| Title |
Interocular Difference in Retinal Nerve Fiber Layer Thickness Predicts Optic Neuritis in Pediatric-Onset Multiple Sclerosis |
| Creator |
Amy T. Waldman, MD, MSCE; Leslie Benson, MD; John R. Sollee, BS; Amy M. Lavery, PhD; Geraldine W. Liu, ALM; Ari J. Green, MD, MCR; Emmanuelle Waubant, MD; Gena Heidary, MD, PhD; Darrel Conger, CRA; Jennifer Graves, MD, PhD; Benjamin Greenberg, MD, MHS |
| Affiliation |
Division of Neurology (ATW, JRS, AML, GWL), Children's Hospital of Philadelphia and Departments of Neurology and Pediatrics (ATW), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Departments of Neurology (LB) and Ophthal- mology (GH), Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts; Division of Neuroimmunology and Glial Biology (AJG, EW), Department of Neurology, Weill Institute of Neurosciences, University of California San Francisco, San Francisco, Cal- ifornia; Department of Neurology and Neurotherapeutics (DC, BG), University of Texas Southwestern Medical Center, Dallas, Texas; Department of Neurology, University of California San Diego, San Diego, California; and Department of Ophthalmology (AJG), University of California San Francisco, San Francisco, California |
| Abstract |
Optical coherence tomography (OCT) is capa- ble of quantifying retinal damage. Defining the extent of anterior visual pathway injury is important in multiple sclerosis (MS) as a way to document evidence of prior disease, including subclinical injury, and setting a baseline for patients early in the course of disease. Retinal nerve fiber layer (RNFL) thickness is typically classified as low if values fall outside of a predefined range for a healthy population. In adults, an interocular difference (IOD) in RNFL thickness greater than 5 mm identified a history of unilateral optic neuritis (ON). |
| Subject |
OCT; Multiple Sclerosis; PERCEPTION |
| Date |
2021-12 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Publication Type |
Journal Article |
| Source |
Journal of Neuro-Ophthalmology, December 2021, Volume 41, Issue 4 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| ARK |
ark:/87278/s67m5e65 |
| Setname |
ehsl_novel_jno |
| ID |
2116240 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s67m5e65 |
