Venous Sinus Stenting in Idiopathic Intracranial Hypertension: Results of a Prospective Trial.

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Title Venous Sinus Stenting in Idiopathic Intracranial Hypertension: Results of a Prospective Trial.
Creator Dinkin, Marc J, Patsalides, Athos
Affiliation Department of Ophthalmology (MJD), New York Presbyterian Hospital, Weill Cornell Medical College, New York, New York Division of Interventional Neuroradiology, Department of Neurological Surgery (AP), New York Presbyterian Hospital, Weill Cornell Medical College, New York, New York.
Abstract Transient monocular vision loss (TMVL) is an alarming symptom owing to potentially serious etiologies such as thromboembolism or giant cell arteritis. Our objective is to describe the phenomenon of TMVL present on awakening, which may represent a distinct and benign entity. We performed a retrospective observational case series of 29 patients who experienced TMVL on awakening. Patients who described monocular dimming or blackout of vision were included, and those with blurred vision, concurrent eye pain, and binocular vision loss were excluded. Descriptive statistics were used to summarize the study population. Of the 29 patients we studied, 90% (n = 26) were female and 48% had crowded discs (cup-to-disc ratio ≤0.2). The mean age was 45.4 years, although women were significantly younger than men (mean ages 43.4 and 62.7 years, respectively, P = 0.017). Brain magnetic resonance imaging and vascular imaging (magnetic resonance angiography, computed tomographic angiography, or carotid Doppler) were performed in 69% and 55% of cases, respectively, and were uniformly negative. In 14 patients for whom clear follow-up data could be obtained, no medically or visually significant sequelae of this syndrome were found, and 50% experienced resolution of symptoms. Evaluation was uniformly negative when patients described waking with isolated vision loss in 1 eye with subsequent resolution, usually in less than 15 minutes. The natural history seems benign with symptoms frequently remitting spontaneously. This visual phenomenon may represent an autoregulatory failure resulting in a supply/demand mismatch during low-light conditions.
Subject Female; Male; Neural Inhibition; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Long-Evans; Synaptic Transmission
OCR Text Show
Date 2017-06
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6pg5zbh
Setname ehsl_novel_jno
ID 1364477
Reference URL https://collections.lib.utah.edu/ark:/87278/s6pg5zbh
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