| Title |
Leber Hereditary Optic Neuropathy in a Mother and Daughter Associated With m.10197G>A Mutation |
| Creator |
Omar Solyman; Peter MacIntosh |
| Affiliation |
Department of Ophthalmology, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL |
| Abstract |
We read with great interest the letter by Jorstad et al (1) describing a 16-year-old boy with Leber hereditary optic neuropathy (LHON) harboring a mitochondrial DNA 10663T>C point mutation and his favorable response to idebenone treatment. We also recently encountered a patient with LHON who had an unusual mitochondrial DNA mutation and experienced marked improvement with idebenone. |
| Subject |
Consensus; DNA, Mitochondrial; Female; Humans; Mothers; Mutation; Nuclear Family; Optic Atrophy, Hereditary, Leber |
| Date |
2019-03 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Publication Type |
Journal Article |
| Source |
Journal of Neuro-Ophthalmology, March 2019, Volume 39, Issue 1 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| ARK |
ark:/87278/s6x69bgs |
| Setname |
ehsl_novel_jno |
| ID |
1595913 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6x69bgs |
