| Identifier | 20230314_nanos_sciplatform3_06 |
| Title | Characterization of Subclinical Optic Nerve MRI Lesions in the N-Momentum Trial |
| Creator | Jeffrey Bennett; Friedemann Paul; John Chen; Michael Smith; Daniel Cimbora; Kristina Patterson; Bruce Cree |
| Affiliation | (JB) University of Colorado Anschutz Medical Campus; (FP) Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecular Medicine in the Helmholtz Association and Charité Universitätsmedizin Berlin, Germany, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin; (JC) Mayo Clinic; (MS) (DC) (KP) Horizon Therapeutics plc; (BC) University of California San Francisco |
| Subject | Optic Neuritis; Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid) |
| Description | Neuromyelitis optica spectrum disorder (NMOSD) causes inflammatory attacks on the optic nerves (ON), spinal cord, and brain. The N-Momentum trial of inebilizumab for NMOSD prospectively collected MRI data. Previously-reported subclinical MRI findings are of unknown significance.1,2 Here, we evaluate the frequency, prognosis, and response to inebilizumab of asymptomatic (subclinical) ON MRI lesions. |
| Date | 2023-03 |
| References | 1. Paul F et al; Quiescent MRI activity in NMOSD: results from the N-MOmentum randomized placebo- controlled trial. Presented at ECTRIMS 2020 Annual Congress. 2. Shah S, et al; Frequency of Asymptomatic Optic Nerve Enhancement in a Large Retrospective Cohort of Patients With Aquaporin-4+ NMOSD. Neurology. 13;99(8):e851-e857, 2022 |
| Language | eng |
| Format | video/mp4 |
| Type | Image/MovingImage |
| Source | 2023 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of | NANOS Annual Meeting 2023: Scientific Platform Session III: https://novel.utah.edu/collection/NAM/toc/ |
| Collection | Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher | North American Neuro-Ophthalmology Society |
| Holding Institution | Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management | Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK | ark:/87278/s6jz4y21 |
| Setname | ehsl_novel_nam |
| ID | 2385994 |
| Reference URL | https://collections.lib.utah.edu/ark:/87278/s6jz4y21 |