Are Video-oculography Findings Linked to Specific Clinical Features in Parkinson's Disease?

Ocular findings are useful in differentiating some neurodegenerative disorders. In contrast, there were no disease-specific ocular findings which favor Parkinson's disease (PD), although saccadic hypometria, frequent square wave jerks (SWJs), and impaired antisaccade and/or impaired smooth pursuit have been relatively often reported in PD compared to normal controls. Additionally, there was no well-performed study for the correlation between abnormal ocular signs for brainstem-cerebellar involvement (AOS-BCs) [perverted head-shaking nystagmus, positional downbeat-nystagmus, gaze-evoked nystagmus, and hypermetria], which could be found in part of PD patients. We studies which specific clinical features are correlated with SWJs and AOS-BCs to evaluate their clinical significances in PD.