Validation and application of a novel high density electrode array for use in small diameter peripheral nerves

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Title Validation and application of a novel high density electrode array for use in small diameter peripheral nerves
Publication Type thesis
School or College College of Engineering
Department Biomedical Engineering
Author Mathews, Kiran Serah
Date 2017
Description Several neural interfaces have been designed in order to improve access to peripheral nerve fibers and more accurately monitor or evoke various functions. Currently, such devices are more successful in larger nerves, but are limited in potential applications involving smaller target nerves. For example, the restoration of micturition (urination) to spinal cord injured patients requires the ability to monitor the changes in bladder pressure, to gauge bladder fullness as well as detect hyper-reflexive contractions. The pudendal nerve has been shown to be an appropriate site for monitoring bladder status. However, its small diameter, particularly in animal models, and the need for multiple access points required the development and fabrication of a novel high density electrode array. The research presented here describes the validation of such a device in small diameter nerve applications, as well as its use in the pudendal nerve to provide information about bladder pressure, showing the potential expansion of neural interfaces to new applications in both research and clinical fields.
Type Text
Publisher University of Utah
Subject Bioengineering; Neurosciences
Dissertation Name Master of Science
Language eng
Rights Management (c) Kiran Serah Mathews
Format application/pdf
Format Medium application/pdf
ARK ark:/87278/s6gj4037
Setname ir_etd
ID 1424036
Reference URL https://collections.lib.utah.edu/ark:/87278/s6gj4037
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