Clinical Activity and Safety of VRDN-001, a Full Antagonist Antibody to Insulin-like Growth Factor-1 Receptor, in Active and Chronic Thyroid Eye Disease

Update Item Information
Identifier 20240305_nanos_sciplatform3_02
Title Clinical Activity and Safety of VRDN-001, a Full Antagonist Antibody to Insulin-like Growth Factor-1 Receptor, in Active and Chronic Thyroid Eye Disease
Creator Kimberly Cockerham; Roger Turbin; Michael Yen; Navdeep Nijhawan; Jody Abrams; Andrea Kossler; Rosa Tang; Chantal Boisvert; David Kaufman; Wendy Lee; Raghu Mudumbai; Madhura Tamhankar; Michael Yoon; Shoaib Ugradar; Cathy Michalsky; Barrett Katz
Affiliation (KC) Senta Clinic, San Diego, CA; (RT) Rutgers New Jersey Medical School, Newark, NJ; (MY) Baylor College of Medicine, Alkek Eye Center, Houston, TX; (NN) Oshawa Clinic, Oshawa, ON, Canada; (JA) Sarasota Retina Institute, Sarasota, FL; (AK) Stanford University Department of Ophthalmology at Byers Eye Institute, Palo Alto, CA; (RT) Eye Wellness Center-Neuro-Eye Clinical Trials, Inc., Bellaire, TX; (CB) University of Vermont Medical Center; (DK) Department of Neurology and Ophthalmology, Michigan State University; (WL) Bascom Palmer Eye Institute, Miami, FL; (RM) UW Medicine, Seattle, WA; (MT) Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA; (MY) Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA; (SU) The UCLA Stein Eye Institute, Los Angeles, CA; (CM) (BK) Viridian Therapeutics, Waltham, MA
Subject Graves' Disease; Neuro-ophth & Systemic Disease ( eg. MS, MG, thyroid); Orbit/ocular Pathology
Description Clinical activity and safety of 2 infusions of VRDN-001 were tested in both active thyroid eye disease (TED) and longer-persisting, more refractory chronic TED in phase 2 proof-of-concept studies.
Date 2024-03
References None provided.
Language eng
Format video/mp4
Type Image/MovingImage
Source 2024 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2024: Scientific Platform: Session III
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2024. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s626wb8h
Setname ehsl_novel_nam
ID 2589955
Reference URL https://collections.lib.utah.edu/ark:/87278/s626wb8h
Back to Search Results