In Vivo Evaluation of Drugs Used to Treat Idiopathic Intracranial Hypertension
Creator
James Mitchell; William Scotton; Hannah Botfield; Connar Westgate; Andreas Yiangou; Maria Uldall; Rigmor Jensen; Alex Sinclair
Affiliation
(JM) (WS) (HB) (CW) (AS) Institue of Metabolism and Systems Research University of Birmingham, Birmingham, United Kingdom; (AY) Institute of Metabolism and Systems Research, Edgbaston, Birmingham, United Kingdom; (MU) (RJ) Danish Headache Centre, Rigshospitalet-Glostrup, University of Copenhagen, Glostrup, Denmark
Subject
High Intracranial Pressure; Headache; Pseudotumor Cerebri
Description
The management of idiopathic intracranial hypertension (IIH) is focused on reducing ICP to try to both preserve visual function, as well as reduce chronic headaches. There is sparse evidence to support the use of some of the drugs commonly used to manage IIH, therefore we propose to evaluate the efficacy of acetazolamide, topiramate, furosemide, amiloride and octreotide at lowering ICP in healthy rats.
Date
2018-04
Language
eng
Format
video/mp4
Type
Image/MovingImage
Source
2018 North American Neuro-Ophthalmology Society Annual Meeting