Excavation of the optic nerve: a characteristic form of the evolution towards optic atrophy in methanol poisoning

Methanol is an industrial-use product. Methanol ingestion may be accidental, with suicidal intent or as a substitute for ethyl alcohol when it is not affordable. After methanol poisoning it has been observed a permanent loss of vision in 11-18 % of patients. Other neurological abnormalities caused by methanol include: confusion, coma and putaminal necrosis. Optic atrophy after methanol exposure is evident within 30-60 days. In some patients without knowing exactly why atrophy occurs mimicking glaucomatous cupping.