The Miller Fisher Syndrome

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Identifier 19940302_nanos_clinaxonsympos_03
Title The Miller Fisher Syndrome
Creator Robert F. Saul
Affiliation Danville, PA
Subject Miller Fisher Syndrome; Guilllan-Barre' Syndrome; Cerebrospinal Fluid; Corticosteroids
Description Although variants of the Guilllan-Barre' syndrome (GBS) with ataxia, areflexia, and ophthalmoplegia were reported prior to 1956, Fisher, first described three cases with this distinct triad, without concomitant peripheral neuropathy, as a separate entity. Aa:ording to Berlit and Rakicky, there are 223 cases of the Miller Fisher syndrome reported between 1956 and 1992. Controversy still continues regarding the nature of the disease as a peripheral or central nervous system (CNS) disorder, or a combination of both. Although I will attempt to explore that more completely, it appears, at least in my experience, the disorder is one of a peripheral neuropathy. As with all syndromes, overlap signs and symptoms are seen, and in some cases an actual transition from the 'benign Fisher variant' to the more 'sinister GBS' occurs. Smith and Walsh coined the eponym bearing Fisher's name, attaching it to a syndrome outside his field of interest, stroke. The incidence of Fisher's syndrome is approximately 5% of aU cases repo ed with GBS. The male/female ratio is about 2: I, and the mean age is said to be 43.6 years. Of the 223 cases reported prior to 1993, 14.3% were children, the youngest being 14 months, and the oldest 80 years of age. In the 12 personal cases I could pull from my files the youngest was 2 l/2 years and the oldest 76 years old.
Date 1994-03-02
Language eng
Format application/pdf
Type Text
Source 1994 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 1994: Clinical Presentations (Session II)
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 1994. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6qv6t53
Setname ehsl_novel_nam
ID 182802
Reference URL https://collections.lib.utah.edu/ark:/87278/s6qv6t53
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