| Identifier |
walsh_2001_s2_c4 |
| Title |
Discs are Swollen |
| Creator |
Byron L. Lam, MD; Janet Davis, MD |
| Affiliation |
(BLL) (JD) Miami, FL |
| Subject |
Paraneoplastic Polyneuropathy; Papilledema; Carcinoma, Small Cell; Lung Neoplasms; Optic Neuritis; Autoimmune Diseases |
| History |
A 72-year old male with a 4-month history of painless, progressive loss of vision and transient visual obscurations OU. |
| Pathology |
Circulating anti-CV2 antibodies associated with small cell carcinoma of the lung |
| Disease/Diagnosis |
Bilateral paraneoplastic optic neuropathy due to CV2-autoantibodies associated with small cell lung cancer |
| Clinical |
VA: Best corrected, 20/200 OU; Color plates: 5/15 OD, 8/15 OS; Optic nerve heads demonstrated diffuse edema |
| Presenting Symptom |
Visual loss with transient visual obscurations OU |
| Neuroimaging |
N/A |
| Treatment |
Antineoplastic agents; XRT |
| Date |
2001 |
| References |
1. de la Sayette V, Bertran F, Honnorat J, Schaeffer S, Iglesias S, Defer G. Paraneoplastic cerebellar syndrome and optic neuritis with anti-CV2 antibodies: clinical response to excision of the primary tumor. Arch Neurol 1998;55:405-408. 2. Honnorat J, Aguera M, Zale B, Goujet C, Quach T, Antoine JC, Belin MF. POP66, a paraneoplastic encephalomyelitis-related antigen is a marker of adult oligodendrocytes. J Neuropath Exp Neurol 1998;57:311-322. 3. Honnorat J, Byk T, Kusters I, Aguera M, Ricard D, Rogemond V, Quach T, Aunis D, Sobel A, Mattei MG, Kalattukudy P, Belin MF, Antoine JC. Ulip4/CRMP3 proteins are recognized by autoantibodies in paraneoplastic neurological syndromes. Euro J Neuroscie 1999;11:4226-4232. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
27th Annual North American Neuro-Ophthalmology Society Meeting, Frank B. Walsh Session CD-ROM |
| Relation is Part of |
NANOS Annual Meeting 2001 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6x92f04 |
| Setname |
ehsl_novel_fbw |
| ID |
177711 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6x92f04 |
