Tachyphylaxis With Sustained Apraclonidine Use in the Treatment of Ptosis Associated With Horner Syndrome

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Identifier 20220213_nanos_posters_211
Title Tachyphylaxis With Sustained Apraclonidine Use in the Treatment of Ptosis Associated With Horner Syndrome
Creator Jessica Kraker; Deena Tajfirouz; M. Tariq Bhatti; John Chen
Affiliation (JK) (DT) (MTB) (JC) Mayo Clinic, Rochester, Minnesota
Subject Pupil; Miscellaneous; Neuroimaging; Eyelid & Adnexal Disease
Description Apraclonidine is an adrenergic agonist with stronger affinity for α2 receptors than α1 receptors. Following sympathetic denervation in Horner syndrome, α receptors are upregulated, and therefore apraclonidine causes both mydriasis, via the effect of α1 stimulation of the dilator pupillae, and lid elevation, via the effect of α2 stimulation on Müller's muscle. In addition to being helpful in confirming Horner syndrome, apraclonidine can be used as a therapeutic agent for ptosis.
Date 2022-02
Language eng
Format application/pdf
Type Text
Source 2022 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2022: Poster Session I: Pupillary Disorders
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2022. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6htkxgj
Setname ehsl_novel_nam
ID 2063405
Reference URL https://collections.lib.utah.edu/ark:/87278/s6htkxgj
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