Identifier |
wh_ch37_p1759 |
Title |
Walsh & Hoyt: Chemotherapy |
Creator |
Mark L. Moster, MD; Rod Foroozan, MD |
Affiliation |
(MLM) Thomas Jefferson University; (RF) Baylor College of Medicine |
Subject |
Neoplasms; Neoplasms, Therapy; Chemotherapy, Adverse Effects; Radiotherapy, Adverse Effects; Bone Marrow Transplantation, Adverse Effects; Complications of Cancers; Neuro-ophthalmic Complications of Chemotherapy |
Description |
Most chemotherapeutic medications act on rapidly dividing tumor cells. Because the majority of cells in the brain and spinal cord, including neurons and astrocytes, undergo little cellular division, acute effects of many chemotherapeutic agents are less prominent in the central nervous system (CNS) than in other organs. Another factor protecting the CNS from toxicity is the blood-brain barrier (BBB), which limits the amount of ionized and water-soluble drug that can reach the brain. Nonetheless, neurologic toxicity is frequently observed and is often the dose-limiting side effect of the treatment. |
Date |
2005 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
Walsh and Hoyt's Clinical Neuro-Ophthalmology, 6th Edition |
Relation is Part of |
Walsh and Hoyt's Clinical Neuro-Ophthalmology Walsh and Hoyt's Clinical Neuro-Ophthalmology |
Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh and Hoyt Textbook Selections Collection: https://NOVEL.utah.edu |
Publisher |
Wolters Kluwer Health, Philadelphia |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2005. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6kw8qjn |
Setname |
ehsl_novel_whts |
ID |
186606 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6kw8qjn |