Lipocalin-2 Expression in Demyelinating Optic Neuritis of Experimental Autoimmune Encephalomyelitis Model and their Pivotal Role

Identifier 20150223_nanos_sciplatform1_01
Title Lipocalin-2 Expression in Demyelinating Optic Neuritis of Experimental Autoimmune Encephalomyelitis Model and their Pivotal Role
Creator Bo Young Chun; Jong-Heon Kim; Youngpyo Nam; Seungwoo Han; Kyoungho Suk
Affiliation (BYC) Department of Ophthalmology, Kyungpook National University Hospital, Daegu, Korea; (JK) (YN) (KS) Department of Pharmacology, Brain science and engineering institute, Kyungpook National University School of Medicine, Daegu, Korea; (SH) Division of Rheumatology, Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea
Subject Experimental Autoimmune Optic Neuritis; Lipocalin 2; Demyelination; Reactive Astrocytosis; Microglial Activation
Description Introduction: The purpose of this study is to determine the role of lipocalin 2 (LCN2) in experimental autoimmune optic neuritis (EAON) model. We compared degrees of neuro-inflammation between LCN2 knock out (KO) mice and wild type (WT) littermates by histological analysis of demyelination, reactive astrocytosis and proliferation of microglia.
Date 2015-02-23
Language eng
Format application/pdf
Type Text
Source 2015 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2015 Platform Session 1
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2015. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6671m0m
Setname ehsl_novel_nam
ID 184687
Reference URL https://collections.lib.utah.edu/ark:/87278/s6671m0m