Idiopathic Intracranial Hypertension: Relation Between Obesity and Visual Outcomes

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Title Idiopathic Intracranial Hypertension: Relation Between Obesity and Visual Outcomes
Creator Aimee J. Szewka, MD; Beau B. Bruce, MD; Nancy J. Newman, MD; Valérie Biousse, MD
Affiliation Departments of Ophthalmology, Neurology, and Neurological Surgery, Emory University School of Medicine, Atlanta, Georgia
Abstract Increased body mass index (BMI) has been associated with increased risk of idiopathic intracranial hypertension (IIH), but the relationship of BMI to visual outcomes in IIH is unclear. A retrospective chart review of all adult cases of IIH satisfying the modified Dandy criteria seen at our institution between 1989 and 2010 was performed. Demographics, diagnostic evaluations, baseline visit and last follow-up examination data, treatment, and visual outcome data were collected in a standardized fashion. Groups were compared, and logistic regression was used to evaluate the relationship of BMI to severe visual loss, evaluating for interaction and controlling for potential confounders. Among 414 consecutive IIH patients, 158 had BMI $40 (World Health Organization Obese Class III) and 172 had BMI 30-39.9. Patients with BMI $40 were more likely to have severe papilledema at first neuroophthalmology encounter than those with a lower BMI (P = 0.02). There was a trend toward more severe visual loss in 1 or both eyes a last follow-up among those patients with BMI $40 (18% vs 11%, P = 0.067). Logistic regression odeling found that 10-unit (kilogram per square meter) increases in BMI increased the odds of severe visual loss by 1.4 times (95% confidence interval, 1.03-1.91, P = 0.03) after controlling for sex, race, diagnosed hypertension, and diagnosed sleep apnea. Our finding of a trend for severe papilledema and visual loss associated with increasing BMI suggests.
Subject Adolescent; Adult; Older people; Body Mass Index; Female; Humans; Male; Middle Older people; Obesity; Papilledema; Pseudotumor Cerebri; Retrospective Studies; Risk Factors; Treatment Outcome; Vision Disorders; Visual Acuity
OCR Text Show
Date 2013-03
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6np59g6
Setname ehsl_novel_jno
ID 227369
Reference URL https://collections.lib.utah.edu/ark:/87278/s6np59g6
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