Walsh & Hoyt: Mycosis Fungoides (Cutaneous T-Cell Lymphoma)

Mycosis fungoides is a malignant lymphoma that arises in the skin. It is derived from T-lymphocytes, in contrast to the vast majority of systemic lymphomas that are of B-cell origin. Three stages in the course of the disease can usually be distinguished: eczematous, infiltrative, and tumor. Although originally considered a malignancy of the skin, the late stages of the disease may affect the organs of the abdomen and chest, the CNS, and the eye.