| Identifier |
walsh_2011_s2_c4 |
| Title |
A Case of Net Visual Loss and Gain (Presentation Video) |
| Creator |
Thomas Slamovits; Jerome Posner; Diane Reidy; Charles Thirkill; John Keltner |
| Affiliation |
(TS) Albert Einstein College of Medicine, Department of Ophthalmology, Neurology and Neurosurgery, Bronx, NY; (JP) Memorial Sloan-Kettering Cancer Center, Department of Neurology, New York, NY; (DR) Memorial Sloan-Kettering Cancer Center, Department of Medicine, New York, NY; (CT) Ocular Immunology Laboratory, University of California Davis, Department of Ophthalmology and Vision Science, Davis, CA; (JK) University of California Davis Medical Center, Department of Ophthalmology and Vision Science, Neurology and Neurosurgery, Sacramento, CA |
| Subject |
Optic Nerve Diseases; Ocular Paraneoplastic Syndromes; Neuroendocrine Tumors; Pancreatic Neoplasms; Neoplasm Metastasis |
| History |
A 68-year old female with a sudden loss of vision OU. Previous history significant for anemia, presumed by patient to account for her presenting symptoms. |
| Pathology |
Multiple rim-enhancing hepatic lesions of parenchymal prominence in the tail of the pancreas. |
| Disease/Diagnosis |
Paraneoplastic optic neuropathy secondary to non-secretory pancreatic (islet cell) neuroendocrine tumor |
| Clinical |
VA: (best-corrected) 20/125 OD - improvable with pinhole to 20/100 OD, 20/100 OS |
| Presenting Symptom |
Sudden bilateral loss of vision; RAPD OS |
| Neuroimaging |
MRI |
| Treatment |
IVIG; Antineoplastic agents |
| Date |
2011-02 |
| References |
1. Boghen, D., M. Sebag, and J. Michaud, Paraneoplastic optic neuritis and encephalomyelitis. Report o f a case. Arch Neurol, 1988. 45(3): p. 353-6. 2. Margolin, E, Flint A and Trobe, JD High-Titer Collapsin Response -Mediating Protein-Associated (CRMP-5) Paraneoplastic Optic Neuropathy and Vitritis as the Only Clinical Manifestations in a Patient With Small Cell Lung Carcinoma J Neuro-Ophthalmol 2008, 28: 17-22. 3. Cross SA, Salomao DR, Parisi JE, et al. Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG. Ann Neurol 2003; 54:38-50. 4. Ares-Luque A, Garcia-Tunon LA, Saiz A, et al. Isolated paraneoplastic optic neuropathy associated with smallcell lung cancer and anti-CV2 antibodies. J Neurol 2007; 254:1131-2. 5. Calvert PC. A CR(I)MP in the optic nerve: recognition and implications of paraneoplastic optic neuropathy. J Neuroophthalmol 2006; 26:165-7. |
| Language |
eng |
| Format |
video/mp4 |
| Type |
Image/MovingImage |
| Source |
43rd Annual Frank Walsh Society Meeting |
| Relation is Part of |
NANOS Annual Meeting 2011 |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2011. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6251n20 |
| Setname |
ehsl_novel_fbw |
| ID |
179049 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6251n20 |
