| Identifier |
walsh_2009_s4_c2 |
| Title |
Hear No Evil, See No Evil (Audio) |
| Creator |
Sashank Prasad; Brian Callaghan; Steven Galetta |
| Subject |
Mitochondrial Encephalomyopathies; MELAS Syndrome; Point Mutation; Hearing Loss, Sensorineural; Scotoma; Pupil Disorders; Optic Neuritis |
| History |
A 62-year old female with painless loss of vision OS. Previous history significant for bilateral sensorineural deafness. |
| Pathology |
Retinal nerve fiber atrophy; Axonal polyneuropathy; Inherited mitochondrial disorder |
| Disease/Diagnosis |
MELAS Syndrome |
| Clinical |
VA: 20/20 OD, 20/200 OS; Color plates: 8/11 OD, 0/11 OS; RAPD OS |
| Presenting Symptom |
Painless loss of vision OS |
| Neuroimaging |
MRI |
| Treatment |
N/A |
| Date |
2009-02 |
| References |
1. Dickerson, Holtzman, Grant, Tian. Case records of the Massachusetts General Hospital. Case 36-2005. A 61-year-old woman with seizure, disturbed gait, and altered mental status. N Engl J Med 353, 2271-2280, 2005. 2. Mizrachi, Gomez-Hassan, Blaivas, Trobe. Pitfalls in the diagnosis of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes. J Neuroophthalmol, 26, 38-43, 2006. 3. Apostolova, White, Moore, et al. Deep white matter pathologic features in watershed regions. A novel pattern of central nervous system involvement in MELAS. Arch Neurol 62, 1 1 54-6, 2005. 4. Goto, Nonaka, Horai. A mutation in the tRNA(Leu) (UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature, 348, 651-653, 1990. 5. Scaglia, Northrop. The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options. CNS Drugs 20, 443-464, 2006. |
| Language |
eng |
| Format |
audio/mpeg |
| Type |
Sound |
| Source |
41st Annual Frank Walsh Society Meeting |
| Relation is Part of |
NANOS Annual Meeting 2009 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2009. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s66q2134 |
| Setname |
ehsl_novel_fbw |
| ID |
179071 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s66q2134 |
