard, E.A. Chapters), 104. Swinyard, Edition, 1970. 105. 14th S.C. Remington's Mack PubTishing Pharmacological Goodman, L.S. and Basis Gilman, Pharmaceutical Company, of Therapeutics A., (Eds.). inflammation. Arthritis Kemp, J.W., Tannhauser, M., and hydantoin on hexobarbital sleep Swinyard, and 1971. E.A. Assay of antiepileptic drug PA, Macmillan E.A. rats: 108. Swinyard, cology of R.P. 109. New Woodbury, D.M. tribution and New York, 13:3, York, of 1970. The effect of diphenylArch. int. Pharmacodyn., activity in experimental International (Ed.). Pergamon Press, and Swinyard, excretion D.M., New York, E.A. (Chapter Penry, J.K., PharmaSchmidt, 1972. Diphenylhydantoin: 11, In: and pages and 113-123). Schmidt, R.P. Absorptjone In: dis- Antiepileptic (Eds.]. Raven Press, 1972. Swinyard, E.A. Electrically induced convulsions (Chapter 17, pages 458). In: Experimental Models of Epilepsy. Purpura, D.P., Penry, Tower, D., Woodbury, D.M., and Walter, R. (Eds.). Raven Press, New 1972~ New 1972. Raven Woodbury, 4th 6-Sulfanilaa new model E.A. and Goodman, L.S. Introduction (Chapter 1). Antiepileptic Drugs. Woodbury, D.M., Penry, J.K., (Eds.). Drugs. 110. York, 1970. Company, animals: Standard Tests (Section 19, Vol. 1, pages 47-65). Encyclopedia of Pharmacology and Therapeutics. Mercier, J. Press, of (29 (3 Chapters), Rheumatism, Swinyard, E.A. time in rats. Sciences Easton, Miller, M.L., Ward, J.R., Cole, B.C., and Swinyard, midoindazole induced arthritis and periarthritis in 192:204-212, 107. Harvey, Edition. E.A. experimental 106. and 11968 433J.K., York, 17 111. Giam, C.S., nervous Keener, system tetrazole. of the I.G., activity 1. Woodbury, D.M., of compounds Chemical Swinyard, structurally Bicyclohydantoins. American and Abstracts Society, Los E.A. related Central to pentylene- of the 167th National April 1974, MEDI Angeles, Meeting 077. 112. Swinyard, E.A. and Harvey, S.C. Remington's Pharmaceutical Sciences Chapters), 15th Edition. Mack Publishing Company, Easton, PA, 1975. 113. Swinyard, E.A. Edition, 1975. 114. Goodman, L.S. and Basis Gilman, of Therapeutics A., (Eds.). (3 Chapters), 5th Company, New Macmillan York, Swinyard, E.A., Woodhead, J.H., and Petersen, R.B. Nonspecific effect of bis(2-ethylhexyl) phthalate on hexobarbital sleep time. J. Pharm. SE ks 1976. 65:733-734, 5. Pharmacological (29 Knaus, E.E., Pasutto, F.M., Giam, C.S., Swinyard, E.A. Diels-alder cyclo- additions of N-substituted-1,2-dihydropyridines with 1,2,4-triazoline-3, 5-diones and maleimides. J. Heterocyclic Chem., 13:481-486, 1976. 116. Swinyard, pestles.. 117. Krall, R.L., leptic Drug 408, E.A. and Woodhead, J.H. Drug J. Pharm. Sci., 67:1758-1759, Penry, J.K., Kupferberg, Development: I. contamination 1978. H.J., Background and and 1978. of mortars Swinyard, program. Krall, R.L., Penry, J.K., White, Antiepileptic Drug Development: Epilepsia, 19:409-428, 1978. B.G., Kupferberg, H.J., II. Anticonvulsant drug 119. Shenoy, Influence and Swinyard, potassium-induced 120. release of Pharmacologist, 21:189, Swinyard, Principles E.A. E.A. 3H-GABA 121. 122. 123. 124, of selected chemicals on rat cerebral cortex vitro. in of screening antiepileptic in Epileptology: and Penry, J.K., drugs The Xth (Eds.). in E.A. rodents Epilepsy InterRaven Press, New 0. E.A. 1). In: J.K., and Antiepileptic Drugs: Mechanisms of Action. Glasser, Woodbury, D.M. (Eds.). Raven Press, New York, 1980. Swinyard, E.A. Edition. Goodman, Introduction: History Pharmacological and L.S. Basis of antiepileptic of Therapeutics‘(Z A., Gilman, the Macmillan (Eds.). drugs (Chapter G.H., Penry, Chapters), 6th Company, New 1980 E.A. Edition. Mack Swinyard, E.A., clobazam, 861100, Pharmaceutical Remington's Swinyard, of 19:393- and Swinyard, screening. Swinyard, ferks: Antiepi- 1979. (pages 303-399). In: Advances national Symposium. Wada, J.A. ork, from E.A. Epilepsia, 118. A.K. and PubTishing Shenoy, diazepam, 1980. Easton, Company, A.K., and Sciences PA, Kupferberg, phenobarbital and (16 Chapters), 16th 1980. H.d. valproate. Anticonvqlsant Federation profiles Proc., 18 125. Swinyard, drugs. E.A. and Degussa Kupferberg, Pharma H.J. Research The Report, early evaluation August, pp 1-36, of anticonvulsant 1980. 126. Shenoy, A.K., Swinyard, E.A., Kupferberg, H.J., and Yonekawa, W.D. Paradoxical effect of polyethylene glycol 400 (PEG) on brain excitability and anticonvulsant activity of selected drugs. Federation Proc., 39:1100, 1980. 127. Shenoy, A.K., Bakhit, C., Miyahara, Tryptophan hydroxylase and tyrosine seizure 128. susceptible brain. Pharmacologist, 22:184, Gibb, J.W. audiogenic 1980. Kupferberg, H.J., Swinyard, E.A., and Gladding, G. ADD program NINCDS: early pharmacological evaluation of new antiepileptic drugs. Acta. Neurol. Coleman, J.C., 1980. 63:5-6, 79, Suppl Scand., 129. mouse J.T., Swinyard, E.A., and hydroxylase activities in Shenoy, A.K., Swinyard, E.A., and Kupferberg, H.J. Analysis of the interaction between bicuculline (B), picrotoxin (P) or Metrazol (M) and phenobarbital (PB), diazepam (D) or valproate (V) in mice. Federation Broc., 130. 40:325, 1981. Shenoy, A.K., Bakhit, C., Swinyard, E.A., and Gibb, J.W. Choline acetyltransferase and glutamic acid decarboxylase activities in audiogenic seizure susceptible (Frings) mouse brain. Federation Proc., 40:271, 1981. 131.< Shenoy, A.K., Miyahara, J.T., and Swinyard, E.A. Influence audiogenic or electroshock seizures on the release brain in vitro. Proc. of the Western Pharmacology 132.- Bakhit, C., minergic mice. Shenoy, and A.K., Swinyard, serotonergic Pharmacologist, 133. Swinyard, E.A., 45:432, 1981. 134. Gladding, G.D., systems 23:133, E.A., and maximal of 3H-GABA from Soc., 24:89-91, Gibb, in audiogenic of J.W. seizure Altered mouse 1981. catechola- susceptible (Frings) 1981. Research: Some Kupferberg, H.J., do, and most don't. Am. Swinyard, development program (pp 13-18). Handbook Volume "Antiepileptic Drugs." Frey, H.H. E.A. J. Pharm. Educ., Antiepileptic drug of experimental pharmacology. and Janz, D. (Eds.). Springer, 1981. 135. Kupferberg, H.J., Swinyard, E.A., and Gladding, G.D. Early pharmacological evaluation of new antiepileptic Epileptology: Penry (Eds.). 136. Swinyard, Drugs, (Eds.). 137. E.A. 2nd The XII Epilepsy Raven Press, New Introduction Edition. Raven Press, New International Symposium. York, p.13-18, 1981. (Chapter Woodbury, York, D.M., 1, pages Penry, Raven Press, New York, 1-9). J.K., and In: Dams, Gram, and Antiepileptic Pippenger, C.E. 1982. Swinyard, E.A. and Woodhead, J.H. Experimental evaluation of anticonvulsants (Chapter 7, pages Woodbury, D.M., Penry, tic Drugs, 2nd Edition. (Eds.). ADD program of NINCDS: drugs. Advances in 1982. detection, quantitation and AntiepilepIn: 111-126). J.K., and Pippenger, C.E. 19 138. Swinyard, 46:88-89, E.A. 1982. 139. Swinyard, E.A. Research: Pharm. Educ., 46:192-193, Current 1982. problems 140. Bakhit, Swinyard, E.A., C., chemical Research: Shenoy, A.K., parameters seizures. Brain Is it cost in the brains Research, effective? and of mice 244:45-52, and Am. J. Pharm. a possible Gibb, (Frings) J.W. ' Educ., solution. Altered susceptible Am. J. neuro- to audiogenic 1982. 141. Shenoy, A.K., Miyahara, J.T., Swinyard, E.A., and Kupferberg, H.J. Comparative anticonvulsant activity and neurotoxicity of clobazam, diazepam, phenobarbital, and valproate in mice and rats. Epilepsia, 23:399-408, 1982. 142. Johnson, D.N. and Soc. Neuroscience 143. Chweh, 144, Pentylenetetrazol Chweh, A.Y., Swinyard, E.A., and Wolf, H.H. criminate between different types of benzodiazepine receptors. vulsant activity and Abst., 8:454, 1982. Chweh, 41:830-833, 1983. Swinyard, E.A., A.Y., Chweh, A.Y., muscimol- and mouse brain. 147. More, binding Swinyard, E.A., and Wolf, barbiturate-stimulated Soc. Neurosci. Abstr., Gladding, H., binding. anticon- between Soc. Neuroscience may J. and activity, disNeuro- Correlation H.J. Kupferberg, agent. displacing Epilepsia, of benzodiazepines. 1983. 24:668-677, 146. and anticonvulsant in [3H]flunitrazepam potencies antiepileptic Correlation receptor H.H., Wolf, neurotoxicity, minimal between benzodiazepine a potential H.H. Wolf, and E.A., Swinyard, A.Y., chemistry, 145. Swinyard, E.A. AHR-8559, Abst., 8:467, 1982. G.D., Cook, L., Effect H.H. of receptor [3H]flunitrazepam 9:403, 1983. Swinyard, E.A. Fifteenth Anticonvulsant Screening Data Reporting. Symposium, Washington, DC, September 26-30, p. 369, on pentylenetetrazol Automation Epilepsy 1983. binding in of International 148. Benzodiazepine inhibition of Chweh, A.Y., Swinyard, E.A., and Wolf, H.H. flunitrazepam receptor binding, adenosine uptake, and pentylenetetrazolCanadian J. Physiology and Pharmacology, 62:132induced seizures in mice. 135, 51984. 149, Chweh, pines: A.Y., a Lin, possible Y.B., and Swinyard, mechanism. Life E.A. Sci., Hypnotic of benzodiaze- action 34:1763-1768, 1984. 150. Effect of Ulloque, R.A., Chweh, A.Y., Swinyard, E.A., and Wolf, H.H. Soc. Neuroscience Abst., picrotoxinin on benzodiazepine receptor binding. 5618 1984 151. Correlation Chandler, L.J., Leslie, S.W., Chweh, A.Y., and Swinyard, E.A. of benzodiazepine hypnotic potency with inhibition of voltage-dependent calcium uptake into mouse Abstract, 10:420, 1984. whole brain synaptosomes. Soc. Neurosci. 20 152, Ater, S.B., Swinyard, E.A., Tolman, Effects of metabolic manipulation of valproic acid. Clinical Res., 183, 154. 25:551-555, 1984. Ater, Swinyard, sant 604, S.B., of SKF525A, activity 1984. Chweh, and A.Y., agonists E.A., J.A., on antiepileptic 32:54A, 1984, Tolman, the Life K.G., phenobarbital, neurotoxicity » Swinyard,‘E.A., on pines. 156. Madsen, Sciences, fasting of H.H. and and valproate Wolf, neurotoxicity Madsen, and in mice. (Eds.). Springer, H.J. E.A. Edition. Goodman, L.S. and Basis Gilman, Piredda, S.G., Woodhead, intensity on the profile J. of mide, Pharmacol. and valproate. J. (16 of Therapeutics A.G. 1985. York, The anticonvul- 25:599- Effect of GABA of benzodiaze- Handbook of experiFrey, H.H. and Janz, 1985. Pharmacological the F. 1985. Swinyard, (Eds.) (2 Therap., 17th Chapters), 7th Company, New Macmillan H. and Swinyard, E.A. The anticonvulsant activity of Exp. Chapters), effect of stimulus phenytoin, ethosuxi- 232:741-745, 1985. Chweh, A.Y., Swinyard, E.A. and Wolf, H.H. GABA modulation of benzodia;epine receptor binding in vitro does not predict the pharmacologic activity of all 1985. benzodiazepine receptor ligands. 161. Chweh, A.Y., Swinyard, E.A., and benzodiazepine receptor binding. 162. Chweh, A.Y., toxinin 1985. on Coleman, Ulloque, R.A., benzodiazepine J.C., Shenoy, Swinyard, receptor A.K., Swinyard, E.A. fication, and Chweh, involved A.Y., in Neuroscience and evaluation. Swinyard, the neurotoxicity Letters, A.Y. H.J. Wolf, and 57:279-282, Wolf, Letters, Swinyard, convulsants 44:2629-2633, H.H. 54:173-177, Effect Res., E.A. and drugs: of in picro- 10:871-877, An analysis of anticonvulsants. detection, quanti- 1985. Benzodiazepine antielectroshock 1985. H.H. Neurochem. Antiepileptic Proc., and and and chemical Fed. E.A. E.A. binding. Chweh, Kupferberg, Neuroscience Wolf, H.H. GABA: temperature dependence J. Neurochemistry, 45:240-243, 1985. the in vivo interactions between Life Sciences, 37:749-755, 1985. 165. properties Epilepsia, activity 158. 164, F. Matsuo, on Kupferberg, anticonvulsant 36:737-744, and carnitine Swinyard, E.A. Remington's Pharmaceutical Sciences Edition, Mack Publishing Company, Easton, PA, 1985. 163. Matsuo neurotoxic J.A., 157. 160. and Swinyard, E.A. Acetylurea derivatives (pp 601-610). mental pharmacology. Volume 74, Antiepileptic Drugs. D. 159, and Ater, S.B., Swinyard, E.A., Tolman, K.G., and Franklin, M.R. Anticonvulsant activity and neurotoxicity of piperonyl butoxide in mice. Epilepsia, effects 155. K.G., activity receptors of are phenytoin. not 21 166. Johnson, D.N., Kilpatrick, antiepileptic 167. Gladding, agent. G.D., Kupferberg, Lin-Mitchell, E. on brain content GABAa GABA receptor and Neuroscience Swinyard, Abstr. H.J., and E.A. AHR-11748, 11:1317, Swinyard, A potential 1985. E.A. Antiepileptic Drug Volume 74, Handbook of Experimental Pharmacology. Frey, H.H. and Janz, D. (Eds.). Springer, 1985. Development Program. Antiepileptic Drugs. 168. B.F., Chweh, A.Y., and agonist and the Swinyard, in vivo (THIP) n E.A. The interaction Mice. Soc. effect between of ethosuximide ethosuximide Neuroscience Abstracts, and 11:283, 1985. 169. Kupferberg, H.J. and Swinyard, of anticonvulsants. Fed. International Workshop on 170. 7L uptake 1986. into synaptosomes. Chweh, A.Y., mouse Chweh, brain Ulloque, R.A., binding 122:161-165, A.Y., Swinyard, and and E., Chweh, and Eur. Swinyard, J. Pharmacol., Ulloque, R.A., Chweh, at E.A. 126:129-134, Benzodiazepine seizures in inhibition mice. Eur. E.A., and A.Y., Wolf, action and H.H. of Involvement phenytoin. Swinyard, E.A. of J. a GABAergic Pharmacol. The effect A.Y., and Swinyard, E.A. The of Biochem. of ethosuximide GABA concenJ. Pharmacol. of effects agonists on the neurotoxicity and anticonvulsant activity J. Pharmacol. & Exp. Therap., 237:468-472, 1986. mice. GABA receptor barbiturates -— 175, Comparative aqtigonvu§1ant Swinyard, E.A. Sofia, D.R., and Kupferberg, HJ. activity and neurotoxicity of felbamate and four prototype antiepileptic Epilepsia, 27:27-34, 1986. drugs in mice and rats. 176. Chweh, A.Y., Ulloque, activity of diazepam: i Chweh, tal in 178. Swinyard, E.A. Woodhead, J.H., Franklin, M.R. Sofiia, DaR., and Kupferbgrg, Effect of chronic felbamate administration on anticonyulsaqt activity H.J. R.A., and Swinyard, A site of action. E.A. Drug Antipentylenetetrazol Dev. Res., 9:259-265, 1986. Hypnotic action of pentobarbiA.Y., Swinyard, E.A., and Wolf, H.H. Experimental Neurol. 97:70-76, 1987. mice : A possible mechanism. and hepatic 00,7 1987. of 1986. alone and in combination with GABA receptor agonists on brain tration, anticonvulsant activity, and neurotoxicity in mice. & Exp. Therap., 237:486-489, 1986. 174. evaluation and Swinyard, E.A. Correlation with voltage-dependent calcium caffeine-induced mechanism in the pharmacologic Behav., 24:1301-1304, 1986. Lin-Michell, detection Proc. 44:2629-2633, 1985. Also presented Flunarizine in Epilepsy, May 1985. L.J., Chweh, A.Y., of benzodiazepines Pharmacol., 173. Experimental Leslie, S.W., Chandler, of the hypnotic potency [3H]flunitrazepam 172. E.A. drug-metabolizing enzymes in mice and rats. Epilepsia 28:295- in 22 i19. Singh, N.A., Swinyard, E.A. and White, H.S. Effect of prototype anticonvulsants on Nmethyl-D-aspartate (NMDA)-induced seizures in mice, FASEB J. 2:A1068, 1988. 180. Singh, N.A., Swinyard, E.A. and White, H.S. Effect of prototype anticonvulsant agent s on Quisgualic acid (QA)-induced seizures in mice. Soc. Neurosci. 14:240, 1988. 181. White, H.S., Bender, A.S. and Swinyard, E.A. Effect of the selective N-methy|-D- aspartate receptor antagonist 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid on [3H]flunitraze-pam binding. Eur. J. Pharmacol. 147:149-151, 1988. 182. Swinyard, E.A., White, H.S. and Wolf, H.H. Mechanisms of anticonvulsant drugs. Atlas of Science: Pharmacology, 2:95-98, 1988. 183. White, H.S., Singh, N.A. and Swinyard, E.A. Effect of Ca®*-channel blockers on Nmethyl-D-aspartate (NMDA)- and quisqualic acid (QA)-induced seizures. Soc. Neurosci. 15:215, 1989. 184. Swinyard, E.A., Woodhead, J.H., White, H.S. and Franklin, M.R., IS/ Experimental selec- tion, quantification, and evaluation of anticonvulsants. In: Antiepileptic Drugs, Third Edition, edited by R. Levy, R. Mattson, B. Meldrum, J.K. Penry and F.E. Dreifuss, pp. 85-102, Raven Press, Ltd., New York, 1989. 185. Johnson, D.N., Taylor, C.R., Jr., Tomczuk, B.E, and Swinyard, E.A. AHR-12245: potential antiepileptic for the treatment of absence seizures. AES Proceedings, a Epilepsia 29(5):694, 1988. 186. Carchman, R.A., Gennings, C., Swinyard, E.A., and Carter, W.H., Jr. The use of response surface methodologies in understanding drug interactions. In: Antiepileptic Drug Interactions. W.H. Pitlick (Ed.). pp 245-259, Demos Publications, New York, New York, 187. Swinyard, 1989. E.A., Woodhead, J.H., and Wolf, H.H. predicting drug interactions. 261-275, 188. Demos Publications, In: The use of isobolograms in Antiepileptic Drug Interactions. New York, New York, W.H. Pitlick (Ed.). pp 1989. Palmer, G.C., Harris, E.W., Napier, J.J., Stagnitto, M.L., Garske, G.E., Griffith, R.C., and Swinyard, E.A. Status of PR934-423, a novel anticonvulsant targeted for generalized tonic/clonic seizures (*new designation is FPh 12924AA). In: Current and Future Trends in Anticonvulsant, Anxiety, and Stroke Therapy. M. Williams (Ed.). Alan R. Liss Inc., 1989. 189. Stagnitto, M.L., Palmer, G.C., Ordy, J.M., Griffith, R.C., Napier, J.S., Becker, C.W., Gentile, R.J., Garske, G.E., Frankenheim, J.M., Woodhead, J.H., White, H.S. and Swinyard, E.A. Preclinical profile of remacemide: a novel anticonvulsant effective against maximal electroshock seizures in mice. Epilepsy Res. 7:11-28, 1990. 190. Skeen, G., Woodhead, J., Wolf, H., Swinyard, E., Tietz, E. and White, S. of kindled seizures following electrical stimulation of the cornea. 16(1):307A (#138.1), 1990. Develqpment Soc. Neurosci. 23 131. Raines, A., Henderson, T.R., Swinyard, E.A., and Dretchen, K.L. Comparison of midazolam and diazepam by the intramuscular route for the control of seizures in a mouse model of status epilepticus. Epilepsia, 31(3):313-317, 1990. 192. Johnson, D.H., Osman, M.A., Cheng, L.K., and Swinyard, E.A. Pharmacodynamics and pharmacokinetics of AHR-11748, a new antiepileptic agent in rodents. Epilepsy Res., 5:185-191, 1990. 193. Swinyard, E.A. Remington's Pharmaceutical Sciences (15 Chapters), 18th Edition, Mack Publishg Company, Easton, PA, 1990. 194. Palmer, G.C., Stagnitto, M.L., Crdy, J.M., Griffith, R.C., Napier, J.J., Gentile, R.J., Woodhead, J.H., White, H.S. and Swinyard, E.A. Preclinical profile of sterecisomers of the anticonvulsant remacemide in mice. Epilepsy Res. 8:36-48, 1991. 195. Johnson, D.N., White, H.S., Swinyard, E.A., Albertson, T.E. and Kilpatrick, B.F. 12245: A potential anti-absence drug. Epilepsy Res. 8:64-70, 1991. 196. Garske, G.E., Palmer, G.C., Napier, J.J., Griffith, R.C., Freedman, AHR- L.R., Harris, E.W., Ray, R., McCreedy, S.A., Blosser, J.C., Woodhead, J.H., White, H.S. and Swinyard, E.A. Preclinical profile of anticonvulsant remacemide and its enantiomers in the rat. Epilepsy Res. 9:161-174, 1991. 197. Swinyard, E.A., White, H.S., Wolf, H.H. and Bondinell, W.E. Anticonvulsant profiles of the potent and orally active GABA uptake inhibitors SK&F 89976-A and SK&F 100330-A and four prototype antiepileptic drugs in mice and rats. Epilepsia 32:569SS9 1 198. Skeen, G.A., Wolf, H.H., Swinyard, E.A. and White, H.S. Flunarizine blocks KCI- induced Ca?2+ influx into cerebellar granule cells through an effect on glutamate-gated Ca2+ channels. Soc. Neurosci. Abstr. 17:921 (#369.5), 1991. 59 Sivenius, J., White, H.S., Wolf, H.H., and Swinyard, E.A. Antiepileptogenic effect of vigabatrin in corneal kindled rats. Epilepsia 32:40, 1991. 200. White, H.S., Wolf, H.H., Swinyard, E.A., Skeen, G.A. and Sofia, R.D. cological evaluation of felbamate as a novel anticonvulsant. §e02: 201. Epilepsia 33:564-572, White, H.S., Hunt, J., Wolf, H., Swinyard, E., Larson, O.M., Faich, E., Schousbce, A, and Krogsgaard-Larsen, P. Anticonvulsant activity of the GABA uptake inhibitor N- DPB-THPO. 202. A neuropharma- Epilepsia 33(3):116, 1992. White, H.S., Hunt, J., Wolf, H.H., Swinyard, E.A., Falch, E., Krogsgaard-Larsen, P. and Schousboe, A. Anticonvulsant activity of the y-aminobutyric acid uptake inhibitor N- 4,4-diphenyl-3-butenyl-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol. Pharmacol. 236:147-149, 1993. Eur. J. 24 203. Swinyard, E.A., Wolf, H.H., White, H.S., Skeen, G.A., Stark, L.G., Albertson, T., Pong, S.F., and Drust, E.G. Characterization of the anticonvulsant properties of F-721. Epilepsy Res. 15:35-45, 1993. 204. Brown, S.D., Wolf, H.H., Swinyard, E.A., Twyman, R.E., and White, H.S. anticonvulsant topiramate enhances GABA-mediated chloride flux. 34(2):122, 1993. The novel Epilepsia 2085. Harmsworth, W.L., Walf, H.H., Swinyard, E.A., and White, H.S. glycine receptor function. Epilepsia 34(2):92, 1993. 206. Gennings, C., Carchman, R.A., Carter, W.H., Jr., Sofia, R.D., and Swinyard, E.A. Analysis of anticonvulsant and neurotoxic responses to combination therapy with carbamazepine, felbamate and phenytoin by response-surface modeling. (Submitted). 207. Palmer, G.C., Harris, E.W., Cregan, E.C., Borrelli, A.R., Stagnitto, M.L., Garske, G.E., Kaiser, F.C., Napier, J.J., Murray, R.J., Griffith, R.C., Strand, J.C., Woodhead, J.H.,. Felbamate modulates White, H.S. and Swinyard, E.A. Preclinical evaluation of the anticonvulsant and neuroprotective properties of FPL 13950. (In preparation). 208. White,'H.S., Woodhead, J.H., Skeen, G.A., Tietz, E.I., Wolf, H.H. and Swinyard, E.A. The development of corneal-kindled seizures in rats as a model for complex partial seizures in man. Epilepsy Res. (In Revision). 209. Singh, N.A., Swinyard, E.A., Wolf, H.H., Torchin, C.D., Kapetanovic, |.M. and White, H.S. Effect of prototype anticonvulsants on N-methyl-D-aspartate-induced seizures in mice. J. Pharmacol. Exp. Ther. (In Preparation). 210. White, H.S., Woodhead, J.H., Swinyard, E.A., Wolf, H.H., Kane, J.M., Kehne, J.H., and Metcalf, G. Anticonvulsant profile of 5-(4-chlorophenyl)-2,4-dihydro-4-ethyl-3H- 1,2,4triazol-3-one (MDL 27,192) in rodent models of epilepsy. (In Preparation) 211. White, H.S., Experimental Woodhead, J.H., Franklin, M.R., Swinyard, selection, quantification and evaluation of Antiepileptic Drugs, Fourth Edition, (in press). E.A., and Wolf, anticonvulsants. H.H. In: Technical The Reports Early for Evaluation NINCDS Contract NO1-NS-5-2302 of Anticonvulsant Title Drugs Submi tted Authors Brain Swinyard, E.A. 1-15-75 Effects of Various Solvents on Anticonvulsant Activity of Phenytoin Swinyard, E.A. 2-25-75 Swinyard, E.A. Woodhead, Jose Swinyard, E.A. 9-22-77 Swinyard, E.A. 5-15-77 Swinyard, E.A. 5-18-78 Swinyard, E.A. 6-1-78 A Comparison of Setected Antiepileptic Drugs on Chemically Induced Seizures Swinyard, E.A. 1-17-78 The Profile of Anticonvulsant Activity and Acute Toxicity of 35001 and 35002 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A. 9-21-79 Profile Swinyard, E.A. 10-30-79 Swinyard, E.A. 10-10-79 Swinyard, E.A. 10-22-79 Swinyard, E.A. 11-30-79 Effects of Various Solvents on Excitability and Phenobarbital Reliability Maximal and Standard of i.v. Minimal Met Test for Disclosing Seizure Activity Operating University of Utah Development Procedures for Anticonvulsant the and 7-15-76 Drug Laboratory Internal Control Drug Development Study: Program Analysis of Laboratory How Much Chemical Is Anticonvulsant Work Flow Required of Anticonvulsant Acute Toxicity of 03046 Prototype Antiepileptic Activity and and 03055 and Drugs in Mice Some and Rats The Profile of Anticonvulsant Acute Toxicity of 17021 and Antiepileptic Drugs in Mice The Profile of Acute Toxicity Antiepileptic Activity and Some Prototype and Rats Anticonvulsant Activity and of 06140 and Some Prototype Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 09004 and Some Prototype Antiepileptic Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 13011 and 16144 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, 12-10-79 The Profile of Anticonvulsant Activity and Acute Toxicity of 13004 and Some Prototype Swinyard, 1-5-80 Swinyard, 2-1-80 The Profile of Anticonvulsant Activity and Acute Toxicity of 06114 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, 2-10-80 The Profile of Anticonvulsant Activity and Acute Toxicity of 14060 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard; 2-14-80 The Swinyard, 2-20-80 Swinyard, 8-6-80 Swinyard, 8-18-80 Swinyard, 3-29-80 Swinyard, 9-3-80 Swinyard, 9-5-80 Swinyard, 9-29-80 Antiepileptic The Profile Drugs in Mice and of Anticonvulsant Acute Toxicity of 16112 and Antiepileptic Drugs in Mice Profile of Profile Acute Anticonvulsant Toxicity Profile Acute Drugs Toxicity Antiepileptic Acute and Activity Some in Mice and 16117 in and Prototype Rats Activity Some Mice and and and Prototype Rats Anticonvulsant Activity and of 50008 and Some Prototype Drugs in Mice and of Anticonvulsant Toxicity Prototype of Drugs The Profile of Acute Toxicity Profile 41004 and Some Prototype and Rats of Anticonvulsant Antiepileptic The of and Activ%ty of Anticonvulsant Antiepileptic The Activity Some Prototype and Rats Acute Toxicity of 22026 and Antiepileptic Drugs in Mice The Rats of 40009, Antiepileptic Activity 40016 Drugs Rats and in and Some Mice and Rats The Profile of Anticonvulsant Acute Toxicity of 14031 and Antiepileptic Drugs in Mice The Profile of Anticonvulsant Acute Toxicity of 40037 and Antiepileptic Drugs in Mice Activity and Some Prototype and Rats Activity and Some Prototype and Rats Technical Reports for NINCDS Contract NO1-NS-1-2347 The Profile of Anticonvulsant Activity and Acute Toxicity of 54001 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., and Shenoy, A.K. 1-30-81 The Profile of Anticonvulsant Activity and Acute Toxicity of 09078 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., and Shenoy, A.K. 2-4-81 The Profile of Anticonvulsant Activity and Acute Toxicity of 49047 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., and Shenoy, A.K. 2-9-81 The Swinyard, 2-16-81 Profile Acute of Anticonvulsant Toxicity Antiepileptic The Profile Acute of 16084 Drugs and Activity Some in Mice Toxicity Antiepileptic of 17085 Drugs Prototype and of Anticonvulsant and Rats and Prototype and Rats of University Second Laboratory, Development E.A., H.H., 2-20-81 and A.K. Swinyard, E.A., Wolf, H.H., and Shenoy, A.K. 3-20-81 E.A., 5-10-81 Swinyard, Drug Wolf, H.H, Shenoy, Edition A.K., and Woodhead, Anticonvulsant Utah A.K. Swinyard, Wolf, and the for Procedures Operating H.H., Shenoy, The Profile of Anticonvulsant Activity and Acute Toxicity of 51006 and Some Prototype Antiepileptic Drugs in Mice and Rats Standard Wolf, E.A., Shenoy, Activity Some in Mice and Jose Duration Rats of Action (with of Evaluation Selected Derivatives Electroshock Seizure (ATS) of 14031B in Mice and Alcohol, Solvent Profile Acute on of Cannabidiol and by the Maximal Test in Mice Tween Brain 80 and Profile Swinyard, E.A., Wolkf Saline Excitability of Anticonvulsant Toxicity Antiepileptic The E.A. 7-8-81 and of 62043 Drugs and in Mice of Anticonvulsant Acute Toxicity of 10015 and Antiepileptic Drugs in Mice and 7-9-81 E.A. 8-3-81 in Mice Activity Some and e Swinyard, The Profile of Anticonvulsant Activity and Acute Toxicity of 06028 and Some Prototype Antiepileptic Drugs in Mice and Rats The Swinyard, addendum) Comparative Effect Neurotoxicity, Potency, Anticonvulsant and Prototype Swinyard, E.A., Wonlif S HER and 9-22-81 E.A., and 9-29-81 E.A., and 10-2-81 Swinyard, WoEEEE S Rats Activity and Some Prototype and Rats Swinyard, INGIIEEISHE The Profile of Anticonvulsant Activity and Acute Toxicity of 26020 and Some Prototype Antiepileptic Drugs in Mice and Drugs in Mice Wolf, H.H. and 10-6-81 and 10-9-81 and 10-14-81 and 10-12-81 Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 09028 and Some Prototype Antiepileptic Swinyard, and Rats Swinyard, Wolf, H.H. The Profile of Anticonvulsant Activity and Acute Toxicity of 46007 and Some Prototype Antiepileptic Drugs in Mice and Rats Wolf, The Profile of Anticonvulsant Activity and Acute Toxicity of 44003 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, WollsfE e ~Effect of Chronic Administration of 40037 on Body Temperature, Tolerance, and Liver Microsomal System in Rats 3 The Profile of Anticonvulsant Activity and Acute Toxicity of 53011 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, H.H. Swinyard, Wolf, 3-18-82 H.H. Woodhead, Swinyard, and 2-15-82 and 2-22-82 and 2-26-82 anQ 3-1-83 Swinyard, Wolf, H.H. and 10-20-82 Swinyard, Wolf, H.H. and 3-8-82 The Profile of Anticonvulsant Activity and Acute Toxicity of 61081 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, and 4-21-82 The Profile of Acute Toxicity Swinyard, and 5-28-82 Wolf, H.H. The Profile of Anticonvulsant Activity and Acute Toxicity of 43018 and Some Prototype Antiepileptic Drugs in Mice and Rats Wolf, The Swinyard, Profile Acute of Anticonvulsant Toxicity Antiepileptic of 62021 Drugs and Activity Some in Mice and Prototype and Phase VII Report on 03046 The Profile of Anticonvulsant Activity and Acute Toxicity of 17014 and Some Prototype Antiepileptic Antiepileptic The Effect Drugs in Mice and of VPA on Anticonvulsant in Mice (00008) Activity and and H.H. Swinyard, Wolf, H.H. Rats Anticonvulsant Activity and of 62019 and Some Prototype Drugs Wolf, H.H. Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 63020 and Some Prototype Antiepileptic Drugs in Mice and Rats Special Swinyard, Wollifis ik Wolf, H.H. Rats 2-en (88044) Swinyard, 256 6-15-82 The Profile of Anticonvulsant Activity and Acute Toxicity of 56098 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H. and 7-2-82 The Profile of Anticonvulsant Activity and Acute Toxicity of 68022 and Some Prototype Swinyard, EA nd 7-2-82 Swinyard, E.A., Wolf, H.H. and 8-5-82 Swinyard, Antiepileptic Drugs in Mice and Wolf, Rats The Effect of Acute and Chronic Administration of 03055 on Anticonvulsant Activity and on Various Neurochemical Parameters of Mouse Blood, Brain, Liver, and Salivary & Glands. Addendum to Report H.H. No The Profile of Anticonvulsant Activity and Acute Toxicity of 64005 and Some Prototype Antiepileptic Drugs in Mice and Rats EAT and 8-10-82 NGRS Effect of Selected Doses of 84061 on Neurotoxicity and Anticonvulsant Activity Swinyard, ESARS Wolf, H.H. and 8-16-82 (MES and sc Met tests) as Time a Function of The Profile of Anticonvulsant Activity and Acute Toxicity of 57032 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, The Profile of Anticonvulsant Activity and Acute Toxicity of 78064 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, BN Wl [kl Addendum to Report Studies on 57032. No. Swinyard, Addendum to Report Studies on 78064. No. Effect 41. VII Wolf, 42. of Benzodiazepines [3H]Flunitrazepam Phase Binding Phase VII Citric Acid/KHZPO Solution Vehicle on the EDgO's of 4 Prototype Antiepileptic Profile T and 9-9-82 H.H. and EsARand 9-14-82 9-28-82 H.H. Swinyard, ERAS WollkSEHE on Bffect of Used as a The Wolf, ESAR Swinyard, EAR Swinyard, Woodhead, E.A., T and 9-28-82 11-24-82 and 1-18-83 J. Drugs of Anticonvulsant Acute Toxicity of 55051 and Antiepileptic Drugs in Mice Activity and Some Prototype and Rats Wolf, EA, H.H. , Chweh, A.Y., & Woodhead, Swinyard, Jis 2-24-83 The Profile of Anticonvulsant Activity and Acute Toxicity of 75073 and Some Prototype Antiepileptic Drugs in Mice and Swinyard, Rats Wolf, H.H., A.Y., & Woodhead, s The Profile of Anticonvulsant Activity and Acute Toxicity of 14001, 14002, and Some Prototype Antiepileptic Drugs in Mice and E.A., Chweh, Swinyard, E.A., Wolf, H.H., Chweh, A.Y., Rats 3-2-82 3-7-83 & Woodhead, J. The Profile of Anticonvulsant Activity and Acute Toxicity of 78222 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, Wolf, A.Y., ‘ E.A., 3-11-83 H.H., Chweh, & Woodhead, J. Comparative Procedures: (Parke-Davis) Neurotoxicity of 62021 Horizontal Screen vs Rotorod The Effect of the 03055 on Three in Three in vitro by Two Swinyard, E.A. 5-6-83 Swinyard, E.A. 5-6-83 Swinyard, E.A., 6-14-83 (Utah) Acute Administration of vivo-induced Sejzures and Parameters The Anticonvulsant Activity N,N-Dimethylglycine in Mice of Wolf, A.Y., H.H., Chweh, & Woodhead, us Effect of 101028 Metrazol Seizure on Intravenous Threshold in Mice Swinyard, Wolf, A.Y., E.A., 6-28-83 H.H., Chweh, & Woodhead, J. The Profile of Acute Toxicity Antiepileptic Anticonvulsant Activity and of 93020 and Some Prototype Drugs in Mice and Rats Swinyard, Wolf, A.Y., E.A., 6-16-83 H.H., Chweh, & Woodhead, J. Comparative Effectiveness of Prototype Antiepileptic Agmats and Some Calcium Blockers Against 4-Aminopyridine-Induced Swinyard, E.A., Wolf, H.H., Chweh, A.Y., & Woodhead, Seizures i The in Profile Mice of Anticonvulsant Acute Toxicity of 87018 and Antiepileptic Drugs in Mice Activity and Some Prototype and Rats Swinyard, Wolf, A.Y., E.A., 8-2-83 8-5-83 H.H., Chweh, & Woodhead, J. The Acute Profile of Toxicity Antiepileptic Anticonvulsant of 87016 Drugs and in Mice Activity Some and and Prototype Rats Swinyard, Wolf, A.Y., U E.A., H.H., Chweh, & Woodhead, 9-8-83 The Profile of Anticonvulsant Activity and Acute Toxicity of 94028 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, Wolf, A.Y., 9-12-83 E.A., H.H., Chweh, & Woodhead, J. The Profile Acute of Anticonvulsant Toxicity Antiepileptic The Profile Acute of 86034 Drugs and Activity Some in Mice Toxicity Antiepileptic of Drugs 90128 Prototype and of Anticonvulsant and Rats Activity Some in Mice and and Prototype and Rats Swinyard, E.A., Wolf, H.H., Chweh, A.Y., & Woodhead, s 10-10-83 Swinyard, E.A., Wolf, H.H., Chweh, A.Y., & Woodhead, 1-20-84 J. The Profile Acute of Anticonvulsant Toxicity Antiepileptic of Drugs 99012 and Activity Some in Mice and Prototype and Rats 2-22-84 Swinyard, E.A., Wolf, H.H., Chweh, A.Y., & Woodhead, J. The Profile of Anticonvulsant Activity and Acute Toxicity of 106011 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., Chweh, A.Y., & Woodhead, J. 3-8-84 The Swinyard, E.A., Wolf, H.H., Chweh, 3-8-84 Profile Acute of Anticonvulsant Toxicity Antiepileptic of Drugs 106024 and in Mice Activity Some and and Prototype A.Y., Rats & Woodhead, J. Technical Reports for NINCDS Contract NO1-NS-4-2361 The Early Evaluation of Anticonvulsant Drugs The Profile of Anticonvulsant Activity and Acute Toxicity of 103017 and Some Prototype Antiepileptic Drugs in Mice and Rats M.R., Anticonvulsant Activity and of 79146 and Some Prototype The Profile of Acute Toxicity Antiepileptic Drugs in Mice and Rats of 78064 in i Activity t Me- Test J. 6-1-84 E.A., Wolf, H.H., Chweh, oMo s Prremiels & Woodhead, Swinyard, E.A. Wolf, H.H. and J. 6-1-84 Mice Effect of 111020 on the Anticonvulsant Activity of Diazepam as Measured by the sc & Woodhead, Swinyard, M.R., Effect of Three Solvents on the Neurotoxicity and Anticonvulsant 5-24-84 Swinyard, E.A., Wolf, H.H., Chweh, A.Y., Franklin, in Mice Swinyard, E.A. ' 6-7-84 The Profile Acute of Anticonvulsant Toxicity Antiepileptic of 89057 Drugs and Activity Some in Mice and Prototype and Rats Swinyard, E.A., Wolf, H.H., Chweh, A.Y., Franklin, M.R., The Profile of Anticonvulsant Activity and Acute Toxicity Antiepileptic of 106014 Drugs and Some in Mice and Prototype Rats & Woodhead, of Anticonvulsant Acute Toxicity of 90066 and Antiepileptic Drugs in Mice Activity and Some Prototype and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 71043 and Some Prototype Antiepileptic Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 113002 and Some Prototype Antiepileptic Drugs in Mice and Rats & Woodhead, Profile Acute of Anticonvulsant Toxicity Prototype Rats of 94057, Antiepileptic Activity 40016, Drugs and and Some in Mice and The Profile of Anticonvulsant Activity and Acute Toxicity of 106083 and Some Prototype Antiepileptic Drugs in Mice and Rats A.Y., Franklin, M.R., & Profile Acute of Anticonvulsant Toxicity Antiepileptic The Profile of of 106085 Drugs in and Activity Some Mice and Anticonvulsant Acute Toxicity of 92080 and Antiepileptic Drugs in Mice and Prototype Rats Activity and Some Prototype and Rats Woodhead, A.Y., Franklin, M.R., & A.Y., Franklin, M.R., & 11-26-84 J. 12-17-84 Swinyard, E.A., Wolf, H.H., Chweh, AR Erankdaint & Woodhead, Swinyard, J. 1-25-85 E.A., Wolf, ARYe H.H., Chweh, EranlkIfing M.R., & Woodhead, J. 2-20-85 Swinyard, E.A., Wolf, H.H., Chweh, AR Eranikdiaint & Woodhead, Swinyard, Wolf, AR M.R., J. 2-28-85 E.A., H.H., Chweh, Firanialbiing & Woodhead, J. Swinyard, Wolf, H.H., ARG M.R., Eranikilsing & Woodhead, Chweh, AR Eira nikilkiink M.R., & Swinyard, 3-15-85 E.A., Antiepileptic Rats J. Woodhead, H.H., and 9-14-84 Swinyard, E.A., Wolf, H.H., Chweh, Wolf, in Mice J. Woodhead, The Profile of Anticonvulsant Activity and Acute Toxicity of 98049 and Some Prototype Drugs 9-12-84 Swinyard, E.A., Wolf, H.H., Chweh, M.R., The J. Swinyard, E.A., Wolf, H.H., Chweh, M.R., The 9-10-84 " Eranikiiin, M.R., The Profile J. Swinyard, E.A., Wolf, H.H., Chweh, A The Profile of Anticonvulsant Activity and Acute Toxicity of 96009 and Some Prototype Antiepileptic Drugs in Mice and Rats 7-25-84 J. 6-18-85 E.A., Chweh, Woodhead, J. Activity of Anticonvulsant Profile The and Acute Toxicity of 69036 and Some Prototype Antiepileptic Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 118002 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, Wolf, H.H., Chweh, ANy Erankiltinl, M.R., & Woodhead, AN Erankiiiinl; M.R., & Woodhead, Wolf, H.H., Antiepileptic AR Enankiin M.R., & Woodhead, in Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 123072 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, of Anticonvulsant Activity and Acute Toxicity of 108038 and Some Prototype Antiepileptic Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 122055 and Some Prototype Antiepileptic Drugs in Mice and Rats The Effect of Potency Anticonvulsant After 90128 Solvents Two Oral on the of Three Administration Lots in of Rats in Mice and Antiepileptic Drugs A Comparative sant Activity Evaluation of the and Neurotoxicity Optical Mice and Isomers Rats (117054 and & 10-25-85 Chweh, Woodhead, J. 11-1-85 J. 11-15-85 E.A., Wolf, H.H., A.Y., Franklin, M.R., & Woodhead, Chweh, J. 12-11-85 Swinyard, E.A., Wolf, H.H., Chweh, AR, N Eranikising & Woodhead, J. 12-19-85 Swinyard, E.A., Wolf, H.H., Chweh, ARYer N Erankilsing M.R., & Woodhead, J. 3-4-86 Swinyard, E.A., Wolf, H.H., Chweh, AR FrankilsinSeMaRS & Woodhead, The Profile of Anticonvulsant Activity and Acute Toxicity of 117054 and Some Prototype J. E.A., Swinyard, M.R., The Profile of Anticonvulsant Activity and Acute Toxicity of 113024 and Some Prototype Antiepileptic Drugs in Mice and Rats 9-13-85 Swinyard, E.A., Wolf, H.H., Chweh, AR Eranikiin M.R., The Profile J. Swinyard, E.A., Wolf, H.H., Chweh, The Profile of Anticonvulsant Activity and Acute Toxicity of 122026 and Some Prototype Drugs 7-31-85 E.A., J. 3-7-86 Swinyard, E.A., Wolf, H.H., Chweh, Rats Mellos M.R., Anticonvulof Two Swinyard, E.A., Wolf, H.H., Chweh, ASYESSS Erain kilsing, M.R., & Woodhead, J. 117055) in [FRERRITR, & Woodhead, J. 3-5-86 10 The Profile Acute of Anticonvulsant Toxicity Antiepileptic of 129018 Drugs in Activity and and Some Prototype Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 105006 and Some Prototype Antiepileptic Drugs in Mice and Rats AR R ik i M.R., & Woodhead, Swinyard, Wolf, H.H., 5-13-86 Chweh, A S Eran kSN M.R., & Woodhead, Swinyard, E.A., Wolf, H.H., Chweh, Antiepileptic AR M.R., in Mice and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 119008 and Some Prototype Antiepileptic Drugs in Mice and Rats Eran kil & Woodhead, Swinyard, Wolf, A M.R., J. E.A., The Profile of Anticonvulsant Acfivity and Acute Toxicity of 119009 and Some Prototype Drugs 4-29-86 Swinyard, E.A., Wolf, H.H., Chweh, J. 6-23-86 J. 9-17-86 E.A., H.H., Chweh, Erankiang & Woodhead, J. The Profile of Anticonvulsant Activity and Acute Toxicity of 128054 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., Chweh, Moo Framikllie M.R., & Woodhead, J. 8-28-86 The Swinyard, E.A., Wolf, H.H., White, FSSTRS EranikilsnamER: & Woodhead, J. 11-24-86 The Profile of Anticonvulsant Activity and Acute Toxicity of 59076 and Some Prototype Swinyard, E.A., Wolf, H.H., White, 1-5-87 Antiepileptic RS Era nikiliin & Woodhead, J. Profile Acute of Anticonvulsant Toxicity Antiepileptic of 126025 Drugs Drugs and Activity Some in Mice and in Mice and Prototype Rats and Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 136071 and Some Prototype Antiepileptic The Profile of Acute Toxicity Antiepileptic The Acute Profile in Mice and Rats Anticonvulsant Activity and of 121028 and Some Prototype Drugs in Mice and of Anticonvulsant Toxicity Antiepileptic Drugs of Drugs 141057 and in Mice Activity Some and and Prototype Rats The Profile of Anticonvulsant Activity and Acute Toxicity of 139025 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., White, oo n FremislTng hilsRs & Woodhead, J. 5-11-87 Swinyard, E.A., Wolf, H.H., White, 6-16-87 H.S., Franklin, & Woodhead, J. Rats = SR Swinyard, M.R. E.A., 7-21-87 Wolf, H.H., White, H.S., Franklin, M.R. & Woodhead, J. Swinyard, E.A., Wolf, H.H., White, HESAENErankisins MRS & Woodhead, J. 7-29-87 11 The Profile of Anticonvulsant Activity and Acute Toxicity of 82013 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., White, disSEn M Erankiling MR & Woodhead, The Profile of Anticonvulsant Activity Acute Toxicity of 137022, 137021, and Prototype Antiepileptic Drugs in Mice and Rats The Profile Acute of Anticonvulsant Toxicity Prototype and Rats of 77305, Drugs and Swinyard, Some Activity 77301, Antiepileptic and and Some to 82013 - Phase Activity and Neurotoxicity, and i.v. Threshold of 157034, Lidocaine in Mice Rats The Profile Acute Some Prototype and Rats Second Edition The Profile of Acute Toxicity Antiepileptic of Metrazol Woodhead, White, M.R. J. and Rats Whiite' E.A., 4-6-88 Wolf, H.H., White, HISSESREran kkinE SMERES & Woodhead, J. Swinyard, E.A., Wolf, H.H., White, HEESERE Frankiliing M. R: & Woodhead, J. 5-3-88 and Swinyard, E.A., Wolf, H.H., White, H.S., Franklin, M.R. & Woodhead, J. 8-8-88 Swinyard, 9-30-88 and in Mice Anticonvulsant Activity and of 06140 and Some Prototype and 2-22-88 and 141010, Drugs Malks E.A., HEkR S Swinyard, Activity hiites HESE EranikinERMER & Woodhead, J. : in Mice RN Swinyard, Wollifa 1-19-88 E.A., eSoo BT & Woodhead, J. and 136068, Antiepileptic Drugs Franklin, WollifsRH Seizure Mexiletine, 75073, H.S., Swinyard, Activity, of Anticonvulsant Toxicity H.H., 12-1-87 The Profile of Anticonvulsant Activity Acute Toxicity of 134004 and Some Prototype Antiepileptic Drugs in Mice and 11-18-87 E.A., V The Profile of Anticonvulsant Activity Acute Toxicity of 125026 and Some Prototype Antiepileptic Drugs in Mice and Rats Anticonvulsant J. Wolf, & Rats The Acute Woodhead, Swinyard, The Profile of Anticonvulsant Activity and Acute Toxicity of 96009, 96010, and Some Prototype Antiepileptic Drugs in Mice and 11-18-87 HISSIES S Brankiiins s MoR: Acute Toxicity of 142019 and Some Prototype Antiepileptic Drugs in Mice and Rats Addendum 8-20-87 E.A., Swinyard, E.A., Wolf, H.H., White, in Mice of Anticonvulsant J. Wolf, H.H., White, ISR BrainikilGinsm iSR & Woodhead, J. & The Profile 8-13-87 E.A., Wolf, H.H., White, H.S., Franklin, M.R. & Woodhead, J. 12 Second Edition The Profile of Anticonvulsant Activity and Acute Toxicity of 137021, 137022, and Some Prototype Antiepileptic Drugs in Mice Wolf, HivSas and & Woodhead, Rats The Profile Acute of Anticonvulsant Toxicity Prototype of 77300, Activity 77305, Antiepileptic Drugs and and Some in Mice and Rats Swinyard, of Anticonvulsant Activity and Swinyard, H.S., Franklin, Swinyard, The Profile of Anticonvulsant Activity .and Acute Toxicity of 145016 and Some Prototype Antiepileptic Drugs in Mice Swinyard, and Some in Mice E.A., H.H., Wolf, The Profile of Anticonvulsant Activity and Acute Toxicity of 148034, 166032, 169018, Prototype and Antiepileptic Drugs Rats J. Wolf, Acute Toxicity of 92009, 92010, and Some Prototype Antiepileptic Drugs in Mice and Rats Rats 12-5-88 H.H., White, Branklin, M.R. & Woodhead, The Profile and E.A., 12-5-88 White, M.R. J. E.A., H.H., ; 5-30-89 White, HSSER R BranikitinsmeRs & Woodhead, J. E.A., 7-12-89 Wolf, H.H., White, H.S., Franklin, M.R. & Woodhead, J. Swinyard, E.A.:, 7-14-89 Wolf, H.H., White, HESSE B ralniiclSinte SR & Woodhead, J. Technical Reports for NINDS Contract NO1-NS-9-2328 The Early Evaluation of Anticonvulsant Drugs The Profile Acute of Anticonvulsant Toxicity of 106011, 156004, 172006, and Some Prototype Drugs in Mice and Rats Some Antiepileptic and and Swinyard, E.A., Wolf, H.H., White, HESH Brankidiing MRS & Woodhead, J. 3-12-90 and Swinyard, E.A., Wolf, H.H., White, 5-7-90 Antiepileptic Anticonvulsant Activity of 105006, 142013, and in Mice 1-29-90 and 158001, The Profile of Acute Toxicity Prototype Swinyard, E.A., Wolf, H.H., White, HSSER R Erankitin, MM RS & Woodhead, J. Activity Drugs Rats The Profile of Anticonvulsant Activity Acute Toxicity of 06140 and Some Prototype Antiepileptic Drugs in Mice S s Eranicliing s MERE & Woodhead, and Rats The Profile of Anticonvulsant Activity and Swinyard, J. E.A., Acute Toxicity of 169021 and Some Prototype Antiepileptic Drugs in Mice and Rats Wolf, H.H., White, SIS EranialsinsRMERS & Woodhead, J. The Profile of Acute Toxicity Swinyard, Prototype and Rats Anticonvulsant Activity and of 94057, 154013, and Some Antiepileptic Drugs in Mice E.A., Wolf, H.H., White, H.S., Franklin, M.R. & Woodhead, J. 7-23-90 7-23-90 13 The Profile of Andconvulsant Actvity and Swinyard, E.A., Wolf, H.H., Acute Toxicity of 163008, 163012, and Some Prototype Andepileptic Drugs in Mice and Rats White, H.S., Franklin, M.R., & Woodhead, J. The Profile of Antconvulsant Activity and Acute Toxicity of 166012 and Some Prototype Andepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., White, H.S., Franklin, M.R., & Woodhead, J. 10-1-90 The Profile of Anticonvulsant Activity and Swinyard, E.A., Wolf, H.H., 10-1-90 Acute Toxicity of 169030 and Some Prototype White, H.S., Franklin, M.R., Antiepileptic Drugs in Mice and Rats & Woodhead, J. Effect of ADD 075073, Mexilitine, and Lidocaine on Minimal Seizure Threshold of Mice Swinyard, E.A.,Wolf, H.H., 7-23-90 4-18-91 White, H.S., & Woodhead, J. The Profile of Anticonvulsant Activity and Swinyard, E.A., Wolf, H.H., Acute Toxicity of 187002 and Some Prototype Antepileptic Drugs in Mice and Rats White, H.S., Franklin, M.R., The Profile of Anticonvulsant Activity and Swinyard, E.A., Wolf, HH., Minimal Toxicity of 178037 and Some Prototype Antiepileptic Drugs in Mice and Rats White, H.S., Franklin, M.R., The Profile of Anticonvulsant Activity and Minimal Toxicity of 138044, 138045, 145001, and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., White, H.S., Franklin, M.R., & Woodhead, J. 12-5-91 The Profile of Anticonvulsant Activity and Swinyard, E.A., Wolf, H.H,, White, H.S., Franklin, M.R., & Woodhead, J. 12-5-91 Swinyard, E.A., Wolf, H.H., 12-5-91 Minimal Toxicity of 154006, 168020, and Some Prototype Antdepileptic Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Minimal Toxicity of 172014, 181030, and Some Prototype Andepileptic Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Minimal Toxicity of 182013 and Some Prototype Andepileptic Drugs in Mice and Rats 11-4-91 & Woodhead, J. 12-5-91 & Woodhead, J. White, H.S., Franklin, M.R., & Woodhead, J. Swinyard, E.A., Wolf, H.H., White, H.S., Franklin, 1-22-92 M.R., & Woodhead, J. Swinyard, E.A., Wolf, HH,, White, H.S., Franklin, M.R., & Woodhead, J. 5-4-92 The Profile of Anticonvulsant Activity and Minimal Toxicity of 169026 and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, HH,, White, H.S., Franklin, M.R., 5-28-92 The Profile of Anticonvulsant Activity and Minimal Toxicity of 175001, 175002, and Some Prototype Antiepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., The Profile of Anticonvulsant Activity and Minimal Toxicity of 196022 and Some Prototype Antepileptic Drugs in Mice and Rats & Woodhead, J. White, H.S., Franklin, M.R., ‘ & Woodhead, J. 5-28-92 14 The Profile of Anticonvulsant Actvity and Minimal Toxicity of 185137 and Some Prototype Antepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., White, H.S., Franklin, M.R., 7-8-92 & Woodhead, J. The Profile of Anticonvulsant Activity and Minimal Toxicity of 164047 and Some Prototype Antepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., White, H.S., Franklin, M.R., & Woodhead, J. 9-4-92 The Profile of Anticonvulsant Activity and Minimal Toxicity of 199002 and Some Prototype Antepileptic Drugs in Mice and Rats Swinyard, E.A., Wolf, H.H., 9-4-92 The Profile of Anticonvulsant Activity and Minimal Toxicity of 205103 and Some Prototype Antiepileptic Drugs in Mice and Rats The Profile of Anticonvulsant Activity and Minimal Toxicity of 211010 and Some Prototype Antepileptic Drugs in Mice and Rats White, H.S., Franklin, M.R., & Woodhead, J. Swinyard, E.A., Wolf, H.H., 10-5-92 White, H.S., Franklin, M.R., & Woodhead, J. Swinyard, E.A., Wolf, HH,, White, H.S., & Woodhead, J. 1-27-93 MISCELLANEOUS Ewart PUBLICATIONS A. Swinyard Leonard, E. O. and Swinyard, basis for science teachers. 332-333, - . OF E. A. Am. J. .193%. Pharmacy as a Pharm. eltiels - 3, a Swinyard, E. Beicing. Am...J. A. and Clayton, Pharm. R. P. Educ., 4 Prescription 5I80=5/847 8 1i9/A108 Swinya;d, E. A. and Clayton, R. prescription pricing schedule. 1940, 3,14, P. University of Idaho Rocky Mountain DIacTea Swinyard, R. P. PreScripEaioneplitc i cis R. P. Prescription El E. A. and Farmaceutico, Swinyard, E. schedule. €llayEan, 1940. A. and Rocky "R. prescription Pl Clayton, Clayton, Mountain and Swinyard, pricing BEacE S PRaEmiNEd- Swinyard, E. A. Drug., SB22, E. schedule. pricing 1940 A. A J. Am:. Pharm. New price simple flexible Assoc. 20 s 4708 L G4l and Clayton EeplprescripEionsidevised. R. P. Drug Topics, system 85,.22, 1941. SWinyard, E. A. and Clayton, R. P. New price system EgE prescriptions devised. (El Farmaceutico, 18, 20, Swinyard, E. A. A over a twenty-five 8i86=3905 nG. gy comparison of year period. 1942. pharmacy curriculums Am. J. Pharm. Educ., 11945 AP A deE ine s, - L. D B Syinviars from of Pharmacognosy separation Am. program. instructional J. complete the PARpilieal For tbe in Pharmacology Pharm. Educ., 719-724, s 1947. B, E. Swinyard, Swinyard, Ehasmic New E. A. Ute, 2, New 4., prescription Ute, Pharmic Analgesics. E2% A. 1, 4, 1949. prescription 1949. items: items: Antiepileptics, ' Antihistaminics. e 14. Swinyard, E. Pharmic Ute, Weaver, L. A. New 3, C. 4, and prescription 1949. Swinyard, E. items: - Antibiotics--Should Pharmic Ute, 2, 2% L9380 Swinyard, E. Digitoxin. A. items: New Pharmic A. cost New 25 prescription influence pPrescription Ute, Antibiotics. Sl items: therapy. Digitalis 95 0% 16. Swinyard, E. Pharmic Ute, e SwWinyard, E. A. and Hiner, L. D. An experiment in teaching drugstore management. Am. J. Pharm. Educ., 15, 18 22-27, A. B prescription e iSO E. A. (Levophed). New prescription Pharmic IOES Swinyard, E. A. blocking agents. 20 Orr, E. Ute, R4 Swinyard, and E. resins. 22 Swinyard, 231 E. Pharmic Hather Wy EALNP 1952 Swinyard, Swinyard, SpNUEah. A E. E. afid Ute, Sp \Am. A. The colleges 1952. Al Hiner, 4, .4, Swinyvard, prescription A. items. =6l EIO prescription Ute, SSpESand Seeietics..” 25 New A. Heah- ' pharmacy: 24. A. Pharmic Swinyard, Antabuse. 1-Norepinephrine e New prescription items. Pharmic Ute, SoauNeel 2,004 of prescription surveys to BhcemNEduet 16, 2515256, 20 items. 1951. Swinyard, J. New S vs. Pharm. of and importance pharmacy. items. Am. J. Ion-exchange LGSk L. D. Prescription A. Prof%lg trends in 1952. E. Pacific survey. Pharmaceutical J. value Adrenergic ,1 10150 Educ., education 17, of modern. Drug and 61-63, L. D. Prescription E. A. and Hiner, Pharmic Ute, 5, 4, 1953. Review, professional 1953. pricing trends 26 Swinyard, E.-A. Correlation of pharmacognosy and pharmacology: Am. J. Pharm. Educ., Section F, Teachers Seminar on Pharmacognosy and Related Subjects, University of Ueah!, #2.95 31, 27- Sw1nyar§,'E. prerequisite Utah, College of A. to Human physiology and/or pharmacognosy. Section Swinyard, E. A. Report of Am-“J." Pharm. Educ., NG 2O Swinya;d,.E. A. prescription trends. Redesehiy HS N andl dppEeach e as Swinyard, A. pharmacology. 82 PEiee 33, (R L., E.- Pharmic trends‘revealed in 6, Ute, and 480-486, 1954. A. ‘Utdh U.Ph.A. Bulletin 1954. What D.. L. 6,'2, E. swinyard, new 1954 Hiner, and Utah offers pharmacognosy €., survey. 13, lfi' study. 1954. Diamox BEdueh; "Pharmic and’ A.. graduate reveals 2-4, 6, Ute, of on Survey Ute, Swinviard, €ampanella, Jr. D. Pharmic preseription? WoElkman, L. Correlation A., anatomy as a C, Teachers the committee 28 = G2BRSO SIS Hiner, Cit RN Related Subjects, University Salt Lake City, Utah, 1953. AmieJie s PRiaEms E. Swinyard, and diuretiec. " E. Lake b 28. DL Salt ’ Seminar on Pharmacognosy and gENtlEahli€allege 'of Pharmacy, S01 Pharmac prescription 65, News, 8 95612 34. Bulletin 35 Si6k Bulletin 581 Swinyard, A. E. Swinyard, Parkinson's E. A. A Temposil: 2, 65, News, 544-548, 20, Educ., Pharm. Recent disease. Misuses, and U.Ph.A. 11915168 1-2, 65, News, U.Ph.A. 61 in the five year program Am. and public health. sciences Biological E- A. Swinlyard, first aid, pharmacology, physiology, J. Siee iS5 Barbiturates-Uses A. E. Compounds, Insulin-Sparing éi, News, Swinyard, Bulletin A. E. Swinyard, 1956. new keep sober U.Ph.A. drug. 1956. advances U.Ph.A. in the Bulletin treatment News, 65, of 1, 1956. 89 40. Duke, V. W. and Swinyard, E. A. éé'escr Pr e iption pricing schedule. Swinyard, 5 U.Ph.A. E. A. New Bulletin Swinyard, U.Ph.A. E. Drugs, ; News, A. new 85 The U.Ph.A. U.Ph.A. ull Bul eti let in terms, 45,1957. Chlorothiazide: Bulletin News, new ST to responsibili ili ties. ti I A News, . new diuretic agent. 119581 42. Swinyar?, E. A. Laboratory evaluation of drugs. Proceedings Teacher's Seminar on Pharmcology, University of Washington Seattle, p. 59-60, 1957. 43. Swinyard, leyel. E. Reawel, Supplemental 'Proceedings University 44. A. ‘Ts of Teacher's Washington, D ; Swiinyar=cli, S S the teacher's seminar on Seminar on Pharmacology, RN 2 =27 570 MO 57 Seminar Seattle, AT at on the graduate Pharmacology, PRSP Sind sl pharmacology. University of , s ERSIR IS 78O Summary of Proceedings Teacher's Washington, Seattle, SWiinyardyNEIN Prescription AN Workman!, R. L., and Hiner' L& Do pharmacy in Utah - 1957, Pacific Drug Review, Swinyard, 196108 T E. A. Ute, Swinyard, E. A. 70, 14, 1958. From the Achieving old Swinyard, E. licensure examination Prec A. The 20 thhAnnual to depth BrisEeacEon R EemasicsEERNAT 48. training SIS the in the Meeting, Pharmic of 8247 S didid pharmacology recommendation District O pharmacology. Phiatem SN Ed. relationship and new. 8, of A.A.C.P. TESIOI6I0F, to the the N.A.B.P. and N.A.B.P., 8GN 498 SwiimyaEARE of Proceedings isi0k RS AN 22nd NABEPR22, 158-161, Swinyard, E. and Graduate A. at S Eemosrow Meeting, Annual iintgraduateeducatiion’. District 8, AACP and 1963. Graduate Study Phaem-SSEdi-y s 28, ook in 94-97, Enrollment Member 1964. Data, Colleges, September, 1964-65. Am. 1963, J. SIS Swinyard, 1964, and Am. J. E. A. Graduate enrollment data, September, graduate Study in member colle ESTRRIN0I6I5EHEgI6 16R: Pharm. Ed. 29, 107-111, 1965. 3 Swinyard, Programs, E. A. Am. J. Report Pharm. of the Committee Ed. 28522064, on Graduate 53. Swinyard, Programs. E. A. Am. J. Report Pharm. of the Committee on Ed. 290 408 T 9658 Graduate 54. Swinyard, E. Book 553 Swinyard, E. A. The page 7, Winter 1970. Swinyard, GG E. A. A. Review "new" curriculum. Involvement, Pharmic Pharmic Ute, ea,; page 25, 2, Fall Swinyard, E. A. H. Ward McCarty--Friend and BEah Pharmacy Digesit, 80, 3-4, March 1971. Associate, Swinyard, E. Workshop “Emerging Roles MarEcehs4=6,, A., Editor. of the Proceedings Pharmacist" of the University of Utah, 1971 7~ 598 Sweithiy.a LR WHnEerNand 60. Swimyiardy,» S PE IR G A h o S edng NSpsan i lioiye ESVATS A0 SwinyaEcdyE Ay NEe vous il FoEsittP M Phidrmilc page Ute, Pharmic practice? Uites, 2 AT eeubll B=Tp S Howaw R toNpay G2 E. Swinyard, SPiE 1 RIS 1 A. 58 Swilnyasd), E. AL 29, PharmicUte; education. Continuhang SalCiyiae Job prospects. Pharmic Ute, 4, page Ute, Pharmic page ESHBINIEG 7 St 64. Swinyard, thanks. E. A. Many E. A. Continued E. A. Wisdom Pharmic Ute, AVNS page prhing ROA 65E Swinyard, progress. Pharmie Ute, page iEra 1 MIB ORI 66. Swinyard, 4, 45, September 1974. in All Things. New Era Magazine, 4, 67. 68. 69. Swinyard, E. A. A period RageldPIS BRI NG 1975 Swinyard, E. page 4, Fall A. A 1975. Svinyard, R, . Spring 70. RIS Swinyard, Swinyard. E. A. Dean E. A. Proceedings H. H. €linical July E. 13-16, A. Wolf, Pharmaecy Pharmic Pharmic ey Ute, Ute,'page 4, of Pharmic the First Education, Ute, page 4, International University of 1976. Research Pharmacy: Looking Educ., 409-414(1977). 41, Pharmic : en Minnesota, growth? decision. retrospect.' 1976. Cengresst 72 In for no 1976. Swinyard, Kall SRS time of and Graduate Back--Looking Education Forward. Am. J. in Pharm.