| Identifier |
walsh_2015_s1_c1 |
| Title |
Some Like it Hot |
| Creator |
Ahmara G. Ross; Islam Zaydan; Gabrielle Bonhomme; Ellen Mitchell; Tarek Shazly; Deborah Parrish |
| Affiliation |
(AGR) (TS) (DP) UPMC/ University of Pittsburgh Department of Ophthalmology Pittsburgh, PA; (IZ) UPMC/University of Pittsburgh Department of Neurology Pittsburgh, PA; (IZ) (GB) (EM) (TS) UPMC/ University of Pittsburgh Department of Neuro-Ophthalmology Pittsburgh, PA |
| Subject |
Diplopia, Ocular Motor Nerve Palsy, Cranial Nerve Palsies, Post-Transplant Lymphoproliferative Disorder |
| Description |
Findings were concerning for Myasthenia Gravis, Recurrent Melanoma, Lymphoma, or a Post-transplant Lymphoproliferative Disorder (PTLD). EMG showed findings suggestive of chronic lumbosacral radiculopathies superimposed on a mild sensorimotor polyneuropathy, but a normal functioning neuromuscular junction. Repeat MRI of the brain and orbits showed abnormal enhancement of the right anterior clinoid process with soft tissue extending into the right orbital apex, adjacent superior right sphenoid sinus as well as the anterolateral right cavernous sinus. Bone scan showed increased uptake in the right humeral head extending into the proximal humerus with a focal, circular region of uptake in right posterior parieto-occipital skull. |
| History |
A 71 year old Caucasian man with a past medical history of hypertension, hyperlipidemia, Type 2 DM, ESRD status post renal transplant, facial melanoma, currently on ASA for a stable left sided putaminal hemorrhage presented with new right sided ptosis and lower extremity weakness. Brain MRI obtained on admission showed small cortical hemorrhages consistent with prior stroke, without evidence of acute pathologic changes. Repeat fine cut MRI of the brain and orbits with and without contrast showed an enhancing lesion in the right parietal bone, clinoid process, and associated abnormal soft tissue changes extending into the right orbital apex, adjacent superior right sphenoid sinus, and the right anterolateral cavernous sinus. |
| Disease/Diagnosis |
Infiltrative Right Cranial Nerve Palsy secondary to Post Transplant Lymphoproliferative Disorder |
| Date |
2015-02 |
| References |
1. Taylor, A.L., R. Marcus, and J.A. Bradley, Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation. Crit Rev Oncol Hematol, 2005. 56(1): p. 155-67. 2. Lim, W.H., G.R. Russ, and P.T. Coates, Review of Epstein-Barr virus and post-transplant lymphoproliferative disorder post-solid organ transplantation. Nephrology (Carlton), 2006. 11(4): p. 355-66. |
| Language |
eng |
| Format |
video/mp4 |
| Type |
Image/MovingImage |
| Source |
47th Annual Frank Walsh Society Meeting |
| Relation is Part of |
NANOS Annual Meeting 2015 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2015. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6hf0s8r |
| Setname |
ehsl_novel_fbw |
| ID |
179271 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6hf0s8r |
