Walsh & Hoyt: Histogenesis

Meningiomas may be attached to any of the three layers of the meninges. They originate from the arachnoid cap cells that line the outer surface of the arachnoid and are fused with the dural border cells to produce the interface layer between the dura and the arachnoid. Although some authors believe that these cells are derived from the neural crest and are thus of neuroectodermal origin, it appears more likely that they are of mesenchymal origin. Nevertheless, the possibility remains that neural crest elements contribute to the development of the meninges.