| Identifier |
walsh_2009_s1_c1 |
| Title |
Progressive Visual Loss in a Man with Leukemia |
| Creator |
Michael Lee Karen SantaCruz; Jeffrey Brace; Alexander Mckinney |
| Affiliation |
University of Minnesota, Minneapolis, MN |
| Subject |
Bone Marrow Transplantation; Myeloablative Agonists; Blindness, Cortical; Neurotoxicity Syndromes; Leukemia, Myeloid, Acute; Demyelinating Diseases |
| History |
A 48-year old male diagnosed with acute myeloid leukemia: Tx BMT. |
| Pathology |
White matter vacuolization, axonal spheroids, macrophages in medulla and spinal cord. |
| Disease/Diagnosis |
Neurotoxicity secondary to fludarabine administration |
| Clinical |
VA: Light perception OD, Hand motions OS |
| Presenting Symptom |
Blurred vision OS |
| Neuroimaging |
MRI |
| Treatment |
Myeloablative agonists |
| Date |
2009-02 |
| References |
1. Ding X, Herzligh AA, et al. Ocular toxicity of fludarabine: a purine analog. Expert Rev Ophthalmol. 2008;3:97-109. 2. Chun HG, Leyland-Jones, BR, et al. Central nervous system toxicity of fludarabine phosphate. Cancer Treat Rep. 1986;70:1225-28. 3. Warrell RP, Berman E. Phase I and II study of fludarabine phosphate in leukemia: therapeutic efficacy with delayed central nervous system toxicity. J Clin Oncol. 1986;4:74-79. 4. Cheson BD, Vena DA, et al. Neurotoxicity of purine analogs: a review. J Clin Oncol 1 994; 12:2216-28. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
41st Annual Frank Walsh Society Meeting |
| Relation is Part of |
NANOS Annual Meeting 2009 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2002. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s65m68j1 |
| Setname |
ehsl_novel_fbw |
| ID |
178723 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s65m68j1 |
