National Neuroscience Institute, Singapore, Singapore
Subject
Demyelinating Peripheral Neuropathy; Miller Fisher Syndrome; Guillain-Barré Syndrome; CANOMAD
Description
The elucidation of immunoPathology at the nodal and paranodal regions of peripheral nerves, so called nodopathy-paranodopathy, is likely to open up new avenues of investigation into other immunological diseases linked to similar antibodies. Examples include autoimmune limbic encephalitis and epilepsy (both associated with leucine-rich glioma inactivated 1protein, LGI1, of the voltage-gated potassium channel complex, VGKC), Morvan's syndrome (associated with Caspr2 antibody), Isaacs' syndromeneuromyotonia (associated with VGKC antibody), Bickerstaff encephalitis (associated with GQ1b antibody) and CANOMAD (chronic, ataxia, neuropathy, ophthalmoplegia, M protein, agglutination, and associated with disialosyl GD1b ganglioside antibodies). Neuro-ophthalmologists may well encounter these conditions so it is helpful to have some familiarity with them.
Date
2019-03
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
2019 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of
NANOS Annual Meeting 2019: New Information I Should Know
