| Identifier |
20230315_nanos_neuroimmunology1_02 |
| Title |
MS Treatment/Immune System Targets |
| Creator |
Robert Shin, MD |
| Affiliation |
MedStar Georgetown University Hospital, Washington, DC |
| Subject |
Demyelination; Multiple Sclerosis; Disease-modifying Therapy; Relapsing; Progressive |
| Description |
First-generation injectable MS DMTs - Beta interferons and glatiramer acetate were the first MS disease modifying therapies, FDA-approved in the 1990s. They are only moderately effective compared to more modern MS treatment options, but they are felt to be generally safe and well-tolerated. Injection-related side effects are common. |
| Date |
2023-03 |
| References |
1. Birnbaum, G: Multiple Sclerosis. In: Bielekova B, Birnbaum G, Lisak RP, editors. Neuroimmunology. Oxford: Contemporary Neurology Series; 2019. 2. Fox RJ, Rae-Grant AD, Bethoux F. Multiple Sclerosis and Related Disorders: Clinical Guide to Diagnosis, Medical Management, and Rehabilitation. Springer: Demos Medical; 2019. 3. Kappos L, Fox RJ, et al. Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study A Randomized Clinical Trial. JAMA Neurol. 2021;78(5):558-567. Doi:10.1001/jamaneurol.2021.0405. 4. Giovannoni G, Comi G, et al. A Placebo-Controlled Trial of Oral Cladribine for Relapsing Multiple Sclerosis. N Engl J Med 2010;362:416-26. Doi: 10.1056/NEJMoa0902533. 5. Ryerson LZ, Li X, Goldberg JD, et al. Pharmacodynamics of natalizumab extended interval dosing in MS. Neurol Neuroimmunol Neuroinflamm 2020;7:e672. Doi:10.1212/NXI.0000000000000672. |
| Language |
eng |
| Format |
video/mp4 |
| Type |
Image/MovingImage |
| Source |
2023 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2023: Neuroimmunology: https://novel.utah.edu/collection/NAM/toc/ |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s62c5zjb |
| Setname |
ehsl_novel_nam |
| ID |
2386004 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s62c5zjb |
