Comparing the Classic 2 Repetitions Per Second (2RPS) Visually Evoked Potential (VEP) with a New Metric using the Standard 60-Second Arc Check Size Driven by a Binary M-Sequence in a Group of Multiple Sclerosis Patients and Controls

Newer display technologies like liquid-crystal-on-silicon (LCOS) are rapidly supplanting the antiquated CRT methods, mandating a critical analysis of the altered VEP responses. Newer stimulators optimized for multi-focal stimulation currently only generate qualitative results. Additionally these newer stimulators can be tightly calibrated allowing for multicenter studies. Utilizing the binary m-sequence which when applied to a conventional standard checkerboard VEP allows for a new test with shorter testing times, higher signal-to-noise ratios and a single quantitative result. We aim to compare the classic 2 repetitions-per-second (2RPS) visually evoked potential (VEP) with a newer conventional VEP test using the standard 60-second arc check-size generated by a binary m-sequence to test its viability and specificity in a group of multiple sclerosis (MS) patients and controls.