Infliximab-Induced Optic Perineuritis and Facial Myositis

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Title Infliximab-Induced Optic Perineuritis and Facial Myositis
Creator Loulwah Mukharesh; Amanda Tinsley
Affiliation Department of Neuro-Ophthalmology (LM), Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA; and Department of Neurology (LM, AT), George Washington University, Washington, DC
Abstract Optic neuritis is an inflammatory condition involving the optic nerve with autoimmune, demyelinating, toxic or infectious etiologies. Myositis is a rare but reported complication of infliximab (1), whereas the incidence of infliximab-induced optic neuritis is far more common than infliximab-induced myositis (1), occurring in approximately 10.4 per 100,000 person-years in a retrospective population-based cohort study (2).
Subject Infliximab; Myositis; Optic Neuritis; Vision Disorders
OCR Text Show
Date 2022-12
Date Digital 2022-12
References 1. Zhou Y, Lower EE, Li H, Baughman RP. Sarcoidosis patient with lupus pernio and infliximab-induced myositis: response to Acthar gel. Respir Med Case Rep. 2016;17:5-7. 2. Winthrop KL, Chen L, Fraunfelder FW, Ku JH, Varley CD, Suhler E, Hills WL, Gattey D, Baddley JW, Liu L, Grijalva CG, Delzell E, Beukelman T, Patkar NM, Xie F, Herrinton LJ, Fraunfelder FT, Saag KG, Lewis JD, Solomon DH, Curtis JR. Initiation of anti-TNF therapy and the risk of optic neuritis: from the safety assessment of biologic ThERapy (SABER) Study. Am J Ophthalmol. 2013;155:183-189.e1. 3. Solomon AJ, Spain RI, Kruer MC, Bourdette D. Inflammatory neurological disease in patients treated with tumor necrosis factor alpha inhibitors. Mult Scler. 2011;17:1472-8787. 4. ALGaeed M, Mukharesh L, Heinzelmann M, Kaminski HJ. Pearls & Oy-sters: pembrolizumab-induced myasthenia gravis. Neurology. 2018;91:e1365-e1367. 5. Mukharesh L, Chwalisz BK. Neuro-ophthalmic complications of checkpoint inhibitors. Semin Ophthalmol. 2021;36:241-249.
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, December 2022, Volume 42, Issue 4
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6h7qryw
Setname ehsl_novel_jno
ID 2392974
Reference URL https://collections.lib.utah.edu/ark:/87278/s6h7qryw
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