Bilateral Tonic Pupils Due to Antidisialoganglioside Antibody Immunotherapy for Neuroblastoma
| Title | Bilateral Tonic Pupils Due to Antidisialoganglioside Antibody Immunotherapy for Neuroblastoma |
| Creator | C. Swiston; A. Jebaraj; S. Vegunta; J. Warner |
| Affiliation | John A. Moran Eye Center, Salt Lake City, Utah |
| Abstract | Atonic pupil results from postganglionic parasympathetic pupillomotor denervation, leading classically to mydriasis, poor reaction to light with or without preservation of constriction to accommodation (light-near dissociation), and cholinergic hypersensitivity. |
| Subject | Atonic Pupil; Mydriasis |
| Date | 2023-06 |
| Date Digital | 2023-06 |
| References | 1. Sarao MS, Elnahry AG, Sharma S. Adie Syndrome. Treasure Island, FL: StatPearls Publishing, 2021. 2. Bartholomew J, Washington T, Bergeron S, Nielson D, Saggio J, Quirk L. Dinutuximab: a novel immunotherapy in the treatment of pediatric patients with high-risk neuroblastoma. J Pediatr Oncol Nurs. 2017;34:5-12. 3. Tse BC, Navid F, Billups CA, O'Donnell T, Hoehn ME. Ocular abnormalities in patients treated with a novel anti-GD2 monoclonal antibody, hu14.18K322A. J AAPOS. 2015;19:112- 115. 4. Kremens B, Hero B, Esser J, Weinel P, Filger-Brillinger J, Fleischhack G, Graf N, Grüttner HP, Niemeyer C, Schulz A, Wickmann L, Berthold F. Ocular symptoms in children treated with human-mouse chimeric anti-GD2 mAb ch14.18 for neuroblastoma. Cancer Immunol Immunother. 2002;51:107-110. 5. Svennerholm L, Boström K, Fredman P, Jungbjer B, Lekman A, Månsson JE, Rynmark BM. Gangliosides and allied glycosphingolipids in human peripheral nerve and spinal cord. Biochim Biophys Acta. 1994;1214:115-123. |
| Language | eng |
| Format | application/pdf |
| Type | Text |
| Publication Type | Journal Article |
| Source | Journal of Neuro-Ophthalmology, June 2023, Volume 43, Issue 2 |
| Collection | Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher | Lippincott, Williams & Wilkins |
| Holding Institution | Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management | © North American Neuro-Ophthalmology Society |
| ARK | ark:/87278/s67gaq23 |
| Setname | ehsl_novel_jno |
| ID | 2498906 |
| Reference URL | https://collections.lib.utah.edu/ark:/87278/s67gaq23 |