Binocular Visual Function Testing in an Alzheimer's Disease Research Center (ADRC) Cohort: Low-Contrast Letter Acuity and Rapid Automatized Naming (RAN) Tasks of MULES and SUN

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Identifier 20240305_nanos_sciplatform3_03
Title Binocular Visual Function Testing in an Alzheimer's Disease Research Center (ADRC) Cohort: Low-Contrast Letter Acuity and Rapid Automatized Naming (RAN) Tasks of MULES and SUN
Creator Lauren Seidman; Sara Hyman; Steven Galetta; Arjun Masurkar; Laura Balcer
Affiliation (LS) (SH) (SG) (AM) (LB) NYU Grossman School of Medicine
Subject Higher Visual Functions; Neuro-ophth & Systemic Disease ( eg. MS, MG, thyroid); Diagnostic Tests (ERG, VER, OCT, HRT, mfERG, etc); Eyelid & Adnexal Disease
Description Binocular vision testing, performed with both eyes uncovered, is useful for reflecting daily activities. Low-contrast letter acuity (LCLA), the Mobile Universal Lexicon Evaluation System (MULES, rapid picture naming) and the Staggered Uneven Number (SUN, rapid number naming) have been used successfully in studies of multiple sclerosis, concussion and Parkinson's disease. We determined the capacity for LCLA, MULES and SUN, to distinguish patients with mild cognitive impairment (MCI) due to Alzheimer's disease and Alzheimer's dementia (AD) vs. cognitively normal controls.
Date 2024-03
References Park G, Balcer MJ, Colombo JR, Hasanaj L, Joseph B, et al.; The MICK (Mobile Integrated Cognitive Kit) App: Digital rapid automatized naming for visual assessment across the spectrum of neurological disorders, J Neurol Sci, 434, 120150, 2022. Dahan N, Moehringer N, Hasanaj L, Serrano L, Joseph B, et al.; The SUN test of vision: Investigation in healthy volunteers in comparison to the Mobile Universal Lexicon Evaluation System (MULES), J Neurol Sci, 415, 116953, 2020. Conway J, Ilardi M, Gonzalez C, Dahan N, Fallon S, et al.; Rapid picture naming in Parkinson's disease using the Mobile Universal Lexicon Evaluation System (MULES), J Neurol Sci, 410, 116953, 2020. Balcer LJ, Raynowska J, Nolan R, Galetta SL, Kapoor R, et al.; Validity of low-contrast letter acuity as a visual performance outcome measure for multiple sclerosis, Mult Scler 23, 734-747, 2017. Balcer LJ, Galetta SL, Calabresi PA, Confavreux C, Giovannoni G, et al.; Natalizumab reduces visual loss in patients with relapsing multiple sclerosis, Neurology, 68, 1299-1304, 2007.
Language eng
Format video/mp4
Type Image/MovingImage
Source 2024 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2024: Scientific Platform: Session III
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2024. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6vh2b8h
Setname ehsl_novel_nam
ID 2589956
Reference URL https://collections.lib.utah.edu/ark:/87278/s6vh2b8h
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